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The map label for this gene is clpC [H]

Identifier: 46447145

GI number: 46447145

Start: 1805005

End: 1807548

Strand: Reverse

Name: clpC [H]

Synonym: pc1511

Alternate gene names: 46447145

Gene position: 1807548-1805005 (Counterclockwise)

Preceding gene: 46447146

Following gene: 46447135

Centisome position: 74.86

GC content: 38.56

Gene sequence:

>2544_bases
ATGTTTGATAAATTTACGAATCGTGCAAAACAGGTTATTAAATTAGCCAAAAAAGAAGCGCAGCGACTTAATCATAATTA
TTTAGGCACAGAGCATGTCCTTTTAGGACTACTTAAACTAGGCCAAGGCGTTGCGGTTAACGTTTTACGAAACCTTAATA
TTGATTTTGAAACCGTGCGCAGTGAAGTAGAAAAATTAGTGGGATACGGACCTGAAATCCAAGTTTACGGAGATCCAGCC
TTAACTGGAAAAGTAAAAAAAGTTTTTGAGTTTGCAAATGAAGAAGCAGCCAATCTAAATCATAATTATGTGGGGACAGA
GCATTTATTGCTTGGTTTATTAAGACAAACAGATGGCGTTGCCGCACAAGTTCTAGAAAATTTAAATGTCAATTTGAAAG
AAGTGCGTAAAGAGGTTTTAAAAGAACTTGAAACTTTTAACTTACAACTTCCTCCCATTAGTGGAGCTGGTATTAGTCCA
AGTAACCCATCACCTGGCAGTGGGGGAAAAGGTTCTTACGAAAAAGTAGCTGCTGGAACTGCTAATGATAAAATGCCGGC
TTTAAGAGCTTATGGACACGATCTAACTGAAATGTGTCGCGAAGGCAAGATGGATCCGGTCATAGGTCGAAAAGAAGAAA
TTGAGCGACTCATTTTAATTCTGTGTCGGCGTCGAAAAAATAATCCAGTTTTAGTCGGAGAAGCAGGAGTCGGTAAAACT
GCCATAGTAGAAGGGCTTGCTCAAGCTATTGTAAAAGGGGATGTGCCTGATACTTTACGTAAGAAAAAATTAATTACACT
TGATTTAGCTTTAATGATTGCCGGTACTAAATACAGAGGACAATTTGAAGAACGTATTAAAGCTGTTATGGATGAAATCA
AGAAAAATGGAAATGTTTTACTGTTTATTGATGAATTGCATACAATTGTTGGCGCAGGTGCTGCTGAAGGAGCTATAGAT
GCTTCAAATATCTTAAAACCAGCTCTTTCTCGTGGAGAATTGCAATGTATTGGCGCAACAACAATTGATGAATATCGGAA
GCACATTGAAAAAGATGCAGCTTTAGAACGTCGCTTCCAAAAAATCTTAGTTGCTCCTCCAAGTGTTGATGATACTATTG
AAATTCTTTATGGTTTAAAACCTGAGTATGAGAAACATCATAAAGTCATTTTCACTAACCAAGCAATTCGTGCTGCCGCG
GTCTTATCGGATCGCTATATTCATGGGCGTTTTCTACCAGATAAGGCGATTGATTTAATTGATGAGGCAGGCGCCAAACT
GCGTATCTCTATGATGAATCAGCCACAAGACATTAGTAAGTATGAGTCAGAAATAGAGGCCACAAGGTTGGCTAAAGAAG
AATCTATTGGTAAGCAAGAGTATGAAAAAGCTGCCAAATTACGTGATAAAGAGAAAACCTTGCGTGAGCAGTTACAACAA
ATTCGAGCTGAATGGGAAATTAACAAAGAAGAGCATGAAGTCATTGTTGAGGATGAGGATGTAGCAAATGTGATAGCAAG
GCAAACAGGAATACCTCTCAATCGATTAACTGAAGGTGAACTACAAAAAGTTCTCAAAATGGAAGAGATCTTAAAAGAAG
GAATTATTGGCCAAGAAGACGCTATCAAAACAGTTTGCCGTGCCATTCGTCGAAGTAGAGCTGACATTAAAGATCCAAAT
CGTCCTATTGGAGCTTTTCTCTTTTTAGGTCCTACAGGAGTTGGGAAGACACTTTTAGCTAGGCTTTTGGCAATTAACAT
GTTCGGCGGCGAAGATGCACTCATTCAAGTCGATATGTCGGAATATATGGAAAAATTTGCCGTCAGTCGCATGACAGGTT
CTCCTCCTGGCTATGTAGGGCATGAAGAAGGCGGACAGCTAACAGAACAAGTTAGACAGCGACCTTACTCAGTGGTCCTG
TTTGATGAAATTGAGAAAGGACACCCTGATGTCATGGATCTTCTGTTACAAATACTTGAAGAAGGGCGTTTGACAGATTC
TTTTGGAAGAAGAGTTGATTTCCGAAATACAATTATTATCATGACCTCTAACTTGGGGGCTGATCTTATTAAGAAAAGTA
CTGAGATTGGTTTTGGAGCATCTGAAGGGTCGTTAGATTATATTCATATTAAGGAGAAAATTGAAAGCGAAGTCAAAAAA
CGATTTAAACCTGAATTTCTTAACCGTTTGAATGACATCGTTATTTTCCATCCGCTTAATCGAGACAATTTATTGCATGT
GATTTCTTTAGAAATTGAAAAACTTAGCAAACGTCTAGCTCGACGCGAAATATTTATCGAGCTTGATGATGCGGCTAAGA
ATTTCTTGGTAGATAAAGGCTTCCAAGTAGAAATGGGAGCTCGTCCATTAAGACGTACCATTGAACAATTCTTAGAGGAT
CCTTTAGCAGAGCGGATTTTGATGAATCCTAATGAAGGACGTCGTTGTCATGTGACAGTGGAAAACGAAGAGATTGTCAT
TATTGACGATGAAATTTATCCTCTTCATGGAAAATCTACTACTGCTAGTTCTGCAATCAATTGA

