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The map label for this gene is azr [H]

Identifier: 46446971

GI number: 46446971

Start: 1593986

End: 1594591

Strand: Reverse

Name: azr [H]

Synonym: pc1337

Alternate gene names: 46446971

Gene position: 1594591-1593986 (Counterclockwise)

Preceding gene: 46446972

Following gene: 46446965

Centisome position: 66.04

GC content: 37.79

Gene sequence:

>606_bases
ATGTTAAAATGGATGTTATGCATAGGTTTAGTTTTAACTAGTTCTTTAGCAGCAGAATTGAAAGTTCTGGCATTCTCGGG
AAGCACGCAAATAGATTCTTTGAATAAAAAGTTCGTGCACCAAGCGGCTAAAATAGCCGAAGAAATGGGAGCGAAGGTTC
AAATCATTGATCTTCGTGATTATTCTATTCCATTTTATGATGGAGATTTAGAAAACGCGAAAGGTTTACCAGAAAATGCT
AAAAAATTGCGTCAGCTGATGATGGAAAGCCAGGCAATTATTATTTCAACTCCAGAATATAATGGTTCTTTATCCGGTGT
TTTAAAAAATGCCATTGACTGGGCAACACGCAACGAACAAGGGAAGCCGTCTCGTGATGCTTTTACCGGTAAGAAATTTG
CTATTTTGAGTGCTTCTCCATCACCTAGTGGGGGTTCACATGCTCTTGATCATTTGCGTGCAGTGATTGAAGGTGTAGGG
GGAAAAGTTGTGTCTGAACAAGTGGCTTTGTCAAATGCTCATCAAGCGTTTGATTCTCAAGGAAATTTGCAAGATCCTAT
TATAAAAGAAAAGCTTAAAAAAGAAATTCAAGAACTTCTTCATTAA

Upstream 100 bases:

>100_bases
AGGTAAAAAATCATATTAAGTAAATTTTTAATGTGCCATCATTTTAATTCTCTGTAAATTGTTATGTCTAAAATATAAAA
TATTTAAATCGAGGTGAGTC

Downstream 100 bases:

>100_bases
TTTGAATAAAATCTATGATTGCCACCAGATATTCTGGGGCAATTGTAAGTGTAGGTGATAGAGTTACTTACATTTAACTC
TTTGGTATCTCTACCAAATG

Product: hypothetical protein

Products: NA

Alternate protein names: Azobenzene reductase [H]

Number of amino acids: Translated: 201; Mature: 201

Protein sequence:

>201_residues
MLKWMLCIGLVLTSSLAAELKVLAFSGSTQIDSLNKKFVHQAAKIAEEMGAKVQIIDLRDYSIPFYDGDLENAKGLPENA
KKLRQLMMESQAIIISTPEYNGSLSGVLKNAIDWATRNEQGKPSRDAFTGKKFAILSASPSPSGGSHALDHLRAVIEGVG
GKVVSEQVALSNAHQAFDSQGNLQDPIIKEKLKKEIQELLH

Sequences:

>Translated_201_residues
MLKWMLCIGLVLTSSLAAELKVLAFSGSTQIDSLNKKFVHQAAKIAEEMGAKVQIIDLRDYSIPFYDGDLENAKGLPENA
KKLRQLMMESQAIIISTPEYNGSLSGVLKNAIDWATRNEQGKPSRDAFTGKKFAILSASPSPSGGSHALDHLRAVIEGVG
GKVVSEQVALSNAHQAFDSQGNLQDPIIKEKLKKEIQELLH
>Mature_201_residues
MLKWMLCIGLVLTSSLAAELKVLAFSGSTQIDSLNKKFVHQAAKIAEEMGAKVQIIDLRDYSIPFYDGDLENAKGLPENA
KKLRQLMMESQAIIISTPEYNGSLSGVLKNAIDWATRNEQGKPSRDAFTGKKFAILSASPSPSGGSHALDHLRAVIEGVG
GKVVSEQVALSNAHQAFDSQGNLQDPIIKEKLKKEIQELLH

Specific function: Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADPH, but not NADH, as an electron donor for its activity [H]

COG id: COG0431

COG function: function code R; Predicted flavoprotein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the azoreductase type 2 family [H]

Homologues:

Organism=Escherichia coli, GI1790149, Length=144, Percent_Identity=32.6388888888889, Blast_Score=72, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005025 [H]

Pfam domain/function: PF03358 FMN_red [H]

EC number: NA

Molecular weight: Translated: 21856; Mature: 21856

Theoretical pI: Translated: 7.72; Mature: 7.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKWMLCIGLVLTSSLAAELKVLAFSGSTQIDSLNKKFVHQAAKIAEEMGAKVQIIDLRD
CHHHHHHHHHHHHHHHHHHHEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCEEEEEEECC
YSIPFYDGDLENAKGLPENAKKLRQLMMESQAIIISTPEYNGSLSGVLKNAIDWATRNEQ
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCEEEEECCCCCCHHHHHHHHHHHHHHCCCC
GKPSRDAFTGKKFAILSASPSPSGGSHALDHLRAVIEGVGGKVVSEQVALSNAHQAFDSQ
CCCCCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCC
GNLQDPIIKEKLKKEIQELLH
CCCCCHHHHHHHHHHHHHHHC
>Mature Secondary Structure
MLKWMLCIGLVLTSSLAAELKVLAFSGSTQIDSLNKKFVHQAAKIAEEMGAKVQIIDLRD
CHHHHHHHHHHHHHHHHHHHEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCEEEEEEECC
YSIPFYDGDLENAKGLPENAKKLRQLMMESQAIIISTPEYNGSLSGVLKNAIDWATRNEQ
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCEEEEECCCCCCHHHHHHHHHHHHHHCCCC
GKPSRDAFTGKKFAILSASPSPSGGSHALDHLRAVIEGVGGKVVSEQVALSNAHQAFDSQ
CCCCCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCC
GNLQDPIIKEKLKKEIQELLH
CCCCCHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377 [H]