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The map label for this gene is dapE [H]

Identifier: 37680684

GI number: 37680684

Start: 2531643

End: 2532848

Strand: Direct

Name: dapE [H]

Synonym: VV2500

Alternate gene names: 37680684

Gene position: 2531643-2532848 (Clockwise)

Preceding gene: 37680683

Following gene: 37680685

Centisome position: 75.47

GC content: 50.91

Gene sequence:

>1206_bases
ATGACCAGCTACACGTTGGCTTTAAAGCAGAACAGTATTCAAAAATTTTCAATTAATGAAGGATTATCAAGGATGACAGA
CAGCCCAGTACTGGCTCTAACCAAAGATCTCATCAGTCGCCAGTCGGTAACCCCCGAAGACGCCGGTTGCCAAGATGTCA
TGATAGCGCGCCTAGAGGCTCTCGGTTTTACCATTGAGCGCATGGTGTTTGAAGATACCACCAACTTTTGGGCTCGCCGT
GGCACACAAGCGCCACTCTTCGCCTTTGCAGGCCACACTGACGTGGTGCCCGCTGGTAAATTAGAGCATTGGCACACACC
GCCTTTTGAACCGACCGAAAAAGAAGGCTATTTGTATGGCCGCGGGGCTGCGGATATGAAAGGCTCATTGGCAGCAATGA
TCGTCGCGACGGAGCGTTTTATCGCAGAACATCCCGATCATCAGGGTTCTATCGGTTTCCTGATCACCTCAGATGAGGAA
GGCCCGTTTATCAATGGCACGGTTCGCGTTGTGGAAACGTTGATGGCGCGCGATGAAAACATCGACATGTGTATTGTCGG
CGAGCCATCAAGCACCGAAGTCGTTGGTGATGTGGTAAAAAATGGTCGTCGTGGTTCGATCACTGGCGACTTAACCGTCA
TAGGGACTCAAGGCCATGTGGCTTACCCTCATCTTGCGGACAACCCAGTGCACAAATCGCTTTTGGCAATCCACGCCCTA
GCGACCACTGAGTGGGACAAGGGTAATGAATACTTCCCGCCAACCAGCTTCCAGATCCCGAACGTACAAGCGGGTACGGG
TGCGTCCAATGTTATCCCAGGAGAGTTCCACGTTCAGTTCAATTTGCGCTTTAGTACCGAGCTTTGCAACGAGCGAATTG
TGGAACGAGTGACTCAAACACTCGACCAACATGACCTCAATTACGATCTCAAATGGACATACAACGGCGACCCATTCCTA
ACTGATACGGGAGCACTTCTGGACGCGGTGGTGGATGCTGTCGATAGCGTCAACCAAACCAAACCCGCGTTACTGACCAC
TGGCGGTACTTCAGACGGACGCTTTATCGCACGAATGGGTGGACAAGTAGTTGAGCTCGGACCGGTGAACGCCACCATCC
ATAAAGTGAACGAGTGCGTGAAGATCGATGACTTAGAAAAGCTCACCGATATGTACCAGAAAACATTGGAAAACTTATTG
GCATGA

Upstream 100 bases:

>100_bases
CAGTTGACTGACGAGCAAAAAGAGTCGCTCAATGAGACAACCGCCGTTGATTTGCTAGTCGCACACCCTGCGATGATCAA
ACGCCCAATTTTGCGAGTCA

Downstream 100 bases:

>100_bases
ACACCATTGAGCAGCTGACTGGCAGCGAAACGTCTCATTTAGAACACGTTTTAGTGGGGGAGAAATGGTTTTGGCTCCAC
CCTGAGGTGAAAAATGATCT

Product: succinyl-diaminopimelate desuccinylase

Products: NA

Alternate protein names: SDAP desuccinylase; N-succinyl-LL-2,6-diaminoheptanedioate amidohydrolase [H]

Number of amino acids: Translated: 401; Mature: 400

Protein sequence:

>401_residues
MTSYTLALKQNSIQKFSINEGLSRMTDSPVLALTKDLISRQSVTPEDAGCQDVMIARLEALGFTIERMVFEDTTNFWARR
GTQAPLFAFAGHTDVVPAGKLEHWHTPPFEPTEKEGYLYGRGAADMKGSLAAMIVATERFIAEHPDHQGSIGFLITSDEE
GPFINGTVRVVETLMARDENIDMCIVGEPSSTEVVGDVVKNGRRGSITGDLTVIGTQGHVAYPHLADNPVHKSLLAIHAL
ATTEWDKGNEYFPPTSFQIPNVQAGTGASNVIPGEFHVQFNLRFSTELCNERIVERVTQTLDQHDLNYDLKWTYNGDPFL
TDTGALLDAVVDAVDSVNQTKPALLTTGGTSDGRFIARMGGQVVELGPVNATIHKVNECVKIDDLEKLTDMYQKTLENLL
A

Sequences:

>Translated_401_residues
MTSYTLALKQNSIQKFSINEGLSRMTDSPVLALTKDLISRQSVTPEDAGCQDVMIARLEALGFTIERMVFEDTTNFWARR
GTQAPLFAFAGHTDVVPAGKLEHWHTPPFEPTEKEGYLYGRGAADMKGSLAAMIVATERFIAEHPDHQGSIGFLITSDEE
GPFINGTVRVVETLMARDENIDMCIVGEPSSTEVVGDVVKNGRRGSITGDLTVIGTQGHVAYPHLADNPVHKSLLAIHAL
ATTEWDKGNEYFPPTSFQIPNVQAGTGASNVIPGEFHVQFNLRFSTELCNERIVERVTQTLDQHDLNYDLKWTYNGDPFL
TDTGALLDAVVDAVDSVNQTKPALLTTGGTSDGRFIARMGGQVVELGPVNATIHKVNECVKIDDLEKLTDMYQKTLENLL
A
>Mature_400_residues
TSYTLALKQNSIQKFSINEGLSRMTDSPVLALTKDLISRQSVTPEDAGCQDVMIARLEALGFTIERMVFEDTTNFWARRG
TQAPLFAFAGHTDVVPAGKLEHWHTPPFEPTEKEGYLYGRGAADMKGSLAAMIVATERFIAEHPDHQGSIGFLITSDEEG
PFINGTVRVVETLMARDENIDMCIVGEPSSTEVVGDVVKNGRRGSITGDLTVIGTQGHVAYPHLADNPVHKSLLAIHALA
TTEWDKGNEYFPPTSFQIPNVQAGTGASNVIPGEFHVQFNLRFSTELCNERIVERVTQTLDQHDLNYDLKWTYNGDPFLT
DTGALLDAVVDAVDSVNQTKPALLTTGGTSDGRFIARMGGQVVELGPVNATIHKVNECVKIDDLEKLTDMYQKTLENLLA

Specific function: Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bact

COG id: COG0624

COG function: function code E; Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M20A family. DapE subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788816, Length=374, Percent_Identity=64.7058823529412, Blast_Score=513, Evalue=1e-147,
Organism=Caenorhabditis elegans, GI17551016, Length=217, Percent_Identity=28.110599078341, Blast_Score=72, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001261
- InterPro:   IPR005941
- InterPro:   IPR002933
- InterPro:   IPR011650 [H]

Pfam domain/function: PF07687 M20_dimer; PF01546 Peptidase_M20 [H]

EC number: =3.5.1.18 [H]

Molecular weight: Translated: 43924; Mature: 43793

Theoretical pI: Translated: 4.65; Mature: 4.65

Prosite motif: PS00759 ARGE_DAPE_CPG2_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSYTLALKQNSIQKFSINEGLSRMTDSPVLALTKDLISRQSVTPEDAGCQDVMIARLEA
CCCEEEEEECCCCEEEEHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHH
LGFTIERMVFEDTTNFWARRGTQAPLFAFAGHTDVVPAGKLEHWHTPPFEPTEKEGYLYG
HHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCEEEE
RGAADMKGSLAAMIVATERFIAEHPDHQGSIGFLITSDEEGPFINGTVRVVETLMARDEN
CCCCCCCCCCEEEEHHHHHHHHHCCCCCCCEEEEEECCCCCCEECHHHHHHHHHHHCCCC
IDMCIVGEPSSTEVVGDVVKNGRRGSITGDLTVIGTQGHVAYPHLADNPVHKSLLAIHAL
CCEEEECCCCCHHHHHHHHHCCCCCCEEEEEEEEECCCCEECCCCCCCHHHHHHHHHHHH
ATTEWDKGNEYFPPTSFQIPNVQAGTGASNVIPGEFHVQFNLRFSTELCNERIVERVTQT
HHCCCCCCCCCCCCCCEECCCCCCCCCCCCCCCCEEEEEEEEEECHHHHHHHHHHHHHHH
LDQHDLNYDLKWTYNGDPFLTDTGALLDAVVDAVDSVNQTKPALLTTGGTSDGRFIARMG
HHHHCCCEEEEEEECCCCEEECHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCEEHHHCC
GQVVELGPVNATIHKVNECVKIDDLEKLTDMYQKTLENLLA
CEEEEECCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TSYTLALKQNSIQKFSINEGLSRMTDSPVLALTKDLISRQSVTPEDAGCQDVMIARLEA
CCEEEEEECCCCEEEEHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHH
LGFTIERMVFEDTTNFWARRGTQAPLFAFAGHTDVVPAGKLEHWHTPPFEPTEKEGYLYG
HHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCEEEE
RGAADMKGSLAAMIVATERFIAEHPDHQGSIGFLITSDEEGPFINGTVRVVETLMARDEN
CCCCCCCCCCEEEEHHHHHHHHHCCCCCCCEEEEEECCCCCCEECHHHHHHHHHHHCCCC
IDMCIVGEPSSTEVVGDVVKNGRRGSITGDLTVIGTQGHVAYPHLADNPVHKSLLAIHAL
CCEEEECCCCCHHHHHHHHHCCCCCCEEEEEEEEECCCCEECCCCCCCHHHHHHHHHHHH
ATTEWDKGNEYFPPTSFQIPNVQAGTGASNVIPGEFHVQFNLRFSTELCNERIVERVTQT
HHCCCCCCCCCCCCCCEECCCCCCCCCCCCCCCCEEEEEEEEEECHHHHHHHHHHHHHHH
LDQHDLNYDLKWTYNGDPFLTDTGALLDAVVDAVDSVNQTKPALLTTGGTSDGRFIARMG
HHHHCCCEEEEEEECCCCEEECHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCEEHHHCC
GQVVELGPVNATIHKVNECVKIDDLEKLTDMYQKTLENLLA
CEEEEECCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA