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The map label for this gene is lytF [C]

Identifier: 46446884

GI number: 46446884

Start: 1491127

End: 1491861

Strand: Reverse

Name: lytF [C]

Synonym: pc1250

Alternate gene names: 46446884

Gene position: 1491861-1491127 (Counterclockwise)

Preceding gene: 46446885

Following gene: 46446883

Centisome position: 61.79

GC content: 34.01

Gene sequence:

>735_bases
ATGACAAGAAAGGATACGATACTGATTGCTGTCGTTATCAATGCTGGATTGTTAGCGATTTTATTTGCGACAGCTATCAT
TTATGATACTGAAAAAGTGCTGGAGCAAAGCGAATTCAATTCTTCTTTAGCGGAGGCTAAAGAAATTCCTTTAACTGATC
CGGCTAATCATCTAGTCGCGACCGGACCAGTTATTGTGGACGAAGTTGATAATGTTTTAAAGTATTATTCTCAACCTTCT
TATTCATTAAAAATTGATCCTTCTGATTCTTATAATCCTGAATCTATCGTTGTTCAGGCGAGTCCTTCTGAAGACGATGA
GCCAATATCTGAATTTTCACCTAATTTTAAAGGTAATTTTGTTGAAATAACCGTTAAAAAAGGAGATGTATTAGAAAAGA
TTGCTCGTGCTAATGGGACAACGATTAATGCGATTAAGAAAGCAAATAACCTTCCCAACGAAAAGTTGTCAATAGGTCAA
GTTTTAAAAATTCCTTTGAATCAAGTTCAAGGGGCAATTGCAGCAAAAAGTGAAATATCTAAAAAGGATTTAGAGCAAAT
AGAAAATAATCAAAACTCATCCGAAGCTGTTTATTATATTGTTAAGAGCGGAGATAATCCTTGGAAAATTGCTAAACAAT
TTAATGTGAAATATGAGGATATTTTAAGGCTAAATCAATTAGATGAAGAAAAGGCTAGAAATTTGAAGATTGGGGATCGC
ATTCGCGTTAAGTAG

Upstream 100 bases:

>100_bases
TGATATGTTTAAAGATTATATCCATCGTGGAGAAGAGTTTAAAAGGCTCGTAAAACTTCTATAAATAAGAGAAATAAAAA
AAATAGAGAGGATAAATAAA

Downstream 100 bases:

>100_bases
CTGTTCATGACATTTTATCGGTCGTTACTATTATTTTGTGTGGCTTCGATCTTCGCGATGGGGCTAGTTATGATTTTTAA
TACCACTTCAGCAGAAGTTT

Product: putative muropeptidase (autolysin)

Products: 1,6-Anhydrobond In The Muramic Acid Residue [C]

Alternate protein names: Lytic Transglycosylase Catalytic; Cell Wall Hydrolase; Muropeptidase; Muramidase; Membrane-Bound Lytic Murein Transglycosylase D; LysM Domain-Containing Protein; Cell-Wall Associated Endopeptidase

Number of amino acids: Translated: 244; Mature: 243

Protein sequence:

>244_residues
MTRKDTILIAVVINAGLLAILFATAIIYDTEKVLEQSEFNSSLAEAKEIPLTDPANHLVATGPVIVDEVDNVLKYYSQPS
YSLKIDPSDSYNPESIVVQASPSEDDEPISEFSPNFKGNFVEITVKKGDVLEKIARANGTTINAIKKANNLPNEKLSIGQ
VLKIPLNQVQGAIAAKSEISKKDLEQIENNQNSSEAVYYIVKSGDNPWKIAKQFNVKYEDILRLNQLDEEKARNLKIGDR
IRVK

Sequences:

>Translated_244_residues
MTRKDTILIAVVINAGLLAILFATAIIYDTEKVLEQSEFNSSLAEAKEIPLTDPANHLVATGPVIVDEVDNVLKYYSQPS
YSLKIDPSDSYNPESIVVQASPSEDDEPISEFSPNFKGNFVEITVKKGDVLEKIARANGTTINAIKKANNLPNEKLSIGQ
VLKIPLNQVQGAIAAKSEISKKDLEQIENNQNSSEAVYYIVKSGDNPWKIAKQFNVKYEDILRLNQLDEEKARNLKIGDR
IRVK
>Mature_243_residues
TRKDTILIAVVINAGLLAILFATAIIYDTEKVLEQSEFNSSLAEAKEIPLTDPANHLVATGPVIVDEVDNVLKYYSQPSY
SLKIDPSDSYNPESIVVQASPSEDDEPISEFSPNFKGNFVEITVKKGDVLEKIARANGTTINAIKKANNLPNEKLSIGQV
LKIPLNQVQGAIAAKSEISKKDLEQIENNQNSSEAVYYIVKSGDNPWKIAKQFNVKYEDILRLNQLDEEKARNLKIGDRI
RVK

Specific function: Murein-Degrading Enzyme. May Play A Role In Recycling Of Muropeptides During Cell Elongation And/Or Cell Division (By Similarity). [C]

COG id: COG1388

COG function: function code M; FOG: LysM repeat

Gene ontology:

Cell location: Attached To The Membrane By A Lipid Anchor [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 3.2.1.- [C]

Molecular weight: Translated: 27059; Mature: 26928

Theoretical pI: Translated: 4.80; Mature: 4.80

Prosite motif: PS00430 TONB_DEPENDENT_REC_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.4 %Met     (Translated Protein)
0.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
0.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRKDTILIAVVINAGLLAILFATAIIYDTEKVLEQSEFNSSLAEAKEIPLTDPANHLVA
CCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEE
TGPVIVDEVDNVLKYYSQPSYSLKIDPSDSYNPESIVVQASPSEDDEPISEFSPNFKGNF
CCCCHHHHHHHHHHHHCCCCCEEEECCCCCCCCCEEEEEECCCCCCCCHHHCCCCCCCCE
VEITVKKGDVLEKIARANGTTINAIKKANNLPNEKLSIGQVLKIPLNQVQGAIAAKSEIS
EEEEECCCHHHHHHHHCCCCEEEHHHHHCCCCCCCCCHHHHEECCHHHHHHHHHHHHHCC
KKDLEQIENNQNSSEAVYYIVKSGDNPWKIAKQFNVKYEDILRLNQLDEEKARNLKIGDR
HHHHHHHHCCCCCCCEEEEEEECCCCCHHHHHHHCCCHHHHHHHHHCCHHHHCCCCCCCE
IRVK
EECC
>Mature Secondary Structure 
TRKDTILIAVVINAGLLAILFATAIIYDTEKVLEQSEFNSSLAEAKEIPLTDPANHLVA
CCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEE
TGPVIVDEVDNVLKYYSQPSYSLKIDPSDSYNPESIVVQASPSEDDEPISEFSPNFKGNF
CCCCHHHHHHHHHHHHCCCCCEEEECCCCCCCCCEEEEEECCCCCCCCHHHCCCCCCCCE
VEITVKKGDVLEKIARANGTTINAIKKANNLPNEKLSIGQVLKIPLNQVQGAIAAKSEIS
EEEEECCCHHHHHHHHCCCCEEEHHHHHCCCCCCCCCHHHHEECCHHHHHHHHHHHHHCC
KKDLEQIENNQNSSEAVYYIVKSGDNPWKIAKQFNVKYEDILRLNQLDEEKARNLKIGDR
HHHHHHHHCCCCCCCEEEEEEECCCCCHHHHHHHCCCHHHHHHHHHCCHHHHCCCCCCCE
IRVK
EECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Muramic Acid Residue (N-Acetylmuramic Acid And N-Acetylglucosamine Residues) [C]

Specific reaction: Cleavage Of The Beta-1,4-Glycosidic Bond Between N-Acetylmuramic Acid And N-Acetylglucosamine Residues, Thereby Conserving The Energy In A Newly Synthesized 1,6-Anhydrobond In The Muramic Acid Residue. [C]

General reaction: Cleavage Of The Beta-1,4-Glycosidic Bond [C]

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA