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The map label for this gene is virA [H]

Identifier: 45657301

GI number: 45657301

Start: 1751396

End: 1752517

Strand: Direct

Name: virA [H]

Synonym: LIC11425

Alternate gene names: 45657301

Gene position: 1751396-1752517 (Clockwise)

Preceding gene: 45657300

Following gene: 45657302

Centisome position: 40.95

GC content: 35.65

Gene sequence:

>1122_bases
ATGCCTTATAATTTTTTTGAAAATTTCCCCTTACCGGCCTGTATTTTAGAACCGTCTCTTTTGATACAAAAAGTAAATTT
TGCATTTTGTAAAACCATAGGTTATTCAAAAGAAGAGCTAGAAGGAATTCTAAATTGGGACCAAATTTGTGAATTTAAAG
ATACAAAATTCCATTTTGCAGATCCACCTCTTTGGCCTTGTACAAATCTACCTAGCGAAAATCCTTCTCATTCTATCTTA
CTTTATACAAAGGATGGGACTAAAAAAGAATGTTCCGTTGCTTTTGCCTTTGATCGTGAAGAATTGAGGATCTTCGCCTA
TTTGGAAATTCCACAGGTTCTAAATAAACCAGTCGTAAAATTTGATTCTCTAAAATCTTCTGCAACAGAAAAGGATTGGG
AAAAACCAGACGTGGCTTGGGTTCAAAAAGAGAAATTAGACGCGATCGGAACTCTTTCCGCCGGGGTTGCGCATGAAATT
AACAATCCTCTAATGGGAGTGATCAACTACGCAGAAATGATGGTCAACGGTATCGAAAACGGAAATCCTCTTCGTAAATA
TGCAGGAATTATCTTACGGGAAGGAAATAGAATTTCAGAAATCGTAAAAGATATGCTTACATTTACTCGGATCGAAAAAG
AAGAGATCAAAATTCATAATATTAAATCTATTTTCGAATCCGCCTTTGGAGTGATTAAAACCTGTATCGATAAATCAAAA
ATTGAAACGGTTGTATCTGATCCGGAAACTCCCATTTTTGTGGCTTGTTCCGCCGGAAAACTGAGAAAGATATATTTTAA
TTTACTCACAAATGCAAAAGATGCGATCGAAAGTAATACCGATCCAAATCAAAAAAGAGTTTTGAGTGTTTCTTGGGAAA
AATTGAAAAAAGAAAATAAGGATTTTATACGTACCATCATAGAAGATACTGGAATAGGCATTCCAGAAGAAAACAGACAT
AAACTTTTTGATCCTTTTTACACTACAAAGGATATCGGAAAAGGAACCGGTTTAGGACTTACGGTTTCGTATAACTTAAC
TCGTGAAATGGGTGGAGAACTTTCTTTCGAAAGTGGGAACGGAGTGACTCGCTTTTATCTGGATCTTCCAGAATCGATTT
GA

Upstream 100 bases:

>100_bases
CTTTTGTAGTAAATTTTACCGAATTTTGACATAGGATTCGGTCCTCTTTCCAGTTCTAATCTATCTCAGAAAGGAGAAGC
CTTAGATAGCTTAGAATTGG

Downstream 100 bases:

>100_bases
AAGATCCTTGACTTTTTAGGAGGACGATCACATTCTAATAGACTCCTTTTAAACCACTCTATGACCGGTTCCAGGCGATC
AGAACAGAAAAGTTACGAGC

Product: histidine kinase sensor protein

Products: NA

Alternate protein names: WHR virA [H]

Number of amino acids: Translated: 373; Mature: 372

Protein sequence:

>373_residues
MPYNFFENFPLPACILEPSLLIQKVNFAFCKTIGYSKEELEGILNWDQICEFKDTKFHFADPPLWPCTNLPSENPSHSIL
LYTKDGTKKECSVAFAFDREELRIFAYLEIPQVLNKPVVKFDSLKSSATEKDWEKPDVAWVQKEKLDAIGTLSAGVAHEI
NNPLMGVINYAEMMVNGIENGNPLRKYAGIILREGNRISEIVKDMLTFTRIEKEEIKIHNIKSIFESAFGVIKTCIDKSK
IETVVSDPETPIFVACSAGKLRKIYFNLLTNAKDAIESNTDPNQKRVLSVSWEKLKKENKDFIRTIIEDTGIGIPEENRH
KLFDPFYTTKDIGKGTGLGLTVSYNLTREMGGELSFESGNGVTRFYLDLPESI

Sequences:

>Translated_373_residues
MPYNFFENFPLPACILEPSLLIQKVNFAFCKTIGYSKEELEGILNWDQICEFKDTKFHFADPPLWPCTNLPSENPSHSIL
LYTKDGTKKECSVAFAFDREELRIFAYLEIPQVLNKPVVKFDSLKSSATEKDWEKPDVAWVQKEKLDAIGTLSAGVAHEI
NNPLMGVINYAEMMVNGIENGNPLRKYAGIILREGNRISEIVKDMLTFTRIEKEEIKIHNIKSIFESAFGVIKTCIDKSK
IETVVSDPETPIFVACSAGKLRKIYFNLLTNAKDAIESNTDPNQKRVLSVSWEKLKKENKDFIRTIIEDTGIGIPEENRH
KLFDPFYTTKDIGKGTGLGLTVSYNLTREMGGELSFESGNGVTRFYLDLPESI
>Mature_372_residues
PYNFFENFPLPACILEPSLLIQKVNFAFCKTIGYSKEELEGILNWDQICEFKDTKFHFADPPLWPCTNLPSENPSHSILL
YTKDGTKKECSVAFAFDREELRIFAYLEIPQVLNKPVVKFDSLKSSATEKDWEKPDVAWVQKEKLDAIGTLSAGVAHEIN
NPLMGVINYAEMMVNGIENGNPLRKYAGIILREGNRISEIVKDMLTFTRIEKEEIKIHNIKSIFESAFGVIKTCIDKSKI
ETVVSDPETPIFVACSAGKLRKIYFNLLTNAKDAIESNTDPNQKRVLSVSWEKLKKENKDFIRTIIEDTGIGIPEENRHK
LFDPFYTTKDIGKGTGLGLTVSYNLTREMGGELSFESGNGVTRFYLDLPESI

Specific function: Activates virG, by phosphorylating it, in the presence of acetosyringone or hydroxysyringone [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1790436, Length=234, Percent_Identity=27.7777777777778, Blast_Score=98, Evalue=8e-22,
Organism=Escherichia coli, GI1788549, Length=234, Percent_Identity=27.7777777777778, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1789149, Length=216, Percent_Identity=31.4814814814815, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI48994928, Length=225, Percent_Identity=25.7777777777778, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI145693157, Length=231, Percent_Identity=25.5411255411255, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1790300, Length=235, Percent_Identity=25.531914893617, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI87081816, Length=233, Percent_Identity=26.6094420600858, Blast_Score=67, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 42273; Mature: 42142

Theoretical pI: Translated: 5.23; Mature: 5.23

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPYNFFENFPLPACILEPSLLIQKVNFAFCKTIGYSKEELEGILNWDQICEFKDTKFHFA
CCCCCCCCCCCCHHHHCHHHHHHHHHHHHHHHCCCCHHHHHHHCCHHHHHCCCCCEEEEC
DPPLWPCTNLPSENPSHSILLYTKDGTKKECSVAFAFDREELRIFAYLEIPQVLNKPVVK
CCCCCCCCCCCCCCCCCEEEEEECCCCCCCEEEEEEECCCCEEEEEEEECHHHHCCCCEE
FDSLKSSATEKDWEKPDVAWVQKEKLDAIGTLSAGVAHEINNPLMGVINYAEMMVNGIEN
HHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCC
GNPLRKYAGIILREGNRISEIVKDMLTFTRIEKEEIKIHNIKSIFESAFGVIKTCIDKSK
CCHHHHHHCEEEECCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IETVVSDPETPIFVACSAGKLRKIYFNLLTNAKDAIESNTDPNQKRVLSVSWEKLKKENK
HHHHHCCCCCCEEEEECCCCHHHHHHHHHHCHHHHHCCCCCCCHHEEEEEEHHHHHHCCH
DFIRTIIEDTGIGIPEENRHKLFDPFYTTKDIGKGTGLGLTVSYNLTREMGGELSFESGN
HHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHCCCCCCCEEEEEEEEHHHCCCEEEEECCC
GVTRFYLDLPESI
CEEEEEEECCCCC
>Mature Secondary Structure 
PYNFFENFPLPACILEPSLLIQKVNFAFCKTIGYSKEELEGILNWDQICEFKDTKFHFA
CCCCCCCCCCCHHHHCHHHHHHHHHHHHHHHCCCCHHHHHHHCCHHHHHCCCCCEEEEC
DPPLWPCTNLPSENPSHSILLYTKDGTKKECSVAFAFDREELRIFAYLEIPQVLNKPVVK
CCCCCCCCCCCCCCCCCEEEEEECCCCCCCEEEEEEECCCCEEEEEEEECHHHHCCCCEE
FDSLKSSATEKDWEKPDVAWVQKEKLDAIGTLSAGVAHEINNPLMGVINYAEMMVNGIEN
HHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCC
GNPLRKYAGIILREGNRISEIVKDMLTFTRIEKEEIKIHNIKSIFESAFGVIKTCIDKSK
CCHHHHHHCEEEECCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IETVVSDPETPIFVACSAGKLRKIYFNLLTNAKDAIESNTDPNQKRVLSVSWEKLKKENK
HHHHHCCCCCCEEEEECCCCHHHHHHHHHHCHHHHHCCCCCCCHHEEEEEEHHHHHHCCH
DFIRTIIEDTGIGIPEENRHKLFDPFYTTKDIGKGTGLGLTVSYNLTREMGGELSFESGN
HHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHCCCCCCCEEEEEEEEHHHCCCEEEEECCC
GVTRFYLDLPESI
CEEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 3595559 [H]