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The map label for this gene is hflC [H]

Identifier: 30064247

GI number: 30064247

Start: 3007927

End: 3008835

Strand: Direct

Name: hflC [H]

Synonym: S3126

Alternate gene names: 30064247

Gene position: 3007927-3008835 (Clockwise)

Preceding gene: 30064241

Following gene: 30064249

Centisome position: 65.4

GC content: 48.84

Gene sequence:

>909_bases
ATGAAAGCACCTGTTTCATTAACCTCATTTCGCCCACAAAAATCTCTTGCTATCGCCATTGGCGTGCTTGCCGTGGTTGT
GCTGCCATTTCTCTCGTATTACACCGTTAATGAAGGTGAACGCGGCATTTTGCTGCGCTACGGAAAAATCGTAAAAGTTG
CCGAACCGGGGCTGGGTTTTAAGATCCCTTTTATGGAAAGCGTGGAGAAAATTTCCACGCGTAATCAGGCTGTGGTCTAT
CAGGGATTACAGGCCTACAGCCGCGACCAGCAACCGGCACAAATGACAGTATCAGTCAGCTTCCACATTAAACCTTCAGA
AGCAGGCGCGGTTTATACCACCTACAACACTATTGAAGCATTAAAAGATCGTCTAATTGTCCGTCAGTTGCCAACTCAGC
TGGAGAACATTTTCGGCCAATATACCGCCATCAGCGCCGTACAGGATCGTACAAAATTGGTTCAGGATCTGCAAAATGCC
ATGCGCAAAGCCGTTGTTGGGCCAGTGGTAATTGACGGGGTCCAGATTGAAAATATTGATTTTTCTGACGCTTATGAAAA
GTCGATTGAAAACCGAATGAAAGCAGAAGTCGCCATTGCCACGCGTAAGCAAAATCTGGAAACAGAGAAAATCCAGGCGC
AAATAGCGGTAACTCAGGCCCAGGCAGAAGCAGACAGTAAACTGGCGGCAGCCAAAGCAGAAGCGGAAACTATTCGCGTA
AGAGGCGCGGCAGAGGCTGAAACTATTCGTTTAAAAAGTGCGGCTGAAGCAGAAGCAATCCGCCTGCGCGGTGAAGCTCT
GCGGGATAATCCCGGACTTGTAGCCCTCACCACTGCCGAACGTTGGGACGGTAAACTGCCCGATACCATGATCCCCGGCA
GCACAGTTCCGTTTATCTCTACTAAGTAA

Upstream 100 bases:

>100_bases
TTTCGCTATACCCCTTTATAGATTCTGAATTCTCACCTGTCGGCTGTTTTCTCCTCATCTCATGTGACATATTCCCATAC
TTTACTCAAGGAAGATTGTC

Downstream 100 bases:

>100_bases
AAAAAGGGCCGCTTTCGCGGTCCTTCTCACAAAACGTCTTACTGATTACAGCAGCGCTTTTGCTTTCGCAACAACGTTAT
CAACAGTGAAGCCGAACTCT

Product: putative serine protease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 302; Mature: 302

Protein sequence:

>302_residues
MKAPVSLTSFRPQKSLAIAIGVLAVVVLPFLSYYTVNEGERGILLRYGKIVKVAEPGLGFKIPFMESVEKISTRNQAVVY
QGLQAYSRDQQPAQMTVSVSFHIKPSEAGAVYTTYNTIEALKDRLIVRQLPTQLENIFGQYTAISAVQDRTKLVQDLQNA
MRKAVVGPVVIDGVQIENIDFSDAYEKSIENRMKAEVAIATRKQNLETEKIQAQIAVTQAQAEADSKLAAAKAEAETIRV
RGAAEAETIRLKSAAEAEAIRLRGEALRDNPGLVALTTAERWDGKLPDTMIPGSTVPFISTK

Sequences:

