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The map label for this gene is ydiD [C]

Identifier: 37680851

GI number: 37680851

Start: 2700051

End: 2701736

Strand: Direct

Name: ydiD [C]

Synonym: VV2667

Alternate gene names: 37680851

Gene position: 2700051-2701736 (Clockwise)

Preceding gene: 37680850

Following gene: 37680857

Centisome position: 80.49

GC content: 47.21

Gene sequence:

>1686_bases
ATGATTCAACCTAACGAGTTAAGCAAACCGCAACTTGCTCTCCCTACCCCAAGCGATATGATCCTGAAATGGGCAAAGGA
ACGCCCACATGAGGTATATCTAAAACAGATCATCAACCGACAGTTTGTTGAATTCACCTATTCAGAAGTAGCCGACAAAG
CCCTTCGCTTAGTCACCGCACTCAAAGAACTGGGAGCGGAACCCGGCGATAGAATCGCACTGATCTCTAAAAACTGCGCG
GAGTGGTTTATTTGTGACTTAGCCATGATGCTAGGTGACTATGTGAGCGTACCGATTTTCCCAACCGCCGGAGCGGATAC
GATTGAATACTGCATCACACACAGTGAAAGTAAAATCCTCATTGCCGGTAAACTTGATGATGCCGCCGCAACTCAGAAAG
TGATCGATGATCTGGTTGACGTGAAAAGCATTGCTCTCCCATACGATAGCGCCCCGCATTGCCAATACCAATTTACCACG
CTCATTTTGCAATCGGAGCCGAGCAGCGACAGGCCTCAGCACTACGACGATAAATTGATGTCACTGGTTTACACCTCGGG
AACATCCGGTCTACCGAAAGGGGCAATGCTCACGTACGGCGCGTTTTCATGGTCTGTTCAGCAGTTAATTAACCATATTG
GTATTCAGCCCAACGATCGATTGTTCTCTTATTTGCCACTGGCACATATCACAGAACGCGTCTATATCTTCGGTTCTTCC
ATTATGGGAGGGGTACCTACTGCCTTCCCTGAATCTTTGGATACCTTTATCGAAGACGTAAAAATGCAGCGTCCAACACT
GTTTATTTCTGTGCCACGCTTATGGACCTTATTCCAGCAACGTATTCAAGACAAACTGCCCCAAAAACGCCTCAACTTCC
TACTCAAAATCCCATTTGTCAGCGGTTTGATTAAGAAGAAGTTGGCCGATGGCCTTGGCCTGGATCAAGCCCGAGTGCTG
GGTTGTGGCTCTGCTCCAGTCTCTCCAGCCTTACTCGCGTGGTATCACAGTGTTGGCTTGAACATTACCGAAGCTTGGGG
GATGACAGAATCGTTCGCTTATAGCACCTTAAACTACCCATTTAGAGCCGACAAAATAGGCTCGGTTGGCAACGCAGGAC
CCGGTATTGAGCTGAAAATTGCCGCTGATGATGAGATCATGGTTCGTGGCAAGGGGCTATTTTCTGGATACTACAAAAAC
GACATTGCCACTCAAGAAGCTTTTGATAAAGAAGGCTGGCTACACACTGGCGATATTGGTCGACTGGATGCCGAAGGGTA
TCTCACCATTCAAGGTCGTAAGAAAGACACCTTTAAAACGGCCAAAGGCAAGTTTGTTTCACCTGTCCCTATTGAGAATA
AACTCTTTGAATACAGCCGAGTAGAAATGATGTGTTTGATTGGCCTCGGCTTGCCAGCGCCAATCTTATTGGTGGTTCCG
CATAACTTCCCGAACTTCGATCGCGATCGCTATGAACGCACAACTAAACGTGTGATTGCCAAAATGAACGCGGAACTCGA
ATCGCACGAGCAGATCAAAGGGGTGTTGATGATTAAAGACCCTTGGAGTATCGACAATGGCATCCTAACGCCAACGTTAA
AAATCAAACGACATGTTTTGGAACAGAAATACCACGAAGTGGGGCAAAACTGGCCAAAAGATAAGCTCGTGGTGTGGGAA
GAGTAA

Upstream 100 bases:

>100_bases
TCCGGTTTTTTTTATTTCTGATGAGCATAAAGCATGCTATGGTTAACAATAAATTAACATAACAATAATACTTGTTTTGC
CAATAACATGGAGTTAGAGA

Downstream 100 bases:

>100_bases
TTTTGATGTGAGTCGGTCATTCCGACTCACCACCTGATGGCATCAGCTTTAAAAGCTCGTCATAAAAACTTTTTATGATT
CTCAGACAATAAAAAACCCG

Product: long-chain acyl-CoA synthetase

Products: NA

Alternate protein names: Long-chain acyl-CoA synthetase; LACS [H]

Number of amino acids: Translated: 561; Mature: 561

Protein sequence:

>561_residues
MIQPNELSKPQLALPTPSDMILKWAKERPHEVYLKQIINRQFVEFTYSEVADKALRLVTALKELGAEPGDRIALISKNCA
EWFICDLAMMLGDYVSVPIFPTAGADTIEYCITHSESKILIAGKLDDAAATQKVIDDLVDVKSIALPYDSAPHCQYQFTT
LILQSEPSSDRPQHYDDKLMSLVYTSGTSGLPKGAMLTYGAFSWSVQQLINHIGIQPNDRLFSYLPLAHITERVYIFGSS
IMGGVPTAFPESLDTFIEDVKMQRPTLFISVPRLWTLFQQRIQDKLPQKRLNFLLKIPFVSGLIKKKLADGLGLDQARVL
GCGSAPVSPALLAWYHSVGLNITEAWGMTESFAYSTLNYPFRADKIGSVGNAGPGIELKIAADDEIMVRGKGLFSGYYKN
DIATQEAFDKEGWLHTGDIGRLDAEGYLTIQGRKKDTFKTAKGKFVSPVPIENKLFEYSRVEMMCLIGLGLPAPILLVVP
HNFPNFDRDRYERTTKRVIAKMNAELESHEQIKGVLMIKDPWSIDNGILTPTLKIKRHVLEQKYHEVGQNWPKDKLVVWE
E

Sequences:

>Translated_561_residues
MIQPNELSKPQLALPTPSDMILKWAKERPHEVYLKQIINRQFVEFTYSEVADKALRLVTALKELGAEPGDRIALISKNCA
EWFICDLAMMLGDYVSVPIFPTAGADTIEYCITHSESKILIAGKLDDAAATQKVIDDLVDVKSIALPYDSAPHCQYQFTT
LILQSEPSSDRPQHYDDKLMSLVYTSGTSGLPKGAMLTYGAFSWSVQQLINHIGIQPNDRLFSYLPLAHITERVYIFGSS
IMGGVPTAFPESLDTFIEDVKMQRPTLFISVPRLWTLFQQRIQDKLPQKRLNFLLKIPFVSGLIKKKLADGLGLDQARVL
GCGSAPVSPALLAWYHSVGLNITEAWGMTESFAYSTLNYPFRADKIGSVGNAGPGIELKIAADDEIMVRGKGLFSGYYKN
DIATQEAFDKEGWLHTGDIGRLDAEGYLTIQGRKKDTFKTAKGKFVSPVPIENKLFEYSRVEMMCLIGLGLPAPILLVVP
HNFPNFDRDRYERTTKRVIAKMNAELESHEQIKGVLMIKDPWSIDNGILTPTLKIKRHVLEQKYHEVGQNWPKDKLVVWE
E
>Mature_561_residues
MIQPNELSKPQLALPTPSDMILKWAKERPHEVYLKQIINRQFVEFTYSEVADKALRLVTALKELGAEPGDRIALISKNCA
EWFICDLAMMLGDYVSVPIFPTAGADTIEYCITHSESKILIAGKLDDAAATQKVIDDLVDVKSIALPYDSAPHCQYQFTT
LILQSEPSSDRPQHYDDKLMSLVYTSGTSGLPKGAMLTYGAFSWSVQQLINHIGIQPNDRLFSYLPLAHITERVYIFGSS
IMGGVPTAFPESLDTFIEDVKMQRPTLFISVPRLWTLFQQRIQDKLPQKRLNFLLKIPFVSGLIKKKLADGLGLDQARVL
GCGSAPVSPALLAWYHSVGLNITEAWGMTESFAYSTLNYPFRADKIGSVGNAGPGIELKIAADDEIMVRGKGLFSGYYKN
DIATQEAFDKEGWLHTGDIGRLDAEGYLTIQGRKKDTFKTAKGKFVSPVPIENKLFEYSRVEMMCLIGLGLPAPILLVVP
HNFPNFDRDRYERTTKRVIAKMNAELESHEQIKGVLMIKDPWSIDNGILTPTLKIKRHVLEQKYHEVGQNWPKDKLVVWE
E

Specific function: Unknown

COG id: COG1022

COG function: function code I; Long-chain acyl-CoA synthetases (AMP-forming)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATP-dependent AMP-binding enzyme family [H]

Homologues:

Organism=Homo sapiens, GI42794756, Length=577, Percent_Identity=27.9029462738302, Blast_Score=194, Evalue=2e-49,
Organism=Homo sapiens, GI42794760, Length=577, Percent_Identity=27.9029462738302, Blast_Score=194, Evalue=2e-49,
Organism=Homo sapiens, GI42794758, Length=577, Percent_Identity=27.9029462738302, Blast_Score=194, Evalue=2e-49,
Organism=Homo sapiens, GI57165412, Length=568, Percent_Identity=31.1619718309859, Blast_Score=192, Evalue=9e-49,
Organism=Homo sapiens, GI57165410, Length=566, Percent_Identity=30.9187279151943, Blast_Score=187, Evalue=2e-47,
Organism=Homo sapiens, GI40807491, Length=572, Percent_Identity=29.3706293706294, Blast_Score=184, Evalue=2e-46,
Organism=Homo sapiens, GI83745141, Length=579, Percent_Identity=25.2158894645941, Blast_Score=165, Evalue=1e-40,
Organism=Homo sapiens, GI27477105, Length=581, Percent_Identity=25.1290877796902, Blast_Score=164, Evalue=1e-40,
Organism=Homo sapiens, GI42794754, Length=598, Percent_Identity=24.247491638796, Blast_Score=137, Evalue=2e-32,
Organism=Homo sapiens, GI42794752, Length=598, Percent_Identity=24.247491638796, Blast_Score=137, Evalue=2e-32,
Organism=Homo sapiens, GI4758332, Length=602, Percent_Identity=23.421926910299, Blast_Score=125, Evalue=2e-28,
Organism=Homo sapiens, GI12669909, Length=602, Percent_Identity=23.421926910299, Blast_Score=124, Evalue=2e-28,
Organism=Homo sapiens, GI187761345, Length=476, Percent_Identity=23.9495798319328, Blast_Score=101, Evalue=1e-21,
Organism=Homo sapiens, GI187761343, Length=476, Percent_Identity=23.9495798319328, Blast_Score=101, Evalue=1e-21,
Organism=Escherichia coli, GI145693145, Length=478, Percent_Identity=24.0585774058577, Blast_Score=119, Evalue=5e-28,
Organism=Escherichia coli, GI1788107, Length=483, Percent_Identity=25.6728778467909, Blast_Score=100, Evalue=4e-22,
Organism=Escherichia coli, GI1786810, Length=450, Percent_Identity=23.3333333333333, Blast_Score=84, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI17510401, Length=568, Percent_Identity=28.3450704225352, Blast_Score=197, Evalue=1e-50,
Organism=Caenorhabditis elegans, GI17556552, Length=577, Percent_Identity=27.7296360485269, Blast_Score=173, Evalue=2e-43,
Organism=Caenorhabditis elegans, GI17541856, Length=576, Percent_Identity=27.7777777777778, Blast_Score=160, Evalue=1e-39,
Organism=Caenorhabditis elegans, GI25147511, Length=580, Percent_Identity=23.9655172413793, Blast_Score=139, Evalue=4e-33,
Organism=Caenorhabditis elegans, GI17564090, Length=598, Percent_Identity=23.0769230769231, Blast_Score=138, Evalue=7e-33,
Organism=Caenorhabditis elegans, GI17558820, Length=493, Percent_Identity=26.369168356998, Blast_Score=138, Evalue=9e-33,
Organism=Caenorhabditis elegans, GI32563687, Length=488, Percent_Identity=27.4590163934426, Blast_Score=132, Evalue=7e-31,
Organism=Caenorhabditis elegans, GI193204819, Length=595, Percent_Identity=24.5378151260504, Blast_Score=129, Evalue=4e-30,
Organism=Caenorhabditis elegans, GI17553312, Length=588, Percent_Identity=24.3197278911565, Blast_Score=129, Evalue=4e-30,
Organism=Caenorhabditis elegans, GI17531443, Length=516, Percent_Identity=23.4496124031008, Blast_Score=95, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17557194, Length=458, Percent_Identity=25.1091703056769, Blast_Score=86, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI71985884, Length=304, Percent_Identity=26.9736842105263, Blast_Score=82, Evalue=7e-16,
Organism=Caenorhabditis elegans, GI17559526, Length=341, Percent_Identity=27.2727272727273, Blast_Score=80, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI115534440, Length=500, Percent_Identity=21.6, Blast_Score=76, Evalue=4e-14,
Organism=Saccharomyces cerevisiae, GI6320852, Length=594, Percent_Identity=24.7474747474747, Blast_Score=162, Evalue=1e-40,
Organism=Saccharomyces cerevisiae, GI6324893, Length=428, Percent_Identity=25, Blast_Score=111, Evalue=4e-25,
Organism=Saccharomyces cerevisiae, GI6323903, Length=416, Percent_Identity=25.7211538461538, Blast_Score=109, Evalue=1e-24,
Organism=Saccharomyces cerevisiae, GI6322182, Length=446, Percent_Identity=26.457399103139, Blast_Score=107, Evalue=4e-24,
Organism=Saccharomyces cerevisiae, GI6319699, Length=524, Percent_Identity=20.8015267175573, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI17933690, Length=590, Percent_Identity=24.9152542372881, Blast_Score=187, Evalue=2e-47,
Organism=Drosophila melanogaster, GI24666501, Length=564, Percent_Identity=27.8368794326241, Blast_Score=183, Evalue=3e-46,
Organism=Drosophila melanogaster, GI24666497, Length=564, Percent_Identity=27.8368794326241, Blast_Score=183, Evalue=3e-46,
Organism=Drosophila melanogaster, GI281366413, Length=564, Percent_Identity=27.8368794326241, Blast_Score=183, Evalue=3e-46,
Organism=Drosophila melanogaster, GI19921316, Length=478, Percent_Identity=26.1506276150628, Blast_Score=159, Evalue=6e-39,
Organism=Drosophila melanogaster, GI62471681, Length=584, Percent_Identity=24.8287671232877, Blast_Score=141, Evalue=1e-33,
Organism=Drosophila melanogaster, GI62471687, Length=584, Percent_Identity=24.8287671232877, Blast_Score=141, Evalue=1e-33,
Organism=Drosophila melanogaster, GI24586634, Length=584, Percent_Identity=24.8287671232877, Blast_Score=141, Evalue=1e-33,
Organism=Drosophila melanogaster, GI22026970, Length=584, Percent_Identity=24.8287671232877, Blast_Score=141, Evalue=1e-33,
Organism=Drosophila melanogaster, GI62471679, Length=584, Percent_Identity=24.8287671232877, Blast_Score=140, Evalue=2e-33,
Organism=Drosophila melanogaster, GI62471683, Length=584, Percent_Identity=24.8287671232877, Blast_Score=140, Evalue=2e-33,
Organism=Drosophila melanogaster, GI62471685, Length=584, Percent_Identity=24.8287671232877, Blast_Score=140, Evalue=2e-33,
Organism=Drosophila melanogaster, GI24586636, Length=584, Percent_Identity=24.8287671232877, Blast_Score=140, Evalue=2e-33,
Organism=Drosophila melanogaster, GI62471689, Length=584, Percent_Identity=24.8287671232877, Blast_Score=140, Evalue=2e-33,
Organism=Drosophila melanogaster, GI21355181, Length=450, Percent_Identity=25.3333333333333, Blast_Score=96, Evalue=8e-20,
Organism=Drosophila melanogaster, GI24648255, Length=462, Percent_Identity=23.1601731601732, Blast_Score=89, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24648253, Length=465, Percent_Identity=23.2258064516129, Blast_Score=87, Evalue=3e-17,
Organism=Drosophila melanogaster, GI24581924, Length=477, Percent_Identity=22.6415094339623, Blast_Score=85, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24648260, Length=515, Percent_Identity=24.0776699029126, Blast_Score=84, Evalue=3e-16,
Organism=Drosophila melanogaster, GI21356947, Length=495, Percent_Identity=22.8282828282828, Blast_Score=81, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24653035, Length=136, Percent_Identity=34.5588235294118, Blast_Score=74, Evalue=3e-13,
Organism=Drosophila melanogaster, GI281365686, Length=213, Percent_Identity=29.5774647887324, Blast_Score=73, Evalue=4e-13,
Organism=Drosophila melanogaster, GI24648257, Length=472, Percent_Identity=20.9745762711864, Blast_Score=71, Evalue=2e-12,
Organism=Drosophila melanogaster, GI161076582, Length=135, Percent_Identity=34.0740740740741, Blast_Score=70, Evalue=3e-12,
Organism=Drosophila melanogaster, GI21358303, Length=505, Percent_Identity=22.970297029703, Blast_Score=67, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020845
- InterPro:   IPR000873 [H]

Pfam domain/function: PF00501 AMP-binding [H]

EC number: =6.2.1.3 [H]

Molecular weight: Translated: 62973; Mature: 62973

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: PS00455 AMP_BINDING

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIQPNELSKPQLALPTPSDMILKWAKERPHEVYLKQIINRQFVEFTYSEVADKALRLVTA
CCCCCCCCCCEEECCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LKELGAEPGDRIALISKNCAEWFICDLAMMLGDYVSVPIFPTAGADTIEYCITHSESKIL
HHHHCCCCCCEEEEECCCHHHHHHHHHHHHHCCCCCCCEECCCCCHHHHHHHCCCCCEEE
IAGKLDDAAATQKVIDDLVDVKSIALPYDSAPHCQYQFTTLILQSEPSSDRPQHYDDKLM
EEECCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEEEEECCCCCCCCCHHHHHHH
SLVYTSGTSGLPKGAMLTYGAFSWSVQQLINHIGIQPNDRLFSYLPLAHITERVYIFGSS
HHHEECCCCCCCCCCEEEECCHHHHHHHHHHHCCCCCCCCHHHHCCHHHHHCEEEEEECH
IMGGVPTAFPESLDTFIEDVKMQRPTLFISVPRLWTLFQQRIQDKLPQKRLNFLLKIPFV
HCCCCCCCCHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHCCHHHHHHEEECHHH
SGLIKKKLADGLGLDQARVLGCGSAPVSPALLAWYHSVGLNITEAWGMTESFAYSTLNYP
HHHHHHHHHCCCCCCCHHEEECCCCCCCHHHHHHHHHCCCCEEHHCCCCHHHHHHHCCCC
FRADKIGSVGNAGPGIELKIAADDEIMVRGKGLFSGYYKNDIATQEAFDKEGWLHTGDIG
CCCCCCCCCCCCCCCEEEEEECCCEEEEECCCCCCCHHHCCCHHHHHHCCCCCEEECCCC
RLDAEGYLTIQGRKKDTFKTAKGKFVSPVPIENKLFEYSRVEMMCLIGLGLPAPILLVVP
CCCCCCEEEEECCCCCCHHHCCCCCCCCCCCHHHHHHHHHHHHHHEECCCCCCCEEEEEC
HNFPNFDRDRYERTTKRVIAKMNAELESHEQIKGVLMIKDPWSIDNGILTPTLKIKRHVL
CCCCCCCHHHHHHHHHHHHHHHHCCHHCCCCCCEEEEEECCCCCCCCEECCHHHHHHHHH
EQKYHEVGQNWPKDKLVVWEE
HHHHHHHHCCCCCCCEEEECC
>Mature Secondary Structure
MIQPNELSKPQLALPTPSDMILKWAKERPHEVYLKQIINRQFVEFTYSEVADKALRLVTA
CCCCCCCCCCEEECCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LKELGAEPGDRIALISKNCAEWFICDLAMMLGDYVSVPIFPTAGADTIEYCITHSESKIL
HHHHCCCCCCEEEEECCCHHHHHHHHHHHHHCCCCCCCEECCCCCHHHHHHHCCCCCEEE
IAGKLDDAAATQKVIDDLVDVKSIALPYDSAPHCQYQFTTLILQSEPSSDRPQHYDDKLM
EEECCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEEEEECCCCCCCCCHHHHHHH
SLVYTSGTSGLPKGAMLTYGAFSWSVQQLINHIGIQPNDRLFSYLPLAHITERVYIFGSS
HHHEECCCCCCCCCCEEEECCHHHHHHHHHHHCCCCCCCCHHHHCCHHHHHCEEEEEECH
IMGGVPTAFPESLDTFIEDVKMQRPTLFISVPRLWTLFQQRIQDKLPQKRLNFLLKIPFV
HCCCCCCCCHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHCCHHHHHHEEECHHH
SGLIKKKLADGLGLDQARVLGCGSAPVSPALLAWYHSVGLNITEAWGMTESFAYSTLNYP
HHHHHHHHHCCCCCCCHHEEECCCCCCCHHHHHHHHHCCCCEEHHCCCCHHHHHHHCCCC
FRADKIGSVGNAGPGIELKIAADDEIMVRGKGLFSGYYKNDIATQEAFDKEGWLHTGDIG
CCCCCCCCCCCCCCCEEEEEECCCEEEEECCCCCCCHHHCCCHHHHHHCCCCCEEECCCC
RLDAEGYLTIQGRKKDTFKTAKGKFVSPVPIENKLFEYSRVEMMCLIGLGLPAPILLVVP
CCCCCCEEEEECCCCCCHHHCCCCCCCCCCCHHHHHHHHHHHHHHEECCCCCCCEEEEEC
HNFPNFDRDRYERTTKRVIAKMNAELESHEQIKGVLMIKDPWSIDNGILTPTLKIKRHVL
CCCCCCCHHHHHHHHHHHHHHHHCCHHCCCCCCEEEEEECCCCCCCCEECCHHHHHHHHH
EQKYHEVGQNWPKDKLVVWEE
HHHHHHHHCCCCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]