Click here to switch to the map view.

The map label for this gene is ureR [H]

Identifier: 37680403

GI number: 37680403

Start: 2236597

End: 2237328

Strand: Direct

Name: ureR [H]

Synonym: VV2219

Alternate gene names: 37680403

Gene position: 2236597-2237328 (Clockwise)

Preceding gene: 37680402

Following gene: 37680407

Centisome position: 66.67

GC content: 26.91

Gene sequence:

>732_bases
ATGATAAAGAAAAGGAAATTTAAAGAGTTCCAAGGAAAATCTGTATACTTAAAAATAAGATGCTACAGAAACCACATTAT
CTCCTTCAATTCAAATGGAAATATTTCACACAAAGGGTTTATTGAATCAATAACTCCTGGAAAAGCATATTTAATACCTA
AGGAAACTGAAATTTATGTATATTTATTCCATCGTATTTCAAAGAAAAATATATCTATTTATATCTATACATACGAAAAA
CCTGGGTACCAAGAATTATATAACCTCGTAGCAAAGACCATAAACAAATTAAATAATTTAAACAACATAGAAATACAAAA
TAAAAATTACATATCACAATCTATAAAACATCACCTGCTCAGTGAAATAAAAAAACACTCTACTAATAAAACCCCAAAAA
AAAACCGAAAAGAATATAACAAAAATATAGTAGAAATAATCAACTCAGACATAAAGAAAAAATGGAATTACAAAGAGATA
TGCTCACTCCTCTTTGTGTCTCACTCAACACTATATAGAACATTAAAAAACGAAGGGAAAACACTTAAAATGATTGTTCT
TCATATAAGGATAATAAATTCTCAAAAGCTCCTTGTTAACACGAATATGTCTATCAATGAAATATCCAATAGATGTGGAT
TCAATAGCCCATCATATTTTTCCCGAAAATTTAAAGATAGTGTTAAAATGTCTCCTACAGAATATCGGAGAATGAATAAA
AAATTAGATTAA

Upstream 100 bases:

>100_bases
CAGGAGAGATTAGTTAGATTGTCTGGTTCACTATCTCAAGGGTACTTTCATTCATATCCTGAAAAATGGTCAAAACACTT
ATCAAGTCAAGGATACAAAC

Downstream 100 bases:

>100_bases
TAATAGCAATTTACAACATCTCATGTATGATGGACGTCAAATGATGCTTTTGTACTAATTGGATAGTACGAGGAAATAAT
ATCATGGAAATGTCGATTAA

Product: AraC-type DNA-binding domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 243; Mature: 243

Protein sequence:

>243_residues
MIKKRKFKEFQGKSVYLKIRCYRNHIISFNSNGNISHKGFIESITPGKAYLIPKETEIYVYLFHRISKKNISIYIYTYEK
PGYQELYNLVAKTINKLNNLNNIEIQNKNYISQSIKHHLLSEIKKHSTNKTPKKNRKEYNKNIVEIINSDIKKKWNYKEI
CSLLFVSHSTLYRTLKNEGKTLKMIVLHIRIINSQKLLVNTNMSINEISNRCGFNSPSYFSRKFKDSVKMSPTEYRRMNK
KLD

Sequences:

>Translated_243_residues
MIKKRKFKEFQGKSVYLKIRCYRNHIISFNSNGNISHKGFIESITPGKAYLIPKETEIYVYLFHRISKKNISIYIYTYEK
PGYQELYNLVAKTINKLNNLNNIEIQNKNYISQSIKHHLLSEIKKHSTNKTPKKNRKEYNKNIVEIINSDIKKKWNYKEI
CSLLFVSHSTLYRTLKNEGKTLKMIVLHIRIINSQKLLVNTNMSINEISNRCGFNSPSYFSRKFKDSVKMSPTEYRRMNK
KLD
>Mature_243_residues
MIKKRKFKEFQGKSVYLKIRCYRNHIISFNSNGNISHKGFIESITPGKAYLIPKETEIYVYLFHRISKKNISIYIYTYEK
PGYQELYNLVAKTINKLNNLNNIEIQNKNYISQSIKHHLLSEIKKHSTNKTPKKNRKEYNKNIVEIINSDIKKKWNYKEI
CSLLFVSHSTLYRTLKNEGKTLKMIVLHIRIINSQKLLVNTNMSINEISNRCGFNSPSYFSRKFKDSVKMSPTEYRRMNK
KLD

Specific function: Positive regulator of the expression of the urease operon [H]

COG id: COG2207

COG function: function code K; AraC-type DNA-binding domain-containing proteins

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH araC/xylS-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786776, Length=112, Percent_Identity=32.1428571428571, Blast_Score=71, Evalue=7e-14,
Organism=Escherichia coli, GI1790557, Length=100, Percent_Identity=35, Blast_Score=62, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009057
- InterPro:   IPR012287
- InterPro:   IPR018062
- InterPro:   IPR020449
- InterPro:   IPR018060 [H]

Pfam domain/function: PF00165 HTH_AraC [H]

EC number: NA

Molecular weight: Translated: 28873; Mature: 28873

Theoretical pI: Translated: 10.59; Mature: 10.59

Prosite motif: PS00041 HTH_ARAC_FAMILY_1 ; PS01124 HTH_ARAC_FAMILY_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKKRKFKEFQGKSVYLKIRCYRNHIISFNSNGNISHKGFIESITPGKAYLIPKETEIYV
CCCCCHHHHCCCCEEEEEEEEEECEEEEECCCCCCCCCCCCCCCCCCCEEEECCCCEEEE
YLFHRISKKNISIYIYTYEKPGYQELYNLVAKTINKLNNLNNIEIQNKNYISQSIKHHLL
EEEEHHCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHCCCCCEEECCCHHHHHHHHHHHH
SEIKKHSTNKTPKKNRKEYNKNIVEIINSDIKKKWNYKEICSLLFVSHSTLYRTLKNEGK
HHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCC
TLKMIVLHIRIINSQKLLVNTNMSINEISNRCGFNSPSYFSRKFKDSVKMSPTEYRRMNK
EEEEEEEEEEEECCCEEEEECCCCHHHHHHHCCCCCCHHHHHHHHHCCCCCHHHHHHHHC
KLD
CCC
>Mature Secondary Structure
MIKKRKFKEFQGKSVYLKIRCYRNHIISFNSNGNISHKGFIESITPGKAYLIPKETEIYV
CCCCCHHHHCCCCEEEEEEEEEECEEEEECCCCCCCCCCCCCCCCCCCEEEECCCCEEEE
YLFHRISKKNISIYIYTYEKPGYQELYNLVAKTINKLNNLNNIEIQNKNYISQSIKHHLL
EEEEHHCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHCCCCCEEECCCHHHHHHHHHHHH
SEIKKHSTNKTPKKNRKEYNKNIVEIINSDIKKKWNYKEICSLLFVSHSTLYRTLKNEGK
HHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCC
TLKMIVLHIRIINSQKLLVNTNMSINEISNRCGFNSPSYFSRKFKDSVKMSPTEYRRMNK
EEEEEEEEEEEECCCEEEEECCCCHHHHHHHCCCCCCHHHHHHHHHCCCCCHHHHHHHHC
KLD
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7678244 [H]