>Translated_302_residues
MKAPVSLTSFRPQKSLAIAIGVLAVVVLPFLSYYTVNEGERGILLRYGKIVKVAEPGLGFKIPFMESVEKISTRNQAVVY
QGLQAYSRDQQPAQMTVSVSFHIKPSEAGAVYTTYNTIEALKDRLIVRQLPTQLENIFGQYTAISAVQDRTKLVQDLQNA
MRKAVVGPVVIDGVQIENIDFSDAYEKSIENRMKAEVAIATRKQNLETEKIQAQIAVTQAQAEADSKLAAAKAEAETIRV
RGAAEAETIRLKSAAEAEAIRLRGEALRDNPGLVALTTAERWDGKLPDTMIPGSTVPFISTK
>Mature_302_residues
MKAPVSLTSFRPQKSLAIAIGVLAVVVLPFLSYYTVNEGERGILLRYGKIVKVAEPGLGFKIPFMESVEKISTRNQAVVY
QGLQAYSRDQQPAQMTVSVSFHIKPSEAGAVYTTYNTIEALKDRLIVRQLPTQLENIFGQYTAISAVQDRTKLVQDLQNA
MRKAVVGPVVIDGVQIENIDFSDAYEKSIENRMKAEVAIATRKQNLETEKIQAQIAVTQAQAEADSKLAAAKAEAETIRV
RGAAEAETIRLKSAAEAEAIRLRGEALRDNPGLVALTTAERWDGKLPDTMIPGSTVPFISTK

Specific function: HflC and HflK could encode or regulate a protease [H]

COG id: COG0330

COG function: function code O; Membrane protease subunits, stomatin/prohibitin homologs

Gene ontology:

Cell location: Membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the band 7/mec-2 family. HflC subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790617, Length=301, Percent_Identity=24.5847176079734, Blast_Score=67, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001107
- InterPro:   IPR010200
- InterPro:   IPR001972 [H]

Pfam domain/function: PF01145 Band_7 [H]

EC number: 3.4.-.- [C]

Molecular weight: Translated: 33050; Mature: 33050

Theoretical pI: Translated: 9.38; Mature: 9.38

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKAPVSLTSFRPQKSLAIAIGVLAVVVLPFLSYYTVNEGERGILLRYGKIVKVAEPGLGF
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHEEECCCCCEEEEEECCEEEEECCCCCE
KIPFMESVEKISTRNQAVVYQGLQAYSRDQQPAQMTVSVSFHIKPSEAGAVYTTYNTIEA
ECCHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCEEEEEEEEEECCCCCCEEEEEHHHHHH
LKDRLIVRQLPTQLENIFGQYTAISAVQDRTKLVQDLQNAMRKAVVGPVVIDGVQIENID
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCEEEECCC
FSDAYEKSIENRMKAEVAIATRKQNLETEKIQAQIAVTQAQAEADSKLAAAKAEAETIRV
CHHHHHHHHHHHHHHHHEEEHHHCCCCHHHHHEEHEEHHHHHHHHHHHHHHHCCCCEEEE
RGAAEAETIRLKSAAEAEAIRLRGEALRDNPGLVALTTAERWDGKLPDTMIPGSTVPFIS
ECCCCCCEEEECCCCHHHHHHHCCHHHCCCCCEEEEEECHHCCCCCCCCCCCCCCCCCEE
TK
CC
>Mature Secondary Structure
MKAPVSLTSFRPQKSLAIAIGVLAVVVLPFLSYYTVNEGERGILLRYGKIVKVAEPGLGF
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHEEECCCCCEEEEEECCEEEEECCCCCE
KIPFMESVEKISTRNQAVVYQGLQAYSRDQQPAQMTVSVSFHIKPSEAGAVYTTYNTIEA
ECCHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCEEEEEEEEEECCCCCCEEEEEHHHHHH
LKDRLIVRQLPTQLENIFGQYTAISAVQDRTKLVQDLQNAMRKAVVGPVVIDGVQIENID
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCEEEECCC
FSDAYEKSIENRMKAEVAIATRKQNLETEKIQAQIAVTQAQAEADSKLAAAKAEAETIRV
CHHHHHHHHHHHHHHHHEEEHHHCCCCHHHHHEEHEEHHHHHHHHHHHHHHHCCCCEEEE
RGAAEAETIRLKSAAEAEAIRLRGEALRDNPGLVALTTAERWDGKLPDTMIPGSTVPFIS
ECCCCCCEEEECCCCHHHHHHHCCHHHCCCCCEEEEEECHHCCCCCCCCCCCCCCCCCEE
TK
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases) [C]

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12089438 [H]