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The map label for this gene is tatD [H]

Identifier: 46447478

GI number: 46447478

Start: 2204540

End: 2205337

Strand: Reverse

Name: tatD [H]

Synonym: pc1844

Alternate gene names: 46447478

Gene position: 2205337-2204540 (Counterclockwise)

Preceding gene: 46447479

Following gene: 46447477

Centisome position: 91.34

GC content: 37.22

Gene sequence:

>798_bases
ATGGATAGAATGAGCTATTCTCTTTCATTTATTGACTCTCACGCCCATTTAACAAGTTCTCCTGTTTACGAACAAATCGA
TGTTCTTTTGGAAAGAGCGCAAAAAGAGCACGTTCATCAAATAGTCAATATTTGTACTGATCCCGAGTCGTTAAAAAAAG
GGATAGAACTTTCCAAAAAATATCCTTGGATTTTCCAAACGGCTGCAACCCCTCCCAATAATGTACAAAAAGAAGGTGAA
GCAGCATTTGAAACGATTGCAGATTATGCTCGTAAAGGTTATTTAAAAGCGATTGGAGAAACAGGATTAGATTATTATTA
TGATTACTCTTCAAAAGAGATTCAAAAAGACTTCTTCCATCGTTATTTGCATTTAGCTCTTGAATGTCGATTACCTGTAG
TCATTCATTGTCGAGAGGCTTTTGCAGATTTTTTTGAAATTATTGACGCAGAATATCGAATTGACTGTCGTCATGCTCCA
GGTGTTTTACACTGTTTCACAGGAACAATTGCAGAAGCTGAAGAGGTCATTAAAAGAGGGTGGATGCTCTCTCTAAGTGG
GATTGTCACTTTTAAAAAAAGTTTTGAGTTGCAGCAAGTTGCAAAAGAAGTTCCTCTGTCCCAATTATTGATTGAAACAG
ATACGCCATATCTAGCCCCTCAAAAATATCGGGGCCACCCCAATGAGCCTTCTTATATCATAGAGACAGCTCGTTTGATT
GCATCTTTAAAAGGTATTTCTCTAGAGGAAGTGGCACATGCGACTTCTGAAAATGCACGTTATTTATTTCGAATTTAA

Upstream 100 bases:

>100_bases
GAAGTGATCAGAAGCAAGAGCCTACTATTTTACCTCAAGTACTCACTTCTGATATTGTCAAAGAACACATTAATTCAGTT
TTGAATTCTAAAGAGGTAGC

Downstream 100 bases:

>100_bases
TGATATAAATTTATTTGTTGAAAGTGTTAAATATTTTTTTACGATCCATTTTTGAAATTATATTTAAATTTTTTGACATT
TAATGATTGTAAAAATTAAT

Product: putative deoxyribonuclease TatD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 265; Mature: 265

Protein sequence:

>265_residues
MDRMSYSLSFIDSHAHLTSSPVYEQIDVLLERAQKEHVHQIVNICTDPESLKKGIELSKKYPWIFQTAATPPNNVQKEGE
AAFETIADYARKGYLKAIGETGLDYYYDYSSKEIQKDFFHRYLHLALECRLPVVIHCREAFADFFEIIDAEYRIDCRHAP
GVLHCFTGTIAEAEEVIKRGWMLSLSGIVTFKKSFELQQVAKEVPLSQLLIETDTPYLAPQKYRGHPNEPSYIIETARLI
ASLKGISLEEVAHATSENARYLFRI

Sequences:

>Translated_265_residues
MDRMSYSLSFIDSHAHLTSSPVYEQIDVLLERAQKEHVHQIVNICTDPESLKKGIELSKKYPWIFQTAATPPNNVQKEGE
AAFETIADYARKGYLKAIGETGLDYYYDYSSKEIQKDFFHRYLHLALECRLPVVIHCREAFADFFEIIDAEYRIDCRHAP
GVLHCFTGTIAEAEEVIKRGWMLSLSGIVTFKKSFELQQVAKEVPLSQLLIETDTPYLAPQKYRGHPNEPSYIIETARLI
ASLKGISLEEVAHATSENARYLFRI
>Mature_265_residues
MDRMSYSLSFIDSHAHLTSSPVYEQIDVLLERAQKEHVHQIVNICTDPESLKKGIELSKKYPWIFQTAATPPNNVQKEGE
AAFETIADYARKGYLKAIGETGLDYYYDYSSKEIQKDFFHRYLHLALECRLPVVIHCREAFADFFEIIDAEYRIDCRHAP
GVLHCFTGTIAEAEEVIKRGWMLSLSGIVTFKKSFELQQVAKEVPLSQLLIETDTPYLAPQKYRGHPNEPSYIIETARLI
ASLKGISLEEVAHATSENARYLFRI

Specific function: Unknown

COG id: COG0084

COG function: function code L; Mg-dependent DNase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tatD DNase family [H]

Homologues:

Organism=Homo sapiens, GI110349730, Length=274, Percent_Identity=29.5620437956204, Blast_Score=103, Evalue=1e-22,
Organism=Homo sapiens, GI110349734, Length=274, Percent_Identity=29.1970802919708, Blast_Score=100, Evalue=1e-21,
Organism=Homo sapiens, GI226061853, Length=277, Percent_Identity=29.6028880866426, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI225903424, Length=179, Percent_Identity=31.2849162011173, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI226061614, Length=268, Percent_Identity=27.6119402985075, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI226061595, Length=238, Percent_Identity=26.4705882352941, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI225903439, Length=196, Percent_Identity=28.5714285714286, Blast_Score=75, Evalue=4e-14,
Organism=Homo sapiens, GI14042943, Length=196, Percent_Identity=28.5714285714286, Blast_Score=75, Evalue=5e-14,
Organism=Escherichia coli, GI1787342, Length=260, Percent_Identity=34.6153846153846, Blast_Score=152, Evalue=2e-38,
Organism=Escherichia coli, GI48994985, Length=262, Percent_Identity=30.5343511450382, Blast_Score=116, Evalue=2e-27,
Organism=Escherichia coli, GI87082439, Length=258, Percent_Identity=26.7441860465116, Blast_Score=112, Evalue=3e-26,
Organism=Caenorhabditis elegans, GI17559024, Length=283, Percent_Identity=26.5017667844523, Blast_Score=117, Evalue=6e-27,
Organism=Caenorhabditis elegans, GI71980746, Length=269, Percent_Identity=28.2527881040892, Blast_Score=103, Evalue=9e-23,
Organism=Caenorhabditis elegans, GI17543026, Length=228, Percent_Identity=29.3859649122807, Blast_Score=87, Evalue=9e-18,
Organism=Caenorhabditis elegans, GI17565396, Length=195, Percent_Identity=32.3076923076923, Blast_Score=86, Evalue=3e-17,
Organism=Drosophila melanogaster, GI24648690, Length=287, Percent_Identity=30.3135888501742, Blast_Score=107, Evalue=1e-23,
Organism=Drosophila melanogaster, GI221330018, Length=231, Percent_Identity=25.974025974026, Blast_Score=90, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24586117, Length=201, Percent_Identity=26.865671641791, Blast_Score=87, Evalue=1e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015992
- InterPro:   IPR001130
- InterPro:   IPR018228
- InterPro:   IPR012278
- InterPro:   IPR015991 [H]

Pfam domain/function: PF01026 TatD_DNase [H]

EC number: 3.1.21.-

Molecular weight: Translated: 30368; Mature: 30368

Theoretical pI: Translated: 6.13; Mature: 6.13

Prosite motif: PS01091 TATD_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDRMSYSLSFIDSHAHLTSSPVYEQIDVLLERAQKEHVHQIVNICTDPESLKKGIELSKK
CCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCC
YPWIFQTAATPPNNVQKEGEAAFETIADYARKGYLKAIGETGLDYYYDYSSKEIQKDFFH
CCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCHHHHHHHHHH
RYLHLALECRLPVVIHCREAFADFFEIIDAEYRIDCRHAPGVLHCFTGTIAEAEEVIKRG
HHHHHHHHCCCCCEEEHHHHHHHHHHHHCCHHEEECCCCCCEEEHHHCCHHHHHHHHHCC
WMLSLSGIVTFKKSFELQQVAKEVPLSQLLIETDTPYLAPQKYRGHPNEPSYIIETARLI
CEEEHHHHHHHHHHHHHHHHHHHCCHHHHHEECCCCCCCCCCCCCCCCCCHHHHHHHHHH
ASLKGISLEEVAHATSENARYLFRI
HHHCCCCHHHHHHHHCCCCEEEEEC
>Mature Secondary Structure
MDRMSYSLSFIDSHAHLTSSPVYEQIDVLLERAQKEHVHQIVNICTDPESLKKGIELSKK
CCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCC
YPWIFQTAATPPNNVQKEGEAAFETIADYARKGYLKAIGETGLDYYYDYSSKEIQKDFFH
CCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCHHHHHHHHHH
RYLHLALECRLPVVIHCREAFADFFEIIDAEYRIDCRHAPGVLHCFTGTIAEAEEVIKRG
HHHHHHHHCCCCCEEEHHHHHHHHHHHHCCHHEEECCCCCCEEEHHHCCHHHHHHHHHCC
WMLSLSGIVTFKKSFELQQVAKEVPLSQLLIETDTPYLAPQKYRGHPNEPSYIIETARLI
CEEEHHHHHHHHHHHHHHHHHHHCCHHHHHEECCCCCCCCCCCCCCCCCCHHHHHHHHHH
ASLKGISLEEVAHATSENARYLFRI
HHHCCCCHHHHHHHHCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377 [H]