Click here to switch to the map view.

The map label for this gene is pgsA [H]

Identifier: 33862791

GI number: 33862791

Start: 567757

End: 568326

Strand: Direct

Name: pgsA [H]

Synonym: PMT0518

Alternate gene names: 33862791

Gene position: 567757-568326 (Clockwise)

Preceding gene: 33862789

Following gene: 33862793

Centisome position: 23.55

GC content: 56.84

Gene sequence:

>570_bases
GTGAGTGCACCATCCCGCCTCGGTTCACCATCAACACTGAGAAGATCGGCAAATGCTCTAACCGTGGGGAGGTCTGTCGC
AGGTCTCCCCCTGGTGTTGTTGCTTCAATTGGGTCAGCCTGCTCTGGCATGGGTGTTGTTGTTGCTGGCAGGGCTTAGCG
ACGCCGCCGATGGCTGGCTGGCCCGCAGAGCTGGTGGTGGTAGCAGCTGGGGCGCTCGCCTGGACCCGCTTGCTGACAAG
CTTCTTCTAGCAGCACCAATGATCTGGCTGGCCAGCAACGAAGCCTTGCCTGTTTGGTCGATCTGGTTACTGCTGGCCAG
GGAACTACTGATTTCCGGTTGGCGTGCTCAAGCCTCATCTGGTGCTCCTGCTTCTTGGGGAGGTAAAGCAAAGACGATCC
TTCAATTCCTAAGCATGCTGCTGTTGTTGTGGCCGCCTAGTTGGGGAAGCCACAACTTTTGCCTAAATATGCAGCACCTG
GGCTGGTGGTTGTTCTGGCCATCTCTGATCCTGGCGTTTAGCTCTGCGGTGGCATACATCAAACCCCGATCAAGGATTGA
TCGGCACTGA

Upstream 100 bases:

>100_bases
GATGTGGCTGGCACGACACTGAGAACCGGCGTTGACATGACATCCTTCACCGTCTGCTGGAGCACCATGAATCACATGCA
AGTTCATTCATTCTGAGCCT

Downstream 100 bases:

>100_bases
AATCTGGTTCAGCCGTTGGCTTCAAGGAGTAGTCGTTGCAGTAGCTATCTTCGAGGCCAGTCTCAAGGTCAAAGCGTGGC
TGCCATGCCAATTCCCGCTC

Product: CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase

Products: NA

Alternate protein names: Phosphatidylglycerophosphate synthase; PGP synthase [H]

Number of amino acids: Translated: 189; Mature: 188

Protein sequence:

>189_residues
MSAPSRLGSPSTLRRSANALTVGRSVAGLPLVLLLQLGQPALAWVLLLLAGLSDAADGWLARRAGGGSSWGARLDPLADK
LLLAAPMIWLASNEALPVWSIWLLLARELLISGWRAQASSGAPASWGGKAKTILQFLSMLLLLWPPSWGSHNFCLNMQHL
GWWLFWPSLILAFSSAVAYIKPRSRIDRH

Sequences:

>Translated_189_residues
MSAPSRLGSPSTLRRSANALTVGRSVAGLPLVLLLQLGQPALAWVLLLLAGLSDAADGWLARRAGGGSSWGARLDPLADK
LLLAAPMIWLASNEALPVWSIWLLLARELLISGWRAQASSGAPASWGGKAKTILQFLSMLLLLWPPSWGSHNFCLNMQHL
GWWLFWPSLILAFSSAVAYIKPRSRIDRH
>Mature_188_residues
SAPSRLGSPSTLRRSANALTVGRSVAGLPLVLLLQLGQPALAWVLLLLAGLSDAADGWLARRAGGGSSWGARLDPLADKL
LLAAPMIWLASNEALPVWSIWLLLARELLISGWRAQASSGAPASWGGKAKTILQFLSMLLLLWPPSWGSHNFCLNMQHLG
WWLFWPSLILAFSSAVAYIKPRSRIDRH

Specific function: This protein catalyzes the committed step to the synthesis of the acidic phospholipids [H]

COG id: COG0558

COG function: function code I; Phosphatidylglycerophosphate synthase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CDP-alcohol phosphatidyltransferase class-I family [H]

Homologues:

Organism=Escherichia coli, GI1788220, Length=141, Percent_Identity=34.0425531914894, Blast_Score=61, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000462
- InterPro:   IPR004570 [H]

Pfam domain/function: PF01066 CDP-OH_P_transf [H]

EC number: =2.7.8.5 [H]

Molecular weight: Translated: 20493; Mature: 20362

Theoretical pI: Translated: 11.88; Mature: 11.88

Prosite motif: PS00379 CDP_ALCOHOL_P_TRANSF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAPSRLGSPSTLRRSANALTVGRSVAGLPLVLLLQLGQPALAWVLLLLAGLSDAADGWL
CCCCCCCCCCHHHHHCCCHHHHCCHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCHHHHHH
ARRAGGGSSWGARLDPLADKLLLAAPMIWLASNEALPVWSIWLLLARELLISGWRAQASS
HHHCCCCCCCCCCCCHHHHHHHHHHHHHHEECCCCCHHHHHHHHHHHHHHHHCHHHCCCC
GAPASWGGKAKTILQFLSMLLLLWPPSWGSHNFCLNMQHLGWWLFWPSLILAFSSAVAYI
CCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHC
KPRSRIDRH
CCHHHCCCC
>Mature Secondary Structure 
SAPSRLGSPSTLRRSANALTVGRSVAGLPLVLLLQLGQPALAWVLLLLAGLSDAADGWL
CCCCCCCCCHHHHHCCCHHHHCCHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCHHHHHH
ARRAGGGSSWGARLDPLADKLLLAAPMIWLASNEALPVWSIWLLLARELLISGWRAQASS
HHHCCCCCCCCCCCCHHHHHHHHHHHHHHEECCCCCHHHHHHHHHHHHHHHHCHHHCCCC
GAPASWGGKAKTILQFLSMLLLLWPPSWGSHNFCLNMQHLGWWLFWPSLILAFSSAVAYI
CCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHC
KPRSRIDRH
CCHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA