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The map label for this gene is cysA [C]

Identifier: 30064240

GI number: 30064240

Start: 3001973

End: 3002650

Strand: Direct

Name: cysA [C]

Synonym: S3117

Alternate gene names: 30064240

Gene position: 3001973-3002650 (Clockwise)

Preceding gene: 30064239

Following gene: 30064241

Centisome position: 65.27

GC content: 54.28

Gene sequence:

>678_bases
ATGGTTACGTTAGAACAGTTCCGTTATTGCCCGACACACTCAACGCATCCTCCGTTCTGTTATGACTTTCACTATGTCAA
ACCGGGGATGGTCGCCATCTTTGGTGACAACGGCAGTGGCAAAAGTACGCTGGCACAGCTGATGGCGGGCTGGTATCCGG
ACTTTCTGCCAAGAGAGATAACAGGCACGGGGACGCTCCTCGGTACGCCCATTGGGCATCTCCCGCTTAATGAACAATCC
GCCACCATCCAGCTCGTCCAGCAATCGCCCTATTTGCAGCTCTCCGGCTGTACCTTTAGCGTGGAAGAAGAAGTTGCCTT
TGGGCCAGAAAATCTGTGTCTTGCTGAAGCAGAGATTATGGCGCGGATTGATGCCGCCCTGACTCTGACCGAGTGCCAGC
CGTTGCGCCATCGTCACCCGGCAACACTCTCCGGTGGAGAGACACAGCGCGTGATCATCGCCTGCGCCATCGCGATGCAG
CCAAAGCTCTTAATTCTTGATGAAGCCTTTAGCCGCCTGACACCGCAGGCCAGCGAAATGCTGTTGCAGCGCTTACAACA
CTGGGCGTTTGAACGTGGTTCGCTGATTATTCTTTTTGAACGTCATCGCACACCTTTCCTGAACTACTGCCAGCAAGCGT
GGCAATTGCAAAACGGAGCGCTCCAGCCACTATGTTAA

Upstream 100 bases:

>100_bases
ACCGACGAACAACGTTGTGGGCACCAGCCGATAGCACCCTACAACGCGTAGCGCGTTACACCATGATCTTGCTGATGCTG
ACAGAATTCGGAGCGTGGAT

Downstream 100 bases:

>100_bases
CGTTAAATAAGATATCTTATCGCTGGCCTGGCGCGGCAACGGATTGTCTTTGCGACATTTCTCTGCAACTCAAACAAGGT
GAATGGTTGGCGCTGACCGG

Product: putative ATP-binding protein of ABC transport system

Products: ADP; phosphate; S2O32- [Cytoplasm]; SO42- [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 225; Mature: 225

Protein sequence:

>225_residues
MVTLEQFRYCPTHSTHPPFCYDFHYVKPGMVAIFGDNGSGKSTLAQLMAGWYPDFLPREITGTGTLLGTPIGHLPLNEQS
ATIQLVQQSPYLQLSGCTFSVEEEVAFGPENLCLAEAEIMARIDAALTLTECQPLRHRHPATLSGGETQRVIIACAIAMQ
PKLLILDEAFSRLTPQASEMLLQRLQHWAFERGSLIILFERHRTPFLNYCQQAWQLQNGALQPLC

Sequences:

>Translated_225_residues
MVTLEQFRYCPTHSTHPPFCYDFHYVKPGMVAIFGDNGSGKSTLAQLMAGWYPDFLPREITGTGTLLGTPIGHLPLNEQS
ATIQLVQQSPYLQLSGCTFSVEEEVAFGPENLCLAEAEIMARIDAALTLTECQPLRHRHPATLSGGETQRVIIACAIAMQ
PKLLILDEAFSRLTPQASEMLLQRLQHWAFERGSLIILFERHRTPFLNYCQQAWQLQNGALQPLC
>Mature_225_residues
MVTLEQFRYCPTHSTHPPFCYDFHYVKPGMVAIFGDNGSGKSTLAQLMAGWYPDFLPREITGTGTLLGTPIGHLPLNEQS
ATIQLVQQSPYLQLSGCTFSVEEEVAFGPENLCLAEAEIMARIDAALTLTECQPLRHRHPATLSGGETQRVIIACAIAMQ
PKLLILDEAFSRLTPQASEMLLQRLQHWAFERGSLIILFERHRTPFLNYCQQAWQLQNGALQPLC

Specific function: Probably part of an ABC transporter complex. Responsible for energy coupling to the transport system [H]

COG id: COG1122

COG function: function code P; ABC-type cobalt transport system, ATPase component

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Homo sapiens, GI4505771, Length=187, Percent_Identity=32.0855614973262, Blast_Score=70, Evalue=1e-12,
Organism=Homo sapiens, GI9961252, Length=187, Percent_Identity=32.0855614973262, Blast_Score=70, Evalue=1e-12,
Organism=Homo sapiens, GI9961250, Length=189, Percent_Identity=31.2169312169312, Blast_Score=66, Evalue=2e-11,
Organism=Homo sapiens, GI73747915, Length=212, Percent_Identity=34.9056603773585, Blast_Score=65, Evalue=4e-11,
Organism=Homo sapiens, GI42741659, Length=187, Percent_Identity=31.0160427807487, Blast_Score=65, Evalue=5e-11,
Organism=Escherichia coli, GI1788761, Length=161, Percent_Identity=31.6770186335404, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI87081791, Length=164, Percent_Identity=31.0975609756098, Blast_Score=71, Evalue=8e-14,
Organism=Escherichia coli, GI1787029, Length=203, Percent_Identity=31.5270935960591, Blast_Score=70, Evalue=8e-14,
Organism=Escherichia coli, GI1786653, Length=224, Percent_Identity=29.4642857142857, Blast_Score=68, Evalue=5e-13,
Organism=Escherichia coli, GI1787370, Length=212, Percent_Identity=27.3584905660377, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI87081709, Length=161, Percent_Identity=29.1925465838509, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1789891, Length=197, Percent_Identity=29.4416243654822, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI1787792, Length=186, Percent_Identity=31.7204301075269, Blast_Score=62, Evalue=3e-11,
Organism=Escherichia coli, GI1786398, Length=193, Percent_Identity=28.4974093264249, Blast_Score=61, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI17543740, Length=204, Percent_Identity=31.3725490196078, Blast_Score=76, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17565938, Length=181, Percent_Identity=33.1491712707182, Blast_Score=71, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI17541710, Length=172, Percent_Identity=31.3953488372093, Blast_Score=67, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI115534520, Length=201, Percent_Identity=28.8557213930348, Blast_Score=65, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI71984940, Length=196, Percent_Identity=28.5714285714286, Blast_Score=65, Evalue=4e-11,
Organism=Drosophila melanogaster, GI24653245, Length=180, Percent_Identity=31.6666666666667, Blast_Score=70, Evalue=9e-13,
Organism=Drosophila melanogaster, GI281363262, Length=180, Percent_Identity=31.6666666666667, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI17136662, Length=223, Percent_Identity=30.4932735426009, Blast_Score=69, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR003593 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: 3.6.3.25 [C]

Molecular weight: Translated: 25158; Mature: 25158

Theoretical pI: Translated: 6.07; Mature: 6.07

Prosite motif: PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.6 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
3.6 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVTLEQFRYCPTHSTHPPFCYDFHYVKPGMVAIFGDNGSGKSTLAQLMAGWYPDFLPREI
CCCHHHCCCCCCCCCCCCEEEEEEEECCCEEEEECCCCCCHHHHHHHHHHCCCCCCCCCC
TGTGTLLGTPIGHLPLNEQSATIQLVQQSPYLQLSGCTFSVEEEVAFGPENLCLAEAEIM
CCCCEEECCCCCCCCCCCCCCEEEEEECCCCEEEECCEEEECHHHCCCCCCHHHHHHHHH
ARIDAALTLTECQPLRHRHPATLSGGETQRVIIACAIAMQPKLLILDEAFSRLTPQASEM
HHHHHHEEEECCCHHHHCCCCCCCCCCCCEEEEEEEECCCCCEEEHHHHHHHCCCHHHHH
LLQRLQHWAFERGSLIILFERHRTPFLNYCQQAWQLQNGALQPLC
HHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MVTLEQFRYCPTHSTHPPFCYDFHYVKPGMVAIFGDNGSGKSTLAQLMAGWYPDFLPREI
CCCHHHCCCCCCCCCCCCEEEEEEEECCCEEEEECCCCCCHHHHHHHHHHCCCCCCCCCC
TGTGTLLGTPIGHLPLNEQSATIQLVQQSPYLQLSGCTFSVEEEVAFGPENLCLAEAEIM
CCCCEEECCCCCCCCCCCCCCEEEEEECCCCEEEECCEEEECHHHCCCCCCHHHHHHHHH
ARIDAALTLTECQPLRHRHPATLSGGETQRVIIACAIAMQPKLLILDEAFSRLTPQASEM
HHHHHHEEEECCCHHHHCCCCCCCCCCCCEEEEEEEECCCCCEEEHHHHHHHCCCHHHHH
LLQRLQHWAFERGSLIILFERHRTPFLNYCQQAWQLQNGALQPLC
HHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: S2O32- [Periplasm]; H2O; SO42- [Periplasm]; ATP [C]

Specific reaction: ATP + S2O32- [Periplasm] + H2O = ADP + phosphate + S2O32- [Cytoplasm] SO42- [Periplasm] + H2O + ATP = SO42- [Cytoplasm] + phosphate + ADP [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12125824 [H]