Upstream 100 bases:

>100_bases
TTGCAGCGAAAGAGTCTTTTGCACTTTATTCAATGGTTCAATGATAATAGACCATCATTAAATCAAAGCATCTGATATTC
TAAAAAAAAGCGAGTTCAAC

Downstream 100 bases:

>100_bases
AATTAAAAGGTAGCTCAATAATTCTTTTGAGCTACCCTTTTCAAAAAAGACTGAAAATCTTTCCGAGTCTCACTATAATT
TTTTATTTGTTGCCACCGCC

Product: endopeptidase ATP-binding chain clpC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 847; Mature: 847

Protein sequence:

>847_residues
MFDKFTNRAKQVIKLAKKEAQRLNHNYLGTEHVLLGLLKLGQGVAVNVLRNLNIDFETVRSEVEKLVGYGPEIQVYGDPA
LTGKVKKVFEFANEEAANLNHNYVGTEHLLLGLLRQTDGVAAQVLENLNVNLKEVRKEVLKELETFNLQLPPISGAGISP
SNPSPGSGGKGSYEKVAAGTANDKMPALRAYGHDLTEMCREGKMDPVIGRKEEIERLILILCRRRKNNPVLVGEAGVGKT
AIVEGLAQAIVKGDVPDTLRKKKLITLDLALMIAGTKYRGQFEERIKAVMDEIKKNGNVLLFIDELHTIVGAGAAEGAID
ASNILKPALSRGELQCIGATTIDEYRKHIEKDAALERRFQKILVAPPSVDDTIEILYGLKPEYEKHHKVIFTNQAIRAAA
VLSDRYIHGRFLPDKAIDLIDEAGAKLRISMMNQPQDISKYESEIEATRLAKEESIGKQEYEKAAKLRDKEKTLREQLQQ
IRAEWEINKEEHEVIVEDEDVANVIARQTGIPLNRLTEGELQKVLKMEEILKEGIIGQEDAIKTVCRAIRRSRADIKDPN
RPIGAFLFLGPTGVGKTLLARLLAINMFGGEDALIQVDMSEYMEKFAVSRMTGSPPGYVGHEEGGQLTEQVRQRPYSVVL
FDEIEKGHPDVMDLLLQILEEGRLTDSFGRRVDFRNTIIIMTSNLGADLIKKSTEIGFGASEGSLDYIHIKEKIESEVKK
RFKPEFLNRLNDIVIFHPLNRDNLLHVISLEIEKLSKRLARREIFIELDDAAKNFLVDKGFQVEMGARPLRRTIEQFLED
PLAERILMNPNEGRRCHVTVENEEIVIIDDEIYPLHGKSTTASSAIN

Sequences:

>Translated_847_residues
MFDKFTNRAKQVIKLAKKEAQRLNHNYLGTEHVLLGLLKLGQGVAVNVLRNLNIDFETVRSEVEKLVGYGPEIQVYGDPA
LTGKVKKVFEFANEEAANLNHNYVGTEHLLLGLLRQTDGVAAQVLENLNVNLKEVRKEVLKELETFNLQLPPISGAGISP
SNPSPGSGGKGSYEKVAAGTANDKMPALRAYGHDLTEMCREGKMDPVIGRKEEIERLILILCRRRKNNPVLVGEAGVGKT
AIVEGLAQAIVKGDVPDTLRKKKLITLDLALMIAGTKYRGQFEERIKAVMDEIKKNGNVLLFIDELHTIVGAGAAEGAID
ASNILKPALSRGELQCIGATTIDEYRKHIEKDAALERRFQKILVAPPSVDDTIEILYGLKPEYEKHHKVIFTNQAIRAAA
VLSDRYIHGRFLPDKAIDLIDEAGAKLRISMMNQPQDISKYESEIEATRLAKEESIGKQEYEKAAKLRDKEKTLREQLQQ
IRAEWEINKEEHEVIVEDEDVANVIARQTGIPLNRLTEGELQKVLKMEEILKEGIIGQEDAIKTVCRAIRRSRADIKDPN
RPIGAFLFLGPTGVGKTLLARLLAINMFGGEDALIQVDMSEYMEKFAVSRMTGSPPGYVGHEEGGQLTEQVRQRPYSVVL
FDEIEKGHPDVMDLLLQILEEGRLTDSFGRRVDFRNTIIIMTSNLGADLIKKSTEIGFGASEGSLDYIHIKEKIESEVKK
RFKPEFLNRLNDIVIFHPLNRDNLLHVISLEIEKLSKRLARREIFIELDDAAKNFLVDKGFQVEMGARPLRRTIEQFLED
PLAERILMNPNEGRRCHVTVENEEIVIIDDEIYPLHGKSTTASSAIN
>Mature_847_residues
MFDKFTNRAKQVIKLAKKEAQRLNHNYLGTEHVLLGLLKLGQGVAVNVLRNLNIDFETVRSEVEKLVGYGPEIQVYGDPA
LTGKVKKVFEFANEEAANLNHNYVGTEHLLLGLLRQTDGVAAQVLENLNVNLKEVRKEVLKELETFNLQLPPISGAGISP
SNPSPGSGGKGSYEKVAAGTANDKMPALRAYGHDLTEMCREGKMDPVIGRKEEIERLILILCRRRKNNPVLVGEAGVGKT
AIVEGLAQAIVKGDVPDTLRKKKLITLDLALMIAGTKYRGQFEERIKAVMDEIKKNGNVLLFIDELHTIVGAGAAEGAID
ASNILKPALSRGELQCIGATTIDEYRKHIEKDAALERRFQKILVAPPSVDDTIEILYGLKPEYEKHHKVIFTNQAIRAAA
VLSDRYIHGRFLPDKAIDLIDEAGAKLRISMMNQPQDISKYESEIEATRLAKEESIGKQEYEKAAKLRDKEKTLREQLQQ
IRAEWEINKEEHEVIVEDEDVANVIARQTGIPLNRLTEGELQKVLKMEEILKEGIIGQEDAIKTVCRAIRRSRADIKDPN
RPIGAFLFLGPTGVGKTLLARLLAINMFGGEDALIQVDMSEYMEKFAVSRMTGSPPGYVGHEEGGQLTEQVRQRPYSVVL
FDEIEKGHPDVMDLLLQILEEGRLTDSFGRRVDFRNTIIIMTSNLGADLIKKSTEIGFGASEGSLDYIHIKEKIESEVKK
RFKPEFLNRLNDIVIFHPLNRDNLLHVISLEIEKLSKRLARREIFIELDDAAKNFLVDKGFQVEMGARPLRRTIEQFLED
PLAERILMNPNEGRRCHVTVENEEIVIIDDEIYPLHGKSTTASSAIN

