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The map label for this gene is ftsW [H]

Identifier: 46446883

GI number: 46446883

Start: 1490011

End: 1491120

Strand: Reverse

Name: ftsW [H]

Synonym: pc1249

Alternate gene names: 46446883

Gene position: 1491120-1490011 (Counterclockwise)

Preceding gene: 46446884

Following gene: 46446882

Centisome position: 61.76

GC content: 36.49

Gene sequence:

>1110_bases
ATGACATTTTATCGGTCGTTACTATTATTTTGTGTGGCTTCGATCTTCGCGATGGGGCTAGTTATGATTTTTAATACCAC
TTCAGCAGAAGTTTTAGATCTTGCGCTTAATAAAAGTACCCATCAGGCCTTATTAAAACAAATTTTTTATTGTTTGATAG
GATTAATCTTAGCTGGTTGTGTATGGCATTTGGGGTATCAGAAGGTCATTAGTTTTAGTCCCTATTTGTTAGTTTTTTTC
TGTTTTTTACTTGTTCTGACACTTATTCCAGGTTTAGGTAAAGAAGTTAATGGATCAAGGAGATGGATTGGTGTTGCAGG
ATTTTTTTTCCAACCTTCCGAATTTGTTAAATACATTGTTCCGGCTTATTTTATCTATCGAATGGAAAATATAGAGGGGG
AATCGCTAGGGTTAAAAGACTTTCTTAAACTGATCGCTCAAGTAGGAACCCCTATTTTCCTTATCTTAATAGAACCTAAT
AATGGGACGGCGGGTGTGATAGGCCTTGTTGTCATAGTCATGTGTGTGATGACAAAAATTCGATTTAAATATTGGGCTCT
TCCACTGATGTGTTTTATGGTGATTGGTGCAATTTCTGCTTATCATCTTCCTTACGTATCAGCAAGGTTAAAAGTTTATC
TTCATCCGGAACTAGATTTGAGAGGTAAAGGCCATCAACCTTATCAAGCAAAAATAGCTGCAGGTTCTGGGCAATTGTTA
GGAAGAGGGCCTGGGAATAGTTTGCAGAAATTAAGTTATCTTCCCGAAGCACAAAATGATTATATTGCGGCTATTTACGC
GGAAGAGTTTGGCTTTATAGGTGTAACAGCTTTAGTGATTCTTTATATGATTATTGGTTACGTGGGATTTTATATTGCTC
ATATTTCTTCAGACAGAAGAGGTTTTTATTTTGCGACGGCCATTACTTTTTTAATCTGTTTTCAAGCTTTTATGAATCTT
GGAGTTGTGTCTGGTTTATTGCCAAGTACAGGATTAAATCTTCCTTTTTTTAGCCAAGGTGGGACTTCATTAATGGCTAA
CATCGCAGGTCTCGGACTGTTATTAAATATTGCTCATCAGAGGAGTCAAGTATGTCTAAACGGTTTATGA

Upstream 100 bases:

>100_bases
TAATGTGAAATATGAGGATATTTTAAGGCTAAATCAATTAGATGAAGAAAAGGCTAGAAATTTGAAGATTGGGGATCGCA
TTCGCGTTAAGTAGCTGTTC

Downstream 100 bases:

>100_bases
TTACAGCTGGTGGGACGGGGGGGCATATTTTTCCTGCTCAAGGATTAGCACAAGAACTCATCAAAAAAACCTATTCTTCC
TCTATTTTGTTTGTTGCGGG

Product: putative cell division protein ftsW

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 369; Mature: 368

Protein sequence:

>369_residues
MTFYRSLLLFCVASIFAMGLVMIFNTTSAEVLDLALNKSTHQALLKQIFYCLIGLILAGCVWHLGYQKVISFSPYLLVFF
CFLLVLTLIPGLGKEVNGSRRWIGVAGFFFQPSEFVKYIVPAYFIYRMENIEGESLGLKDFLKLIAQVGTPIFLILIEPN
NGTAGVIGLVVIVMCVMTKIRFKYWALPLMCFMVIGAISAYHLPYVSARLKVYLHPELDLRGKGHQPYQAKIAAGSGQLL
GRGPGNSLQKLSYLPEAQNDYIAAIYAEEFGFIGVTALVILYMIIGYVGFYIAHISSDRRGFYFATAITFLICFQAFMNL
GVVSGLLPSTGLNLPFFSQGGTSLMANIAGLGLLLNIAHQRSQVCLNGL

Sequences:

>Translated_369_residues
MTFYRSLLLFCVASIFAMGLVMIFNTTSAEVLDLALNKSTHQALLKQIFYCLIGLILAGCVWHLGYQKVISFSPYLLVFF
CFLLVLTLIPGLGKEVNGSRRWIGVAGFFFQPSEFVKYIVPAYFIYRMENIEGESLGLKDFLKLIAQVGTPIFLILIEPN
NGTAGVIGLVVIVMCVMTKIRFKYWALPLMCFMVIGAISAYHLPYVSARLKVYLHPELDLRGKGHQPYQAKIAAGSGQLL
GRGPGNSLQKLSYLPEAQNDYIAAIYAEEFGFIGVTALVILYMIIGYVGFYIAHISSDRRGFYFATAITFLICFQAFMNL
GVVSGLLPSTGLNLPFFSQGGTSLMANIAGLGLLLNIAHQRSQVCLNGL
>Mature_368_residues
TFYRSLLLFCVASIFAMGLVMIFNTTSAEVLDLALNKSTHQALLKQIFYCLIGLILAGCVWHLGYQKVISFSPYLLVFFC
FLLVLTLIPGLGKEVNGSRRWIGVAGFFFQPSEFVKYIVPAYFIYRMENIEGESLGLKDFLKLIAQVGTPIFLILIEPNN
GTAGVIGLVVIVMCVMTKIRFKYWALPLMCFMVIGAISAYHLPYVSARLKVYLHPELDLRGKGHQPYQAKIAAGSGQLLG
RGPGNSLQKLSYLPEAQNDYIAAIYAEEFGFIGVTALVILYMIIGYVGFYIAHISSDRRGFYFATAITFLICFQAFMNLG
VVSGLLPSTGLNLPFFSQGGTSLMANIAGLGLLLNIAHQRSQVCLNGL

Specific function: May play an essential role not only during sporulation, but also during vegetative growth [H]

COG id: COG0772

COG function: function code D; Bacterial cell division membrane protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsW/rodA/spoVE family [H]

Homologues:

Organism=Escherichia coli, GI1786277, Length=370, Percent_Identity=30, Blast_Score=136, Evalue=3e-33,
Organism=Escherichia coli, GI1786853, Length=294, Percent_Identity=30.2721088435374, Blast_Score=112, Evalue=3e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001182
- InterPro:   IPR018365
- InterPro:   IPR013437
- InterPro:   IPR013438 [H]

Pfam domain/function: PF01098 FTSW_RODA_SPOVE [H]

EC number: NA

Molecular weight: Translated: 40724; Mature: 40593

Theoretical pI: Translated: 8.95; Mature: 8.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTFYRSLLLFCVASIFAMGLVMIFNTTSAEVLDLALNKSTHQALLKQIFYCLIGLILAGC
CHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
VWHLGYQKVISFSPYLLVFFCFLLVLTLIPGLGKEVNGSRRWIGVAGFFFQPSEFVKYIV
HHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEECCCCHHHHHHHHH
PAYFIYRMENIEGESLGLKDFLKLIAQVGTPIFLILIEPNNGTAGVIGLVVIVMCVMTKI
HHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHH
RFKYWALPLMCFMVIGAISAYHLPYVSARLKVYLHPELDLRGKGHQPYQAKIAAGSGQLL
HHHHHHHHHHHHHHHHHHHHHHCCHHEEEEEEEECCCCCCCCCCCCCCEEEEECCCCCEE
GRGPGNSLQKLSYLPEAQNDYIAAIYAEEFGFIGVTALVILYMIIGYVGFYIAHISSDRR
ECCCCCHHHHHHCCCCCCCCEEEEEEHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
GFYFATAITFLICFQAFMNLGVVSGLLPSTGLNLPFFSQGGTSLMANIAGLGLLLNIAHQ
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
RSQVCLNGL
HHHHHHCCC
>Mature Secondary Structure 
TFYRSLLLFCVASIFAMGLVMIFNTTSAEVLDLALNKSTHQALLKQIFYCLIGLILAGC
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
VWHLGYQKVISFSPYLLVFFCFLLVLTLIPGLGKEVNGSRRWIGVAGFFFQPSEFVKYIV
HHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEECCCCHHHHHHHHH
PAYFIYRMENIEGESLGLKDFLKLIAQVGTPIFLILIEPNNGTAGVIGLVVIVMCVMTKI
HHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHH
RFKYWALPLMCFMVIGAISAYHLPYVSARLKVYLHPELDLRGKGHQPYQAKIAAGSGQLL
HHHHHHHHHHHHHHHHHHHHHHCCHHEEEEEEEECCCCCCCCCCCCCCEEEEECCCCCEE
GRGPGNSLQKLSYLPEAQNDYIAAIYAEEFGFIGVTALVILYMIIGYVGFYIAHISSDRR
ECCCCCHHHHHHCCCCCCCCEEEEEEHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
GFYFATAITFLICFQAFMNLGVVSGLLPSTGLNLPFFSQGGTSLMANIAGLGLLLNIAHQ
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
RSQVCLNGL
HHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2115675; 3098901; 9384377; 8436954; 1391053 [H]