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The map label for this gene is rfaE2

Identifier: 45657411

GI number: 45657411

Start: 1900380

End: 1901393

Strand: Direct

Name: rfaE2

Synonym: LIC11538

Alternate gene names: 45657411

Gene position: 1900380-1901393 (Clockwise)

Preceding gene: 45657409

Following gene: 45657412

Centisome position: 44.43

GC content: 38.26

Gene sequence:

>1014_bases
TTGTATTATCTAAATAGAAATCGCTTTCAAACTTCAACAGCTAATCTTAAAAATTTAAAAGTGATTGTGATTGGAGATTT
CATCTTGGATGAATATCTTATCGGAGAAGTAAGTCGAATTTCTCCAGAAGCTCCAGTTCCAGTAGTCTGGGTTCGTACAG
AAAAGATTACTTTAGGTGGGGCGGGAAATGTGGTCAAAAATTTATCAAGTTTAGGGGTAAAGTCAGTTGTTCTTGGAAGA
ACTGGAAAAGACGAAAGGGCGAAAAATCTTGCCGGTCTTCTACACCATGAAAACACAGATAAGGATCAGAACTTTTTGAT
TGCATCCGAAGGTGTGCCAACGATTGTAAAAACAAGAGTGATAGCAGGGCATCAACAGGTTTGTAGGATTGATAAAGAAG
AATTAAAACCAATCAATTCAAACGAAGAAGACGAACTTCTCAGAGCTTTTTTAGAAAGAATCGATTCTGCGGACGCGGTG
ATTCTTTCTGACTACGATAAGGGAACTTTAACTCCTAGGATTATCAGCGAAGTTTCTAAAATCTGCGTGGATAAAAAAAA
GATCGTAACAGTTGATCCACAGGTGAGTCATTTTTTTCTATATAAAAGAGTGAGTATTCTGACTCCAAATCATCACGAAG
CAGGTAAGGCCATCGGAAGAAAATTAGAAAACGATTCTGAAATTTTAAATGCGGTGGAAGAAATTTCCGAAAAACTTTCT
TGTCCTTCTCTTATGATTACAAGAGGAGAAAAGGGGATGAGTTTATACCTTTCTTCTAATAAAGAAATATTTCATATTCC
GACGGTTGCAAAAGAAGTATTCGATGTTACCGGTGCCGGTGATACTGTTATCAGTACTTACACAGCCTATCACGCCGCTG
GGTTGAACGAATTAGAAGCAAGTATCGTTTCCAATGCGGCCGCTGGAGTCGTAGTTGGAAAGTTAGGCGCAGAAACTGTA
ACCCCGGGGGAATTAGAACTTTCTTTACAATCTATGGGGAGTTTTGAAAATTAA

Upstream 100 bases:

>100_bases
CCGGTAACGGAAAGATTGGGACAGTAGTGATTGACACAGGAAGCATACTATAACTGCTTATATAGAAACCGTAAATCAAA
ATCCCAAGGATCAGTAGAAT

Downstream 100 bases:

>100_bases
ATGGACTTAAAAAATCACGTCGTTTCCTGGCAAAACGTCGCGGCTTTTGCGGATCAGGTTCGAAAAAATAAAAAAATTGT
TTTTACGAACGGTTGTTTCG

Product: ADP-heptose synthase

Products: NA

Alternate protein names: D-beta-D-heptose 7-phosphate kinase; D-beta-D-heptose 7-phosphotransferase; D-beta-D-heptose 1-phosphate adenosyltransferase [H]

Number of amino acids: Translated: 337; Mature: 337

Protein sequence:

>337_residues
MYYLNRNRFQTSTANLKNLKVIVIGDFILDEYLIGEVSRISPEAPVPVVWVRTEKITLGGAGNVVKNLSSLGVKSVVLGR
TGKDERAKNLAGLLHHENTDKDQNFLIASEGVPTIVKTRVIAGHQQVCRIDKEELKPINSNEEDELLRAFLERIDSADAV
ILSDYDKGTLTPRIISEVSKICVDKKKIVTVDPQVSHFFLYKRVSILTPNHHEAGKAIGRKLENDSEILNAVEEISEKLS
CPSLMITRGEKGMSLYLSSNKEIFHIPTVAKEVFDVTGAGDTVISTYTAYHAAGLNELEASIVSNAAAGVVVGKLGAETV
TPGELELSLQSMGSFEN

Sequences:

>Translated_337_residues
MYYLNRNRFQTSTANLKNLKVIVIGDFILDEYLIGEVSRISPEAPVPVVWVRTEKITLGGAGNVVKNLSSLGVKSVVLGR
TGKDERAKNLAGLLHHENTDKDQNFLIASEGVPTIVKTRVIAGHQQVCRIDKEELKPINSNEEDELLRAFLERIDSADAV
ILSDYDKGTLTPRIISEVSKICVDKKKIVTVDPQVSHFFLYKRVSILTPNHHEAGKAIGRKLENDSEILNAVEEISEKLS
CPSLMITRGEKGMSLYLSSNKEIFHIPTVAKEVFDVTGAGDTVISTYTAYHAAGLNELEASIVSNAAAGVVVGKLGAETV
TPGELELSLQSMGSFEN
>Mature_337_residues
MYYLNRNRFQTSTANLKNLKVIVIGDFILDEYLIGEVSRISPEAPVPVVWVRTEKITLGGAGNVVKNLSSLGVKSVVLGR
TGKDERAKNLAGLLHHENTDKDQNFLIASEGVPTIVKTRVIAGHQQVCRIDKEELKPINSNEEDELLRAFLERIDSADAV
ILSDYDKGTLTPRIISEVSKICVDKKKIVTVDPQVSHFFLYKRVSILTPNHHEAGKAIGRKLENDSEILNAVEEISEKLS
CPSLMITRGEKGMSLYLSSNKEIFHIPTVAKEVFDVTGAGDTVISTYTAYHAAGLNELEASIVSNAAAGVVVGKLGAETV
TPGELELSLQSMGSFEN

Specific function: Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose [H]

COG id: COG2870

COG function: function code M; ADP-heptose synthase, bifunctional sugar kinase/adenylyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the cytidylyltransferase family [H]

Homologues:

Organism=Escherichia coli, GI1789432, Length=306, Percent_Identity=41.1764705882353, Blast_Score=196, Evalue=2e-51,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023030
- InterPro:   IPR011611
- InterPro:   IPR002173
- InterPro:   IPR004821
- InterPro:   IPR004820
- InterPro:   IPR011913
- InterPro:   IPR011914
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01467 CTP_transf_2; PF00294 PfkB [H]

EC number: 2.7.-.-

Molecular weight: Translated: 36831; Mature: 36831

Theoretical pI: Translated: 5.90; Mature: 5.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYYLNRNRFQTSTANLKNLKVIVIGDFILDEYLIGEVSRISPEAPVPVVWVRTEKITLGG
CEEECCCCCCCCCCCCCCEEEEEEEHHHHHHHHHHHHHHCCCCCCCCEEEEEEEEEEECC
AGNVVKNLSSLGVKSVVLGRTGKDERAKNLAGLLHHENTDKDQNFLIASEGVPTIVKTRV
CCHHHHHHHHCCHHEEEECCCCCHHHHHHHHHHHHCCCCCCCCCEEEECCCCCHHHHHHH
IAGHQQVCRIDKEELKPINSNEEDELLRAFLERIDSADAVILSDYDKGTLTPRIISEVSK
HHCCHHHHHCCHHHCCCCCCCCHHHHHHHHHHHCCCCCEEEEECCCCCCCCHHHHHHHHH
ICVDKKKIVTVDPQVSHFFLYKRVSILTPNHHEAGKAIGRKLENDSEILNAVEEISEKLS
HHCCCCEEEEECCCHHHHHHHHHHEEECCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHC
CPSLMITRGEKGMSLYLSSNKEIFHIPTVAKEVFDVTGAGDTVISTYTAYHAAGLNELEA
CCCEEEECCCCCEEEEEECCCCEEECCHHHHHHHHCCCCCCHHHHHHHHHHHCCHHHHHH
SIVSNAAAGVVVGKLGAETVTPGELELSLQSMGSFEN
HHHHCCCCCEEEECCCCCCCCCCCEEEEHHHCCCCCC
>Mature Secondary Structure
MYYLNRNRFQTSTANLKNLKVIVIGDFILDEYLIGEVSRISPEAPVPVVWVRTEKITLGG
CEEECCCCCCCCCCCCCCEEEEEEEHHHHHHHHHHHHHHCCCCCCCCEEEEEEEEEEECC
AGNVVKNLSSLGVKSVVLGRTGKDERAKNLAGLLHHENTDKDQNFLIASEGVPTIVKTRV
CCHHHHHHHHCCHHEEEECCCCCHHHHHHHHHHHHCCCCCCCCCEEEECCCCCHHHHHHH
IAGHQQVCRIDKEELKPINSNEEDELLRAFLERIDSADAVILSDYDKGTLTPRIISEVSK
HHCCHHHHHCCHHHCCCCCCCCHHHHHHHHHHHCCCCCEEEEECCCCCCCCHHHHHHHHH
ICVDKKKIVTVDPQVSHFFLYKRVSILTPNHHEAGKAIGRKLENDSEILNAVEEISEKLS
HHCCCCEEEEECCCHHHHHHHHHHEEECCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHC
CPSLMITRGEKGMSLYLSSNKEIFHIPTVAKEVFDVTGAGDTVISTYTAYHAAGLNELEA
CCCEEEECCCCCEEEEEECCCCEEECCHHHHHHHHCCCCCCHHHHHHHHHHHCCHHHHHH
SIVSNAAAGVVVGKLGAETVTPGELELSLQSMGSFEN
HHHHCCCCCEEEECCCCCCCCCCCEEEEHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA