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The map label for this gene is pabA [H]

Identifier: 29144303

GI number: 29144303

Start: 4193927

End: 4194490

Strand: Direct

Name: pabA [H]

Synonym: t4036

Alternate gene names: 29144303

Gene position: 4193927-4194490 (Clockwise)

Preceding gene: 29144302

Following gene: 29144304

Centisome position: 87.52

GC content: 55.5

Gene sequence:

>564_bases
ATGATCCTGCTTATCGATAACTATGATTCCTTTACCTGGAACCTCTACCAGTATTTTTGTGAACTGGGCGCGGAAGTGCA
GGTTCGGCGCAATGATGCGCTGACGCTGGCGCACATTGACGCTTTGAACCCGCAAAAAATCGTTATCTCTCCTGGCCCCT
GTACGCCAAATGACGCTGGCATTTCACTGGCGGTCATCCGCCATTATGCCGGACGTATTCCGATGCTGGGCGTTTGCCTG
GGTCATCAGGCGATGGCGCAGGCCTTTGGCGCGTCGGTGGTGCGGGCAGCGAAAGTGATGCACGGTAAAACGTCACCTGT
TACGCATAATGGACAGGGCGTGTTTCGGGGATTGCCCAGCCCGTTAACCGTGACACGTTACCACTCGCTGATTGTCGACC
CTGCCACGTTGCCTGAGTGTTTTGAGATCACCGCCTGGAGCGAAACGCAGGAGATTATGGGCATTCGCCACCGCGAGTGG
GATCTGGAAGGCGTGCAGTTCCACCCGGAAAGTATTCTCAGCGAACAAGGACACGCTCTGCTGGAAAATTTCCTCCGGCG
TTGA

Upstream 100 bases:

>100_bases
ATGGGCGATCTCTCCGCTTTGCGGGCGATTTTTCAGAAAGCGATAAGCGAAGCTCGCGAAACTGAGTAAAATAGGGCGGT
TCTACTGACCCGGAGCCGCC

Downstream 100 bases:

>100_bases
TTTGTGGTTGCTATTGAGTGATTTTTTATTCATATTTTGTGATTATAATTTCACTGGCATTTCTACTTAACCGGGTGGTA
ATGATATGGCAACTGAACAA

Product: para-aminobenzoate synthase component II

Products: NA

Alternate protein names: ADC synthase [H]

Number of amino acids: Translated: 187; Mature: 187

Protein sequence:

>187_residues
MILLIDNYDSFTWNLYQYFCELGAEVQVRRNDALTLAHIDALNPQKIVISPGPCTPNDAGISLAVIRHYAGRIPMLGVCL
GHQAMAQAFGASVVRAAKVMHGKTSPVTHNGQGVFRGLPSPLTVTRYHSLIVDPATLPECFEITAWSETQEIMGIRHREW
DLEGVQFHPESILSEQGHALLENFLRR

Sequences:

>Translated_187_residues
MILLIDNYDSFTWNLYQYFCELGAEVQVRRNDALTLAHIDALNPQKIVISPGPCTPNDAGISLAVIRHYAGRIPMLGVCL
GHQAMAQAFGASVVRAAKVMHGKTSPVTHNGQGVFRGLPSPLTVTRYHSLIVDPATLPECFEITAWSETQEIMGIRHREW
DLEGVQFHPESILSEQGHALLENFLRR
>Mature_187_residues
MILLIDNYDSFTWNLYQYFCELGAEVQVRRNDALTLAHIDALNPQKIVISPGPCTPNDAGISLAVIRHYAGRIPMLGVCL
GHQAMAQAFGASVVRAAKVMHGKTSPVTHNGQGVFRGLPSPLTVTRYHSLIVDPATLPECFEITAWSETQEIMGIRHREW
DLEGVQFHPESILSEQGHALLENFLRR

Specific function: Catalyzes the biosynthesis of 4-amino-4-deoxychorismate (ADC) from chorismate and glutamine [H]

COG id: COG0512

COG function: function code EH; Anthranilate/para-aminobenzoate synthases component II

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutamine amidotransferase type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1789760, Length=187, Percent_Identity=85.0267379679144, Blast_Score=345, Evalue=2e-96,
Organism=Escherichia coli, GI1787517, Length=188, Percent_Identity=41.4893617021277, Blast_Score=140, Evalue=5e-35,
Organism=Escherichia coli, GI1788854, Length=191, Percent_Identity=29.3193717277487, Blast_Score=68, Evalue=3e-13,
Organism=Saccharomyces cerevisiae, GI6322638, Length=185, Percent_Identity=51.8918918918919, Blast_Score=224, Evalue=6e-60,
Organism=Saccharomyces cerevisiae, GI6324361, Length=212, Percent_Identity=29.2452830188679, Blast_Score=80, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006220
- InterPro:   IPR001317
- InterPro:   IPR011702
- InterPro:   IPR017926
- InterPro:   IPR000991
- InterPro:   IPR006221 [H]

Pfam domain/function: PF00117 GATase [H]

EC number: =2.6.1.85 [H]

Molecular weight: Translated: 20802; Mature: 20802

Theoretical pI: Translated: 6.59; Mature: 6.59

Prosite motif: PS00442 GATASE_TYPE_I ; PS00678 WD_REPEATS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MILLIDNYDSFTWNLYQYFCELGAEVQVRRNDALTLAHIDALNPQKIVISPGPCTPNDAG
CEEEEECCCCCHHHHHHHHHHCCCEEEEECCCCEEEEEECCCCCCEEEEECCCCCCCCCC
ISLAVIRHYAGRIPMLGVCLGHQAMAQAFGASVVRAAKVMHGKTSPVTHNGQGVFRGLPS
CHHHHHHHHHCCCCEEHHHHCHHHHHHHHHHHHHHHHHHHCCCCCCCEECCCCCCCCCCC
PLTVTRYHSLIVDPATLPECFEITAWSETQEIMGIRHREWDLEGVQFHPESILSEQGHAL
CEEEEEHHHEEECCCCCCHHEEEECCCCHHHHHCCCCCCCCCCCEEECHHHHHHHCCHHH
LENFLRR
HHHHHCC
>Mature Secondary Structure
MILLIDNYDSFTWNLYQYFCELGAEVQVRRNDALTLAHIDALNPQKIVISPGPCTPNDAG
CEEEEECCCCCHHHHHHHHHHCCCEEEEECCCCEEEEEECCCCCCEEEEECCCCCCCCCC
ISLAVIRHYAGRIPMLGVCLGHQAMAQAFGASVVRAAKVMHGKTSPVTHNGQGVFRGLPS
CHHHHHHHHHCCCCEEHHHHCHHHHHHHHHHHHHHHHHHHCCCCCCCEECCCCCCCCCCC
PLTVTRYHSLIVDPATLPECFEITAWSETQEIMGIRHREWDLEGVQFHPESILSEQGHAL
CEEEEEHHHEEECCCCCCHHEEEECCCCHHHHHCCCCCCCCCCCEEECHHHHHHHCCHHH
LENFLRR
HHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3894673; 2403545; 11677609 [H]