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The map label for this gene is aspC [H]

Identifier: 33863300

GI number: 33863300

Start: 1107069

End: 1108283

Strand: Reverse

Name: aspC [H]

Synonym: PMT1029

Alternate gene names: 33863300

Gene position: 1108283-1107069 (Counterclockwise)

Preceding gene: 33863304

Following gene: 33863299

Centisome position: 45.97

GC content: 48.48

Gene sequence:

>1215_bases
GTGAACTCTTTTTCCTCAAGCAAACACCCTCAACCTGGCACGCAGATTGATGCTGTGCTGGATCCTGTGATTCCAGCACT
TAACGAGTTGGTGGCGAAGACGCCAGGGACCCTTTCGCTGGCCCAGGGCATGGTGAATTGGCCTCCACCCATTGCCGTAA
AACTGGCAATGAACAATGCTCTGTTGAATCAAGAATCAAGTCTCAATCGTTATGGCCCGGCTCGAGGTGATCCTGATCTG
CTTGAGCTAATTAAGCAAAAATTGATGATGCAGAACGGTTTGGATTTGGCCGAAAGCATGGTCATGGTCACTGCAGGTAG
CAACATGGCATTTCATGCCATTGCTCAGGTTCTCTGTGACCCTGGCGATGAGGTCATTCTGCCGCTGCCTTATTACTTTA
ATCACTTTATGGCTATTCAGTTGGCCGGTGGAGTGCCTGTGCCTGTGAATGCTGGTTTAATACCTAACCCTGGACTCATA
GAGGCTGCGATTACAAAACGCACCCGTGCCATTGTCACGATAAGTCCTAATAACCCAAGCGGAATCGTTTTCCCTCAAAC
CTTACTTGCTGCCATCAATCGGATCTGTGCCCAGCATGGTTTGCTGCACATCAGCGATGAAGCTTATGAGGATTTTGTGT
TTGGTGATGTACCTCATTGGAGCCCTGGATCTCTTCCTGGCGCAGGGAACCATACTGTTTCGCTCTATTCGTTCTCCAAG
GCCTATGGCATGGCCGGATGGCGTCTTGGTTATATGTCTGTTCCTATTGTCTGGAGTAAGGCTTTGGAGAAGGTTCAAGA
CACAGTCTTGATCTGTCCACCTCGTTTTTGCCAACGAGCAGCGATTGCGGCCTTGTTAGATGGTTCTGATTGGGTGCGTC
AGAATGTGTCTCAATTGATGAGTCGATATCAGTTGCTCTTGAAGCGTTTTGCAGCTAGTAACGATCGACCCTGGCGCTTT
TTACATGAACCCAATGGAGCTTTTTATTGCTTACTTGAAGTGGATTGTGGTTGCAATGGAGACACCTTGATGCGTCAGCT
GGTAAGAGATTATCGAGTTGCCACGATTGGAGGTTGTAGTTTTGGGTTTAAGAACGAGAGTTGTGTACTGCGCATCAGTG
TGGGGATGCTTGAAGGCGCTGAATTGATAGATGCCTTTAATCGCTTGGAGGCAGGCATGCTTAATGCTGTTCAACAAGGA
GACCGTACCACCTGA

Upstream 100 bases:

>100_bases
TTTTTCTTCTCTTTTGGCTGGCCCATATCTTATGGATTTGGTTATTTGAGATTTCCATTCCATTCTGGTAAATAATGGAC
GAACCTTTAACTTGATCGAC

Downstream 100 bases:

>100_bases
ATAATAAAGTTAATTCCAATTTATTCTTTTATTTTATTGAAAATAGCAATCAGCACTTGTTGAGTAATGACTGCGTGGTA
AGTTTTGATCAGATCCGCAG

Product: aspartate aminotransferase

Products: NA

Alternate protein names: AspAT; Transaminase A [H]

Number of amino acids: Translated: 404; Mature: 404

Protein sequence:

>404_residues
MNSFSSSKHPQPGTQIDAVLDPVIPALNELVAKTPGTLSLAQGMVNWPPPIAVKLAMNNALLNQESSLNRYGPARGDPDL
LELIKQKLMMQNGLDLAESMVMVTAGSNMAFHAIAQVLCDPGDEVILPLPYYFNHFMAIQLAGGVPVPVNAGLIPNPGLI
EAAITKRTRAIVTISPNNPSGIVFPQTLLAAINRICAQHGLLHISDEAYEDFVFGDVPHWSPGSLPGAGNHTVSLYSFSK
AYGMAGWRLGYMSVPIVWSKALEKVQDTVLICPPRFCQRAAIAALLDGSDWVRQNVSQLMSRYQLLLKRFAASNDRPWRF
LHEPNGAFYCLLEVDCGCNGDTLMRQLVRDYRVATIGGCSFGFKNESCVLRISVGMLEGAELIDAFNRLEAGMLNAVQQG
DRTT

Sequences:

>Translated_404_residues
MNSFSSSKHPQPGTQIDAVLDPVIPALNELVAKTPGTLSLAQGMVNWPPPIAVKLAMNNALLNQESSLNRYGPARGDPDL
LELIKQKLMMQNGLDLAESMVMVTAGSNMAFHAIAQVLCDPGDEVILPLPYYFNHFMAIQLAGGVPVPVNAGLIPNPGLI
EAAITKRTRAIVTISPNNPSGIVFPQTLLAAINRICAQHGLLHISDEAYEDFVFGDVPHWSPGSLPGAGNHTVSLYSFSK
AYGMAGWRLGYMSVPIVWSKALEKVQDTVLICPPRFCQRAAIAALLDGSDWVRQNVSQLMSRYQLLLKRFAASNDRPWRF
LHEPNGAFYCLLEVDCGCNGDTLMRQLVRDYRVATIGGCSFGFKNESCVLRISVGMLEGAELIDAFNRLEAGMLNAVQQG
DRTT
>Mature_404_residues
MNSFSSSKHPQPGTQIDAVLDPVIPALNELVAKTPGTLSLAQGMVNWPPPIAVKLAMNNALLNQESSLNRYGPARGDPDL
LELIKQKLMMQNGLDLAESMVMVTAGSNMAFHAIAQVLCDPGDEVILPLPYYFNHFMAIQLAGGVPVPVNAGLIPNPGLI
EAAITKRTRAIVTISPNNPSGIVFPQTLLAAINRICAQHGLLHISDEAYEDFVFGDVPHWSPGSLPGAGNHTVSLYSFSK
AYGMAGWRLGYMSVPIVWSKALEKVQDTVLICPPRFCQRAAIAALLDGSDWVRQNVSQLMSRYQLLLKRFAASNDRPWRF
LHEPNGAFYCLLEVDCGCNGDTLMRQLVRDYRVATIGGCSFGFKNESCVLRISVGMLEGAELIDAFNRLEAGMLNAVQQG
DRTT

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI56713254, Length=328, Percent_Identity=27.7439024390244, Blast_Score=115, Evalue=8e-26,
Organism=Homo sapiens, GI56713256, Length=328, Percent_Identity=27.7439024390244, Blast_Score=115, Evalue=1e-25,
Organism=Homo sapiens, GI95147551, Length=296, Percent_Identity=28.3783783783784, Blast_Score=110, Evalue=2e-24,
Organism=Homo sapiens, GI169881279, Length=296, Percent_Identity=28.3783783783784, Blast_Score=110, Evalue=2e-24,
Organism=Homo sapiens, GI169881281, Length=200, Percent_Identity=28.5, Blast_Score=81, Evalue=1e-15,
Organism=Escherichia coli, GI1786816, Length=269, Percent_Identity=31.9702602230483, Blast_Score=102, Evalue=4e-23,
Organism=Escherichia coli, GI1788627, Length=335, Percent_Identity=25.0746268656716, Blast_Score=95, Evalue=9e-21,
Organism=Escherichia coli, GI1788722, Length=334, Percent_Identity=25.1497005988024, Blast_Score=81, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI71994472, Length=281, Percent_Identity=27.0462633451957, Blast_Score=99, Evalue=6e-21,
Organism=Caenorhabditis elegans, GI71994476, Length=281, Percent_Identity=27.0462633451957, Blast_Score=98, Evalue=8e-21,
Organism=Caenorhabditis elegans, GI17567369, Length=249, Percent_Identity=28.5140562248996, Blast_Score=91, Evalue=8e-19,
Organism=Saccharomyces cerevisiae, GI6322401, Length=231, Percent_Identity=31.6017316017316, Blast_Score=102, Evalue=1e-22,
Organism=Drosophila melanogaster, GI28573069, Length=250, Percent_Identity=28, Blast_Score=98, Evalue=9e-21,
Organism=Drosophila melanogaster, GI24646114, Length=250, Percent_Identity=28, Blast_Score=98, Evalue=9e-21,
Organism=Drosophila melanogaster, GI28573067, Length=250, Percent_Identity=28, Blast_Score=98, Evalue=9e-21,
Organism=Drosophila melanogaster, GI28573065, Length=250, Percent_Identity=28, Blast_Score=98, Evalue=9e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.1 [H]

Molecular weight: Translated: 43966; Mature: 43966

Theoretical pI: Translated: 6.50; Mature: 6.50

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNSFSSSKHPQPGTQIDAVLDPVIPALNELVAKTPGTLSLAQGMVNWPPPIAVKLAMNNA
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCCCCCCEEEEEEECHH
LLNQESSLNRYGPARGDPDLLELIKQKLMMQNGLDLAESMVMVTAGSNMAFHAIAQVLCD
HHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHCEEEEEECCCHHHHHHHHHHHC
PGDEVILPLPYYFNHFMAIQLAGGVPVPVNAGLIPNPGLIEAAITKRTRAIVTISPNNPS
CCCCEEEECHHHHCCEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHCCEEEEEECCCCCC
GIVFPQTLLAAINRICAQHGLLHISDEAYEDFVFGDVPHWSPGSLPGAGNHTVSLYSFSK
CEECHHHHHHHHHHHHHHCCCEEECCHHHHHHCCCCCCCCCCCCCCCCCCCEEEEEEEHH
AYGMAGWRLGYMSVPIVWSKALEKVQDTVLICPPRFCQRAAIAALLDGSDWVRQNVSQLM
HHCCCCEEECCEECHHHHHHHHHHHHCCEEECCHHHHHHHHHHHHHCCCHHHHHHHHHHH
SRYQLLLKRFAASNDRPWRFLHEPNGAFYCLLEVDCGCNGDTLMRQLVRDYRVATIGGCS
HHHHHHHHHHHCCCCCCEEEEECCCCCEEEEEEECCCCCHHHHHHHHHHHCCEEEEECCC
FGFKNESCVLRISVGMLEGAELIDAFNRLEAGMLNAVQQGDRTT
CCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MNSFSSSKHPQPGTQIDAVLDPVIPALNELVAKTPGTLSLAQGMVNWPPPIAVKLAMNNA
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCCCCCCEEEEEEECHH
LLNQESSLNRYGPARGDPDLLELIKQKLMMQNGLDLAESMVMVTAGSNMAFHAIAQVLCD
HHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHCEEEEEECCCHHHHHHHHHHHC
PGDEVILPLPYYFNHFMAIQLAGGVPVPVNAGLIPNPGLIEAAITKRTRAIVTISPNNPS
CCCCEEEECHHHHCCEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHCCEEEEEECCCCCC
GIVFPQTLLAAINRICAQHGLLHISDEAYEDFVFGDVPHWSPGSLPGAGNHTVSLYSFSK
CEECHHHHHHHHHHHHHHCCCEEECCHHHHHHCCCCCCCCCCCCCCCCCCCEEEEEEEHH
AYGMAGWRLGYMSVPIVWSKALEKVQDTVLICPPRFCQRAAIAALLDGSDWVRQNVSQLM
HHCCCCEEECCEECHHHHHHHHHHHHCCEEECCHHHHHHHHHHHHHCCCHHHHHHHHHHH
SRYQLLLKRFAASNDRPWRFLHEPNGAFYCLLEVDCGCNGDTLMRQLVRDYRVATIGGCS
HHHHHHHHHHHCCCCCCEEEEECCCCCEEEEEEECCCCCHHHHHHHHHHHCCEEEEECCC
FGFKNESCVLRISVGMLEGAELIDAFNRLEAGMLNAVQQGDRTT
CCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9537320 [H]