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The map label for this gene is trpF [H]

Identifier: 34498218

GI number: 34498218

Start: 2999192

End: 2999812

Strand: Reverse

Name: trpF [H]

Synonym: CV_2763

Alternate gene names: 34498218

Gene position: 2999812-2999192 (Counterclockwise)

Preceding gene: 34498219

Following gene: 161594051

Centisome position: 63.14

GC content: 66.51

Gene sequence:

>621_bases
GTGGTCAGAATCAAAGTTTGTGGCATCACCAGGCCGGAAGACGGCGCAGAGGCGGCCCGCTTGGGCGCGGACGCCGTCGG
GCTGGTGTTTTACGGCAAGAGCCCCCGCAACGTGTCCATAGAGCAGGCGCGCGCGGTGATCGCCGCGCTGCCGCCTTTCG
TCAGCGTGGTGGCCCTGTTCGTCAACCCGGAGCGCGAGTGGGTGGAGCAGGTGCTGGCGGGCTGCGCCGTAGACGTGCTG
CAATTCCACGGCGAAGAGAGCGCCGAGTTCTGCCGCTCTTTCCACCGGCCCTATCTGAAGGCCGTCAGGGTGAGGCCGGG
CGTGGATCTGCTGGAATCGGCGCGTCGCTATCCGGATGCGCGCGGCCTGTTGACCGACGCCTTCGTCGAAGGGGCCCACG
GCGGCACCGGCACCACCTTCGACTGGGCGCTATTGCCGCACGATTTGCCGCTGCCGCTGATTTTGTCCGGCGGCCTGGAC
GAAAAGAACATCGCCGAAGCCGTGCGCCGGGTGAGGCCGGCCGCGGTTGACGTCTCCAGCGGAGTGGAGGCGGGCAAGGG
AATCAAAGACGCCGCCAGGATGGCGGCCTTCATATCAGGAGCAAGACATGGATCGGTATGA

Upstream 100 bases:

>100_bases
GTCGGTTATCCGGATGAGTTTTCCCTGCCGTCCCGCTGCGAGGCGGCGCGGCTCAGATTGCGCTGAAATGCAACGCTTTA
TAGGGCGAACATAGAAAATC

Downstream 100 bases:

>100_bases
TTTTCCGGATGCGCAGGGCCATTTCGGCCCTTACGGCGGGGTCTACGTCGCCGAAACCTTGATGGTGGCGCTGGACCAGC
TGAAAGAAGAGTACGCCCGA

Product: phosphoribosylanthranilate isomerase

Products: NA

Alternate protein names: PRAI [H]

Number of amino acids: Translated: 206; Mature: 206

Protein sequence:

>206_residues
MVRIKVCGITRPEDGAEAARLGADAVGLVFYGKSPRNVSIEQARAVIAALPPFVSVVALFVNPEREWVEQVLAGCAVDVL
QFHGEESAEFCRSFHRPYLKAVRVRPGVDLLESARRYPDARGLLTDAFVEGAHGGTGTTFDWALLPHDLPLPLILSGGLD
EKNIAEAVRRVRPAAVDVSSGVEAGKGIKDAARMAAFISGARHGSV

Sequences:

>Translated_206_residues
MVRIKVCGITRPEDGAEAARLGADAVGLVFYGKSPRNVSIEQARAVIAALPPFVSVVALFVNPEREWVEQVLAGCAVDVL
QFHGEESAEFCRSFHRPYLKAVRVRPGVDLLESARRYPDARGLLTDAFVEGAHGGTGTTFDWALLPHDLPLPLILSGGLD
EKNIAEAVRRVRPAAVDVSSGVEAGKGIKDAARMAAFISGARHGSV
>Mature_206_residues
MVRIKVCGITRPEDGAEAARLGADAVGLVFYGKSPRNVSIEQARAVIAALPPFVSVVALFVNPEREWVEQVLAGCAVDVL
QFHGEESAEFCRSFHRPYLKAVRVRPGVDLLESARRYPDARGLLTDAFVEGAHGGTGTTFDWALLPHDLPLPLILSGGLD
EKNIAEAVRRVRPAAVDVSSGVEAGKGIKDAARMAAFISGARHGSV

Specific function: Bifunctional Enzyme That Catalyzes Two Sequential Steps Of Tryptophan Biosynthetic Pathway. The First Reaction Is Catalyzed By The Isomerase, Coded By The Trpf Domain; The Second Reaction Is Catalyzed By The Synthase, Coded By The Trpc Domain. [C]

COG id: COG0135

COG function: function code E; Phosphoribosylanthranilate isomerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the trpF family [H]

Homologues:

Organism=Escherichia coli, GI87081863, Length=200, Percent_Identity=32, Blast_Score=85, Evalue=3e-18,
Organism=Saccharomyces cerevisiae, GI6320210, Length=215, Percent_Identity=27.906976744186, Blast_Score=72, Evalue=9e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR001240
- InterPro:   IPR011060 [H]

Pfam domain/function: PF00697 PRAI [H]

EC number: =5.3.1.24 [H]

Molecular weight: Translated: 21995; Mature: 21995

Theoretical pI: Translated: 7.05; Mature: 7.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVRIKVCGITRPEDGAEAARLGADAVGLVFYGKSPRNVSIEQARAVIAALPPFVSVVALF
CEEEEEECCCCCCCCHHHHHHCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHH
VNPEREWVEQVLAGCAVDVLQFHGEESAEFCRSFHRPYLKAVRVRPGVDLLESARRYPDA
CCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCC
RGLLTDAFVEGAHGGTGTTFDWALLPHDLPLPLILSGGLDEKNIAEAVRRVRPAAVDVSS
CCHHHHHHHHCCCCCCCCEEEEEECCCCCCCCEEEECCCCHHHHHHHHHHHCCHHCCCCC
GVEAGKGIKDAARMAAFISGARHGSV
CCCCCCCHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MVRIKVCGITRPEDGAEAARLGADAVGLVFYGKSPRNVSIEQARAVIAALPPFVSVVALF
CEEEEEECCCCCCCCHHHHHHCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHH
VNPEREWVEQVLAGCAVDVLQFHGEESAEFCRSFHRPYLKAVRVRPGVDLLESARRYPDA
CCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCC
RGLLTDAFVEGAHGGTGTTFDWALLPHDLPLPLILSGGLDEKNIAEAVRRVRPAAVDVSS
CCHHHHHHHHCCCCCCCCEEEEEECCCCCCCCEEEECCCCHHHHHHHHHHHCCHHCCCCC
GVEAGKGIKDAARMAAFISGARHGSV
CCCCCCCHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA