Click here to switch to the map view.

The map label for this gene is exuT [H]

Identifier: 29349513

GI number: 29349513

Start: 5367284

End: 5368771

Strand: Reverse

Name: exuT [H]

Synonym: BT_4105

Alternate gene names: 29349513

Gene position: 5368771-5367284 (Counterclockwise)

Preceding gene: 29349514

Following gene: 29349507

Centisome position: 85.76

GC content: 47.38

Gene sequence:

>1488_bases
ATGACAAACTACAGATGGACGATCTGTGCGATGCTATTTTTTGCTACTACAGTTAACTATCTCGACCGCCAGGTACTATC
GCTCACCTGGGATGAATTTATCAAACCGGAATTTCACTGGGATGAATCACACTACGGTACTATCACTTCCGTATTCTCTA
TTGTTTACGCAATATGTATGCTCTTTGCCGGTCGCTTTGTGGACTGGATGGGAACGAAGAAAGGATTCCTCTGGGCTATC
GGCGTATGGTCTGCCGGTGCCTGTCTGCACGCAGTCTGTGGTATTGTAACAGAAGCGCAGGTAGGACTGCACAGTGCTGC
CGAACTTGCCGGAGCCACCGGAGACGTGGTGGTAACCATCGCTACTGTCAGTATGTACTGCTTCCTGGCTGCACGCTGTA
TACTTGCTCTCGGAGAAGCCGGTAACTTCCCCGCCGCTATTAAAGTAACTGCCGAGTACTTCCCGAAGAAAGACCGTGCT
TATGCTACTTCCATCTTCAACGCCGGTGCTTCTATCGGTGCCTTGATCGCTCCGCTCACCATTCCTATCCTTGCCAAAGC
TTTCGGTTGGGAAATGGCGTTTATCGTTATTGGTGGACTTGGTTTTATCTGGATGGGCTTCTGGGTATTTATGTATGATG
CTCCTTCAAAGAGCAAGCACGTAAACAAAGCCGAACTTGAATATATCGAACAAGACCAGAATGAGGCCGGTGCAGGTCCG
AAAACAGAGGAGAAAGACGAGAAAAAGATGAGATTCTGGCAATGTTTCAGCTACAAACAAACTTGGGCATTTGTCTTCGG
TAAATTTACCACTGACGGTGTATGGTGGTTCTTCCTGTTCTGGACCCCGTCTTACCTGAACTCCCAATTCGGTATCAAAA
CTTCCGATCCTCTGGGAATGGGACTTATCTTCACACTTTACGCAATCACGATGTTATCCATCTACGGTGGCAAGCTTCCT
ACTATCTTCATCAACAAGACCGGCATGAACCCTTATGCGGCACGTATGAAAGCAATGTTGATTTTCGCATTCTTCCCGTT
AGTGGTATTGCTGGCACAGCCATTGGGAACATTCTCTCCGTGGTTCCCCGTGATCCTGATCGGTATCGGCGGAGCTGCCC
ACCAGTCATGGTCGGCTAATATCTTCTCTACAGTAGGTGATATGTTCCCCCGAACAGCAATTGCAAGTATCACCGGTATC
GGTGGTATGGCCGGTGGTATCGGTTCAATGATTCTTCAGAAAGTGGCAGGTAACTTATTTGTATATGCTTCCGGAACAAC
AATGGTTGACGGCAAAGAAGTGGAAATGACAAAAGAACTACTGGAACAAGGAGCACAGTTTGTACATCCTGCGATGACAT
TCATGGGCTTCGAAGGAAAACCGGCCGGTTACTTTGTAATCTTCTGTGTATGCGCAGTGGCTTACCTGATCGGTTGGGTT
ATTATGAAAGCACTGGTTCCTAAATATAAGCCTATCGTATTGGATTAA

Upstream 100 bases:

>100_bases
TATTACAAAAAAAATCCAGCTGAAATACCGACCTTTGTCAGCAAATCAAAATCTATTTAAATCCATTATCATGAATGCAT
TTCAAAAAACAGGCGAAAAA

Downstream 100 bases:

>100_bases
TCCGATATAATTATATAGAATAAAAAACAGGAGGGCACTCAGCATGAGTTTGTCCTCCTGTTTTTTTAACCAATTATTTA
TTCAAAAAGTTCCAAAAACA

Product: hexuronate transporter

Products: galacturonate [Cytoplasm]; Proton [Cytoplasm]; glucuronate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 495; Mature: 494

Protein sequence:

>495_residues
MTNYRWTICAMLFFATTVNYLDRQVLSLTWDEFIKPEFHWDESHYGTITSVFSIVYAICMLFAGRFVDWMGTKKGFLWAI
GVWSAGACLHAVCGIVTEAQVGLHSAAELAGATGDVVVTIATVSMYCFLAARCILALGEAGNFPAAIKVTAEYFPKKDRA
YATSIFNAGASIGALIAPLTIPILAKAFGWEMAFIVIGGLGFIWMGFWVFMYDAPSKSKHVNKAELEYIEQDQNEAGAGP
KTEEKDEKKMRFWQCFSYKQTWAFVFGKFTTDGVWWFFLFWTPSYLNSQFGIKTSDPLGMGLIFTLYAITMLSIYGGKLP
TIFINKTGMNPYAARMKAMLIFAFFPLVVLLAQPLGTFSPWFPVILIGIGGAAHQSWSANIFSTVGDMFPRTAIASITGI
GGMAGGIGSMILQKVAGNLFVYASGTTMVDGKEVEMTKELLEQGAQFVHPAMTFMGFEGKPAGYFVIFCVCAVAYLIGWV
IMKALVPKYKPIVLD

Sequences:

>Translated_495_residues
MTNYRWTICAMLFFATTVNYLDRQVLSLTWDEFIKPEFHWDESHYGTITSVFSIVYAICMLFAGRFVDWMGTKKGFLWAI
GVWSAGACLHAVCGIVTEAQVGLHSAAELAGATGDVVVTIATVSMYCFLAARCILALGEAGNFPAAIKVTAEYFPKKDRA
YATSIFNAGASIGALIAPLTIPILAKAFGWEMAFIVIGGLGFIWMGFWVFMYDAPSKSKHVNKAELEYIEQDQNEAGAGP
KTEEKDEKKMRFWQCFSYKQTWAFVFGKFTTDGVWWFFLFWTPSYLNSQFGIKTSDPLGMGLIFTLYAITMLSIYGGKLP
TIFINKTGMNPYAARMKAMLIFAFFPLVVLLAQPLGTFSPWFPVILIGIGGAAHQSWSANIFSTVGDMFPRTAIASITGI
GGMAGGIGSMILQKVAGNLFVYASGTTMVDGKEVEMTKELLEQGAQFVHPAMTFMGFEGKPAGYFVIFCVCAVAYLIGWV
IMKALVPKYKPIVLD
>Mature_494_residues
TNYRWTICAMLFFATTVNYLDRQVLSLTWDEFIKPEFHWDESHYGTITSVFSIVYAICMLFAGRFVDWMGTKKGFLWAIG
VWSAGACLHAVCGIVTEAQVGLHSAAELAGATGDVVVTIATVSMYCFLAARCILALGEAGNFPAAIKVTAEYFPKKDRAY
ATSIFNAGASIGALIAPLTIPILAKAFGWEMAFIVIGGLGFIWMGFWVFMYDAPSKSKHVNKAELEYIEQDQNEAGAGPK
TEEKDEKKMRFWQCFSYKQTWAFVFGKFTTDGVWWFFLFWTPSYLNSQFGIKTSDPLGMGLIFTLYAITMLSIYGGKLPT
IFINKTGMNPYAARMKAMLIFAFFPLVVLLAQPLGTFSPWFPVILIGIGGAAHQSWSANIFSTVGDMFPRTAIASITGIG
GMAGGIGSMILQKVAGNLFVYASGTTMVDGKEVEMTKELLEQGAQFVHPAMTFMGFEGKPAGYFVIFCVCAVAYLIGWVI
MKALVPKYKPIVLD

Specific function: Aldohexuronate transport system [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Phthalate permease family [H]

Homologues:

Organism=Homo sapiens, GI9966811, Length=314, Percent_Identity=23.8853503184713, Blast_Score=74, Evalue=5e-13,
Organism=Homo sapiens, GI9945322, Length=316, Percent_Identity=23.1012658227848, Blast_Score=67, Evalue=3e-11,
Organism=Escherichia coli, GI2367193, Length=423, Percent_Identity=28.3687943262411, Blast_Score=154, Evalue=1e-38,
Organism=Escherichia coli, GI87082320, Length=291, Percent_Identity=27.1477663230241, Blast_Score=116, Evalue=3e-27,
Organism=Escherichia coli, GI1789515, Length=339, Percent_Identity=27.4336283185841, Blast_Score=110, Evalue=3e-25,
Organism=Escherichia coli, GI1789152, Length=300, Percent_Identity=28, Blast_Score=109, Evalue=4e-25,
Organism=Escherichia coli, GI2367379, Length=360, Percent_Identity=25.5555555555556, Blast_Score=101, Evalue=9e-23,
Organism=Drosophila melanogaster, GI24583789, Length=381, Percent_Identity=23.8845144356955, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24580790, Length=319, Percent_Identity=22.5705329153605, Blast_Score=73, Evalue=4e-13,
Organism=Drosophila melanogaster, GI24641682, Length=199, Percent_Identity=26.6331658291457, Blast_Score=67, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24655271, Length=426, Percent_Identity=21.830985915493, Blast_Score=65, Evalue=8e-11,
Organism=Drosophila melanogaster, GI20130135, Length=426, Percent_Identity=21.830985915493, Blast_Score=65, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004744
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 54526; Mature: 54395

Theoretical pI: Translated: 7.70; Mature: 7.70

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
6.3 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
6.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNYRWTICAMLFFATTVNYLDRQVLSLTWDEFIKPEFHWDESHYGTITSVFSIVYAICM
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHH
LFAGRFVDWMGTKKGFLWAIGVWSAGACLHAVCGIVTEAQVGLHSAAELAGATGDVVVTI
HHHHHHHHHHCCCCCCEEEEEHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEHH
ATVSMYCFLAARCILALGEAGNFPAAIKVTAEYFPKKDRAYATSIFNAGASIGALIAPLT
HHHHHHHHHHHHHHHHHCCCCCCCEEEEEEHHHCCCCCHHHHHHHHHCCCHHHHHHHHHH
IPILAKAFGWEMAFIVIGGLGFIWMGFWVFMYDAPSKSKHVNKAELEYIEQDQNEAGAGP
HHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCCCCCCC
KTEEKDEKKMRFWQCFSYKQTWAFVFGKFTTDGVWWFFLFWTPSYLNSQFGIKTSDPLGM
CCCCHHHHHHHHHHHHHHHHHHHHHEECCCCCCEEEEEEEECHHHHCCCCCCCCCCCCCH
GLIFTLYAITMLSIYGGKLPTIFINKTGMNPYAARMKAMLIFAFFPLVVLLAQPLGTFSP
HHHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
WFPVILIGIGGAAHQSWSANIFSTVGDMFPRTAIASITGIGGMAGGIGSMILQKVAGNLF
HHHEEEEECCCCCCCCCCCHHHHHHHHHCCHHHHHHHHCCCCHHHHHHHHHHHHHCCCEE
VYASGTTMVDGKEVEMTKELLEQGAQFVHPAMTFMGFEGKPAGYFVIFCVCAVAYLIGWV
EEECCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHH
IMKALVPKYKPIVLD
HHHHHCCCCCCEECC
>Mature Secondary Structure 
TNYRWTICAMLFFATTVNYLDRQVLSLTWDEFIKPEFHWDESHYGTITSVFSIVYAICM
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHH
LFAGRFVDWMGTKKGFLWAIGVWSAGACLHAVCGIVTEAQVGLHSAAELAGATGDVVVTI
HHHHHHHHHHCCCCCCEEEEEHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEHH
ATVSMYCFLAARCILALGEAGNFPAAIKVTAEYFPKKDRAYATSIFNAGASIGALIAPLT
HHHHHHHHHHHHHHHHHCCCCCCCEEEEEEHHHCCCCCHHHHHHHHHCCCHHHHHHHHHH
IPILAKAFGWEMAFIVIGGLGFIWMGFWVFMYDAPSKSKHVNKAELEYIEQDQNEAGAGP
HHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCCCCCCC
KTEEKDEKKMRFWQCFSYKQTWAFVFGKFTTDGVWWFFLFWTPSYLNSQFGIKTSDPLGM
CCCCHHHHHHHHHHHHHHHHHHHHHEECCCCCCEEEEEEEECHHHHCCCCCCCCCCCCCH
GLIFTLYAITMLSIYGGKLPTIFINKTGMNPYAARMKAMLIFAFFPLVVLLAQPLGTFSP
HHHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
WFPVILIGIGGAAHQSWSANIFSTVGDMFPRTAIASITGIGGMAGGIGSMILQKVAGNLF
HHHEEEEECCCCCCCCCCCHHHHHHHHHCCHHHHHHHHCCCCHHHHHHHHHHHHHCCCEE
VYASGTTMVDGKEVEMTKELLEQGAQFVHPAMTFMGFEGKPAGYFVIFCVCAVAYLIGWV
EEECCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHH
IMKALVPKYKPIVLD
HHHHHCCCCCCEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: galacturonate [Periplasm]; Proton [Periplasm]; glucuronate [Periplasm] [C]

Specific reaction: Proton [Periplasm] + galacturonate [Periplasm] = galacturonate [Cytoplasm] + Proton [Cytoplasm] Proton [Periplasm] + glucuronate [Periplasm] = Proton [Cytoplasm] + glucuronate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]