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The map label for this gene is tag [H]

Identifier: 46446972

GI number: 46446972

Start: 1594745

End: 1595311

Strand: Reverse

Name: tag [H]

Synonym: pc1338

Alternate gene names: 46446972

Gene position: 1595311-1594745 (Counterclockwise)

Preceding gene: 46446973

Following gene: 46446971

Centisome position: 66.07

GC content: 37.74

Gene sequence:

>567_bases
ATGCTTAAACGCTGTGATTGGGTGCAATTAAACAACCCTTTGTATGTTGCTTACCATGACGAAGAATGGGGAATTCCGGT
TCATGATGACCATAAACATTTTGAATTTTTAATTTTAGAAGGAGCTCAAGCGGGATTGAGTTGGCAAACGGTTCTTCAAC
GACGTGAAAATTATCGGCAAGCCTTCGCCTCTTTCGATCCTCATATCGTTGCCACCTACGATGAGCAGAAAAAAAATGAG
TTACTTTTGCATCCGGGCATTATTCGTAATCGATTAAAAATTGAGTCAACAATTGCAAACGCAAAACACTTTTTAAAGGT
TCAAGAAGAATTTGGAAGCTTTAATACCTATATTTGGCAATTTGTAAACGGGAAACCCATCCAGAATCAATGGGAAACGA
TTAGGCAGGTACCTGCGGAAACAAAAGAATCTTTAGCTCTTAGTAAAGATTTGAAAAAAAGGGGATTTAAATTCGTTGGA
GCAACAATTATGTATGCTTATATGCAAGCTTGCGGATTGGTTAACGATCATACAATAGATTGCTTTTGCCATCCATCTAA
GCATTGA

Upstream 100 bases:

>100_bases
AACTAAATTAACTTATAAGTATGTTTTAACCCTAGATTGACAGGAAGGGTTTACTTCGTTATTTTTATTCCACATCTTAA
TTTTTAATCAGGTTTTTTAT

Downstream 100 bases:

>100_bases
GCATTCAATAAACGAATAAAATTTTTTTTATCAAAGAATAAAAGTAAATTGATAGGTAAAAAATCATATTAAGTAAATTT
TTAATGTGCCATCATTTTAA

Product: 3-methyladenine-DNA glycosylase I

Products: NA

Alternate protein names: GMP synthetase; Glutamine amidotransferase [H]

Number of amino acids: Translated: 188; Mature: 188

Protein sequence:

>188_residues
MLKRCDWVQLNNPLYVAYHDEEWGIPVHDDHKHFEFLILEGAQAGLSWQTVLQRRENYRQAFASFDPHIVATYDEQKKNE
LLLHPGIIRNRLKIESTIANAKHFLKVQEEFGSFNTYIWQFVNGKPIQNQWETIRQVPAETKESLALSKDLKKRGFKFVG
ATIMYAYMQACGLVNDHTIDCFCHPSKH

Sequences:

>Translated_188_residues
MLKRCDWVQLNNPLYVAYHDEEWGIPVHDDHKHFEFLILEGAQAGLSWQTVLQRRENYRQAFASFDPHIVATYDEQKKNE
LLLHPGIIRNRLKIESTIANAKHFLKVQEEFGSFNTYIWQFVNGKPIQNQWETIRQVPAETKESLALSKDLKKRGFKFVG
ATIMYAYMQACGLVNDHTIDCFCHPSKH
>Mature_188_residues
MLKRCDWVQLNNPLYVAYHDEEWGIPVHDDHKHFEFLILEGAQAGLSWQTVLQRRENYRQAFASFDPHIVATYDEQKKNE
LLLHPGIIRNRLKIESTIANAKHFLKVQEEFGSFNTYIWQFVNGKPIQNQWETIRQVPAETKESLALSKDLKKRGFKFVG
ATIMYAYMQACGLVNDHTIDCFCHPSKH

Specific function: Catalyzes the synthesis of GMP from XMP [H]

COG id: COG2818

COG function: function code L; 3-methyladenine DNA glycosylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 3 N-acetyltransferase domains [H]

Homologues:

Organism=Escherichia coli, GI1789971, Length=185, Percent_Identity=51.8918918918919, Blast_Score=206, Evalue=6e-55,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000182
- InterPro:   IPR016181
- InterPro:   IPR005019
- InterPro:   IPR001962
- InterPro:   IPR001317
- InterPro:   IPR011257
- InterPro:   IPR017926
- InterPro:   IPR000991
- InterPro:   IPR001674
- InterPro:   IPR014729 [H]

Pfam domain/function: PF00583 Acetyltransf_1; PF03352 Adenine_glyco; PF00733 Asn_synthase; PF00117 GATase; PF00958 GMP_synt_C [H]

EC number: =6.3.5.2 [H]

Molecular weight: Translated: 22020; Mature: 22020

Theoretical pI: Translated: 7.66; Mature: 7.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKRCDWVQLNNPLYVAYHDEEWGIPVHDDHKHFEFLILEGAQAGLSWQTVLQRRENYRQ
CCCCCCEEEECCCEEEEEECCCCCCCCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHH
AFASFDPHIVATYDEQKKNELLLHPGIIRNRLKIESTIANAKHFLKVQEEFGSFNTYIWQ
HHHCCCCCEEEECCCCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEE
FVNGKPIQNQWETIRQVPAETKESLALSKDLKKRGFKFVGATIMYAYMQACGLVNDHTID
ECCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCEEE
CFCHPSKH
EEECCCCC
>Mature Secondary Structure
MLKRCDWVQLNNPLYVAYHDEEWGIPVHDDHKHFEFLILEGAQAGLSWQTVLQRRENYRQ
CCCCCCEEEECCCEEEEEECCCCCCCCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHH
AFASFDPHIVATYDEQKKNELLLHPGIIRNRLKIESTIANAKHFLKVQEEFGSFNTYIWQ
HHHCCCCCEEEECCCCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEE
FVNGKPIQNQWETIRQVPAETKESLALSKDLKKRGFKFVGATIMYAYMQACGLVNDHTID
ECCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCEEE
CFCHPSKH
EEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12810954 [H]