Specific function: Part Of A Stress-Induced Multi-Chaperone System, It Is Involved In The Recovery Of The Cell From Heat-Induced Damage, In Cooperation With Dnak, Dnaj And Grpe. Acts Before Dnak, In The Processing Of Protein Aggregates. Protein Binding Stimulates The Atpase

COG id: COG0542

COG function: function code O; ATPases with chaperone activity, ATP-binding subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 UVR domain [H]

Homologues:

Organism=Homo sapiens, GI13540606, Length=338, Percent_Identity=37.8698224852071, Blast_Score=204, Evalue=2e-52,
Organism=Escherichia coli, GI1788943, Length=870, Percent_Identity=42.8735632183908, Blast_Score=675, Evalue=0.0,
Organism=Escherichia coli, GI1787109, Length=472, Percent_Identity=37.9237288135593, Blast_Score=301, Evalue=1e-82,
Organism=Saccharomyces cerevisiae, GI6320464, Length=708, Percent_Identity=45.9039548022599, Blast_Score=587, Evalue=1e-168,
Organism=Saccharomyces cerevisiae, GI6323002, Length=505, Percent_Identity=36.2376237623762, Blast_Score=291, Evalue=4e-79,

Paralogues:

None

Copy number: 560 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR003959
- InterPro:   IPR001270
- InterPro:   IPR019489
- InterPro:   IPR004176
- InterPro:   IPR023150
- InterPro:   IPR001943 [H]

Pfam domain/function: PF00004 AAA; PF07724 AAA_2; PF02861 Clp_N; PF10431 ClpB_D2-small; PF02151 UVR [H]

EC number: NA

Molecular weight: Translated: 94902; Mature: 94902

Theoretical pI: Translated: 6.28; Mature: 6.28

Prosite motif: PS50151 UVR ; PS00870 CLPAB_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFDKFTNRAKQVIKLAKKEAQRLNHNYLGTEHVLLGLLKLGQGVAVNVLRNLNIDFETVR
CCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCEEHHHHHCCCCHHHHH
SEVEKLVGYGPEIQVYGDPALTGKVKKVFEFANEEAANLNHNYVGTEHLLLGLLRQTDGV
HHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHCCHHCCCCCCCCCHHHHHHHHHHHCCCH
AAQVLENLNVNLKEVRKEVLKELETFNLQLPPISGAGISPSNPSPGSGGKGSYEKVAAGT
HHHHHHHCCCCHHHHHHHHHHHHHHCEEECCCCCCCCCCCCCCCCCCCCCCCHHHHHCCC
ANDKMPALRAYGHDLTEMCREGKMDPVIGRKEEIERLILILCRRRKNNPVLVGEAGVGKT
CCCCCCHHHHHCCHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCCCEEEECCCCCHH
AIVEGLAQAIVKGDVPDTLRKKKLITLDLALMIAGTKYRGQFEERIKAVMDEIKKNGNVL
HHHHHHHHHHHCCCCCHHHHHCHHHEEEHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCEE
LFIDELHTIVGAGAAEGAIDASNILKPALSRGELQCIGATTIDEYRKHIEKDAALERRFQ
EEEHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHHHHH
KILVAPPSVDDTIEILYGLKPEYEKHHKVIFTNQAIRAAAVLSDRYIHGRFLPDKAIDLI
HHEECCCCCCHHHHHHHCCCCCHHCCCEEEEECHHHHHHHHHHCCCCCCEECCHHHHHHH
DEAGAKLRISMMNQPQDISKYESEIEATRLAKEESIGKQEYEKAAKLRDKEKTLREQLQQ
HHCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
IRAEWEINKEEHEVIVEDEDVANVIARQTGIPLNRLTEGELQKVLKMEEILKEGIIGQED
HHHHCCCCCCCCEEEECCHHHHHHHHHHCCCCHHHCCHHHHHHHHHHHHHHHHCCCCCHH
AIKTVCRAIRRSRADIKDPNRPIGAFLFLGPTGVGKTLLARLLAINMFGGEDALIQVDMS
HHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHCCCCCCCEEEECHH
EYMEKFAVSRMTGSPPGYVGHEEGGQLTEQVRQRPYSVVLFDEIEKGHPDVMDLLLQILE
HHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHHHH
EGRLTDSFGRRVDFRNTIIIMTSNLGADLIKKSTEIGFGASEGSLDYIHIKEKIESEVKK
CCCCCHHHCCCCCCCCEEEEEECCCCHHHHHHHHCCCCCCCCCCEEEEEHHHHHHHHHHH
RFKPEFLNRLNDIVIFHPLNRDNLLHVISLEIEKLSKRLARREIFIELDDAAKNFLVDKG
CCCHHHHHHHCCEEEEECCCCCCEEEEEHHHHHHHHHHHHHHHEEEEECHHHHHHHHCCC
FQVEMGARPLRRTIEQFLEDPLAERILMNPNEGRRCHVTVENEEIVIIDDEIYPLHGKST
CEEECCCHHHHHHHHHHHHCHHHHHHCCCCCCCCEEEEEECCCEEEEECCCEEECCCCCC
TASSAIN
CCCCCCC
>Mature Secondary Structure
MFDKFTNRAKQVIKLAKKEAQRLNHNYLGTEHVLLGLLKLGQGVAVNVLRNLNIDFETVR
CCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCEEHHHHHCCCCHHHHH
SEVEKLVGYGPEIQVYGDPALTGKVKKVFEFANEEAANLNHNYVGTEHLLLGLLRQTDGV
HHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHCCHHCCCCCCCCCHHHHHHHHHHHCCCH
AAQVLENLNVNLKEVRKEVLKELETFNLQLPPISGAGISPSNPSPGSGGKGSYEKVAAGT
HHHHHHHCCCCHHHHHHHHHHHHHHCEEECCCCCCCCCCCCCCCCCCCCCCCHHHHHCCC
ANDKMPALRAYGHDLTEMCREGKMDPVIGRKEEIERLILILCRRRKNNPVLVGEAGVGKT
CCCCCCHHHHHCCHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCCCEEEECCCCCHH
AIVEGLAQAIVKGDVPDTLRKKKLITLDLALMIAGTKYRGQFEERIKAVMDEIKKNGNVL
HHHHHHHHHHHCCCCCHHHHHCHHHEEEHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCEE
LFIDELHTIVGAGAAEGAIDASNILKPALSRGELQCIGATTIDEYRKHIEKDAALERRFQ
EEEHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHHHHH
KILVAPPSVDDTIEILYGLKPEYEKHHKVIFTNQAIRAAAVLSDRYIHGRFLPDKAIDLI
HHEECCCCCCHHHHHHHCCCCCHHCCCEEEEECHHHHHHHHHHCCCCCCEECCHHHHHHH
DEAGAKLRISMMNQPQDISKYESEIEATRLAKEESIGKQEYEKAAKLRDKEKTLREQLQQ
HHCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
IRAEWEINKEEHEVIVEDEDVANVIARQTGIPLNRLTEGELQKVLKMEEILKEGIIGQED
HHHHCCCCCCCCEEEECCHHHHHHHHHHCCCCHHHCCHHHHHHHHHHHHHHHHCCCCCHH
AIKTVCRAIRRSRADIKDPNRPIGAFLFLGPTGVGKTLLARLLAINMFGGEDALIQVDMS
HHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHCCCCCCCEEEECHH
EYMEKFAVSRMTGSPPGYVGHEEGGQLTEQVRQRPYSVVLFDEIEKGHPDVMDLLLQILE
HHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHHHH
EGRLTDSFGRRVDFRNTIIIMTSNLGADLIKKSTEIGFGASEGSLDYIHIKEKIESEVKK
CCCCCHHHCCCCCCCCEEEEEECCCCHHHHHHHHCCCCCCCCCCEEEEEHHHHHHHHHHH
RFKPEFLNRLNDIVIFHPLNRDNLLHVISLEIEKLSKRLARREIFIELDDAAKNFLVDKG
CCCHHHHHHHCCEEEEECCCCCCEEEEEHHHHHHHHHHHHHHHEEEEECHHHHHHHHCCC
FQVEMGARPLRRTIEQFLEDPLAERILMNPNEGRRCHVTVENEEIVIIDDEIYPLHGKST
CEEECCCHHHHHHHHHHHHCHHHHHHCCCCCCCCEEEEEECCCEEEEECCCEEECCCCCC
TASSAIN
CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Serine endopeptidases [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10684935 [H]