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The map label for this gene is tauC [C]

Identifier: 46446220

GI number: 46446220

Start: 721591

End: 723264

Strand: Direct

Name: tauC [C]

Synonym: pc0586

Alternate gene names: 46446220

Gene position: 721591-723264 (Clockwise)

Preceding gene: 46446219

Following gene: 46446221

Centisome position: 29.89

GC content: 34.89

Gene sequence:

>1674_bases
TTGATCGTCACTTGTACGTTCCTTTTCATTTTGTTTGTTTGGGAATTTTTTAGTTATTTTAATCCGAATTTGATTTGGGT
ATTACCTCCACCTTCTCAGATATTTAATCAATTAATAGAAAAACCGGATTGTTTTCTCTTTCACACTGGTGTAACCCTCA
AAGAGATTTTAGGAGGATTCGCCCTTGCATTTAGCGTGGCTTTCCCCCTTGCTTGGATCATGGATCATTTTTCGATTGCT
CGCAATTTCTTACAGCCATTTTTTGTGATTATACAATGTATTCCTATGTTTACCTTAGCCCCCATCATGATTATGTGGTT
TGGCTGGAGCTACATTGCTATCGCTATACCCACTGCTTTAATGATTTTTTTTCCGCTGACAATTACCCTTTTTCAAGGTT
TACGTTCAGTTCCTAAAGAATTGACTGATTATTTTATGATTAATCATGCAACTCATTGGCAGATATTTTGCAAATTAAAA
TTGCCTTGGTCTCTTCCTCATCTATTTAGTGGGTTGCGACTATCAGCTGCTATTGCAGGAATAGCGGCTATCGCAGGTGA
ATGGGCAGGAGCCCAAAATGGGTTAGGTGTTTTAATGGTTGAGAGTAGAAGAGACATGGATTTAGCAACAAATTTTGCAG
CCCTGTTTTGTCTGACATTGCTTAGCTATTTGATCTATTCTATAATTCTTTTGATAGAATATTTTATTTTAAAAAAAAGA
TTTTTTAAAATTTTGAAAGCGCACTTTACCTATTCTAGGTTAACTTATTCTATTGTGTTTGTGTTTTTTGTGGGATGTGG
AATTTTGATGGGATGCCATCGACAAGCTTCTTCCAAACCTCCTGTTAGACTTGTTTTAGATTGGTTACCAAATCCTAATC
ATATTCCTTTTTATGTGGGTATTCATAAGGGTTTCTTTCAAGAACATCACATTAACATTTCGATTAAGAAAATGCAGGAG
CCTGGCCATGCTACATCTTATTTATTATTAGACCAGTGTGAATTGGCGTTAGCCTATATGCCTCATACTATCCGTGTCGA
ACAAAAAAAAGGTGAGGTTGAGCCGATTGGAATTCTTATTCAAGAACCTCTAAATGCTTTGATTGTTCGTGAGGGAGGAG
AAATCCATGATTTAACCGATTTGAATGGAAAAATGCTTGGGTTTTGTACGGGTGGTAAAGAAGCTGCAAGTTTAAATAAG
CTATTAGCAAATGCTTCTATAGCAGTAAAAGGGTGTCTAAATGTTAATTGTGATTTGATTACCCCACTTAGAACTAAAAA
TATAGATGTTATTTATGGTGCTTACTGGAATATTGAAACTGAACATTTAAAAAGCCTGGGTATACGCACACGTTATTTTA
AGCTAACGGAACTTGGAATGCCCACTTATTATGAATTGATTGTTTTAGCTAAAACTAAAACAATTTATACAGAAGATGAA
TTTGTTCAATTGTTTAAAAAAGGATTACAAAAAAGTATTAACTATTCTAGATTACATCCAAACGAAGCTTTTGAAATCTA
TGCCCTTTATCAGCAAAATAAAAGTATACAGACACTTACGTGGGAAAGAGAAGCTTGGAAAAAAACCATTCCTGTTTTAG
CTGAGCAGCAAGAGGTTTCACCCATGATATGGAACACTTTTCAGGAGTGGTTAAGGATTAATCAATTATTATAA

Upstream 100 bases:

>100_bases
AAAATCATTTATCGATACTCTTATCTTTATCCTATTTTGTTGAAAAAAATTAGTTAAAAGATGCCTTTCTATTCAGATTA
TTATAAATATGAAAAATATC

Downstream 100 bases:

>100_bases
AATTGTTTGGTTGGAATTTTATGGAATTTGAAAAAAAATTAATTGAAGTTCAACAACAATTAAAAAAAGAAAAGATCAAT
GGTTGGCTGCTTTATGATTT

Product: hypothetical protein

Products: taurine [Cytoplasm]; ADP; phosphate [C]

Alternate protein names: NA

Number of amino acids: Translated: 557; Mature: 557

Protein sequence:

>557_residues
MIVTCTFLFILFVWEFFSYFNPNLIWVLPPPSQIFNQLIEKPDCFLFHTGVTLKEILGGFALAFSVAFPLAWIMDHFSIA
RNFLQPFFVIIQCIPMFTLAPIMIMWFGWSYIAIAIPTALMIFFPLTITLFQGLRSVPKELTDYFMINHATHWQIFCKLK
LPWSLPHLFSGLRLSAAIAGIAAIAGEWAGAQNGLGVLMVESRRDMDLATNFAALFCLTLLSYLIYSIILLIEYFILKKR
FFKILKAHFTYSRLTYSIVFVFFVGCGILMGCHRQASSKPPVRLVLDWLPNPNHIPFYVGIHKGFFQEHHINISIKKMQE
PGHATSYLLLDQCELALAYMPHTIRVEQKKGEVEPIGILIQEPLNALIVREGGEIHDLTDLNGKMLGFCTGGKEAASLNK
LLANASIAVKGCLNVNCDLITPLRTKNIDVIYGAYWNIETEHLKSLGIRTRYFKLTELGMPTYYELIVLAKTKTIYTEDE
FVQLFKKGLQKSINYSRLHPNEAFEIYALYQQNKSIQTLTWEREAWKKTIPVLAEQQEVSPMIWNTFQEWLRINQLL

Sequences:

>Translated_557_residues
MIVTCTFLFILFVWEFFSYFNPNLIWVLPPPSQIFNQLIEKPDCFLFHTGVTLKEILGGFALAFSVAFPLAWIMDHFSIA
RNFLQPFFVIIQCIPMFTLAPIMIMWFGWSYIAIAIPTALMIFFPLTITLFQGLRSVPKELTDYFMINHATHWQIFCKLK
LPWSLPHLFSGLRLSAAIAGIAAIAGEWAGAQNGLGVLMVESRRDMDLATNFAALFCLTLLSYLIYSIILLIEYFILKKR
FFKILKAHFTYSRLTYSIVFVFFVGCGILMGCHRQASSKPPVRLVLDWLPNPNHIPFYVGIHKGFFQEHHINISIKKMQE
PGHATSYLLLDQCELALAYMPHTIRVEQKKGEVEPIGILIQEPLNALIVREGGEIHDLTDLNGKMLGFCTGGKEAASLNK
LLANASIAVKGCLNVNCDLITPLRTKNIDVIYGAYWNIETEHLKSLGIRTRYFKLTELGMPTYYELIVLAKTKTIYTEDE
FVQLFKKGLQKSINYSRLHPNEAFEIYALYQQNKSIQTLTWEREAWKKTIPVLAEQQEVSPMIWNTFQEWLRINQLL
>Mature_557_residues
MIVTCTFLFILFVWEFFSYFNPNLIWVLPPPSQIFNQLIEKPDCFLFHTGVTLKEILGGFALAFSVAFPLAWIMDHFSIA
RNFLQPFFVIIQCIPMFTLAPIMIMWFGWSYIAIAIPTALMIFFPLTITLFQGLRSVPKELTDYFMINHATHWQIFCKLK
LPWSLPHLFSGLRLSAAIAGIAAIAGEWAGAQNGLGVLMVESRRDMDLATNFAALFCLTLLSYLIYSIILLIEYFILKKR
FFKILKAHFTYSRLTYSIVFVFFVGCGILMGCHRQASSKPPVRLVLDWLPNPNHIPFYVGIHKGFFQEHHINISIKKMQE
PGHATSYLLLDQCELALAYMPHTIRVEQKKGEVEPIGILIQEPLNALIVREGGEIHDLTDLNGKMLGFCTGGKEAASLNK
LLANASIAVKGCLNVNCDLITPLRTKNIDVIYGAYWNIETEHLKSLGIRTRYFKLTELGMPTYYELIVLAKTKTIYTEDE
FVQLFKKGLQKSINYSRLHPNEAFEIYALYQQNKSIQTLTWEREAWKKTIPVLAEQQEVSPMIWNTFQEWLRINQLL

Specific function: Probably involved in thiamine biosynthesis [H]

COG id: COG0600

COG function: function code P; ABC-type nitrate/sulfonate/bicarbonate transport system, permease component

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NMT1 family [H]

Homologues:

Organism=Escherichia coli, GI1786564, Length=191, Percent_Identity=27.2251308900524, Blast_Score=66, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015168 [H]

Pfam domain/function: PF09084 NMT1 [H]

EC number: NA

Molecular weight: Translated: 63971; Mature: 63971

Theoretical pI: Translated: 8.33; Mature: 8.33

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIVTCTFLFILFVWEFFSYFNPNLIWVLPPPSQIFNQLIEKPDCFLFHTGVTLKEILGGF
CEEHHHHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHCCCCEEEEECCCHHHHHHHHH
ALAFSVAFPLAWIMDHFSIARNFLQPFFVIIQCIPMFTLAPIMIMWFGWSYIAIAIPTAL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MIFFPLTITLFQGLRSVPKELTDYFMINHATHWQIFCKLKLPWSLPHLFSGLRLSAAIAG
HHHHHHHHHHHHHHHHHHHHHHHHHHEECCEEEEEEEEEECCCCCHHHHHHHHHHHHHHH
IAAIAGEWAGAQNGLGVLMVESRRDMDLATNFAALFCLTLLSYLIYSIILLIEYFILKKR
HHHHHHCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FFKILKAHFTYSRLTYSIVFVFFVGCGILMGCHRQASSKPPVRLVLDWLPNPNHIPFYVG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCCCCEEEEE
IHKGFFQEHHINISIKKMQEPGHATSYLLLDQCELALAYMPHTIRVEQKKGEVEPIGILI
ECCCCCHHCEEEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCEEEEECCCCCCCHHHHHH
QEPLNALIVREGGEIHDLTDLNGKMLGFCTGGKEAASLNKLLANASIAVKGCLNVNCDLI
HCCCCEEEEECCCCEECCCCCCCCEEEEECCCCHHHHHHHHHHCCCEEEEEEECCCCEEE
TPLRTKNIDVIYGAYWNIETEHLKSLGIRTRYFKLTELGMPTYYELIVLAKTKTIYTEDE
CCCCCCCEEEEEEEEECCCHHHHHHCCCCCEEEEEECCCCCCCEEEEEEEECCEEECHHH
FVQLFKKGLQKSINYSRLHPNEAFEIYALYQQNKSIQTLTWEREAWKKTIPVLAEQQEVS
HHHHHHHHHHHCCCCCCCCCCCCEEEEEEEECCCCEEEEEECHHHHHHHCCHHCCHHHCC
PMIWNTFQEWLRINQLL
HHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MIVTCTFLFILFVWEFFSYFNPNLIWVLPPPSQIFNQLIEKPDCFLFHTGVTLKEILGGF
CEEHHHHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHCCCCEEEEECCCHHHHHHHHH
ALAFSVAFPLAWIMDHFSIARNFLQPFFVIIQCIPMFTLAPIMIMWFGWSYIAIAIPTAL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MIFFPLTITLFQGLRSVPKELTDYFMINHATHWQIFCKLKLPWSLPHLFSGLRLSAAIAG
HHHHHHHHHHHHHHHHHHHHHHHHHHEECCEEEEEEEEEECCCCCHHHHHHHHHHHHHHH
IAAIAGEWAGAQNGLGVLMVESRRDMDLATNFAALFCLTLLSYLIYSIILLIEYFILKKR
HHHHHHCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FFKILKAHFTYSRLTYSIVFVFFVGCGILMGCHRQASSKPPVRLVLDWLPNPNHIPFYVG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCCCCEEEEE
IHKGFFQEHHINISIKKMQEPGHATSYLLLDQCELALAYMPHTIRVEQKKGEVEPIGILI
ECCCCCHHCEEEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCEEEEECCCCCCCHHHHHH
QEPLNALIVREGGEIHDLTDLNGKMLGFCTGGKEAASLNKLLANASIAVKGCLNVNCDLI
HCCCCEEEEECCCCEECCCCCCCCEEEEECCCCHHHHHHHHHHCCCEEEEEEECCCCEEE
TPLRTKNIDVIYGAYWNIETEHLKSLGIRTRYFKLTELGMPTYYELIVLAKTKTIYTEDE
CCCCCCCEEEEEEEEECCCHHHHHHCCCCCEEEEEECCCCCCCEEEEEEEECCEEECHHH
FVQLFKKGLQKSINYSRLHPNEAFEIYALYQQNKSIQTLTWEREAWKKTIPVLAEQQEVS
HHHHHHHHHHHCCCCCCCCCCCCEEEEEEEECCCCEEEEEECHHHHHHHCCHHCCHHHCC
PMIWNTFQEWLRINQLL
HHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: taurine [Periplasm]; ATP; H2O [C]

Specific reaction: taurine [Periplasm] + ATP + H2O = taurine [Cytoplasm] + ADP + phosphate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800; 10675023 [H]