BacMap

Definition	Shigella flexneri 2a str. 2457T, complete genome.
Accession	NC_004741
Length	4,599,354

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The map label for this gene is cbiO1 [H]

Identifier: 30064241

GI number: 30064241

Start: 3002644

End: 3003321

Strand: Direct

Name: cbiO1 [H]

Synonym: S3118

Alternate gene names: 30064241

Gene position: 3002644-3003321 (Clockwise)

Preceding gene: 30064240

Following gene: 30064247

Centisome position: 65.28

GC content: 52.95

Gene sequence:

>678_bases
ATGTTAACGTTAAATAAGATATCTTATCGCTGGCCTGGCGCGGCAACGGATTGTCTTTGCGACATTTCTCTGCAACTCAA
ACAAGGTGAATGGTTGGCGCTGACCGGTGACAATGGCGCAGGGAAATCGACGCTGTTACGAGTAATGGCAGGTCTTCTTA
CGCCCACAGCCGGTACGGTTATGCTGCAACAACAGGCGATGAAAAACCTGAAAAACCGCCAGCGCGCGGCAAAGGTTGGC
GTACTGTTTCAGGAAGCGGAAAACCAACTTTTTCACAGCACCGTCGCTGACGAGATCGCATTTGGTTTGAAACTGCAAAA
ATGCCCGGCGGATGAAATCACTCAACGTACCCATGCTGCCCTGCAATGTTGTCAGTTAGCAGACACTGCCAACTCGCACC
CGTTGGATCTGCATAATGCGCAGCGACGGATGGTCGCCGTCGCCTGCCTGGAAGCACTCTCTCCGCCACTATTACTGCTG
GACGAGCCGAGTCGGGATTTTGACGAAAATTGGTTGAGCGTGTTTGAAAGCTGGCTGGAGAAGTGCCGCCAGCGAGGCAC
GAGCGTGGTAGCAATCAGTCATGACGCCGCATTTACCCGGCGTCATTTCTCTCGTGTGGTGCGGCTGGAAGATGGTGTAA
TCAGGAACGTTAATCCACCAGACGATATTCACCCGTAG

Upstream 100 bases:

>100_bases
AACGTGGTTCGCTGATTATTCTTTTTGAACGTCATCGCACACCTTTCCTGAACTACTGCCAGCAAGCGTGGCAATTGCAA
AACGGAGCGCTCCAGCCACT

Downstream 100 bases:

>100_bases
CGGTCATCATTAAGGTCAAATTTGCAGGCAGACTCTCTTCCAGCCCCCGGCGAACATTCGGCCCGTCGGTACGGTCATAA
AAGGCTTCTGCATCTGCCAG

Product: putative ATP-binding protein of ABC transport system

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 225; Mature: 225

Protein sequence:

>225_residues
MLTLNKISYRWPGAATDCLCDISLQLKQGEWLALTGDNGAGKSTLLRVMAGLLTPTAGTVMLQQQAMKNLKNRQRAAKVG
VLFQEAENQLFHSTVADEIAFGLKLQKCPADEITQRTHAALQCCQLADTANSHPLDLHNAQRRMVAVACLEALSPPLLLL
DEPSRDFDENWLSVFESWLEKCRQRGTSVVAISHDAAFTRRHFSRVVRLEDGVIRNVNPPDDIHP

Sequences:

>Translated_225_residues
MLTLNKISYRWPGAATDCLCDISLQLKQGEWLALTGDNGAGKSTLLRVMAGLLTPTAGTVMLQQQAMKNLKNRQRAAKVG
VLFQEAENQLFHSTVADEIAFGLKLQKCPADEITQRTHAALQCCQLADTANSHPLDLHNAQRRMVAVACLEALSPPLLLL
DEPSRDFDENWLSVFESWLEKCRQRGTSVVAISHDAAFTRRHFSRVVRLEDGVIRNVNPPDDIHP
>Mature_225_residues
MLTLNKISYRWPGAATDCLCDISLQLKQGEWLALTGDNGAGKSTLLRVMAGLLTPTAGTVMLQQQAMKNLKNRQRAAKVG
VLFQEAENQLFHSTVADEIAFGLKLQKCPADEITQRTHAALQCCQLADTANSHPLDLHNAQRRMVAVACLEALSPPLLLL
DEPSRDFDENWLSVFESWLEKCRQRGTSVVAISHDAAFTRRHFSRVVRLEDGVIRNVNPPDDIHP

Specific function: Part of the ABC transporter complex CbiONQ involved in cobalt import. Responsible for energy coupling to the transport system [H]

COG id: COG1118

COG function: function code P; ABC-type sulfate/molybdate transport systems, ATPase component

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Homo sapiens, GI4505771, Length=232, Percent_Identity=28.448275862069, Blast_Score=89, Evalue=3e-18,
Organism=Homo sapiens, GI9961252, Length=232, Percent_Identity=28.448275862069, Blast_Score=89, Evalue=3e-18,
Organism=Homo sapiens, GI9961250, Length=239, Percent_Identity=27.6150627615063, Blast_Score=82, Evalue=4e-16,
Organism=Homo sapiens, GI42741659, Length=222, Percent_Identity=26.1261261261261, Blast_Score=78, Evalue=7e-15,
Organism=Homo sapiens, GI255708477, Length=224, Percent_Identity=25.4464285714286, Blast_Score=75, Evalue=5e-14,
Organism=Homo sapiens, GI9955963, Length=187, Percent_Identity=28.8770053475936, Blast_Score=64, Evalue=9e-11,
Organism=Escherichia coli, GI87081834, Length=214, Percent_Identity=33.1775700934579, Blast_Score=108, Evalue=4e-25,
Organism=Escherichia coli, GI1787370, Length=212, Percent_Identity=33.9622641509434, Blast_Score=107, Evalue=5e-25,
Organism=Escherichia coli, GI1788761, Length=215, Percent_Identity=35.8139534883721, Blast_Score=107, Evalue=6e-25,
Organism=Escherichia coli, GI1789873, Length=215, Percent_Identity=29.7674418604651, Blast_Score=103, Evalue=7e-24,
Organism=Escherichia coli, GI87081791, Length=206, Percent_Identity=33.9805825242718, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI1790467, Length=206, Percent_Identity=30.5825242718447, Blast_Score=100, Evalue=6e-23,
Organism=Escherichia coli, GI1789032, Length=208, Percent_Identity=29.8076923076923, Blast_Score=94, Evalue=8e-21,
Organism=Escherichia coli, GI1786398, Length=207, Percent_Identity=29.4685990338164, Blast_Score=90, Evalue=1e-19,
Organism=Escherichia coli, GI87082267, Length=225, Percent_Identity=26.2222222222222, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI1788225, Length=206, Percent_Identity=30.0970873786408, Blast_Score=89, Evalue=4e-19,
Organism=Escherichia coli, GI1787029, Length=218, Percent_Identity=27.0642201834862, Blast_Score=88, Evalue=6e-19,
Organism=Escherichia coli, GI1787089, Length=220, Percent_Identity=30.4545454545455, Blast_Score=84, Evalue=5e-18,
Organism=Escherichia coli, GI1790739, Length=210, Percent_Identity=30, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1787712, Length=205, Percent_Identity=28.2926829268293, Blast_Score=83, Evalue=1e-17,
Organism=Escherichia coli, GI87081709, Length=226, Percent_Identity=25.6637168141593, Blast_Score=82, Evalue=2e-17,
Organism=Escherichia coli, GI1786253, Length=199, Percent_Identity=32.6633165829146, Blast_Score=81, Evalue=4e-17,
Organism=Escherichia coli, GI1790525, Length=202, Percent_Identity=28.2178217821782, Blast_Score=81, Evalue=6e-17,
Organism=Escherichia coli, GI1789672, Length=230, Percent_Identity=26.0869565217391, Blast_Score=77, Evalue=7e-16,
Organism=Escherichia coli, GI48995001, Length=202, Percent_Identity=28.2178217821782, Blast_Score=77, Evalue=8e-16,
Organism=Escherichia coli, GI1786563, Length=179, Percent_Identity=32.9608938547486, Blast_Score=77, Evalue=8e-16,
Organism=Escherichia coli, GI1787164, Length=214, Percent_Identity=31.3084112149533, Blast_Score=77, Evalue=9e-16,
Organism=Escherichia coli, GI1786803, Length=212, Percent_Identity=26.8867924528302, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1786872, Length=228, Percent_Identity=27.6315789473684, Blast_Score=74, Evalue=6e-15,
Organism=Escherichia coli, GI1789891, Length=207, Percent_Identity=30.4347826086957, Blast_Score=73, Evalue=1e-14,
Organism=Escherichia coli, GI1788897, Length=209, Percent_Identity=28.7081339712919, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI1787105, Length=227, Percent_Identity=26.8722466960352, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI1788210, Length=201, Percent_Identity=30.3482587064677, Blast_Score=70, Evalue=9e-14,
Organism=Escherichia coli, GI1788506, Length=211, Percent_Identity=28.436018957346, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1788472, Length=216, Percent_Identity=23.6111111111111, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1789864, Length=241, Percent_Identity=25.7261410788382, Blast_Score=69, Evalue=2e-13,
Organism=Escherichia coli, GI1786345, Length=231, Percent_Identity=28.1385281385281, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1787792, Length=202, Percent_Identity=29.7029702970297, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1787759, Length=243, Percent_Identity=26.7489711934156, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1790190, Length=206, Percent_Identity=24.7572815533981, Blast_Score=68, Evalue=4e-13,
Organism=Escherichia coli, GI1786703, Length=201, Percent_Identity=28.3582089552239, Blast_Score=68, Evalue=6e-13,
Organism=Escherichia coli, GI1787500, Length=211, Percent_Identity=26.5402843601896, Blast_Score=67, Evalue=9e-13,
Organism=Escherichia coli, GI1786698, Length=212, Percent_Identity=26.4150943396226, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI2367384, Length=194, Percent_Identity=27.8350515463918, Blast_Score=65, Evalue=3e-12,
Organism=Escherichia coli, GI1786319, Length=194, Percent_Identity=26.8041237113402, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1787547, Length=204, Percent_Identity=22.0588235294118, Blast_Score=63, Evalue=1e-11,
Organism=Escherichia coli, GI1787143, Length=229, Percent_Identity=24.4541484716157, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1788450, Length=223, Percent_Identity=25.5605381165919, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI87082268, Length=213, Percent_Identity=23.4741784037559, Blast_Score=62, Evalue=3e-11,
Organism=Escherichia coli, GI1788644, Length=237, Percent_Identity=24.4725738396624, Blast_Score=62, Evalue=4e-11,
Organism=Escherichia coli, GI1789593, Length=182, Percent_Identity=27.4725274725275, Blast_Score=61, Evalue=7e-11,
Organism=Caenorhabditis elegans, GI25146777, Length=229, Percent_Identity=25.764192139738, Blast_Score=80, Evalue=7e-16,
Organism=Caenorhabditis elegans, GI17558664, Length=228, Percent_Identity=25.4385964912281, Blast_Score=77, Evalue=8e-15,
Organism=Caenorhabditis elegans, GI193211015, Length=234, Percent_Identity=23.5042735042735, Blast_Score=70, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI17543740, Length=235, Percent_Identity=22.9787234042553, Blast_Score=68, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI193211017, Length=234, Percent_Identity=23.5042735042735, Blast_Score=68, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI71996809, Length=234, Percent_Identity=23.5042735042735, Blast_Score=68, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI115533608, Length=161, Percent_Identity=29.1925465838509, Blast_Score=67, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI212646699, Length=210, Percent_Identity=25.2380952380952, Blast_Score=66, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17569143, Length=228, Percent_Identity=25, Blast_Score=66, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6323217, Length=197, Percent_Identity=23.3502538071066, Blast_Score=66, Evalue=4e-12,
Organism=Drosophila melanogaster, GI24666092, Length=201, Percent_Identity=24.8756218905473, Blast_Score=67, Evalue=7e-12,
Organism=Drosophila melanogaster, GI28573571, Length=176, Percent_Identity=28.4090909090909, Blast_Score=67, Evalue=9e-12,
Organism=Drosophila melanogaster, GI28573573, Length=176, Percent_Identity=28.4090909090909, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24659289, Length=184, Percent_Identity=27.1739130434783, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI281363262, Length=222, Percent_Identity=25.6756756756757, Blast_Score=64, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR015856
- InterPro:   IPR003593
- InterPro:   IPR022112 [H]

Pfam domain/function: PF00005 ABC_tran; PF12370 CoABC_C [H]

EC number: NA

Molecular weight: Translated: 24996; Mature: 24996

Theoretical pI: Translated: 7.14; Mature: 7.14

Prosite motif: PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.1 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
3.1 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLTLNKISYRWPGAATDCLCDISLQLKQGEWLALTGDNGAGKSTLLRVMAGLLTPTAGTV
CCCCCCCCEECCCCCCHHEEECEEEECCCCEEEEECCCCCCHHHHHHHHHHHHCCCCHHH
MLQQQAMKNLKNRQRAAKVGVLFQEAENQLFHSTVADEIAFGLKLQKCPADEITQRTHAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEECCCCHHHHHHHHHHH
LQCCQLADTANSHPLDLHNAQRRMVAVACLEALSPPLLLLDEPSRDFDENWLSVFESWLE
HHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHH
KCRQRGTSVVAISHDAAFTRRHFSRVVRLEDGVIRNVNPPDDIHP
HHHHCCCEEEEEECCHHHHHHHHHHHHHHCCCEECCCCCCCCCCC
>Mature Secondary Structure
MLTLNKISYRWPGAATDCLCDISLQLKQGEWLALTGDNGAGKSTLLRVMAGLLTPTAGTV
CCCCCCCCEECCCCCCHHEEECEEEECCCCEEEEECCCCCCHHHHHHHHHHHHCCCCHHH
MLQQQAMKNLKNRQRAAKVGVLFQEAENQLFHSTVADEIAFGLKLQKCPADEITQRTHAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEECCCCHHHHHHHHHHH
LQCCQLADTANSHPLDLHNAQRRMVAVACLEALSPPLLLLDEPSRDFDENWLSVFESWLE
HHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHH
KCRQRGTSVVAISHDAAFTRRHFSRVVRLEDGVIRNVNPPDDIHP
HHHHCCCEEEEEECCHHHHHHHHHHHHHHCCCEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12663927 [H]