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The map label for this gene is fhuG [H]

Identifier: 49183362

GI number: 49183362

Start: 360086

End: 361093

Strand: Reverse

Name: fhuG [H]

Synonym: BAS0334

Alternate gene names: 49183362

Gene position: 361093-360086 (Counterclockwise)

Preceding gene: 49183363

Following gene: 49183358

Centisome position: 6.91

GC content: 38.49

Gene sequence:

>1008_bases
ATGATACCATCTATTCTAAGAAAACAACGTCTTATCATACTCGCTTTACTTATACTAACCATTACAACCATTGTAATTGG
AATGGGGCTCGGTTCAGCATCTTTATCTTATGATCGGCTACTCCCAATATTAATGGGCCAAGGAACTTTTAAAGAGGAGT
TTGTTTTATACTCTTTAAGGCTACCTAGAATTATCATTACATTATTAGCTGGTATGGCTCTTGCTTTATCAGGAGCTATT
CTGCAAGGAATTACCCGAAATGATTTAGCTGAACCTGGTATTCTCGGTATCAACTCTGGGGCCGGTGTTGCTGTTGCTAT
TTTCTTTTTATACTTTCCAATAGATGTAGGTTCATTTCTTTACTTACTACCTGTCGTTGGATTTATCGGGGCATTTCTGA
CAGCTGTTCTCATTTACGTATTTTCATATAGTAAATCAAGTGGACTTCAGCCGGTACGATTAACATTAACCGGTATCGGT
TTTGCCTTTGCACTATCTGGAATGATGATTGTCCTTATTTCATCCGCAGATCGCATGAAAGTAGACTTTATTTCAAAATG
GATTGCAGGAAACATTTGGGGAGACGATTGGATCTTCATTTTCGCAATGCTCCCATGGTTAATCGTATTAATTCCATTTG
TTTTCTATAAAGCAAATCGATTAAACATTTTAGCATTAAACGAACCAGTCGCAATTGGCGTTGGAATTGAAATTGAAAAA
GAGCGTAGATATTTATTAGTTGCAGCCGTTGCACTTGCTGCTGCCGCTGTTTCTGTAACAGGAGGAATTAGCTTTATCGG
ACTGATGGCTCCTCATATCGCGAAATCTTTAGTAGGTCCAAGACATCAAATCTTCATGCCTATCGCCCTTTTAATCGGTG
GATGGCTATTGCTACTAGCAGACACAATTGGACGAAATATCGTTGAACCTAACGGTATCCCAGCAGGTATTGTTGTCGCT
TTAATTGGTGCTCCTTACTTTATGTATTTGTTGCTTAAAAAAGCGTAA

Upstream 100 bases:

>100_bases
CGATTAACGCTCCGTACGAAACACCAGTTGCCGCTATTGTCGCAATTGTAGGATTACCATTCTTCCTATTCATTGTACGT
AAAGGAGGAAAAACGTTCTC

Downstream 100 bases:

>100_bases
AGAAACACCCTCAAGATCTTTTCTTGAGGGTGTTTTTATTCTACTGCTGCCCATACCCTTCAAACTTCTTCGCCAAATTC
TCCATCTCGTCTTCTGGCAA

Product: iron compound ABC transporter permease

Products: ADP; phosphate; iron dicitrate [Cytoplasm] [C]

Alternate protein names: Ferric hydroxamate uptake protein G; Ferrichrome transport system permease protein fhuG; Iron(III)-hydroxamate import system permease protein fhuG [H]

Number of amino acids: Translated: 335; Mature: 335

Protein sequence:

>335_residues
MIPSILRKQRLIILALLILTITTIVIGMGLGSASLSYDRLLPILMGQGTFKEEFVLYSLRLPRIIITLLAGMALALSGAI
LQGITRNDLAEPGILGINSGAGVAVAIFFLYFPIDVGSFLYLLPVVGFIGAFLTAVLIYVFSYSKSSGLQPVRLTLTGIG
FAFALSGMMIVLISSADRMKVDFISKWIAGNIWGDDWIFIFAMLPWLIVLIPFVFYKANRLNILALNEPVAIGVGIEIEK
ERRYLLVAAVALAAAAVSVTGGISFIGLMAPHIAKSLVGPRHQIFMPIALLIGGWLLLLADTIGRNIVEPNGIPAGIVVA
LIGAPYFMYLLLKKA

Sequences:

>Translated_335_residues
MIPSILRKQRLIILALLILTITTIVIGMGLGSASLSYDRLLPILMGQGTFKEEFVLYSLRLPRIIITLLAGMALALSGAI
LQGITRNDLAEPGILGINSGAGVAVAIFFLYFPIDVGSFLYLLPVVGFIGAFLTAVLIYVFSYSKSSGLQPVRLTLTGIG
FAFALSGMMIVLISSADRMKVDFISKWIAGNIWGDDWIFIFAMLPWLIVLIPFVFYKANRLNILALNEPVAIGVGIEIEK
ERRYLLVAAVALAAAAVSVTGGISFIGLMAPHIAKSLVGPRHQIFMPIALLIGGWLLLLADTIGRNIVEPNGIPAGIVVA
LIGAPYFMYLLLKKA
>Mature_335_residues
MIPSILRKQRLIILALLILTITTIVIGMGLGSASLSYDRLLPILMGQGTFKEEFVLYSLRLPRIIITLLAGMALALSGAI
LQGITRNDLAEPGILGINSGAGVAVAIFFLYFPIDVGSFLYLLPVVGFIGAFLTAVLIYVFSYSKSSGLQPVRLTLTGIG
FAFALSGMMIVLISSADRMKVDFISKWIAGNIWGDDWIFIFAMLPWLIVLIPFVFYKANRLNILALNEPVAIGVGIEIEK
ERRYLLVAAVALAAAAVSVTGGISFIGLMAPHIAKSLVGPRHQIFMPIALLIGGWLLLLADTIGRNIVEPNGIPAGIVVA
LIGAPYFMYLLLKKA

Specific function: Part of the ABC transporter complex fhuBGCD involved in iron(3+)-hydroxamate import. Responsible for the translocation of the substrate across the membrane [H]

COG id: COG0609

COG function: function code P; ABC-type Fe3+-siderophore transport system, permease component

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790740, Length=287, Percent_Identity=34.1463414634146, Blast_Score=164, Evalue=1e-41,
Organism=Escherichia coli, GI1786347, Length=331, Percent_Identity=31.7220543806647, Blast_Score=128, Evalue=4e-31,
Organism=Escherichia coli, GI1790741, Length=298, Percent_Identity=32.5503355704698, Blast_Score=123, Evalue=2e-29,
Organism=Escherichia coli, GI1788004, Length=285, Percent_Identity=32.280701754386, Blast_Score=115, Evalue=6e-27,
Organism=Escherichia coli, GI1786805, Length=317, Percent_Identity=36.2776025236593, Blast_Score=113, Evalue=1e-26,
Organism=Escherichia coli, GI1786804, Length=330, Percent_Identity=29.0909090909091, Blast_Score=109, Evalue=2e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000522 [H]

Pfam domain/function: PF01032 FecCD [H]

EC number: NA

Molecular weight: Translated: 36074; Mature: 36074

Theoretical pI: Translated: 10.02; Mature: 10.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIPSILRKQRLIILALLILTITTIVIGMGLGSASLSYDRLLPILMGQGTFKEEFVLYSLR
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHH
LPRIIITLLAGMALALSGAILQGITRNDLAEPGILGINSGAGVAVAIFFLYFPIDVGSFL
HHHHHHHHHHHHHHHHHHHHHHCCCHHCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHH
YLLPVVGFIGAFLTAVLIYVFSYSKSSGLQPVRLTLTGIGFAFALSGMMIVLISSADRMK
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEHHHHHHHHHHHHHEEEECCCCCHH
VDFISKWIAGNIWGDDWIFIFAMLPWLIVLIPFVFYKANRLNILALNEPVAIGVGIEIEK
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCEEEEECEEEEC
ERRYLLVAAVALAAAAVSVTGGISFIGLMAPHIAKSLVGPRHQIFMPIALLIGGWLLLLA
CCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
DTIGRNIVEPNGIPAGIVVALIGAPYFMYLLLKKA
HHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MIPSILRKQRLIILALLILTITTIVIGMGLGSASLSYDRLLPILMGQGTFKEEFVLYSLR
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHH
LPRIIITLLAGMALALSGAILQGITRNDLAEPGILGINSGAGVAVAIFFLYFPIDVGSFL
HHHHHHHHHHHHHHHHHHHHHHCCCHHCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHH
YLLPVVGFIGAFLTAVLIYVFSYSKSSGLQPVRLTLTGIGFAFALSGMMIVLISSADRMK
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEHHHHHHHHHHHHHEEEECCCCCHH
VDFISKWIAGNIWGDDWIFIFAMLPWLIVLIPFVFYKANRLNILALNEPVAIGVGIEIEK
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCEEEEECEEEEC
ERRYLLVAAVALAAAAVSVTGGISFIGLMAPHIAKSLVGPRHQIFMPIALLIGGWLLLLA
CCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
DTIGRNIVEPNGIPAGIVVALIGAPYFMYLLLKKA
HHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; iron dicitrate [Periplasm]; H2O [C]

Specific reaction: ATP + iron dicitrate [Periplasm] + H2O = ADP + phosphate + iron dicitrate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9639930; 9384377 [H]