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The map label for this gene is ychK [C]

Identifier: 45657083

GI number: 45657083

Start: 1475885

End: 1478155

Strand: Direct

Name: ychK [C]

Synonym: LIC11199

Alternate gene names: 45657083

Gene position: 1475885-1478155 (Clockwise)

Preceding gene: 45657082

Following gene: 45657084

Centisome position: 34.51

GC content: 35.49

Gene sequence:

>2271_bases
ATGGATCAATTTTCTTCCAAAGCGAAACATCTAAAACGATTGAGGTATTTTTATTCTAAAACGTCTTCTGAATTTCCTAC
ATGGAGAAATACAAAGGAAGAAGAAATCGTAGCAAAACACCTAAACCTCATACAATGGAATTCTGATATTTTGTCTTTGA
ATGTTCTTCCTGGTTCTTTGTGTCTAGTACTCTCCGAAAAGTTAGAGGAGACTTTACTCAATACAAAAGAAAAAGATCTG
GTTCTTAGAGAATTATTTCCTGGAGATTATTTTTTATTTCAACCAGATAAAATTTTACACTCTGGAATTTCAGAAATTCT
TTATATACTTCCAGATGAATTGAATCGGATCATTTCTAAACTTCCAAATTGGAAAAAATGGATTGAGGATTTAAATCAGA
AAAATCATCTTTTTCACGTTTCTAAGCTCAGACCTTCTAAAAAAGAACTGATGTCTTTTTTATCTTCCGTTGAACTTTTA
TTTCGTTTAGACAAGTCCACTCTTTCTAAGTTAGAATCCAGGATGGAATGGCTCGTAATTCCAGGAGGAGAGGTCTTGCT
CAAACAAGGGGATTCCGGCGATTCTATGTATATCTTGGTATCTGGTAGATTGTCTTGGACGGTACGTTCCGAAGATGAGG
AAATTTTAGCGGAAGGAGAACTCGGAAAAGGAGATATATTAGGAGAAATGTCCTTACTCAGCGGAGATAAAAGGTCCGCA
ACCGTAATCGCTTTAAGGACTAGTCAAGTTGTACGGATTTCCAGAGAAGATTTTCGTAAATGTTTTGCTAATTCTCCGGA
AGCTCTTTTTCAAATTACCGGAACCATCGCTCATCGATTGGGAACAGAAAGAAATCAGGTTTATCGAAAATCTAAATCCG
TCAAAACCGTTTCCGTTTTTCCTTTAAATTTTCAAGAAAATCCGGATGAATTCTATCGTTCACTTCAAAACGGTCTTAAA
AATTTTGGAAAAACAATATTAGTAGATTATAATTCTTTTAAAAATAGAGAGAAGTCTTTAAAAAAAAGAGATACGTATCG
GATCGGGGATTTAGTAAATTGGTTTTACGATCTAGAAAAATATTATGATAAACTTATATTCAAAACGGATATACAGAATC
CTGGTTGGAGAGAAACTTGTTTTCGTCAATCAGATCGTATTTTAGTTTTGATCGATCCAATTTTACCTTTTTCATCTTAC
TCCGAAGAAATAAATTCCATGTTACCCGAAACGATCCAGAAGGAACTGGTGTTTTTGATCGATTCTGACTTTATGGATTG
GAAAAAGATAGAATCGATTTTAAAAAAATTTCCTTCGATTTCTCATTCTATCGTTCGCAGAAGACTGGATGTAGATTTTG
GAAGATTGTCTAGACGACTCACCGGTAAAAGTATTGGAGTTGCACTTTCTGGAGGAGGTGCCAAAGGGTTTGCACATCTA
GGTCTTTTAAAATGTTTCGAAGAAAATGAGATTCCCGTGGATATGATTTCCGGAACGAGTGCGGGCGCGATTATGGGTGG
TTTGTTCGCGATGGGACTGGACTCTTCTGATATTTTACCTCTGATACGAAATTTTTGGTTGGACCGTAATTTACTCGGAG
ATTTTACGTTTCCGTTTGTATCTTTAGTTAGAGGAAAAAGATATTCTCAAGCGATTCATGAATTTTTTAAAGACAGAAGT
ATAGAAACTCTTCCGATTCCTTTTTATGCGATCGCTTGTAACTTAACCAAGGCGGAAAGAAAAGTTTTTGACAGAGGGTT
ATTGTGGAAGGCGGTTCGGTCTAGTACTTCTATTCCTGGGATTTTTCCTCCTTTTGCAGAAAGAGGGGAATTGTTTGTAG
ATGGTGGATTATTAGATAATCTTCCGGGTTCCATTTTAAAAGAAAGGGGCGCTGGAATTTTGATTTCAGTCGATTTAGGT
GGAGGAGGACAAATCGATAAGGATGAAATGTATCATAATTTACTTGGGCCTCACTATCTAGGAGAAGCCCCTTCCTTTTT
TAATCTTTTATTTCATCATCTAAAACGAAAAACTTTAAAAACCAAGTATACCGGATTTGCAGAAATTATGATGCGTTCTT
TGATGTTGTCCAGTAAAAACAATCAAAACCGCACTCGAAATGACTCAGATTTATACATAGAGTTGCCGGTAGGTGGATAT
TCCACTTTTGATTGGGATCAATTTCAGAAATTATACGAGATAGGATACGAAACCGGAAGAAAAAAAATTCATATTTGGAA
AAACGAAATTAAGAAAAAACTAATTTCGTAA

Upstream 100 bases:

>100_bases
TGATTGGATAGGTGTTTCTAAAAGTTAAAAAATAAAAACCTTGTTGTAGTGTGACGTGAAAATCTAGAATCGCTGAAAAA
TGAAACGTCTATTAAAGGAT

Downstream 100 bases:

>100_bases
ATTCTCATTTTTTAATTGAAATCATTTCGACAAAGAAGATAGAATTGCTCATCTTCGGCGAAATCTTATGCAACTCACAG
GAATAAAATCCTTAGAGGAA

Product: cyclic nucleotide binding patatin-like phospholipase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 756; Mature: 756

Protein sequence:

>756_residues
MDQFSSKAKHLKRLRYFYSKTSSEFPTWRNTKEEEIVAKHLNLIQWNSDILSLNVLPGSLCLVLSEKLEETLLNTKEKDL
VLRELFPGDYFLFQPDKILHSGISEILYILPDELNRIISKLPNWKKWIEDLNQKNHLFHVSKLRPSKKELMSFLSSVELL
FRLDKSTLSKLESRMEWLVIPGGEVLLKQGDSGDSMYILVSGRLSWTVRSEDEEILAEGELGKGDILGEMSLLSGDKRSA
TVIALRTSQVVRISREDFRKCFANSPEALFQITGTIAHRLGTERNQVYRKSKSVKTVSVFPLNFQENPDEFYRSLQNGLK
NFGKTILVDYNSFKNREKSLKKRDTYRIGDLVNWFYDLEKYYDKLIFKTDIQNPGWRETCFRQSDRILVLIDPILPFSSY
SEEINSMLPETIQKELVFLIDSDFMDWKKIESILKKFPSISHSIVRRRLDVDFGRLSRRLTGKSIGVALSGGGAKGFAHL
GLLKCFEENEIPVDMISGTSAGAIMGGLFAMGLDSSDILPLIRNFWLDRNLLGDFTFPFVSLVRGKRYSQAIHEFFKDRS
IETLPIPFYAIACNLTKAERKVFDRGLLWKAVRSSTSIPGIFPPFAERGELFVDGGLLDNLPGSILKERGAGILISVDLG
GGGQIDKDEMYHNLLGPHYLGEAPSFFNLLFHHLKRKTLKTKYTGFAEIMMRSLMLSSKNNQNRTRNDSDLYIELPVGGY
STFDWDQFQKLYEIGYETGRKKIHIWKNEIKKKLIS

Sequences:

>Translated_756_residues
MDQFSSKAKHLKRLRYFYSKTSSEFPTWRNTKEEEIVAKHLNLIQWNSDILSLNVLPGSLCLVLSEKLEETLLNTKEKDL
VLRELFPGDYFLFQPDKILHSGISEILYILPDELNRIISKLPNWKKWIEDLNQKNHLFHVSKLRPSKKELMSFLSSVELL
FRLDKSTLSKLESRMEWLVIPGGEVLLKQGDSGDSMYILVSGRLSWTVRSEDEEILAEGELGKGDILGEMSLLSGDKRSA
TVIALRTSQVVRISREDFRKCFANSPEALFQITGTIAHRLGTERNQVYRKSKSVKTVSVFPLNFQENPDEFYRSLQNGLK
NFGKTILVDYNSFKNREKSLKKRDTYRIGDLVNWFYDLEKYYDKLIFKTDIQNPGWRETCFRQSDRILVLIDPILPFSSY
SEEINSMLPETIQKELVFLIDSDFMDWKKIESILKKFPSISHSIVRRRLDVDFGRLSRRLTGKSIGVALSGGGAKGFAHL
GLLKCFEENEIPVDMISGTSAGAIMGGLFAMGLDSSDILPLIRNFWLDRNLLGDFTFPFVSLVRGKRYSQAIHEFFKDRS
IETLPIPFYAIACNLTKAERKVFDRGLLWKAVRSSTSIPGIFPPFAERGELFVDGGLLDNLPGSILKERGAGILISVDLG
GGGQIDKDEMYHNLLGPHYLGEAPSFFNLLFHHLKRKTLKTKYTGFAEIMMRSLMLSSKNNQNRTRNDSDLYIELPVGGY
STFDWDQFQKLYEIGYETGRKKIHIWKNEIKKKLIS
>Mature_756_residues
MDQFSSKAKHLKRLRYFYSKTSSEFPTWRNTKEEEIVAKHLNLIQWNSDILSLNVLPGSLCLVLSEKLEETLLNTKEKDL
VLRELFPGDYFLFQPDKILHSGISEILYILPDELNRIISKLPNWKKWIEDLNQKNHLFHVSKLRPSKKELMSFLSSVELL
FRLDKSTLSKLESRMEWLVIPGGEVLLKQGDSGDSMYILVSGRLSWTVRSEDEEILAEGELGKGDILGEMSLLSGDKRSA
TVIALRTSQVVRISREDFRKCFANSPEALFQITGTIAHRLGTERNQVYRKSKSVKTVSVFPLNFQENPDEFYRSLQNGLK
NFGKTILVDYNSFKNREKSLKKRDTYRIGDLVNWFYDLEKYYDKLIFKTDIQNPGWRETCFRQSDRILVLIDPILPFSSY
SEEINSMLPETIQKELVFLIDSDFMDWKKIESILKKFPSISHSIVRRRLDVDFGRLSRRLTGKSIGVALSGGGAKGFAHL
GLLKCFEENEIPVDMISGTSAGAIMGGLFAMGLDSSDILPLIRNFWLDRNLLGDFTFPFVSLVRGKRYSQAIHEFFKDRS
IETLPIPFYAIACNLTKAERKVFDRGLLWKAVRSSTSIPGIFPPFAERGELFVDGGLLDNLPGSILKERGAGILISVDLG
GGGQIDKDEMYHNLLGPHYLGEAPSFFNLLFHHLKRKTLKTKYTGFAEIMMRSLMLSSKNNQNRTRNDSDLYIELPVGGY
STFDWDQFQKLYEIGYETGRKKIHIWKNEIKKKLIS

Specific function: Unknown

COG id: COG1752

COG function: function code R; Predicted esterase of the alpha-beta hydrolase superfamily

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 patatin domain [H]

Homologues:

Organism=Homo sapiens, GI148727335, Length=673, Percent_Identity=27.1916790490342, Blast_Score=248, Evalue=2e-65,
Organism=Homo sapiens, GI148727290, Length=673, Percent_Identity=27.1916790490342, Blast_Score=247, Evalue=3e-65,
Organism=Homo sapiens, GI260656039, Length=682, Percent_Identity=24.9266862170088, Blast_Score=231, Evalue=1e-60,
Organism=Homo sapiens, GI260656041, Length=683, Percent_Identity=24.8901903367496, Blast_Score=231, Evalue=2e-60,
Organism=Homo sapiens, GI116256487, Length=683, Percent_Identity=24.8901903367496, Blast_Score=231, Evalue=2e-60,
Organism=Homo sapiens, GI260656043, Length=684, Percent_Identity=25.1461988304094, Blast_Score=231, Evalue=2e-60,
Organism=Homo sapiens, GI260656037, Length=685, Percent_Identity=25.1094890510949, Blast_Score=230, Evalue=3e-60,
Organism=Escherichia coli, GI226510936, Length=290, Percent_Identity=28.9655172413793, Blast_Score=105, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI193204778, Length=637, Percent_Identity=27.1585557299843, Blast_Score=186, Evalue=4e-47,
Organism=Caenorhabditis elegans, GI71997289, Length=697, Percent_Identity=26.1119081779053, Blast_Score=179, Evalue=4e-45,
Organism=Caenorhabditis elegans, GI71997299, Length=697, Percent_Identity=26.1119081779053, Blast_Score=179, Evalue=5e-45,
Organism=Saccharomyces cerevisiae, GI6323581, Length=364, Percent_Identity=31.043956043956, Blast_Score=179, Evalue=1e-45,
Organism=Drosophila melanogaster, GI281376913, Length=624, Percent_Identity=27.2435897435897, Blast_Score=209, Evalue=6e-54,
Organism=Drosophila melanogaster, GI28571388, Length=624, Percent_Identity=27.4038461538462, Blast_Score=208, Evalue=1e-53,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016035
- InterPro:   IPR018490
- InterPro:   IPR000595
- InterPro:   IPR001423
- InterPro:   IPR002641
- InterPro:   IPR014710 [H]

Pfam domain/function: PF00027 cNMP_binding; PF01734 Patatin [H]

EC number: NA

Molecular weight: Translated: 86810; Mature: 86810

Theoretical pI: Translated: 9.45; Mature: 9.45

Prosite motif: PS00889 CNMP_BINDING_2 ; PS50042 CNMP_BINDING_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDQFSSKAKHLKRLRYFYSKTSSEFPTWRNTKEEEIVAKHLNLIQWNSDILSLNVLPGSL
CCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHEEECCCEEEEEECCHHH
CLVLSEKLEETLLNTKEKDLVLRELFPGDYFLFQPDKILHSGISEILYILPDELNRIISK
HHHHHHHHHHHHHCCCHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHHHCCHHHHHHHHH
LPNWKKWIEDLNQKNHLFHVSKLRPSKKELMSFLSSVELLFRLDKSTLSKLESRMEWLVI
CCCHHHHHHHHCCCCCEEEEHHCCCCHHHHHHHHHHHHHHHHHCHHHHHHHHHCCCEEEE
PGGEVLLKQGDSGDSMYILVSGRLSWTVRSEDEEILAEGELGKGDILGEMSLLSGDKRSA
CCCEEEEECCCCCCEEEEEEECCEEEEEECCCHHHHHCCCCCCCCHHCCHHHHCCCCCCE
TVIALRTSQVVRISREDFRKCFANSPEALFQITGTIAHRLGTERNQVYRKSKSVKTVSVF
EEEEEECCHHHHHCHHHHHHHHCCCCHHHHHHHHHHHHHHCCHHHHHHHHHCCCEEEEEE
PLNFQENPDEFYRSLQNGLKNFGKTILVDYNSFKNREKSLKKRDTYRIGDLVNWFYDLEK
EECCCCCHHHHHHHHHHHHHHCCCEEEEECHHHCCHHHHHHHHCCHHHHHHHHHHHHHHH
YYDKLIFKTDIQNPGWRETCFRQSDRILVLIDPILPFSSYSEEINSMLPETIQKELVFLI
HHHHHEEEECCCCCCHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHEEEE
DSDFMDWKKIESILKKFPSISHSIVRRRLDVDFGRLSRRLTGKSIGVALSGGGAKGFAHL
CCCCCCHHHHHHHHHHCCCHHHHHHHHHHCCCHHHHHHHHCCCEEEEEEECCCCCHHHHH
GLLKCFEENEIPVDMISGTSAGAIMGGLFAMGLDSSDILPLIRNFWLDRNLLGDFTFPFV
HHHHHHCCCCCCEEEECCCCHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCHHCCHHHHHH
SLVRGKRYSQAIHEFFKDRSIETLPIPFYAIACNLTKAERKVFDRGLLWKAVRSSTSIPG
HHHHCCHHHHHHHHHHHCCCCCEECCCCEEEEECCCHHHHHHHHHHHHHHHHHCCCCCCC
IFPPFAERGELFVDGGLLDNLPGSILKERGAGILISVDLGGGGQIDKDEMYHNLLGPHYL
CCCCCCCCCCEEECCCCCCCCCHHHHHHCCCEEEEEEECCCCCCCCHHHHHHHHCCCHHC
GEAPSFFNLLFHHLKRKTLKTKYTGFAEIMMRSLMLSSKNNQNRTRNDSDLYIELPVGGY
CCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCC
STFDWDQFQKLYEIGYETGRKKIHIWKNEIKKKLIS
CCCCHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHCC
>Mature Secondary Structure
MDQFSSKAKHLKRLRYFYSKTSSEFPTWRNTKEEEIVAKHLNLIQWNSDILSLNVLPGSL
CCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHEEECCCEEEEEECCHHH
CLVLSEKLEETLLNTKEKDLVLRELFPGDYFLFQPDKILHSGISEILYILPDELNRIISK
HHHHHHHHHHHHHCCCHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHHHCCHHHHHHHHH
LPNWKKWIEDLNQKNHLFHVSKLRPSKKELMSFLSSVELLFRLDKSTLSKLESRMEWLVI
CCCHHHHHHHHCCCCCEEEEHHCCCCHHHHHHHHHHHHHHHHHCHHHHHHHHHCCCEEEE
PGGEVLLKQGDSGDSMYILVSGRLSWTVRSEDEEILAEGELGKGDILGEMSLLSGDKRSA
CCCEEEEECCCCCCEEEEEEECCEEEEEECCCHHHHHCCCCCCCCHHCCHHHHCCCCCCE
TVIALRTSQVVRISREDFRKCFANSPEALFQITGTIAHRLGTERNQVYRKSKSVKTVSVF
EEEEEECCHHHHHCHHHHHHHHCCCCHHHHHHHHHHHHHHCCHHHHHHHHHCCCEEEEEE
PLNFQENPDEFYRSLQNGLKNFGKTILVDYNSFKNREKSLKKRDTYRIGDLVNWFYDLEK
EECCCCCHHHHHHHHHHHHHHCCCEEEEECHHHCCHHHHHHHHCCHHHHHHHHHHHHHHH
YYDKLIFKTDIQNPGWRETCFRQSDRILVLIDPILPFSSYSEEINSMLPETIQKELVFLI
HHHHHEEEECCCCCCHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHEEEE
DSDFMDWKKIESILKKFPSISHSIVRRRLDVDFGRLSRRLTGKSIGVALSGGGAKGFAHL
CCCCCCHHHHHHHHHHCCCHHHHHHHHHHCCCHHHHHHHHCCCEEEEEEECCCCCHHHHH
GLLKCFEENEIPVDMISGTSAGAIMGGLFAMGLDSSDILPLIRNFWLDRNLLGDFTFPFV
HHHHHHCCCCCCEEEECCCCHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCHHCCHHHHHH
SLVRGKRYSQAIHEFFKDRSIETLPIPFYAIACNLTKAERKVFDRGLLWKAVRSSTSIPG
HHHHCCHHHHHHHHHHHCCCCCEECCCCEEEEECCCHHHHHHHHHHHHHHHHHCCCCCCC
IFPPFAERGELFVDGGLLDNLPGSILKERGAGILISVDLGGGGQIDKDEMYHNLLGPHYL
CCCCCCCCCCEEECCCCCCCCCHHHHHHCCCEEEEEEECCCCCCCCHHHHHHHHCCCHHC
GEAPSFFNLLFHHLKRKTLKTKYTGFAEIMMRSLMLSSKNNQNRTRNDSDLYIELPVGGY
CCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCC
STFDWDQFQKLYEIGYETGRKKIHIWKNEIKKKLIS
CCCCHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]