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The map label for this gene is fmt2 [H]

Identifier: 34498273

GI number: 34498273

Start: 3068462

End: 3069322

Strand: Reverse

Name: fmt2 [H]

Synonym: CV_2818

Alternate gene names: 34498273

Gene position: 3069322-3068462 (Counterclockwise)

Preceding gene: 34498274

Following gene: 34498272

Centisome position: 64.6

GC content: 66.55

Gene sequence:

>861_bases
ATGCGTTTCGCGATTACGCTTTCCGATCGTTTCAAACCAGTGCTGGACGTGTTCCTGCAGGCCGGCTGGCAGCCGCTGAA
GGTGTTCTGCACGCCGGTGGACCACCGGATGCACCACAACAAGCTGTCGGTGGCCTTCGCAGAGCAGCGCAAGCTGCCGC
TGCAGCTGTCGCCGCTGCGGACGCATGATCTGGCGGAACTGGCCGAGCAGGGCTGCGAGGCGCTGCTGGTGGGCAGCTAC
AATTGGCGCATTCCCGACTGGACGTCCTACCTGAAGTACGCGGTCAATTTCCATCCTTCGCCACTGCCGCTGGGCCGCGG
GCCGTATCCGCAGGTGCGCGCGCTGCTGGACGGGCATCGGGAGTGGGCCTGCACCTGCCACAAGGTGGGCCCGGATTTCG
ACGCCGGGGACATCCTGGATCAGGAGCGGTTTCCGCTGGGCGAGGCCGACAGCCACCAGATGCTGGATATCAAGCTGCAG
CTGGCCTTGCATAGGCTGAGCCACCGGCTGGCGCATGATTTCGACCGCCTGTGGCGCGACGCCAGGCCGCAGGGCGAGGG
CGGCAGCTACTGGCCGCTGTGGACCGATCACGACCGGATGCTGGATTTCAGCCGCACCACGGCGGAGCTGCTGCGCCAGG
TGCGGGCCTTCGGCGATTTCGAGTGCGCGGCGGTGGTCAACAACGTCACCTTCTTCGTCCACCGCGCCGAGGGCTGGACC
GAGACGCACAATTTCGCGCCGGGCAGCCTGATCTATTCCCAGGCCGAGCAATTGCTGGTGGCCACGGCGGACGGCATGCT
GCTGATCAGCGAGTGGAGCCTGTACGGGCCGGATGCGGTGACGGGGCGGGGCAGGCGCTGA

Upstream 100 bases:

>100_bases
CCTTCTGTTAATTTGCGTGTCATCGCCGCGGAGGCGGGAGGCTCGGATGGTATAACCAAGGCACCGGGCCGGAAGGGCCC
GCTTGCCGCGAGTGGATGCC

Downstream 100 bases:

>100_bases
CCAGCGCGCACAAAGAAAATTCTAACTGTTTGGCATGTTTGTGGCGCGGATGACGCGGGATTGTCCTGCGCTTGGTCGAT
TGATTGACCGGAGCGCGCGA

Product: methionyl-tRNA formyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 286; Mature: 286

Protein sequence:

>286_residues
MRFAITLSDRFKPVLDVFLQAGWQPLKVFCTPVDHRMHHNKLSVAFAEQRKLPLQLSPLRTHDLAELAEQGCEALLVGSY
NWRIPDWTSYLKYAVNFHPSPLPLGRGPYPQVRALLDGHREWACTCHKVGPDFDAGDILDQERFPLGEADSHQMLDIKLQ
LALHRLSHRLAHDFDRLWRDARPQGEGGSYWPLWTDHDRMLDFSRTTAELLRQVRAFGDFECAAVVNNVTFFVHRAEGWT
ETHNFAPGSLIYSQAEQLLVATADGMLLISEWSLYGPDAVTGRGRR

Sequences:

>Translated_286_residues
MRFAITLSDRFKPVLDVFLQAGWQPLKVFCTPVDHRMHHNKLSVAFAEQRKLPLQLSPLRTHDLAELAEQGCEALLVGSY
NWRIPDWTSYLKYAVNFHPSPLPLGRGPYPQVRALLDGHREWACTCHKVGPDFDAGDILDQERFPLGEADSHQMLDIKLQ
LALHRLSHRLAHDFDRLWRDARPQGEGGSYWPLWTDHDRMLDFSRTTAELLRQVRAFGDFECAAVVNNVTFFVHRAEGWT
ETHNFAPGSLIYSQAEQLLVATADGMLLISEWSLYGPDAVTGRGRR
>Mature_286_residues
MRFAITLSDRFKPVLDVFLQAGWQPLKVFCTPVDHRMHHNKLSVAFAEQRKLPLQLSPLRTHDLAELAEQGCEALLVGSY
NWRIPDWTSYLKYAVNFHPSPLPLGRGPYPQVRALLDGHREWACTCHKVGPDFDAGDILDQERFPLGEADSHQMLDIKLQ
LALHRLSHRLAHDFDRLWRDARPQGEGGSYWPLWTDHDRMLDFSRTTAELLRQVRAFGDFECAAVVNNVTFFVHRAEGWT
ETHNFAPGSLIYSQAEQLLVATADGMLLISEWSLYGPDAVTGRGRR

Specific function: Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by:(I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-

COG id: COG0223

COG function: function code J; Methionyl-tRNA formyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fmt family [H]

Homologues:

None

Paralogues:

None

Copy number: 400 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005794
- InterPro:   IPR005793
- InterPro:   IPR002376
- InterPro:   IPR011034
- InterPro:   IPR015518 [H]

Pfam domain/function: PF02911 Formyl_trans_C; PF00551 Formyl_trans_N [H]

EC number: =2.1.2.9 [H]

Molecular weight: Translated: 32697; Mature: 32697

Theoretical pI: Translated: 6.75; Mature: 6.75

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRFAITLSDRFKPVLDVFLQAGWQPLKVFCTPVDHRMHHNKLSVAFAEQRKLPLQLSPLR
CEEEEEECCCCHHHHHHHHHCCCEEEEEEECCHHHHHCCCCEEEEEHHCCCCCEEECCCC
THDLAELAEQGCEALLVGSYNWRIPDWTSYLKYAVNFHPSPLPLGRGPYPQVRALLDGHR
HHHHHHHHHCCCCEEEECCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHCCCC
EWACTCHKVGPDFDAGDILDQERFPLGEADSHQMLDIKLQLALHRLSHRLAHDFDRLWRD
CEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHH
ARPQGEGGSYWPLWTDHDRMLDFSRTTAELLRQVRAFGDFECAAVVNNVTFFVHRAEGWT
CCCCCCCCCCCCEECCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCEEEEEECCCCCC
ETHNFAPGSLIYSQAEQLLVATADGMLLISEWSLYGPDAVTGRGRR
CCCCCCCCHHHHHHHHHEEEEECCCEEEEEECCCCCCCCCCCCCCC
>Mature Secondary Structure
MRFAITLSDRFKPVLDVFLQAGWQPLKVFCTPVDHRMHHNKLSVAFAEQRKLPLQLSPLR
CEEEEEECCCCHHHHHHHHHCCCEEEEEEECCHHHHHCCCCEEEEEHHCCCCCEEECCCC
THDLAELAEQGCEALLVGSYNWRIPDWTSYLKYAVNFHPSPLPLGRGPYPQVRALLDGHR
HHHHHHHHHCCCCEEEECCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHCCCC
EWACTCHKVGPDFDAGDILDQERFPLGEADSHQMLDIKLQLALHRLSHRLAHDFDRLWRD
CEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHH
ARPQGEGGSYWPLWTDHDRMLDFSRTTAELLRQVRAFGDFECAAVVNNVTFFVHRAEGWT
CCCCCCCCCCCCEECCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCEEEEEECCCCCC
ETHNFAPGSLIYSQAEQLLVATADGMLLISEWSLYGPDAVTGRGRR
CCCCCCCCHHHHHHHHHEEEEECCCEEEEEECCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA