| Definition | Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 chromosome chromosome I, complete sequence. |
|---|---|
| Accession | NC_005823 |
| Length | 4,277,185 |
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The map label for this gene is fkp
Identifier: 45657300
GI number: 45657300
Start: 1750898
End: 1751287
Strand: Direct
Name: fkp
Synonym: LIC11424
Alternate gene names: 45657300
Gene position: 1750898-1751287 (Clockwise)
Preceding gene: 45657299
Following gene: 45657301
Centisome position: 40.94
GC content: 40.26
Gene sequence:
>390_bases ATGAAATTTACACGTTTAATATTTGTCTTAGCTATTCTTTGTGCCGTAGTAGCTCCTACATTTGCAGAAGATTTAGTTAT CAAAGAAATTCGTATTGGAACTGGAAAAGAAGCTTTTTCGGGTTCGAATGTTACGGTTCATTATGTAGGCACATTAACGA ACGGCAAGAAGTTCGATAGTTCCAGAGACAGAAAAAACCCTTTTACCTTCAATTTGGGAGCGGGAGAGGTAATCAAAGGT TGGGACAGAGGGGTTCGAGGGATGAAAGAAGGTGGGATTCGTAAACTTACAATTCCTCCAGAATTAGGTTATGGTTCCAG AGGGGCCGGAGCTGCGATTCCTCCTAATTCTACTCTCATTTTTGAAGTTGAATTGTTGAAAGTGTACTGA
Upstream 100 bases:
>100_bases CCCTAAAGAATGGAGGATCATCCGGTAAGATTCACGGAAATCAATCAAAGACTGGAGGTTTTTCCGGGGCTGGGGTTAGA AGAACCGGAGGAAGAGGAAA
Downstream 100 bases:
>100_bases GTTTTTTTCTTTTGTAGTAAATTTTACCGAATTTTGACATAGGATTCGGTCCTCTTTCCAGTTCTAATCTATCTCAGAAA GGAGAAGCCTTAGATAGCTT
Product: peptidyl-prolyl cis-trans isomerase
Products: NA
Alternate protein names: Peptidyl-prolyl cis-trans isomerase; PPIase; Rotamase [H]
Number of amino acids: Translated: 129; Mature: 129
Protein sequence:
>129_residues MKFTRLIFVLAILCAVVAPTFAEDLVIKEIRIGTGKEAFSGSNVTVHYVGTLTNGKKFDSSRDRKNPFTFNLGAGEVIKG WDRGVRGMKEGGIRKLTIPPELGYGSRGAGAAIPPNSTLIFEVELLKVY
Sequences:
>Translated_129_residues MKFTRLIFVLAILCAVVAPTFAEDLVIKEIRIGTGKEAFSGSNVTVHYVGTLTNGKKFDSSRDRKNPFTFNLGAGEVIKG WDRGVRGMKEGGIRKLTIPPELGYGSRGAGAAIPPNSTLIFEVELLKVY >Mature_129_residues MKFTRLIFVLAILCAVVAPTFAEDLVIKEIRIGTGKEAFSGSNVTVHYVGTLTNGKKFDSSRDRKNPFTFNLGAGEVIKG WDRGVRGMKEGGIRKLTIPPELGYGSRGAGAAIPPNSTLIFEVELLKVY
Specific function: PPIases accelerate the folding of proteins [H]
COG id: COG0545
COG function: function code O; FKBP-type peptidyl-prolyl cis-trans isomerases 1
Gene ontology:
Cell location: Cytoplasm And Periplasmic Protein [C]
Metaboloic importance: Unknown [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 1 PPIase FKBP-type domain [H]
Homologues:
Organism=Homo sapiens, GI206725530, Length=136, Percent_Identity=47.0588235294118, Blast_Score=112, Evalue=1e-25, Organism=Homo sapiens, GI17149844, Length=136, Percent_Identity=47.0588235294118, Blast_Score=112, Evalue=1e-25, Organism=Homo sapiens, GI17149842, Length=136, Percent_Identity=47.0588235294118, Blast_Score=112, Evalue=1e-25, Organism=Homo sapiens, GI224809329, Length=97, Percent_Identity=56.701030927835, Blast_Score=109, Evalue=7e-25, Organism=Homo sapiens, GI224809327, Length=97, Percent_Identity=56.701030927835, Blast_Score=109, Evalue=7e-25, Organism=Homo sapiens, GI4758384, Length=97, Percent_Identity=56.701030927835, Blast_Score=109, Evalue=7e-25, Organism=Homo sapiens, GI224809331, Length=97, Percent_Identity=56.701030927835, Blast_Score=107, Evalue=3e-24, Organism=Homo sapiens, GI4503729, Length=103, Percent_Identity=54.3689320388349, Blast_Score=107, Evalue=4e-24, Organism=Homo sapiens, GI17149836, Length=88, Percent_Identity=55.6818181818182, Blast_Score=103, Evalue=4e-23, Organism=Homo sapiens, GI4503725, Length=88, Percent_Identity=55.6818181818182, Blast_Score=103, Evalue=4e-23, Organism=Homo sapiens, GI4758380, Length=88, Percent_Identity=54.5454545454545, Blast_Score=100, Evalue=4e-22, Organism=Homo sapiens, GI192448443, Length=109, Percent_Identity=45.8715596330275, Blast_Score=91, Evalue=2e-19, Organism=Homo sapiens, GI33469985, Length=90, Percent_Identity=45.5555555555556, Blast_Score=85, Evalue=2e-17, Organism=Homo sapiens, GI8923659, Length=134, Percent_Identity=39.5522388059701, Blast_Score=82, Evalue=8e-17, Organism=Homo sapiens, GI4503727, Length=96, Percent_Identity=42.7083333333333, Blast_Score=76, Evalue=9e-15, Organism=Homo sapiens, GI206725547, Length=99, Percent_Identity=42.4242424242424, Blast_Score=72, Evalue=1e-13, Organism=Homo sapiens, GI150010552, Length=113, Percent_Identity=36.283185840708, Blast_Score=72, Evalue=2e-13, Organism=Homo sapiens, GI31317231, Length=100, Percent_Identity=43, Blast_Score=69, Evalue=8e-13, Organism=Homo sapiens, GI206725544, Length=103, Percent_Identity=35.9223300970874, Blast_Score=64, Evalue=4e-11, Organism=Homo sapiens, GI146229346, Length=103, Percent_Identity=35.9223300970874, Blast_Score=63, Evalue=5e-11, Organism=Escherichia coli, GI87082390, Length=104, Percent_Identity=47.1153846153846, Blast_Score=83, Evalue=5e-18, Organism=Escherichia coli, GI1789745, Length=104, Percent_Identity=48.0769230769231, Blast_Score=82, Evalue=8e-18, Organism=Caenorhabditis elegans, GI17540882, Length=127, Percent_Identity=46.4566929133858, Blast_Score=114, Evalue=2e-26, Organism=Caenorhabditis elegans, GI71993519, Length=89, Percent_Identity=62.9213483146067, Blast_Score=110, Evalue=1e-25, Organism=Caenorhabditis elegans, GI17561782, Length=88, Percent_Identity=57.9545454545455, Blast_Score=103, Evalue=2e-23, Organism=Caenorhabditis elegans, GI17561778, Length=96, Percent_Identity=43.75, Blast_Score=81, Evalue=1e-16, Organism=Caenorhabditis elegans, GI71993555, Length=75, Percent_Identity=52, Blast_Score=77, Evalue=3e-15, Organism=Caenorhabditis elegans, GI17506169, Length=93, Percent_Identity=41.9354838709677, Blast_Score=72, Evalue=5e-14, Organism=Caenorhabditis elegans, GI17506167, Length=93, Percent_Identity=41.9354838709677, Blast_Score=72, Evalue=7e-14, Organism=Caenorhabditis elegans, GI17561780, Length=102, Percent_Identity=40.1960784313725, Blast_Score=72, Evalue=1e-13, Organism=Saccharomyces cerevisiae, GI6324194, Length=105, Percent_Identity=54.2857142857143, Blast_Score=106, Evalue=1e-24, Organism=Saccharomyces cerevisiae, GI6320727, Length=107, Percent_Identity=49.5327102803738, Blast_Score=98, Evalue=4e-22, Organism=Saccharomyces cerevisiae, GI6323566, Length=104, Percent_Identity=48.0769230769231, Blast_Score=88, Evalue=3e-19, Organism=Saccharomyces cerevisiae, GI6323482, Length=104, Percent_Identity=47.1153846153846, Blast_Score=85, Evalue=3e-18, Organism=Drosophila melanogaster, GI281363946, Length=132, Percent_Identity=48.4848484848485, Blast_Score=124, Evalue=1e-29, Organism=Drosophila melanogaster, GI17352457, Length=132, Percent_Identity=48.4848484848485, Blast_Score=124, Evalue=1e-29, Organism=Drosophila melanogaster, GI24655568, Length=89, Percent_Identity=60.6741573033708, Blast_Score=112, Evalue=7e-26, Organism=Drosophila melanogaster, GI24647110, Length=99, Percent_Identity=57.5757575757576, Blast_Score=106, Evalue=4e-24, Organism=Drosophila melanogaster, GI21356629, Length=132, Percent_Identity=50, Blast_Score=105, Evalue=7e-24, Organism=Drosophila melanogaster, GI24583150, Length=103, Percent_Identity=51.4563106796116, Blast_Score=98, Evalue=1e-21,
Paralogues:
None
Copy number: 340 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR001179 [H]
Pfam domain/function: PF00254 FKBP_C [H]
EC number: =5.2.1.8 [H]
Molecular weight: Translated: 14004; Mature: 14004
Theoretical pI: Translated: 10.26; Mature: 10.26
Prosite motif: PS50059 FKBP_PPIASE
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.8 %Cys (Translated Protein) 1.6 %Met (Translated Protein) 2.3 %Cys+Met (Translated Protein) 0.8 %Cys (Mature Protein) 1.6 %Met (Mature Protein) 2.3 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MKFTRLIFVLAILCAVVAPTFAEDLVIKEIRIGTGKEAFSGSNVTVHYVGTLTNGKKFDS CCHHHHHHHHHHHHHHHCCHHHHHHHHHEEECCCCCCCCCCCCEEEEEEEEECCCCCCCC SRDRKNPFTFNLGAGEVIKGWDRGVRGMKEGGIRKLTIPPELGYGSRGAGAAIPPNSTLI CCCCCCCEEEECCCCHHHHHHHHHCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCEEE FEVELLKVY EEEEEEEEC >Mature Secondary Structure MKFTRLIFVLAILCAVVAPTFAEDLVIKEIRIGTGKEAFSGSNVTVHYVGTLTNGKKFDS CCHHHHHHHHHHHHHHHCCHHHHHHHHHEEECCCCCCCCCCCCEEEEEEEEECCCCCCCC SRDRKNPFTFNLGAGEVIKGWDRGVRGMKEGGIRKLTIPPELGYGSRGAGAAIPPNSTLI CCCCCCCEEEECCCCHHHHHHHHHCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCEEE FEVELLKVY EEEEEEEEC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 10761919 [H]