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The map label for this gene is dctS [H]

Identifier: 37680407

GI number: 37680407

Start: 2242723

End: 2244633

Strand: Direct

Name: dctS [H]

Synonym: VV2223

Alternate gene names: 37680407

Gene position: 2242723-2244633 (Clockwise)

Preceding gene: 37680403

Following gene: 37680408

Centisome position: 66.86

GC content: 50.29

Gene sequence:

>1911_bases
ATGCAGATAAAACTCGCCCCCCTCGCTCGCTTATGGATTGCTTTGATCTTTTTATTCTCAGTAACAACTTACGCCCAAAC
ACAAGCTAATACTCTCGAGCCCGCACAAAGCGCAAACGCAGCGCGTAAACCGCAAATTGATGTTGGCGTTTTGGCCACTC
GCGGCCATTTGTATGCCCACCAGCGCTGGCAACCGACCATCTATTGGCTCAATCAACAGATCCCACAAGTGCACTTTGTA
CTGCACCCGCTCGATCTCGATGGCATGACCCAAGCGGTTGAGCAGCAAAGCATGGATTTTATCCTTACCAACCCAGGGCA
AGCGGTACGCTTAGGAAGACAATACGCCCTCTCATGGGTGGCAACGCTAACTAGCGAGGCACCGGAAAACTCTAACTATG
GTATTGGCTCGGCGTTAGTGGTGCGCGCAAACTCCCCATACCAAACACTTGACGATGTAGCAGGCTTACCGATGGCCGCC
GTAGCGGAAAAAGCATTTGGCGGATACCTAACACTACGCTACCAAGTTATTGAGCAAGGCCTTAACCCGAACGATTTTTT
TGCTGATGTGCGCTACTTAGGCTTCCCGATTGATGCCAGCCTTTATCAACTGCGTGACCAAACTATCGAGGCAGCAGTGG
TGCCTGCTTGCTTAAAAGAGCAGATGGAAAACGAAGGCTTGATAGAGCAAGGGCAATTGCGCGTACTTAACCCGCTGAAT
GAACCGCAAACCCAATGTGAAGTCTCTACCCCGCTCTACCCCAATTGGTCATTTGCTAAAACAGAGCGTGGATCTTCACA
ACTGGCTAAACAAATAAGCCGCGCGCTGCTGGCGATGCCTGCCGATAACCCGGCGGCAATTGCCGCAAAAGCCTCGGGGT
GGACCTCTCCAGTGAGCTTGCTCTCCATTGATAAACTCTACCAAGCGATGGACTTACACCCTCTGCAACAGCCATGGTGG
AAAGACGCGCTGCGTTGGCTGCGCGCCCATCAAGAGTGGGCATGGGCGCTGTTTTTGTTTGTCATTGTGCTCAACATTTA
CCATTTCTGGTTGGAGTATCGCTTCAGTAAAAGCAAACAAGCTTTAGAGCAAACCCAGCAGCGATTAAAAGAAAAAAGCG
AGCTATTAGAACATTCGCAACGCGTCGCGATCGTCGGCGAACTGGGCAGTAGTTTGGCCCACGAACTAAACCAGCCGCTG
GCCGCCATTCGTAATTACAGTGAAGGCGTGCTACTGCGTTTAGCCAAAAACCGCCCCAACCAAGAGATAGTGCCGGTACT
GGAAAAAATTCAGCGGCAAGTGGAGCGCGCTGATGCGATTGTCTCACGCCTGCGTAACTTAATTAAAAAGCGCAGCGTTG
CTATCAGCAAATTCGATTTGCCGCAGCTTATTAGCGACACTCTCGAGCTAATGCAGTTTCGATTACAAAAGCAGATGGTT
GAGGTGGTATGCAGCTCAGAAGGCCAACAACACCCGATTGAAGCGGACATGGTGGGGCTGCAGCAAGTGCTAGTCAACGT
CATTAATAACGCCATCGACGCGTGCGTGAGTTATGCCAAGCTGCACCCTGAACAATACTCGAGCAAAATTGCCATCCACA
CTGATTTTGCAACGCAAGGCGTTACGATTCGCATCCTAGATAACGGTACTGGTTTAAAACAAGAGAACCCGACCGAAGCG
TTTGTCAGTTCCAAACAAGAAGGGCTGGGTTTAGGCTTATCGATTTGTCGAGATGTGCTTGAAATGCATGGCGGCGAATT
TACCATTCAGTCGTCCAATCCACATGGTTGTCTGGTAGAACTCTGTTTGCCCTACCAAGCAGTGCCATCATTGAGCAAAA
ACGCAATGAGCACTCCAAACGCAGCCACAGACAGCACAAACAGCACAAAAGGAACGAGAAATGAGTGGTAA

Upstream 100 bases:

>100_bases
ATTTCCACATACCGCAATCATTGTTGATCTAAAACAAATATCGATTGCGCTCTGTAGCTGATATTCTGAGGTTCAAAGTA
AAAAGGACTCAGACCAATTC

Downstream 100 bases:

>100_bases
ACAATTACCCGTCTATGTGGTGGATGATGATGAATCAGTGCGAGATTCGCTGGCATTTATGCTCGAGGAGTATGACTTTT
TAGTGACCACCTTTGCCGAT

Product: putative tetrathionate reductase complex, sensory transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 636; Mature: 636

Protein sequence:

>636_residues
MQIKLAPLARLWIALIFLFSVTTYAQTQANTLEPAQSANAARKPQIDVGVLATRGHLYAHQRWQPTIYWLNQQIPQVHFV
LHPLDLDGMTQAVEQQSMDFILTNPGQAVRLGRQYALSWVATLTSEAPENSNYGIGSALVVRANSPYQTLDDVAGLPMAA
VAEKAFGGYLTLRYQVIEQGLNPNDFFADVRYLGFPIDASLYQLRDQTIEAAVVPACLKEQMENEGLIEQGQLRVLNPLN
EPQTQCEVSTPLYPNWSFAKTERGSSQLAKQISRALLAMPADNPAAIAAKASGWTSPVSLLSIDKLYQAMDLHPLQQPWW
KDALRWLRAHQEWAWALFLFVIVLNIYHFWLEYRFSKSKQALEQTQQRLKEKSELLEHSQRVAIVGELGSSLAHELNQPL
AAIRNYSEGVLLRLAKNRPNQEIVPVLEKIQRQVERADAIVSRLRNLIKKRSVAISKFDLPQLISDTLELMQFRLQKQMV
EVVCSSEGQQHPIEADMVGLQQVLVNVINNAIDACVSYAKLHPEQYSSKIAIHTDFATQGVTIRILDNGTGLKQENPTEA
FVSSKQEGLGLGLSICRDVLEMHGGEFTIQSSNPHGCLVELCLPYQAVPSLSKNAMSTPNAATDSTNSTKGTRNEW

Sequences:

>Translated_636_residues
MQIKLAPLARLWIALIFLFSVTTYAQTQANTLEPAQSANAARKPQIDVGVLATRGHLYAHQRWQPTIYWLNQQIPQVHFV
LHPLDLDGMTQAVEQQSMDFILTNPGQAVRLGRQYALSWVATLTSEAPENSNYGIGSALVVRANSPYQTLDDVAGLPMAA
VAEKAFGGYLTLRYQVIEQGLNPNDFFADVRYLGFPIDASLYQLRDQTIEAAVVPACLKEQMENEGLIEQGQLRVLNPLN
EPQTQCEVSTPLYPNWSFAKTERGSSQLAKQISRALLAMPADNPAAIAAKASGWTSPVSLLSIDKLYQAMDLHPLQQPWW
KDALRWLRAHQEWAWALFLFVIVLNIYHFWLEYRFSKSKQALEQTQQRLKEKSELLEHSQRVAIVGELGSSLAHELNQPL
AAIRNYSEGVLLRLAKNRPNQEIVPVLEKIQRQVERADAIVSRLRNLIKKRSVAISKFDLPQLISDTLELMQFRLQKQMV
EVVCSSEGQQHPIEADMVGLQQVLVNVINNAIDACVSYAKLHPEQYSSKIAIHTDFATQGVTIRILDNGTGLKQENPTEA
FVSSKQEGLGLGLSICRDVLEMHGGEFTIQSSNPHGCLVELCLPYQAVPSLSKNAMSTPNAATDSTNSTKGTRNEW
>Mature_636_residues
MQIKLAPLARLWIALIFLFSVTTYAQTQANTLEPAQSANAARKPQIDVGVLATRGHLYAHQRWQPTIYWLNQQIPQVHFV
LHPLDLDGMTQAVEQQSMDFILTNPGQAVRLGRQYALSWVATLTSEAPENSNYGIGSALVVRANSPYQTLDDVAGLPMAA
VAEKAFGGYLTLRYQVIEQGLNPNDFFADVRYLGFPIDASLYQLRDQTIEAAVVPACLKEQMENEGLIEQGQLRVLNPLN
EPQTQCEVSTPLYPNWSFAKTERGSSQLAKQISRALLAMPADNPAAIAAKASGWTSPVSLLSIDKLYQAMDLHPLQQPWW
KDALRWLRAHQEWAWALFLFVIVLNIYHFWLEYRFSKSKQALEQTQQRLKEKSELLEHSQRVAIVGELGSSLAHELNQPL
AAIRNYSEGVLLRLAKNRPNQEIVPVLEKIQRQVERADAIVSRLRNLIKKRSVAISKFDLPQLISDTLELMQFRLQKQMV
EVVCSSEGQQHPIEADMVGLQQVLVNVINNAIDACVSYAKLHPEQYSSKIAIHTDFATQGVTIRILDNGTGLKQENPTEA
FVSSKQEGLGLGLSICRDVLEMHGGEFTIQSSNPHGCLVELCLPYQAVPSLSKNAMSTPNAATDSTNSTKGTRNEW

Specific function: Member of the two-component regulatory system dctS/dctR involved in the transport of C4-dicarboxylates. DctS functions as a membrane-associated protein kinase that phosphorylates dctR in response to environmental signals [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1790436, Length=275, Percent_Identity=27.2727272727273, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI1788549, Length=241, Percent_Identity=28.6307053941909, Blast_Score=94, Evalue=3e-20,
Organism=Escherichia coli, GI1790861, Length=260, Percent_Identity=26.5384615384615, Blast_Score=64, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 71068; Mature: 71068

Theoretical pI: Translated: 6.63; Mature: 6.63

Prosite motif: PS50109 HIS_KIN ; PS00133 CARBOXYPEPT_ZN_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQIKLAPLARLWIALIFLFSVTTYAQTQANTLEPAQSANAARKPQIDVGVLATRGHLYAH
CCEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHCCCCCCCCCCEEEEEECCCEEEC
QRWQPTIYWLNQQIPQVHFVLHPLDLDGMTQAVEQQSMDFILTNPGQAVRLGRQYALSWV
CCCCCEEEECCCCCCEEEEEEECCCCCHHHHHHHHHCCCEEEECCCHHHHHHHHHHHHHH
ATLTSEAPENSNYGIGSALVVRANSPYQTLDDVAGLPMAAVAEKAFGGYLTLRYQVIEQG
HHHHHCCCCCCCCCCCCEEEEECCCCHHHHHHHCCCCHHHHHHHHCCCHHEEHHHHHHCC
LNPNDFFADVRYLGFPIDASLYQLRDQTIEAAVVPACLKEQMENEGLIEQGQLRVLNPLN
CCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCC
EPQTQCEVSTPLYPNWSFAKTERGSSQLAKQISRALLAMPADNPAAIAAKASGWTSPVSL
CCCCCEEECCCCCCCCCCHHCCCCHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCHHHH
LSIDKLYQAMDLHPLQQPWWKDALRWLRAHQEWAWALFLFVIVLNIYHFWLEYRFSKSKQ
HHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALEQTQQRLKEKSELLEHSQRVAIVGELGSSLAHELNQPLAAIRNYSEGVLLRLAKNRPN
HHHHHHHHHHHHHHHHHHHCCEEEHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCC
QEIVPVLEKIQRQVERADAIVSRLRNLIKKRSVAISKFDLPQLISDTLELMQFRLQKQMV
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
EVVCSSEGQQHPIEADMVGLQQVLVNVINNAIDACVSYAKLHPEQYSSKIAIHTDFATQG
HHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHCCEEEEEECCCCCC
VTIRILDNGTGLKQENPTEAFVSSKQEGLGLGLSICRDVLEMHGGEFTIQSSNPHGCLVE
EEEEEEECCCCCCCCCCHHHHHCCCCCCCCCCHHHHHHHHHHCCCEEEEECCCCCCCHHH
LCLPYQAVPSLSKNAMSTPNAATDSTNSTKGTRNEW
HHCCHHHHCCHHHHCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MQIKLAPLARLWIALIFLFSVTTYAQTQANTLEPAQSANAARKPQIDVGVLATRGHLYAH
CCEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHCCCCCCCCCCEEEEEECCCEEEC
QRWQPTIYWLNQQIPQVHFVLHPLDLDGMTQAVEQQSMDFILTNPGQAVRLGRQYALSWV
CCCCCEEEECCCCCCEEEEEEECCCCCHHHHHHHHHCCCEEEECCCHHHHHHHHHHHHHH
ATLTSEAPENSNYGIGSALVVRANSPYQTLDDVAGLPMAAVAEKAFGGYLTLRYQVIEQG
HHHHHCCCCCCCCCCCCEEEEECCCCHHHHHHHCCCCHHHHHHHHCCCHHEEHHHHHHCC
LNPNDFFADVRYLGFPIDASLYQLRDQTIEAAVVPACLKEQMENEGLIEQGQLRVLNPLN
CCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCC
EPQTQCEVSTPLYPNWSFAKTERGSSQLAKQISRALLAMPADNPAAIAAKASGWTSPVSL
CCCCCEEECCCCCCCCCCHHCCCCHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCHHHH
LSIDKLYQAMDLHPLQQPWWKDALRWLRAHQEWAWALFLFVIVLNIYHFWLEYRFSKSKQ
HHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALEQTQQRLKEKSELLEHSQRVAIVGELGSSLAHELNQPLAAIRNYSEGVLLRLAKNRPN
HHHHHHHHHHHHHHHHHHHCCEEEHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCC
QEIVPVLEKIQRQVERADAIVSRLRNLIKKRSVAISKFDLPQLISDTLELMQFRLQKQMV
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
EVVCSSEGQQHPIEADMVGLQQVLVNVINNAIDACVSYAKLHPEQYSSKIAIHTDFATQG
HHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHCCEEEEEECCCCCC
VTIRILDNGTGLKQENPTEAFVSSKQEGLGLGLSICRDVLEMHGGEFTIQSSNPHGCLVE
EEEEEEECCCCCCCCCCHHHHHCCCCCCCCCCHHHHHHHHHHCCCEEEEECCCCCCCHHH
LCLPYQAVPSLSKNAMSTPNAATDSTNSTKGTRNEW
HHCCHHHHCCHHHHCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8455557 [H]