Click here to switch to the map view.

The map label for this gene is dsbB

Identifier: 37680308

GI number: 37680308

Start: 2133894

End: 2134412

Strand: Direct

Name: dsbB

Synonym: VV2124

Alternate gene names: 37680308

Gene position: 2133894-2134412 (Clockwise)

Preceding gene: 37680307

Following gene: 37680310

Centisome position: 63.61

GC content: 46.05

Gene sequence:

>519_bases
GTGAATTTATTTGCATCACTCAATCAGTTTTCAAAAAACAGAATCTCATGGCTGCTATTGCTACTCTTCGTGGTCTTTTT
TGAGGGAGCAGCGCTGTTCTTTCAGCATGTGATGATGCTGTCACCCTGTGTGATGTGTATTTATGAACGCGTGGCGATGC
TTGGCGTGGGTGGCGCGGCACTCTTTGGCCTGATTGCACCCAATAACCCACTTGTTCGTTGGTTAGGTTTGGCGGCTTGG
GGAGCCAGTGCTTACAAAGGGTTGGCGTTGTCATTACAACACGTTGATTACCAGTTTAATCCATCGCCTTTTGCTACTTG
TGATCTGTTCGTCACCTTCCCAGATTGGGCTCCACTGAATCAATGGGCGCCTTGGATGTTTGAAGCCTATGGTGACTGTA
GCAAAATCGTATGGCAGTTCATGACACTTTCGATGCCACAATGGTTGGTGATTATTTTTGCTGGCAACCTAGTGGCGCTC
GCATTTATCGTTATTGCTCAGTTTTTCAAATCAAAATAG

Upstream 100 bases:

>100_bases
CGGCGGACATTAAATTTTTAGTTTGCTAAAGAAACTTATCCGAGATAAAAAGCTCTGAGTATTCAGAGCTTTTTTATTGA
ACATACAAAGGATTTTAGAA

Downstream 100 bases:

>100_bases
TTCCGACGCTGACTCGGATTGCAGTTAAAAAAACAGCCGACTCATTCAGAGTCGGCTGTTTTTTGTCGCGTGTTGATTAT
TGGCCACAACACTGTTTGAA

Product: disulfide bond formation protein B

Products: NA

Alternate protein names: Disulfide oxidoreductase

Number of amino acids: Translated: 172; Mature: 172

Protein sequence:

>172_residues
MNLFASLNQFSKNRISWLLLLLFVVFFEGAALFFQHVMMLSPCVMCIYERVAMLGVGGAALFGLIAPNNPLVRWLGLAAW
GASAYKGLALSLQHVDYQFNPSPFATCDLFVTFPDWAPLNQWAPWMFEAYGDCSKIVWQFMTLSMPQWLVIIFAGNLVAL
AFIVIAQFFKSK

Sequences:

>Translated_172_residues
MNLFASLNQFSKNRISWLLLLLFVVFFEGAALFFQHVMMLSPCVMCIYERVAMLGVGGAALFGLIAPNNPLVRWLGLAAW
GASAYKGLALSLQHVDYQFNPSPFATCDLFVTFPDWAPLNQWAPWMFEAYGDCSKIVWQFMTLSMPQWLVIIFAGNLVAL
AFIVIAQFFKSK
>Mature_172_residues
MNLFASLNQFSKNRISWLLLLLFVVFFEGAALFFQHVMMLSPCVMCIYERVAMLGVGGAALFGLIAPNNPLVRWLGLAAW
GASAYKGLALSLQHVDYQFNPSPFATCDLFVTFPDWAPLNQWAPWMFEAYGDCSKIVWQFMTLSMPQWLVIIFAGNLVAL
AFIVIAQFFKSK

Specific function: Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein

COG id: COG1495

COG function: function code O; Disulfide bond formation protein DsbB

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DsbB family

Homologues:

Organism=Escherichia coli, GI1787433, Length=166, Percent_Identity=50.6024096385542, Blast_Score=174, Evalue=3e-45,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DSBB_VIBVU (P59347)

Other databases:

- EMBL:   AE016795
- RefSeq:   NP_761084.2
- ProteinModelPortal:   P59347
- SMR:   P59347
- GeneID:   1179112
- GenomeReviews:   AE016795_GR
- KEGG:   vvu:VV1_2231
- HOGENOM:   HBG637909
- OMA:   ALYFQHV
- ProtClustDB:   PRK01749
- BioCyc:   VVUL216895:VV1_2231-MONOMER
- GO:   GO:0006810
- HAMAP:   MF_00286
- InterPro:   IPR003752
- InterPro:   IPR022920

Pfam domain/function: PF02600 DsbB

EC number: NA

Molecular weight: Translated: 19391; Mature: 19391

Theoretical pI: Translated: 7.94; Mature: 7.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x199c45d0)-; HASH(0x196762f8)-; HASH(0x195491ac)-; HASH(0x1965bf0c)-;

Cys/Met content:

2.3 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
7.0 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
4.7 %Met     (Mature Protein)
7.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLFASLNQFSKNRISWLLLLLFVVFFEGAALFFQHVMMLSPCVMCIYERVAMLGVGGAA
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
LFGLIAPNNPLVRWLGLAAWGASAYKGLALSLQHVDYQFNPSPFATCDLFVTFPDWAPLN
HHHHCCCCCHHHHHHHHHHHCHHHHHHHHHHHHHCCEEECCCCCCEEEEEEECCCCCCCC
QWAPWMFEAYGDCSKIVWQFMTLSMPQWLVIIFAGNLVALAFIVIAQFFKSK
CCCHHHHHHHCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCH
>Mature Secondary Structure
MNLFASLNQFSKNRISWLLLLLFVVFFEGAALFFQHVMMLSPCVMCIYERVAMLGVGGAA
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
LFGLIAPNNPLVRWLGLAAWGASAYKGLALSLQHVDYQFNPSPFATCDLFVTFPDWAPLN
HHHHCCCCCHHHHHHHHHHHCHHHHHHHHHHHHHCCEEECCCCCCEEEEEEECCCCCCCC
QWAPWMFEAYGDCSKIVWQFMTLSMPQWLVIIFAGNLVALAFIVIAQFFKSK
CCCHHHHHHHCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA