| Definition | Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 chromosome chromosome I, complete sequence. |
|---|---|
| Accession | NC_005823 |
| Length | 4,277,185 |
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The map label for this gene is aphA [H]
Identifier: 45657084
GI number: 45657084
Start: 1478223
End: 1480895
Strand: Direct
Name: aphA [H]
Synonym: LIC11200
Alternate gene names: 45657084
Gene position: 1478223-1480895 (Clockwise)
Preceding gene: 45657083
Following gene: 45657085
Centisome position: 34.56
GC content: 35.8
Gene sequence:
>2673_bases ATGCAACTCACAGGAATAAAATCCTTAGAGGAATTCTCTGATAGTTTTTCCTCTTTCCAAGATCAAATATGCATACTCGA AGAACGCCCTTCTGGAAAAATCCGACTTTCTAAAGAATGTATTCGTTTTTGGCAGTTTAAAGGATTCAATCGGAAACCAG GAACGTTTCCTTCTTTTTTATTTCATCTTCACGGAAAGATCCGTAATTACGCGGATTTTACAGAAAAGATTCTACTAAAG CATATTCAAGACTCTGAATATTTTGATACACTTTTTACAGAAGATCATATTCTACGTTTTTTTTGGAAAGTAGTCTTTCG TAAAAGAGGGGTTTCTTATAGACTGTATACTTTTGAAATTTTGGCAAAAGAAGGTGATGACGAGGAGGAAGGGCCAGATG TAGAATCCATTTTTTATAAACTTCCAGAACCTGCGTTTTTATTTCATCCGTCTACCTTACGTTTTCTTGCGGTAAATGAC GCAGCGCTTTATTTATACGGATTTTCCAGAAAGGAATTTTCAGAAATGAATCTTTTAGACATTCGTCCGGAAGAAGATCG TGCTGACATGGAAATAGTCATTCAAAATTTTGCACAGGATTCAGGGATTCGATCCAGAGGAATTTGGAGACATTGGAGAA AAGATAAAAAATTTCTTTATGTGAAAATTACTACAAACCGGATTTCGTTTAGAGGTTCTTTTGCGGTACTCGTAATTTTA ACTGACGTTTCCGAGACGATAGAAACTTCCTATGCTTTAAAACAAAGTCGAGCCGAAAAACAGTCCATCATAGAAAGTAT GTCGGATCGATATTTTGCCCTTTCCAAAGATTGGAGATTTATTTCCGCAAACCAACAGTCCTTAATTACATTAGGAAAAA CTCAAGAAGAACTGATCGGCAGAAATATTTGGGATTTATTTTCAGGATCTACGTCTCGGTTTTTCAAAAACAGATATGAA CACGCGGTCCAAACCAAAAAACCGCTCGTTTTCGATTATAAGGTTCCAGAAACCGGGAATATAATGGAATACAGAGTTTT TCCTTTTGAAGAAGGAATCTCTGTGTTCTTCCAAGATATTACCGAAAAAAGAAGAAGAGAAACGGAACAAAATATACTCA AAGAAGTCACGTTAAAAATTCCAAACGCTTCGAGCGTAAAACAATCTTTCGAAATTCTTTTTGAAACGATTTGTAAGGGT ACTTCTTGGAGTTTTGCCCAAACTTGGAGATTTCAAAAAGGGGAAATCATTTTAGAAGAAAATTCTCCCTGGTATTCCAG CGACGCTAGTTTTTTACAATATAGGATGGCCTGTTTGGAAAATAAGTTTTCCCCAGGAGAAGGTACGATCGGGAAAGTTT TTTCTACTAAAAAAATTCGTTTTGTAAAGGACGTTCAAAAAGAAAAAGATTTTAAACGTACTAGCGCTGCGGTTCAAAAT GGGATTCGTTCTTGGATTGCAATTCCTTTACAAACGGGACACGAAACTTATGTTTTAGAATTTTTTACTCAGATAGAAAT AGATTTAGTAAATTCTTATATTCAAATGTTTGAATTGATCGCCGATCAAGTGGGTGTTTTATTCAAAAATAAGGAATCCG AAGAAGAAAAAGATCATTTTTTCAAATTGTCAGGGGATCTGTTTCAGATTTCTACTTTAGATGGACAGGTTATCGAACAG AATCAGGCCTGGGAGGAAATTTTAGGTTATACCCCGGAAGAGTTGGAAGAATTTGATCGTACAAATATAGTCCATCCGGA AGATCGCGATAAAATGTTGGACGCCGTCAGAAATGTTCGAAAATACAAAAAGAATGTTTCTTTCGCTCTTAGATATATAA CCAAACAAGGACAAACAAAAACCATTCTTTGGAAAACGATCGCTTCTCCAGAGCATGGGCTCGTTTATGCTTCTGGTAAG GACATTACTGAAATCCAGGATACTCAACTCAAACTAGAAAATCTGACAAGGGAACTAAAACGTTCAAACGCCGATTTAGA AGATTTTGCTTTTATCGCCTCTCACGATCTACAAGAACCTTTGAGAAAGATCATGGCGTTTGGAGATAGACTTTTAAAAA AGAATTCTAATCTAGATTCGGAGTCTATGGATTATCTACAGAGAATGTATTCTTCTGCGTGTAGATTATCCAATTTAATC GAAGGTCTTTTGTCTTATTCCAGAATTAAAAGTAAATCCAAACCGTTCCAGTTTTTAGATTTAAGCAGTGTTTTAAAAGA CGTTATCGGAGATTTGGAAATTTATATCAAAGAAAGAAATGCGAATGTGGTGGATTCTAAACTAGGTTATGCTTGGTGTG ATCCTTCTCAAATGGGAACGGTGTTTCAGAACCTGATCAAAAACGGAATTAAATTCAATCGAAGCGAAAGACCTGAAGTG ATTGTTCAATGTGTAGCACATCCAAGTGAACCAAACTGGATTCAAATTAGTTTTTCGGATAACGGAATCGGTTTTGATAA AAAACACGAGGATAAAATATTTACTATCTTTCAACGATTACACAACCGAGAGGATTATGAAGGAAACGGAATTGGTCTTG CTGTTTGTAAAAAAATTATAGAACTTCACGGAGGTAGAATTTACGCCAAGAGTACACTTCGGAAAGGTTCCACTTTTTAT TTAGAGTTTCCAGGTAAACTTGAGTCGGATTGA
Upstream 100 bases:
>100_bases AAAAACGAAATTAAGAAAAAACTAATTTCGTAAATTCTCATTTTTTAATTGAAATCATTTCGACAAAGAAGATAGAATTG CTCATCTTCGGCGAAATCTT
Downstream 100 bases:
>100_bases ATTATGAAAGCTGAAATTAAAAATCAAAAAACAATTCATATACTCGTTGCGGAGGATGATCCGGACGATCGTTTATTAAT GAAAGACGGTTTTCGAGAAA
Product: histidine kinase sensor protein
Products: NA
Alternate protein names: NA
Number of amino acids: Translated: 890; Mature: 890
Protein sequence:
>890_residues MQLTGIKSLEEFSDSFSSFQDQICILEERPSGKIRLSKECIRFWQFKGFNRKPGTFPSFLFHLHGKIRNYADFTEKILLK HIQDSEYFDTLFTEDHILRFFWKVVFRKRGVSYRLYTFEILAKEGDDEEEGPDVESIFYKLPEPAFLFHPSTLRFLAVND AALYLYGFSRKEFSEMNLLDIRPEEDRADMEIVIQNFAQDSGIRSRGIWRHWRKDKKFLYVKITTNRISFRGSFAVLVIL TDVSETIETSYALKQSRAEKQSIIESMSDRYFALSKDWRFISANQQSLITLGKTQEELIGRNIWDLFSGSTSRFFKNRYE HAVQTKKPLVFDYKVPETGNIMEYRVFPFEEGISVFFQDITEKRRRETEQNILKEVTLKIPNASSVKQSFEILFETICKG TSWSFAQTWRFQKGEIILEENSPWYSSDASFLQYRMACLENKFSPGEGTIGKVFSTKKIRFVKDVQKEKDFKRTSAAVQN GIRSWIAIPLQTGHETYVLEFFTQIEIDLVNSYIQMFELIADQVGVLFKNKESEEEKDHFFKLSGDLFQISTLDGQVIEQ NQAWEEILGYTPEELEEFDRTNIVHPEDRDKMLDAVRNVRKYKKNVSFALRYITKQGQTKTILWKTIASPEHGLVYASGK DITEIQDTQLKLENLTRELKRSNADLEDFAFIASHDLQEPLRKIMAFGDRLLKKNSNLDSESMDYLQRMYSSACRLSNLI EGLLSYSRIKSKSKPFQFLDLSSVLKDVIGDLEIYIKERNANVVDSKLGYAWCDPSQMGTVFQNLIKNGIKFNRSERPEV IVQCVAHPSEPNWIQISFSDNGIGFDKKHEDKIFTIFQRLHNREDYEGNGIGLAVCKKIIELHGGRIYAKSTLRKGSTFY LEFPGKLESD
Sequences:
>Translated_890_residues MQLTGIKSLEEFSDSFSSFQDQICILEERPSGKIRLSKECIRFWQFKGFNRKPGTFPSFLFHLHGKIRNYADFTEKILLK HIQDSEYFDTLFTEDHILRFFWKVVFRKRGVSYRLYTFEILAKEGDDEEEGPDVESIFYKLPEPAFLFHPSTLRFLAVND AALYLYGFSRKEFSEMNLLDIRPEEDRADMEIVIQNFAQDSGIRSRGIWRHWRKDKKFLYVKITTNRISFRGSFAVLVIL TDVSETIETSYALKQSRAEKQSIIESMSDRYFALSKDWRFISANQQSLITLGKTQEELIGRNIWDLFSGSTSRFFKNRYE HAVQTKKPLVFDYKVPETGNIMEYRVFPFEEGISVFFQDITEKRRRETEQNILKEVTLKIPNASSVKQSFEILFETICKG TSWSFAQTWRFQKGEIILEENSPWYSSDASFLQYRMACLENKFSPGEGTIGKVFSTKKIRFVKDVQKEKDFKRTSAAVQN GIRSWIAIPLQTGHETYVLEFFTQIEIDLVNSYIQMFELIADQVGVLFKNKESEEEKDHFFKLSGDLFQISTLDGQVIEQ NQAWEEILGYTPEELEEFDRTNIVHPEDRDKMLDAVRNVRKYKKNVSFALRYITKQGQTKTILWKTIASPEHGLVYASGK DITEIQDTQLKLENLTRELKRSNADLEDFAFIASHDLQEPLRKIMAFGDRLLKKNSNLDSESMDYLQRMYSSACRLSNLI EGLLSYSRIKSKSKPFQFLDLSSVLKDVIGDLEIYIKERNANVVDSKLGYAWCDPSQMGTVFQNLIKNGIKFNRSERPEV IVQCVAHPSEPNWIQISFSDNGIGFDKKHEDKIFTIFQRLHNREDYEGNGIGLAVCKKIIELHGGRIYAKSTLRKGSTFY LEFPGKLESD >Mature_890_residues MQLTGIKSLEEFSDSFSSFQDQICILEERPSGKIRLSKECIRFWQFKGFNRKPGTFPSFLFHLHGKIRNYADFTEKILLK HIQDSEYFDTLFTEDHILRFFWKVVFRKRGVSYRLYTFEILAKEGDDEEEGPDVESIFYKLPEPAFLFHPSTLRFLAVND AALYLYGFSRKEFSEMNLLDIRPEEDRADMEIVIQNFAQDSGIRSRGIWRHWRKDKKFLYVKITTNRISFRGSFAVLVIL TDVSETIETSYALKQSRAEKQSIIESMSDRYFALSKDWRFISANQQSLITLGKTQEELIGRNIWDLFSGSTSRFFKNRYE HAVQTKKPLVFDYKVPETGNIMEYRVFPFEEGISVFFQDITEKRRRETEQNILKEVTLKIPNASSVKQSFEILFETICKG TSWSFAQTWRFQKGEIILEENSPWYSSDASFLQYRMACLENKFSPGEGTIGKVFSTKKIRFVKDVQKEKDFKRTSAAVQN GIRSWIAIPLQTGHETYVLEFFTQIEIDLVNSYIQMFELIADQVGVLFKNKESEEEKDHFFKLSGDLFQISTLDGQVIEQ NQAWEEILGYTPEELEEFDRTNIVHPEDRDKMLDAVRNVRKYKKNVSFALRYITKQGQTKTILWKTIASPEHGLVYASGK DITEIQDTQLKLENLTRELKRSNADLEDFAFIASHDLQEPLRKIMAFGDRLLKKNSNLDSESMDYLQRMYSSACRLSNLI EGLLSYSRIKSKSKPFQFLDLSSVLKDVIGDLEIYIKERNANVVDSKLGYAWCDPSQMGTVFQNLIKNGIKFNRSERPEV IVQCVAHPSEPNWIQISFSDNGIGFDKKHEDKIFTIFQRLHNREDYEGNGIGLAVCKKIIELHGGRIYAKSTLRKGSTFY LEFPGKLESD
Specific function: Photoreceptor which exists in two forms that are reversibly interconvertible by light:the R form that absorbs maximally in the red region of the spectrum and the FR form that absorbs maximally in the far-red region [H]
COG id: COG0642
COG function: function code T; Signal transduction histidine kinase
Gene ontology:
Cell location: Integral Membrane Protein. Inner Membrane [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 1 histidine kinase domain [H]
Homologues:
Organism=Escherichia coli, GI48994928, Length=358, Percent_Identity=26.2569832402235, Blast_Score=89, Evalue=2e-18, Organism=Escherichia coli, GI1789149, Length=255, Percent_Identity=25.4901960784314, Blast_Score=74, Evalue=3e-14, Organism=Escherichia coli, GI1790436, Length=238, Percent_Identity=26.890756302521, Blast_Score=69, Evalue=9e-13, Organism=Escherichia coli, GI1786912, Length=213, Percent_Identity=25.8215962441315, Blast_Score=69, Evalue=2e-12, Organism=Escherichia coli, GI1788713, Length=272, Percent_Identity=22.7941176470588, Blast_Score=66, Evalue=1e-11, Organism=Escherichia coli, GI145693157, Length=250, Percent_Identity=25.2, Blast_Score=64, Evalue=6e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR003594 - InterPro: IPR003018 - InterPro: IPR013654 - InterPro: IPR016132 - InterPro: IPR001294 - InterPro: IPR013515 - InterPro: IPR003661 - InterPro: IPR005467 - InterPro: IPR009082 [H]
Pfam domain/function: PF01590 GAF; PF02518 HATPase_c; PF00512 HisKA; PF08446 PAS_2; PF00360 Phytochrome [H]
EC number: =2.7.13.3 [H]
Molecular weight: Translated: 103806; Mature: 103806
Theoretical pI: Translated: 6.96; Mature: 6.96
Prosite motif: PS50112 PAS ; PS50109 HIS_KIN
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.9 %Cys (Translated Protein) 1.3 %Met (Translated Protein) 2.2 %Cys+Met (Translated Protein) 0.9 %Cys (Mature Protein) 1.3 %Met (Mature Protein) 2.2 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MQLTGIKSLEEFSDSFSSFQDQICILEERPSGKIRLSKECIRFWQFKGFNRKPGTFPSFL CCCCCCHHHHHHHHHHHHHHCCEEEEECCCCCCEEECHHHHHHHHHCCCCCCCCCHHHHH FHLHGKIRNYADFTEKILLKHIQDSEYFDTLFTEDHILRFFWKVVFRKRGVSYRLYTFEI HHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEE LAKEGDDEEEGPDVESIFYKLPEPAFLFHPSTLRFLAVNDAALYLYGFSRKEFSEMNLLD EECCCCCCCCCCCHHHHHHHCCCCEEEECCCCEEEEEECCCEEEEEECCHHHHCCCCEEE IRPEEDRADMEIVIQNFAQDSGIRSRGIWRHWRKDKKFLYVKITTNRISFRGSFAVLVIL CCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHCCCCEEEEEEEEECEEEECCCEEEEEEE TDVSETIETSYALKQSRAEKQSIIESMSDRYFALSKDWRFISANQQSLITLGKTQEELIG ECCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCEEEECCCCCEEEECCCHHHHHC RNIWDLFSGSTSRFFKNRYEHAVQTKKPLVFDYKVPETGNIMEYRVFPFEEGISVFFQDI CHHHHHHCCCHHHHHHHHHHHHHHCCCCEEEEEECCCCCCEEEEEECCHHHHHHHHHHHH TEKRRRETEQNILKEVTLKIPNASSVKQSFEILFETICKGTSWSFAQTWRFQKGEIILEE HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCCCEEEEC NSPWYSSDASFLQYRMACLENKFSPGEGTIGKVFSTKKIRFVKDVQKEKDFKRTSAAVQN CCCCCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH GIRSWIAIPLQTGHETYVLEFFTQIEIDLVNSYIQMFELIADQVGVLFKNKESEEEKDHF HHHHHEEEEECCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHE FKLSGDLFQISTLDGQVIEQNQAWEEILGYTPEELEEFDRTNIVHPEDRDKMLDAVRNVR EEECCCEEEEEECCCHHHHCHHHHHHHHCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHH KYKKNVSFALRYITKQGQTKTILWKTIASPEHGLVYASGKDITEIQDTQLKLENLTRELK HHHHHHHHHHHHHHCCCCEEEEEEEEECCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHH RSNADLEDFAFIASHDLQEPLRKIMAFGDRLLKKNSNLDSESMDYLQRMYSSACRLSNLI HCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHH EGLLSYSRIKSKSKPFQFLDLSSVLKDVIGDLEIYIKERNANVVDSKLGYAWCDPSQMGT HHHHHHHHHHCCCCCCEEECHHHHHHHHHCCEEEEEEECCCCEECCCCCCEECCHHHHHH VFQNLIKNGIKFNRSERPEVIVQCVAHPSEPNWIQISFSDNGIGFDKKHEDKIFTIFQRL HHHHHHHCCCCCCCCCCHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHH HNREDYEGNGIGLAVCKKIIELHGGRIYAKSTLRKGSTFYLEFPGKLESD HCCCCCCCCCCHHHHHHHHHHHCCCEEEEEHHHCCCCEEEEECCCCCCCC >Mature Secondary Structure MQLTGIKSLEEFSDSFSSFQDQICILEERPSGKIRLSKECIRFWQFKGFNRKPGTFPSFL CCCCCCHHHHHHHHHHHHHHCCEEEEECCCCCCEEECHHHHHHHHHCCCCCCCCCHHHHH FHLHGKIRNYADFTEKILLKHIQDSEYFDTLFTEDHILRFFWKVVFRKRGVSYRLYTFEI HHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEE LAKEGDDEEEGPDVESIFYKLPEPAFLFHPSTLRFLAVNDAALYLYGFSRKEFSEMNLLD EECCCCCCCCCCCHHHHHHHCCCCEEEECCCCEEEEEECCCEEEEEECCHHHHCCCCEEE IRPEEDRADMEIVIQNFAQDSGIRSRGIWRHWRKDKKFLYVKITTNRISFRGSFAVLVIL CCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHCCCCEEEEEEEEECEEEECCCEEEEEEE TDVSETIETSYALKQSRAEKQSIIESMSDRYFALSKDWRFISANQQSLITLGKTQEELIG ECCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCEEEECCCCCEEEECCCHHHHHC RNIWDLFSGSTSRFFKNRYEHAVQTKKPLVFDYKVPETGNIMEYRVFPFEEGISVFFQDI CHHHHHHCCCHHHHHHHHHHHHHHCCCCEEEEEECCCCCCEEEEEECCHHHHHHHHHHHH TEKRRRETEQNILKEVTLKIPNASSVKQSFEILFETICKGTSWSFAQTWRFQKGEIILEE HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCCCEEEEC NSPWYSSDASFLQYRMACLENKFSPGEGTIGKVFSTKKIRFVKDVQKEKDFKRTSAAVQN CCCCCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH GIRSWIAIPLQTGHETYVLEFFTQIEIDLVNSYIQMFELIADQVGVLFKNKESEEEKDHF HHHHHEEEEECCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHE FKLSGDLFQISTLDGQVIEQNQAWEEILGYTPEELEEFDRTNIVHPEDRDKMLDAVRNVR EEECCCEEEEEECCCHHHHCHHHHHHHHCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHH KYKKNVSFALRYITKQGQTKTILWKTIASPEHGLVYASGKDITEIQDTQLKLENLTRELK HHHHHHHHHHHHHHCCCCEEEEEEEEECCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHH RSNADLEDFAFIASHDLQEPLRKIMAFGDRLLKKNSNLDSESMDYLQRMYSSACRLSNLI HCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHH EGLLSYSRIKSKSKPFQFLDLSSVLKDVIGDLEIYIKERNANVVDSKLGYAWCDPSQMGT HHHHHHHHHHCCCCCCEEECHHHHHHHHHCCEEEEEEECCCCEECCCCCCEECCHHHHHH VFQNLIKNGIKFNRSERPEVIVQCVAHPSEPNWIQISFSDNGIGFDKKHEDKIFTIFQRL HHHHHHHCCCCCCCCCCHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHH HNREDYEGNGIGLAVCKKIIELHGGRIYAKSTLRKGSTFYLEFPGKLESD HCCCCCCCCCCHHHHHHHHHHHCCCEEEEEHHHCCCCEEEEECCCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 6.0
TargetDB status: NA
Availability: NA
References: 11759840 [H]