Click here to switch to the map view.

The map label for this gene is 45656662

Identifier: 45656662

GI number: 45656662

Start: 933107

End: 934735

Strand: Direct

Name: 45656662

Synonym: LIC10768

Alternate gene names: NA

Gene position: 933107-934735 (Clockwise)

Preceding gene: 45656659

Following gene: 45656663

Centisome position: 21.82

GC content: 36.34

Gene sequence:

>1629_bases
ATGTGTTTTATACTAGGGATTCTTAAACTCTTTATAGTTTGTTTTAAAGTTCAAATTTTCCATCACAAAAAAAGCAGCAA
GGTTCTTATAATTTTAGGAATCTACCTTTGTATTTCAAATGTTTCTGTTTATGCGGACACTGCGATCTTTTCCGGTTTGA
AAAAATCTTTAGAAGAAAAGACCAGAACCTTTCAAATGGAAAACGGACTGAATGTTTTGATGATGAAACGGGAAGATTCT
CCCACCATCGCCGTCTATACTAAATTTTTAGTTGGTTCTGCCGACGAAACTCCAGAGATAGCTGGTACGGCTCATCTTTT
AGAGCATATGCTTTTTAAGGGAACTAAAAACATAGGAACCACAAACTATGAAAAGGAAAAACCTTACTTAGAACAGATTG
CCGTTTGGGGAAAAAGGTTGGATACCCTAAGGCTGAAAGAACTGGAAATGAAAGAAAAAGGAGAAGAACCTTCGGATGAA
TTTAAGAATCAAATTGAAACTTTGAAAAAAAGGTTTTATTCTCTTTTGGAACTACATCGTAAATTCGTAATTTCTAATGA
AGACAATTATATTTATTCTAAAAACGGAGGAGTAGGATTTAACGCATATACTTCGAACGACGTTACGAACTATCAGATTC
TTCTTCCTGCAAATCGTTTAGAAATTTGGGCCAAGTTGGAATCGGATCGATTGAAAAATCCTATATTAAGAGAATATTAT
ACAGAAAGGGACGTGGTCCTGGAAGAAAGAAGGATGCGTGTCGAAAACAGAGGTCTTGGGATTTTAAGGGAAAAATATTT
AGATGCAGCGTTTCCAGAAGGACATCCGTATCGTATGCCCGTAATCGGCTATGAAAAGAATTTAGGTTTTTTAGATTTGG
AAAAAACGAAAACGTTTTTTAAAAACTACTATGACCCGCAAAGAATGGTGATCGCGATAGTTGGTTCTTTGGATTTTGAT
AAAACGGAAAAAATACTACGTAACTATTTTGGAGATTTAAAAAAAGGAAGTCTTCAACCCTTGAAGAAAACAACTCAGGC
GGGATTTAACGGATCTAAATTTGTTTCCGTGGTTCATCCGAGTACTCCTTCTAAAATCATTGGTTTTCATAAACCCGCGT
TTCCTCATCCTGACGACGCCGTTTTTAGCATAATCGATACTTTGCTCGCCGAAGGAGAATCTGGAAGACTTTATAAAAAA
CTAATATTAGAAAAACAAGTCGCACAAGGAGTGTATTGTTGGAACGGAGATCCTGGAGATAGATTTTCTAATCTGTTTTC
TATCTACATTACAAACAATCAAAACGCGGATCAGAAAAAAGTGGAAAATCTAGTCCAAGAAGAATTGGATAAGTTAAAAA
CGGAACTGATTACTTCGGAAGAATTATTTAGAATCAAAAATCAAATCTTAGGTGGATACTTGCGCGCCTTGGACGACAAC
GGAAAACTTGCAGACGTCCTTTCGCTCTATCAACTGTTATACGGAGATTGGAGAGAACTTTTAAGAGGTTATGAGGAATT
AGATACAGTCACTCCAGAGGACGTACAAAGAGTAGCAAAAAAATATTTTGTACCCGAAAATAGAACAATCGCGGAACTGA
ATCCTCCCGCAAAAGGAGCAGGTAACTAA

Upstream 100 bases:

>100_bases
TCGCCGCATAAGACAAACGTATTTGAATCCATCGGAAAAGGAAGCAGGATTTTCCGGGAACTTTCTGGACACCAGGCCTT
AAAGAGGAAAGACTGTAGCT

Downstream 100 bases:

>100_bases
GATGAAATGCTTAAAAGACGTCATGGTTTATCAAACGTATAATTTAGAACTATTAGAAAAATATAATTTTGTTTTTTCTA
GATTTTTAAGTTATAAAGAT

Product: metalloprotease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 542; Mature: 542

Protein sequence:

>542_residues
MCFILGILKLFIVCFKVQIFHHKKSSKVLIILGIYLCISNVSVYADTAIFSGLKKSLEEKTRTFQMENGLNVLMMKREDS
PTIAVYTKFLVGSADETPEIAGTAHLLEHMLFKGTKNIGTTNYEKEKPYLEQIAVWGKRLDTLRLKELEMKEKGEEPSDE
FKNQIETLKKRFYSLLELHRKFVISNEDNYIYSKNGGVGFNAYTSNDVTNYQILLPANRLEIWAKLESDRLKNPILREYY
TERDVVLEERRMRVENRGLGILREKYLDAAFPEGHPYRMPVIGYEKNLGFLDLEKTKTFFKNYYDPQRMVIAIVGSLDFD
KTEKILRNYFGDLKKGSLQPLKKTTQAGFNGSKFVSVVHPSTPSKIIGFHKPAFPHPDDAVFSIIDTLLAEGESGRLYKK
LILEKQVAQGVYCWNGDPGDRFSNLFSIYITNNQNADQKKVENLVQEELDKLKTELITSEELFRIKNQILGGYLRALDDN
GKLADVLSLYQLLYGDWRELLRGYEELDTVTPEDVQRVAKKYFVPENRTIAELNPPAKGAGN

Sequences:

>Translated_542_residues
MCFILGILKLFIVCFKVQIFHHKKSSKVLIILGIYLCISNVSVYADTAIFSGLKKSLEEKTRTFQMENGLNVLMMKREDS
PTIAVYTKFLVGSADETPEIAGTAHLLEHMLFKGTKNIGTTNYEKEKPYLEQIAVWGKRLDTLRLKELEMKEKGEEPSDE
FKNQIETLKKRFYSLLELHRKFVISNEDNYIYSKNGGVGFNAYTSNDVTNYQILLPANRLEIWAKLESDRLKNPILREYY
TERDVVLEERRMRVENRGLGILREKYLDAAFPEGHPYRMPVIGYEKNLGFLDLEKTKTFFKNYYDPQRMVIAIVGSLDFD
KTEKILRNYFGDLKKGSLQPLKKTTQAGFNGSKFVSVVHPSTPSKIIGFHKPAFPHPDDAVFSIIDTLLAEGESGRLYKK
LILEKQVAQGVYCWNGDPGDRFSNLFSIYITNNQNADQKKVENLVQEELDKLKTELITSEELFRIKNQILGGYLRALDDN
GKLADVLSLYQLLYGDWRELLRGYEELDTVTPEDVQRVAKKYFVPENRTIAELNPPAKGAGN
>Mature_542_residues
MCFILGILKLFIVCFKVQIFHHKKSSKVLIILGIYLCISNVSVYADTAIFSGLKKSLEEKTRTFQMENGLNVLMMKREDS
PTIAVYTKFLVGSADETPEIAGTAHLLEHMLFKGTKNIGTTNYEKEKPYLEQIAVWGKRLDTLRLKELEMKEKGEEPSDE
FKNQIETLKKRFYSLLELHRKFVISNEDNYIYSKNGGVGFNAYTSNDVTNYQILLPANRLEIWAKLESDRLKNPILREYY
TERDVVLEERRMRVENRGLGILREKYLDAAFPEGHPYRMPVIGYEKNLGFLDLEKTKTFFKNYYDPQRMVIAIVGSLDFD
KTEKILRNYFGDLKKGSLQPLKKTTQAGFNGSKFVSVVHPSTPSKIIGFHKPAFPHPDDAVFSIIDTLLAEGESGRLYKK
LILEKQVAQGVYCWNGDPGDRFSNLFSIYITNNQNADQKKVENLVQEELDKLKTELITSEELFRIKNQILGGYLRALDDN
GKLADVLSLYQLLYGDWRELLRGYEELDTVTPEDVQRVAKKYFVPENRTIAELNPPAKGAGN

Specific function: Unknown

COG id: COG0612

COG function: function code R; Predicted Zn-dependent peptidases

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M16 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011249
- InterPro:   IPR011237
- InterPro:   IPR011765
- InterPro:   IPR001431
- InterPro:   IPR007863 [H]

Pfam domain/function: PF00675 Peptidase_M16; PF05193 Peptidase_M16_C [H]

EC number: NA

Molecular weight: Translated: 62281; Mature: 62281

Theoretical pI: Translated: 8.45; Mature: 8.45

Prosite motif: PS00143 INSULINASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MCFILGILKLFIVCFKVQIFHHKKSSKVLIILGIYLCISNVSVYADTAIFSGLKKSLEEK
CHHHHHHHHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
TRTFQMENGLNVLMMKREDSPTIAVYTKFLVGSADETPEIAGTAHLLEHMLFKGTKNIGT
HHHEECCCCCEEEEEECCCCCEEEEEHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCCC
TNYEKEKPYLEQIAVWGKRLDTLRLKELEMKEKGEEPSDEFKNQIETLKKRFYSLLELHR
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHH
KFVISNEDNYIYSKNGGVGFNAYTSNDVTNYQILLPANRLEIWAKLESDRLKNPILREYY
HHEEECCCCEEEECCCCEEEECCCCCCCCCEEEEEECCHHHHHHEHHHHHCCCHHHHHHH
TERDVVLEERRMRVENRGLGILREKYLDAAFPEGHPYRMPVIGYEKNLGFLDLEKTKTFF
CHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCEECCEEEEECCCCCEEHHHHHHHH
KNYYDPQRMVIAIVGSLDFDKTEKILRNYFGDLKKGSLQPLKKTTQAGFNGSKFVSVVHP
HHCCCHHHEEEHEECCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCCEEEEEECC
STPSKIIGFHKPAFPHPDDAVFSIIDTLLAEGESGRLYKKLILEKQVAQGVYCWNGDPGD
CCCCHHCCCCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCEEEECCCCCH
RFSNLFSIYITNNQNADQKKVENLVQEELDKLKTELITSEELFRIKNQILGGYLRALDDN
HHHCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCC
GKLADVLSLYQLLYGDWRELLRGYEELDTVTPEDVQRVAKKYFVPENRTIAELNPPAKGA
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCEEEECCCCCCCC
GN
CC
>Mature Secondary Structure
MCFILGILKLFIVCFKVQIFHHKKSSKVLIILGIYLCISNVSVYADTAIFSGLKKSLEEK
CHHHHHHHHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
TRTFQMENGLNVLMMKREDSPTIAVYTKFLVGSADETPEIAGTAHLLEHMLFKGTKNIGT
HHHEECCCCCEEEEEECCCCCEEEEEHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCCC
TNYEKEKPYLEQIAVWGKRLDTLRLKELEMKEKGEEPSDEFKNQIETLKKRFYSLLELHR
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHH
KFVISNEDNYIYSKNGGVGFNAYTSNDVTNYQILLPANRLEIWAKLESDRLKNPILREYY
HHEEECCCCEEEECCCCEEEECCCCCCCCCEEEEEECCHHHHHHEHHHHHCCCHHHHHHH
TERDVVLEERRMRVENRGLGILREKYLDAAFPEGHPYRMPVIGYEKNLGFLDLEKTKTFF
CHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCEECCEEEEECCCCCEEHHHHHHHH
KNYYDPQRMVIAIVGSLDFDKTEKILRNYFGDLKKGSLQPLKKTTQAGFNGSKFVSVVHP
HHCCCHHHEEEHEECCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCCEEEEEECC
STPSKIIGFHKPAFPHPDDAVFSIIDTLLAEGESGRLYKKLILEKQVAQGVYCWNGDPGD
CCCCHHCCCCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCEEEECCCCCH
RFSNLFSIYITNNQNADQKKVENLVQEELDKLKTELITSEELFRIKNQILGGYLRALDDN
HHHCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCC
GKLADVLSLYQLLYGDWRELLRGYEELDTVTPEDVQRVAKKYFVPENRTIAELNPPAKGA
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCEEEECCCCCCCC
GN
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9163424 [H]