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The map label for this gene is ilvH

Identifier: 45657287

GI number: 45657287

Start: 1735548

End: 1736033

Strand: Direct

Name: ilvH

Synonym: LIC11410

Alternate gene names: 45657287

Gene position: 1735548-1736033 (Clockwise)

Preceding gene: 45657286

Following gene: 45657291

Centisome position: 40.58

GC content: 37.04

Gene sequence:

>486_bases
ATGAAACATATTCTAAAAATTCTGGTAAACAATCATCCTGGAGTTATGAGTCATGTATCCGGACTATTTACTCGCAGAAG
TTATAATATAGATTCGATTGCGGTAGGTGTTACCGTAAATCCAGAGATTTCAAGTATGGTGATCGTAGTTAAAGGAGACG
AAGCTACGGTGGATCAAGTCAAAAGACAGCTTTTGAAACTTCCAGATGTTTTAGAAGTGGAAGATCTTGCGTATCACGAT
TGTGTAAGTAGAGAATTAGTTTTACTTGTAGTAAAATTAACCGAGACGACTAGAGCGGAAATTCTTTCTGTATGTGAGGT
CTTTGAAGCAAAAATAGCGGACTTAACACATTCTTCTTTAACGATAGAATATTCGGGAAATTCCCGCAAAGTGAATGCGA
TCGTAGAAATTATGTCCAAATATGGGATCGAAGAAATTGTTCGTACAGGACAAATCGCGATTCGATACAGAAGTGTTGGA
TCTTAA

Upstream 100 bases:

>100_bases
TAATGATACCGGCGGAAGAAAAAGTATTTCCGATGATACCGGCGGGAAAGTCTCAAAAGGAAATGATCGAATTTAAGGAT
TTGGCCGGATTAAAAAAAGT

Downstream 100 bases:

>100_bases
ATTAAAGTTGTAAGCCATATCAAATCTAGAAATTAGAAAATATATTTGATATGGCTTTAAAGTATCAGATCAAGAGTCTG
TCTTAAATCCTGTCGAGCGA

Product: acetolactate synthase 3 regulatory subunit

Products: NA

Alternate protein names: Acetohydroxy-acid synthase small subunit; AHAS; ALS [H]

Number of amino acids: Translated: 161; Mature: 161

Protein sequence:

>161_residues
MKHILKILVNNHPGVMSHVSGLFTRRSYNIDSIAVGVTVNPEISSMVIVVKGDEATVDQVKRQLLKLPDVLEVEDLAYHD
CVSRELVLLVVKLTETTRAEILSVCEVFEAKIADLTHSSLTIEYSGNSRKVNAIVEIMSKYGIEEIVRTGQIAIRYRSVG
S

Sequences:

>Translated_161_residues
MKHILKILVNNHPGVMSHVSGLFTRRSYNIDSIAVGVTVNPEISSMVIVVKGDEATVDQVKRQLLKLPDVLEVEDLAYHD
CVSRELVLLVVKLTETTRAEILSVCEVFEAKIADLTHSSLTIEYSGNSRKVNAIVEIMSKYGIEEIVRTGQIAIRYRSVG
S
>Mature_161_residues
MKHILKILVNNHPGVMSHVSGLFTRRSYNIDSIAVGVTVNPEISSMVIVVKGDEATVDQVKRQLLKLPDVLEVEDLAYHD
CVSRELVLLVVKLTETTRAEILSVCEVFEAKIADLTHSSLTIEYSGNSRKVNAIVEIMSKYGIEEIVRTGQIAIRYRSVG
S

Specific function: Valine and isoleucine biosynthesis; first step. [C]

COG id: COG0440

COG function: function code E; Acetolactate synthase, small (regulatory) subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ACT domain [H]

Homologues:

Organism=Escherichia coli, GI1786266, Length=155, Percent_Identity=36.7741935483871, Blast_Score=104, Evalue=4e-24,
Organism=Saccharomyces cerevisiae, GI6319837, Length=202, Percent_Identity=27.2277227722772, Blast_Score=77, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004789
- InterPro:   IPR019455
- InterPro:   IPR002912 [H]

Pfam domain/function: PF01842 ACT; PF10369 ALS_ss_C [H]

EC number: =2.2.1.6 [H]

Molecular weight: Translated: 17865; Mature: 17865

Theoretical pI: Translated: 6.68; Mature: 6.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKHILKILVNNHPGVMSHVSGLFTRRSYNIDSIAVGVTVNPEISSMVIVVKGDEATVDQV
CHHHHEEHHCCCCCHHHHHHHHHHHCCCCCCEEEEEEEECCCCCEEEEEEECCCCHHHHH
KRQLLKLPDVLEVEDLAYHDCVSRELVLLVVKLTETTRAEILSVCEVFEAKIADLTHSSL
HHHHHCCCCCCCHHHHHHHHHHHHCEEEEEEECCCHHHHHHHHHHHHHHHHHHHCCCCEE
TIEYSGNSRKVNAIVEIMSKYGIEEIVRTGQIAIRYRSVGS
EEEECCCCCHHHHHHHHHHHCCHHHHHHCCEEEEEEECCCC
>Mature Secondary Structure
MKHILKILVNNHPGVMSHVSGLFTRRSYNIDSIAVGVTVNPEISSMVIVVKGDEATVDQV
CHHHHEEHHCCCCCHHHHHHHHHHHCCCCCCEEEEEEEECCCCCEEEEEEECCCCHHHHH
KRQLLKLPDVLEVEDLAYHDCVSRELVLLVVKLTETTRAEILSVCEVFEAKIADLTHSSL
HHHHHCCCCCCCHHHHHHHHHHHHCEEEEEEECCCHHHHHHHHHHHHHHHHHHHCCCCEE
TIEYSGNSRKVNAIVEIMSKYGIEEIVRTGQIAIRYRSVGS
EEEECCCCCHHHHHHHHHHHCCHHHHHHCCEEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231 [H]