Click here to switch to the map view.

The map label for this gene is tagD

Identifier: 45657412

GI number: 45657412

Start: 1901394

End: 1901870

Strand: Direct

Name: tagD

Synonym: LIC11539

Alternate gene names: 45657412

Gene position: 1901394-1901870 (Clockwise)

Preceding gene: 45657411

Following gene: 45657413

Centisome position: 44.45

GC content: 37.11

Gene sequence:

>477_bases
ATGGACTTAAAAAATCACGTCGTTTCCTGGCAAAACGTCGCGGCTTTTGCGGATCAGGTTCGAAAAAATAAAAAAATTGT
TTTTACGAACGGTTGTTTCGATTTAGTACATAAAGGTCACATAACGTATCTTTCTCAGGCAAGAGAGTTAGGTGATTTTC
TCTGGATAGGACTCAATTCGGATTCTTCTGTAAAACGTCTGAAAGGGGAACAAAGACCTTTAATTTGCGAAGAAGATCGA
GCGATTCTTCTTTCTAATTTGAGATTTGTGGATGCGGTTACGATTTTTTCTCAGGATACTCCTTTGGATCTAATTCGTTT
GATCAAACCTAAGATTCACGTAAAGGGAGGAGATTACAAAGTAGAAGAATTGCCTGAAACGAAAATAATCAGAGAATTAG
GAGGGGATGTTCAAATTTTACCCTTTGTCCCTGGAAAATCCACCTCTTCCATCATCGAAAAAATTTTAAAACTCTAA

Upstream 100 bases:

>100_bases
TGCGGCCGCTGGAGTCGTAGTTGGAAAGTTAGGCGCAGAAACTGTAACCCCGGGGGAATTAGAACTTTCTTTACAATCTA
TGGGGAGTTTTGAAAATTAA

Downstream 100 bases:

>100_bases
AATTAAATCTCCCTCATCTTTGTAATTGTGCTTTGATATGGGAATTACATATATCCTCGTTTTGTAAGAAAATGTTACGA
GACCTGATTTACAAATAGAA

Product: glycerol-3-phosphate cytidyltransferase

Products: diphosphate; CDPglycerol

Alternate protein names: D-beta-D-heptose 7-phosphate kinase; D-beta-D-heptose 7-phosphotransferase; D-beta-D-heptose 1-phosphate adenosyltransferase [H]

Number of amino acids: Translated: 158; Mature: 158

Protein sequence:

>158_residues
MDLKNHVVSWQNVAAFADQVRKNKKIVFTNGCFDLVHKGHITYLSQARELGDFLWIGLNSDSSVKRLKGEQRPLICEEDR
AILLSNLRFVDAVTIFSQDTPLDLIRLIKPKIHVKGGDYKVEELPETKIIRELGGDVQILPFVPGKSTSSIIEKILKL

Sequences:

>Translated_158_residues
MDLKNHVVSWQNVAAFADQVRKNKKIVFTNGCFDLVHKGHITYLSQARELGDFLWIGLNSDSSVKRLKGEQRPLICEEDR
AILLSNLRFVDAVTIFSQDTPLDLIRLIKPKIHVKGGDYKVEELPETKIIRELGGDVQILPFVPGKSTSSIIEKILKL
>Mature_158_residues
MDLKNHVVSWQNVAAFADQVRKNKKIVFTNGCFDLVHKGHITYLSQARELGDFLWIGLNSDSSVKRLKGEQRPLICEEDR
AILLSNLRFVDAVTIFSQDTPLDLIRLIKPKIHVKGGDYKVEELPETKIIRELGGDVQILPFVPGKSTSSIIEKILKL

Specific function: Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose [H]

COG id: COG2870

COG function: function code M; ADP-heptose synthase, bifunctional sugar kinase/adenylyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the cytidylyltransferase family [H]

Homologues:

Organism=Escherichia coli, GI1789432, Length=141, Percent_Identity=48.936170212766, Blast_Score=132, Evalue=8e-33,
Organism=Caenorhabditis elegans, GI115533408, Length=116, Percent_Identity=30.1724137931034, Blast_Score=64, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI193209647, Length=116, Percent_Identity=30.1724137931034, Blast_Score=64, Evalue=4e-11,
Organism=Drosophila melanogaster, GI19921220, Length=136, Percent_Identity=29.4117647058824, Blast_Score=66, Evalue=1e-11,
Organism=Drosophila melanogaster, GI45550973, Length=134, Percent_Identity=29.8507462686567, Blast_Score=65, Evalue=1e-11,
Organism=Drosophila melanogaster, GI45550975, Length=134, Percent_Identity=29.8507462686567, Blast_Score=65, Evalue=2e-11,
Organism=Drosophila melanogaster, GI45550974, Length=134, Percent_Identity=29.8507462686567, Blast_Score=65, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023030
- InterPro:   IPR011611
- InterPro:   IPR002173
- InterPro:   IPR004821
- InterPro:   IPR004820
- InterPro:   IPR011913
- InterPro:   IPR011914
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01467 CTP_transf_2; PF00294 PfkB [H]

EC number: 2.7.7.39

Molecular weight: Translated: 17880; Mature: 17880

Theoretical pI: Translated: 9.18; Mature: 9.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLKNHVVSWQNVAAFADQVRKNKKIVFTNGCFDLVHKGHITYLSQARELGDFLWIGLNS
CCCHHHHCCHHHHHHHHHHHHCCCCEEEECCHHHHHHCCCHHHHHHHHHCCCEEEEEECC
DSSVKRLKGEQRPLICEEDRAILLSNLRFVDAVTIFSQDTPLDLIRLIKPKIHVKGGDYK
CCHHHHHCCCCCCEEECCCCEEEHHCCHHHHEEEEECCCCCHHHHHHCCCEEEECCCCEE
VEELPETKIIRELGGDVQILPFVPGKSTSSIIEKILKL
HHHCCHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHCC
>Mature Secondary Structure
MDLKNHVVSWQNVAAFADQVRKNKKIVFTNGCFDLVHKGHITYLSQARELGDFLWIGLNS
CCCHHHHCCHHHHHHHHHHHHCCCCEEEECCHHHHHHCCCHHHHHHHHHCCCEEEEEECC
DSSVKRLKGEQRPLICEEDRAILLSNLRFVDAVTIFSQDTPLDLIRLIKPKIHVKGGDYK
CCHHHHHCCCCCCEEECCCCEEEHHCCHHHHEEEEECCCCCHHHHHHCCCEEEECCCCEE
VEELPETKIIRELGGDVQILPFVPGKSTSSIIEKILKL
HHHCCHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: CTP; sn-glycerol 3-phosphate

Specific reaction: CTP + sn-glycerol 3-phosphate = diphosphate + CDP-glycerol

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA