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The map label for this gene is 45656663

Identifier: 45656663

GI number: 45656663

Start: 934737

End: 936410

Strand: Direct

Name: 45656663

Synonym: LIC10769

Alternate gene names: NA

Gene position: 934737-936410 (Clockwise)

Preceding gene: 45656662

Following gene: 45656664

Centisome position: 21.85

GC content: 32.92

Gene sequence:

>1674_bases
ATGAAATGCTTAAAAGACGTCATGGTTTATCAAACGTATAATTTAGAACTATTAGAAAAATATAATTTTGTTTTTTCTAG
ATTTTTAAGTTATAAAGATCGATTTTTGAATTTGTATTCTAGGTTTTATTTTTTACCAAATAGATTGTTTAATTTTTTTC
GAAAAAGATTTTTGTTTAAAAGAAAGTCTTTCAATCTGCGGATGGGGTCCGATCTGAAAAGAATCGGTTTAAAAATAAAA
AATTACTATAGTAGAATATTCTATTATTCTATTTTACTTTTTATTTTTGCGACTTCTTTTTTAGAAGCTGCTCCCGGAGA
TTTTGTAAAAGACGTAAAAATTCCTCCCCTCACTTTTGAATTTCCAGAAGTGAAAGTTTTTGGTGTTGGAAAAGGAACGG
AGGTTTATTTTTTACCGGGAGAAGAATTCCCTCTCAGAAATTTAGAAATTCATATTTATGCAGGAGTTTTGTACAACCCG
AATCTTCCTCCCGAAGTTCCGGAACTTTTTGTTCAAGCTTGGAAACACGGAGGAGTTCCTTCAGCGCCAGGAAGTAAGTT
TATAGAAACTTTAGAAGGTTACGGAGCCAAAATTGATACAGACGTAAATTCCGAAAAAATTATATTCACGATTTCTTATC
TTTCTAGATTCGAAAAAGAAGTAGTTCCTCTGATTCGTGAATTTATTACCTCTCCGTTATTAAACGAAGAAGGTTTTGCG
GTTGCAAAACTCAACTTAGAGGAATCGATCAAAAGAAGAAACGATAAGATTTCCGATATTGCTTATCGTAAAACCGCAGA
ACTTGTCTATAAAGGAACCGTTTTAGGTAAAAGTGTTGAGTTGGATTCTCTTGCAAAAATCAACTCTAAGGATATTAAAG
AATACTTTGATAAAGCCGTTTCTACTTCTAAAAGAATCGTTCTACTTACGGGAGATTTACAAAAAGAAGAAGCAGAACTT
TTGATCGCTTCTATTTTACCTTTGAGAGAAAATTTTCGTAAGGAAACTTCAGTAAAAATCGATACACAAATTTTAAAGAA
AAATTTGGATTCTCTTTCCTTTCAAGTTTTAGGTGTGGATAAAGAAGCGACTCAAAGTGTAGTGATGATGACCGGAATTC
TTCCTGCACATAGAGATCCTGATTTTTATGCAATTCAGTTGGCGAATTATATCATCGGAGGTGGAGGTTTTAGTTCTTAT
TTGATGCAAAAGATTCGTTCTGATCGAGGACTTGCTTATTCTTCAGGTAGTTCTACTCATTTTGAGAAGGATTATGGAGT
GGTCTATTTTACTACTCAGACAAAAACTTCTACGACTAAAGAAGTCTACGATCTGATGCGTGAGATCCTAAGTGAAGAAA
CGATTTCTAAAATTACAGAAAAGGAACTGGAATCTGCAAAACAATCTATCGTCAATCGGTTTATCTTTCAATTTGTAGAT
AAGATGGGAATTCTTCATAACTTTCTTCGGTTTCAAGAACATGGTATGCCAAACGATTATTTAAAAACGTATCGAGATAA
AATTCAAGCAGTTACGTTAGGCGATCTTAAAAGAGTAGGAAAAAAATATTTTGTAAGCTCTTCTGTTAAAACGATTTTGA
CCGGTCCAAAAAACATTACAAAAGGTTTAAATGAATCCGTAAAACACATTACGCCAGAAGAAAGGATTCCTTAG

Upstream 100 bases:

>100_bases
ACTCCAGAGGACGTACAAAGAGTAGCAAAAAAATATTTTGTACCCGAAAATAGAACAATCGCGGAACTGAATCCTCCCGC
AAAAGGAGCAGGTAACTAAG

Downstream 100 bases:

>100_bases
TGTATTGTAAATTTCAACATAAACAGTATCAATTCGAAGGGATTTCGGAGGGAGGTATTCGTACTTCCTTGTATCTTCCT
TCCTTAAGTTTGATGTTTGA

Product: processing metalloprotease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 557; Mature: 557

Protein sequence:

>557_residues
MKCLKDVMVYQTYNLELLEKYNFVFSRFLSYKDRFLNLYSRFYFLPNRLFNFFRKRFLFKRKSFNLRMGSDLKRIGLKIK
NYYSRIFYYSILLFIFATSFLEAAPGDFVKDVKIPPLTFEFPEVKVFGVGKGTEVYFLPGEEFPLRNLEIHIYAGVLYNP
NLPPEVPELFVQAWKHGGVPSAPGSKFIETLEGYGAKIDTDVNSEKIIFTISYLSRFEKEVVPLIREFITSPLLNEEGFA
VAKLNLEESIKRRNDKISDIAYRKTAELVYKGTVLGKSVELDSLAKINSKDIKEYFDKAVSTSKRIVLLTGDLQKEEAEL
LIASILPLRENFRKETSVKIDTQILKKNLDSLSFQVLGVDKEATQSVVMMTGILPAHRDPDFYAIQLANYIIGGGGFSSY
LMQKIRSDRGLAYSSGSSTHFEKDYGVVYFTTQTKTSTTKEVYDLMREILSEETISKITEKELESAKQSIVNRFIFQFVD
KMGILHNFLRFQEHGMPNDYLKTYRDKIQAVTLGDLKRVGKKYFVSSSVKTILTGPKNITKGLNESVKHITPEERIP

Sequences:

>Translated_557_residues
MKCLKDVMVYQTYNLELLEKYNFVFSRFLSYKDRFLNLYSRFYFLPNRLFNFFRKRFLFKRKSFNLRMGSDLKRIGLKIK
NYYSRIFYYSILLFIFATSFLEAAPGDFVKDVKIPPLTFEFPEVKVFGVGKGTEVYFLPGEEFPLRNLEIHIYAGVLYNP
NLPPEVPELFVQAWKHGGVPSAPGSKFIETLEGYGAKIDTDVNSEKIIFTISYLSRFEKEVVPLIREFITSPLLNEEGFA
VAKLNLEESIKRRNDKISDIAYRKTAELVYKGTVLGKSVELDSLAKINSKDIKEYFDKAVSTSKRIVLLTGDLQKEEAEL
LIASILPLRENFRKETSVKIDTQILKKNLDSLSFQVLGVDKEATQSVVMMTGILPAHRDPDFYAIQLANYIIGGGGFSSY
LMQKIRSDRGLAYSSGSSTHFEKDYGVVYFTTQTKTSTTKEVYDLMREILSEETISKITEKELESAKQSIVNRFIFQFVD
KMGILHNFLRFQEHGMPNDYLKTYRDKIQAVTLGDLKRVGKKYFVSSSVKTILTGPKNITKGLNESVKHITPEERIP
>Mature_557_residues
MKCLKDVMVYQTYNLELLEKYNFVFSRFLSYKDRFLNLYSRFYFLPNRLFNFFRKRFLFKRKSFNLRMGSDLKRIGLKIK
NYYSRIFYYSILLFIFATSFLEAAPGDFVKDVKIPPLTFEFPEVKVFGVGKGTEVYFLPGEEFPLRNLEIHIYAGVLYNP
NLPPEVPELFVQAWKHGGVPSAPGSKFIETLEGYGAKIDTDVNSEKIIFTISYLSRFEKEVVPLIREFITSPLLNEEGFA
VAKLNLEESIKRRNDKISDIAYRKTAELVYKGTVLGKSVELDSLAKINSKDIKEYFDKAVSTSKRIVLLTGDLQKEEAEL
LIASILPLRENFRKETSVKIDTQILKKNLDSLSFQVLGVDKEATQSVVMMTGILPAHRDPDFYAIQLANYIIGGGGFSSY
LMQKIRSDRGLAYSSGSSTHFEKDYGVVYFTTQTKTSTTKEVYDLMREILSEETISKITEKELESAKQSIVNRFIFQFVD
KMGILHNFLRFQEHGMPNDYLKTYRDKIQAVTLGDLKRVGKKYFVSSSVKTILTGPKNITKGLNESVKHITPEERIP

Specific function: Unknown

COG id: COG0612

COG function: function code R; Predicted Zn-dependent peptidases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M16 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011249
- InterPro:   IPR011237
- InterPro:   IPR007863 [H]

Pfam domain/function: PF05193 Peptidase_M16_C [H]

EC number: NA

Molecular weight: Translated: 64110; Mature: 64110

Theoretical pI: Translated: 9.71; Mature: 9.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKCLKDVMVYQTYNLELLEKYNFVFSRFLSYKDRFLNLYSRFYFLPNRLFNFFRKRFLFK
CCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RKSFNLRMGSDLKRIGLKIKNYYSRIFYYSILLFIFATSFLEAAPGDFVKDVKIPPLTFE
HCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCCCCCEEE
FPEVKVFGVGKGTEVYFLPGEEFPLRNLEIHIYAGVLYNPNLPPEVPELFVQAWKHGGVP
CCCEEEEECCCCCEEEEECCCCCCCCCEEEEEEEEEEECCCCCCHHHHHHHHHHHCCCCC
SAPGSKFIETLEGYGAKIDTDVNSEKIIFTISYLSRFEKEVVPLIREFITSPLLNEEGFA
CCCHHHHHHHHHCCCCEEECCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHCCCCCCCCCE
VAKLNLEESIKRRNDKISDIAYRKTAELVYKGTVLGKSVELDSLAKINSKDIKEYFDKAV
EEEECHHHHHHHCCCCHHHHHHHHHHHHHEECEECCCCCCHHHHHHCCHHHHHHHHHHHH
STSKRIVLLTGDLQKEEAELLIASILPLRENFRKETSVKIDTQILKKNLDSLSFQVLGVD
CCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCEEEEEECC
KEATQSVVMMTGILPAHRDPDFYAIQLANYIIGGGGFSSYLMQKIRSDRGLAYSSGSSTH
HHHHHHHHHHHCCCCCCCCCCEEEEEEEHHHCCCCCHHHHHHHHHHHCCCCEECCCCCCC
FEKDYGVVYFTTQTKTSTTKEVYDLMREILSEETISKITEKELESAKQSIVNRFIFQFVD
CCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KMGILHNFLRFQEHGMPNDYLKTYRDKIQAVTLGDLKRVGKKYFVSSSVKTILTGPKNIT
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHEEHHHHHHHHHHHHHHHHCHHHHHCCCHHHH
KGLNESVKHITPEERIP
HHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MKCLKDVMVYQTYNLELLEKYNFVFSRFLSYKDRFLNLYSRFYFLPNRLFNFFRKRFLFK
CCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RKSFNLRMGSDLKRIGLKIKNYYSRIFYYSILLFIFATSFLEAAPGDFVKDVKIPPLTFE
HCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCCCCCEEE
FPEVKVFGVGKGTEVYFLPGEEFPLRNLEIHIYAGVLYNPNLPPEVPELFVQAWKHGGVP
CCCEEEEECCCCCEEEEECCCCCCCCCEEEEEEEEEEECCCCCCHHHHHHHHHHHCCCCC
SAPGSKFIETLEGYGAKIDTDVNSEKIIFTISYLSRFEKEVVPLIREFITSPLLNEEGFA
CCCHHHHHHHHHCCCCEEECCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHCCCCCCCCCE
VAKLNLEESIKRRNDKISDIAYRKTAELVYKGTVLGKSVELDSLAKINSKDIKEYFDKAV
EEEECHHHHHHHCCCCHHHHHHHHHHHHHEECEECCCCCCHHHHHHCCHHHHHHHHHHHH
STSKRIVLLTGDLQKEEAELLIASILPLRENFRKETSVKIDTQILKKNLDSLSFQVLGVD
CCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCEEEEEECC
KEATQSVVMMTGILPAHRDPDFYAIQLANYIIGGGGFSSYLMQKIRSDRGLAYSSGSSTH
HHHHHHHHHHHCCCCCCCCCCEEEEEEEHHHCCCCCHHHHHHHHHHHCCCCEECCCCCCC
FEKDYGVVYFTTQTKTSTTKEVYDLMREILSEETISKITEKELESAKQSIVNRFIFQFVD
CCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KMGILHNFLRFQEHGMPNDYLKTYRDKIQAVTLGDLKRVGKKYFVSSSVKTILTGPKNIT
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHEEHHHHHHHHHHHHHHHHCHHHHHCCCHHHH
KGLNESVKHITPEERIP
HHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9163424 [H]