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The map label for this gene is fur [C]

Identifier: 33862794

GI number: 33862794

Start: 570152

End: 570616

Strand: Direct

Name: fur [C]

Synonym: PMT0521

Alternate gene names: 33862794

Gene position: 570152-570616 (Clockwise)

Preceding gene: 33862793

Following gene: 33862795

Centisome position: 23.65

GC content: 53.33

Gene sequence:

>465_bases
ATGCACACCGCTCCCAAGATCAGCGGCTCAAGTGCTGAGCGGGATGAAGATGGAGTGCAGGGAGCCTTCGAACGCTGCCG
GCAGCTTGGGATGCGACTAAGCCGTCAGCGGCGCATGGTGCTGGATCTCCTCTGGAGTGAAGCCACTCATCTCAGTGCTC
GCGATATCTTTCAAAAGCTCAACACCTGTGGACGGTCCATTGGTCACACATCCGTCTATCAGAACCTGGAGGCACTTCAA
TCAGCAGGACTGATCGAATGTCTCGATCGAGCCAATGGTCGCCTATACAGCTACCGAAGCGATCCTCATAGCCACCTCAC
TTGCATAGAGACCGGCAACATCACAGACCTTGATATAGAACTCCCTGAGGATTTGCTCGATCAAATCGAGGCCAAAACTG
GTTACTGCATTCACTCCTACACCCTTCAACTCAGCGGTCGGCCAGCATGTAATAACCACGACTAA

Upstream 100 bases:

>100_bases
AGGACCCACCAACTAGCAAACCACTGATGGCATGAGGACCTTGGACTATGAATTGACCTTGCTGGAGCCGTAAATTGAAT
TCATTATCACTTCAGTTGTG

Downstream 100 bases:

>100_bases
AAACATCAAGATCTCAACGGACTGGAGGATTTGCCTAACGCTCGTTACCTTGATGGCATAAGCCTTGTGCCGTGGTGAAT
TTGGCGGACAGCACATCCAC

Product: ferric uptake regulator family protein

Products: NA

Alternate protein names: Ferric Uptake Regulator; Ferric Uptake Regulation Protein; Ferric Uptake Regulator Fur Family; FUR Family Transcriptional Regulator; Transcriptional Regulator Fur Family; Transcriptional Regulator Fur Family Protein; Fur Family Ferric Uptake Regulator

Number of amino acids: Translated: 154; Mature: 154

Protein sequence:

>154_residues
MHTAPKISGSSAERDEDGVQGAFERCRQLGMRLSRQRRMVLDLLWSEATHLSARDIFQKLNTCGRSIGHTSVYQNLEALQ
SAGLIECLDRANGRLYSYRSDPHSHLTCIETGNITDLDIELPEDLLDQIEAKTGYCIHSYTLQLSGRPACNNHD

Sequences:

>Translated_154_residues
MHTAPKISGSSAERDEDGVQGAFERCRQLGMRLSRQRRMVLDLLWSEATHLSARDIFQKLNTCGRSIGHTSVYQNLEALQ
SAGLIECLDRANGRLYSYRSDPHSHLTCIETGNITDLDIELPEDLLDQIEAKTGYCIHSYTLQLSGRPACNNHD
>Mature_154_residues
MHTAPKISGSSAERDEDGVQGAFERCRQLGMRLSRQRRMVLDLLWSEATHLSARDIFQKLNTCGRSIGHTSVYQNLEALQ
SAGLIECLDRANGRLYSYRSDPHSHLTCIETGNITDLDIELPEDLLDQIEAKTGYCIHSYTLQLSGRPACNNHD

Specific function: Acts As A Global Negative Controlling Element, Employing Fe(2+) As A Cofactor To Bind The Operator Of The Repressed Genes. Regulates The Expression Of Several Outer-Membrane Proteins Including The Iron Transport Operon. [C]

COG id: COG0735

COG function: function code P; Fe2+/Zn2+ uptake regulation proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: 3432 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 17291; Mature: 17291

Theoretical pI: Translated: 6.14; Mature: 6.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
3.9 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHTAPKISGSSAERDEDGVQGAFERCRQLGMRLSRQRRMVLDLLWSEATHLSARDIFQKL
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
NTCGRSIGHTSVYQNLEALQSAGLIECLDRANGRLYSYRSDPHSHLTCIETGNITDLDIE
HHHHHHCCHHHHHHHHHHHHHCCHHHHHHHCCCCEEEECCCCCCCEEEEECCCEEEEECC
LPEDLLDQIEAKTGYCIHSYTLQLSGRPACNNHD
CCHHHHHHHHHCCCEEEEEEEEEECCCCCCCCCC
>Mature Secondary Structure
MHTAPKISGSSAERDEDGVQGAFERCRQLGMRLSRQRRMVLDLLWSEATHLSARDIFQKL
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
NTCGRSIGHTSVYQNLEALQSAGLIECLDRANGRLYSYRSDPHSHLTCIETGNITDLDIE
HHHHHHCCHHHHHHHHHHHHHCCHHHHHHHCCCCEEEECCCCCCCEEEEECCCEEEEECC
LPEDLLDQIEAKTGYCIHSYTLQLSGRPACNNHD
CCHHHHHHHHHCCCEEEEEEEEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA