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The map label for this gene is argD [H]

Identifier: 29144304

GI number: 29144304

Start: 4194576

End: 4195793

Strand: Direct

Name: argD [H]

Synonym: t4037

Alternate gene names: 29144304

Gene position: 4194576-4195793 (Clockwise)

Preceding gene: 29144303

Following gene: 29144306

Centisome position: 87.53

GC content: 56.08

Gene sequence:

>1218_bases
ATGGCAACTGAACAAACGGCTATTACGCGCGCAACTTTTGATGAGGTAATTCTGCCTGTTTATGCACCGGCGGACTTTAT
TCCGGTCAAAGGTAAAGGCAGCCGCGTATGGGATCAGCAGGGCAAAGAGTATATCGATTTCGCCGGCGGGATTGCAGTGA
CTGCGCTGGGCCATTGCCATCCGGCACTGGTCGAGGCGCTGAAATCCCAGGGGGAAACCTTGTGGCATACCAGTAACGTT
TTTACCAATGAACCGGCGTTGTGTCTGGGACGTAAACTGATCGACGCCACGTTTGCCGAGCGCGTGCTGTTTATGAATTC
CGGCACCGAAGCGAACGAAACCGCTTTTAAACTGGCGCGTCATTATGCCTGCGTGCGCCATAGCCCGTTCAAAACGAAAA
TCATTGCCTTCCAGAACGCCTTTCATGGCCGTTCCTTGTTTACCGTCTCTGTAGGCGGGCAGCCGAAATATTCCGACGGC
TTTGGGCCGAAACCCGCCGATATTATTCACGTTCCCTTCAACGATCTTCATGCGGTGAAAGCGGTAATGGATGACCACAC
CTGCGCGGTGGTAGTCGAGCCGATTCAGGGTGAAGGCGGCGTGCAGGCGGCTACACCGGAATTCCTCAAAGGGTTACGCG
ACCTGTGTGACAAGCATCAGGCGTTGCTGGTGTTTGATGAAGTGCAGTGTGGGATGGGGCGCACCGGAGACCTGTTTGCC
TATATGCACTACGGCGTCACGCCGGATATCCTCACCAGCGCCAAAGCGTTAGGCGGCGGTTTTCCGGTGAGCGCCATGCT
GACCACGCAGGAGATCGCCTCGGCCTTCCATGTCGGTTCGCATGGTTCAACCTATGGCGGCAATCCGCTGGCCTGTGCGG
TGGCTGGCGCGGCATTCGATATTATTAATACGCCAGAGGTACTACAAGGCATTCACACTAAGCGGCAACAGTTTGTGCAA
CATTTGCAGGCGATTGACGAGCAATTTGACATTTTCAGCGATATTCGCGGCATGGGGCTGCTGATTGGCGCGGAACTGAA
GCCGAAGTACAAAGGTCGGGCGCGCGATTTTCTGTACGCAGGCGCGGAGGCCGGCGTGATGGTGCTCAATGCCGGAGCCG
ACGTGATGCGTTTTGCCCCGTCGCTGGTGGTGGAAGAGGCGGATATCAATGAAGGAATGCAGCGCTTTGCGCAGGCGGTA
GGGAAGGTGGTGGCCTGA

Upstream 100 bases:

>100_bases
TTCCTCCGGCGTTGATTTGTGGTTGCTATTGAGTGATTTTTTATTCATATTTTGTGATTATAATTTCACTGGCATTTCTA
CTTAACCGGGTGGTAATGAT

Downstream 100 bases:

>100_bases
TGGCGGATTGCCGGATAAGCGTAGCGCATCCGGCAGTCGGTCTTAACCTTTTGTATCCCGTAGCCGCTTACTCAGCCAGA
TACCGTGATGCGGACGCTGA

Product: bifunctional N-succinyldiaminopimelate-aminotransferase/acetylornithine transaminase protein

Products: NA

Alternate protein names: ACOAT; DapATase; Succinyldiaminopimelate transferase [H]

Number of amino acids: Translated: 405; Mature: 404

Protein sequence:

>405_residues
MATEQTAITRATFDEVILPVYAPADFIPVKGKGSRVWDQQGKEYIDFAGGIAVTALGHCHPALVEALKSQGETLWHTSNV
FTNEPALCLGRKLIDATFAERVLFMNSGTEANETAFKLARHYACVRHSPFKTKIIAFQNAFHGRSLFTVSVGGQPKYSDG
FGPKPADIIHVPFNDLHAVKAVMDDHTCAVVVEPIQGEGGVQAATPEFLKGLRDLCDKHQALLVFDEVQCGMGRTGDLFA
YMHYGVTPDILTSAKALGGGFPVSAMLTTQEIASAFHVGSHGSTYGGNPLACAVAGAAFDIINTPEVLQGIHTKRQQFVQ
HLQAIDEQFDIFSDIRGMGLLIGAELKPKYKGRARDFLYAGAEAGVMVLNAGADVMRFAPSLVVEEADINEGMQRFAQAV
GKVVA

Sequences:

>Translated_405_residues
MATEQTAITRATFDEVILPVYAPADFIPVKGKGSRVWDQQGKEYIDFAGGIAVTALGHCHPALVEALKSQGETLWHTSNV
FTNEPALCLGRKLIDATFAERVLFMNSGTEANETAFKLARHYACVRHSPFKTKIIAFQNAFHGRSLFTVSVGGQPKYSDG
FGPKPADIIHVPFNDLHAVKAVMDDHTCAVVVEPIQGEGGVQAATPEFLKGLRDLCDKHQALLVFDEVQCGMGRTGDLFA
YMHYGVTPDILTSAKALGGGFPVSAMLTTQEIASAFHVGSHGSTYGGNPLACAVAGAAFDIINTPEVLQGIHTKRQQFVQ
HLQAIDEQFDIFSDIRGMGLLIGAELKPKYKGRARDFLYAGAEAGVMVLNAGADVMRFAPSLVVEEADINEGMQRFAQAV
GKVVA
>Mature_404_residues
ATEQTAITRATFDEVILPVYAPADFIPVKGKGSRVWDQQGKEYIDFAGGIAVTALGHCHPALVEALKSQGETLWHTSNVF
TNEPALCLGRKLIDATFAERVLFMNSGTEANETAFKLARHYACVRHSPFKTKIIAFQNAFHGRSLFTVSVGGQPKYSDGF
GPKPADIIHVPFNDLHAVKAVMDDHTCAVVVEPIQGEGGVQAATPEFLKGLRDLCDKHQALLVFDEVQCGMGRTGDLFAY
MHYGVTPDILTSAKALGGGFPVSAMLTTQEIASAFHVGSHGSTYGGNPLACAVAGAAFDIINTPEVLQGIHTKRQQFVQH
LQAIDEQFDIFSDIRGMGLLIGAELKPKYKGRARDFLYAGAEAGVMVLNAGADVMRFAPSLVVEEADINEGMQRFAQAVG
KVVA

Specific function: Involved in both the arginine and lysine biosynthetic pathways [H]

COG id: COG4992

COG function: function code E; Ornithine/acetylornithine aminotransferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily [H]

Homologues:

Organism=Homo sapiens, GI4557809, Length=385, Percent_Identity=36.8831168831169, Blast_Score=239, Evalue=4e-63,
Organism=Homo sapiens, GI284507298, Length=300, Percent_Identity=36.6666666666667, Blast_Score=192, Evalue=4e-49,
Organism=Homo sapiens, GI13994255, Length=423, Percent_Identity=28.8416075650118, Blast_Score=164, Evalue=9e-41,
Organism=Homo sapiens, GI37574042, Length=401, Percent_Identity=30.1745635910224, Blast_Score=140, Evalue=2e-33,
Organism=Homo sapiens, GI226442709, Length=374, Percent_Identity=30.7486631016043, Blast_Score=130, Evalue=1e-30,
Organism=Homo sapiens, GI24119277, Length=394, Percent_Identity=28.4263959390863, Blast_Score=128, Evalue=8e-30,
Organism=Homo sapiens, GI226442705, Length=401, Percent_Identity=28.927680798005, Blast_Score=124, Evalue=1e-28,
Organism=Homo sapiens, GI188536080, Length=422, Percent_Identity=23.2227488151659, Blast_Score=86, Evalue=8e-17,
Organism=Homo sapiens, GI38679950, Length=422, Percent_Identity=23.2227488151659, Blast_Score=86, Evalue=8e-17,
Organism=Homo sapiens, GI38679946, Length=422, Percent_Identity=23.2227488151659, Blast_Score=86, Evalue=8e-17,
Organism=Escherichia coli, GI1789759, Length=404, Percent_Identity=91.3366336633663, Blast_Score=774, Evalue=0.0,
Organism=Escherichia coli, GI1788044, Length=398, Percent_Identity=61.0552763819096, Blast_Score=518, Evalue=1e-148,
Organism=Escherichia coli, GI1789016, Length=404, Percent_Identity=35.6435643564356, Blast_Score=231, Evalue=6e-62,
Organism=Escherichia coli, GI1787560, Length=403, Percent_Identity=32.7543424317618, Blast_Score=197, Evalue=8e-52,
Organism=Escherichia coli, GI145693181, Length=393, Percent_Identity=33.8422391857506, Blast_Score=191, Evalue=6e-50,
Organism=Escherichia coli, GI1786991, Length=415, Percent_Identity=30.6024096385542, Blast_Score=137, Evalue=1e-33,
Organism=Escherichia coli, GI1786349, Length=311, Percent_Identity=31.8327974276527, Blast_Score=123, Evalue=3e-29,
Organism=Caenorhabditis elegans, GI25144271, Length=376, Percent_Identity=38.563829787234, Blast_Score=245, Evalue=4e-65,
Organism=Caenorhabditis elegans, GI32564660, Length=432, Percent_Identity=28.7037037037037, Blast_Score=180, Evalue=1e-45,
Organism=Caenorhabditis elegans, GI25144274, Length=269, Percent_Identity=37.9182156133829, Blast_Score=180, Evalue=1e-45,
Organism=Caenorhabditis elegans, GI71992977, Length=427, Percent_Identity=27.8688524590164, Blast_Score=140, Evalue=1e-33,
Organism=Caenorhabditis elegans, GI17541228, Length=425, Percent_Identity=24.9411764705882, Blast_Score=96, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI71981843, Length=165, Percent_Identity=35.1515151515151, Blast_Score=92, Evalue=5e-19,
Organism=Saccharomyces cerevisiae, GI6324432, Length=399, Percent_Identity=38.5964912280702, Blast_Score=283, Evalue=3e-77,
Organism=Saccharomyces cerevisiae, GI6323470, Length=403, Percent_Identity=34.4913151364764, Blast_Score=226, Evalue=7e-60,
Organism=Saccharomyces cerevisiae, GI6324386, Length=334, Percent_Identity=28.7425149700599, Blast_Score=107, Evalue=2e-24,
Organism=Saccharomyces cerevisiae, GI6321456, Length=448, Percent_Identity=24.5535714285714, Blast_Score=90, Evalue=5e-19,
Organism=Drosophila melanogaster, GI21357415, Length=378, Percent_Identity=36.2433862433862, Blast_Score=229, Evalue=3e-60,
Organism=Drosophila melanogaster, GI28574759, Length=421, Percent_Identity=28.7410926365796, Blast_Score=177, Evalue=1e-44,
Organism=Drosophila melanogaster, GI161085790, Length=416, Percent_Identity=28.6057692307692, Blast_Score=174, Evalue=9e-44,
Organism=Drosophila melanogaster, GI21356575, Length=361, Percent_Identity=31.0249307479224, Blast_Score=147, Evalue=1e-35,
Organism=Drosophila melanogaster, GI281366494, Length=434, Percent_Identity=23.0414746543779, Blast_Score=101, Evalue=8e-22,
Organism=Drosophila melanogaster, GI24667139, Length=434, Percent_Identity=23.0414746543779, Blast_Score=101, Evalue=8e-22,
Organism=Drosophila melanogaster, GI24667143, Length=434, Percent_Identity=23.0414746543779, Blast_Score=101, Evalue=8e-22,

Paralogues:

None

Copy number: 200 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004636
- InterPro:   IPR005814
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422
- InterPro:   IPR017652 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: =2.6.1.11; =2.6.1.17 [H]

Molecular weight: Translated: 43584; Mature: 43453

Theoretical pI: Translated: 6.34; Mature: 6.34

Prosite motif: PS00600 AA_TRANSFER_CLASS_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATEQTAITRATFDEVILPVYAPADFIPVKGKGSRVWDQQGKEYIDFAGGIAVTALGHCH
CCCCHHHHHHHHHHHHHEEEECCCCEEEECCCCCCCHHHCCCHHHHHCCCHHEEHHHCCC
PALVEALKSQGETLWHTSNVFTNEPALCLGRKLIDATFAERVLFMNSGTEANETAFKLAR
HHHHHHHHHCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHEEEECCCCCCHHHHHHHHH
HYACVRHSPFKTKIIAFQNAFHGRSLFTVSVGGQPKYSDGFGPKPADIIHVPFNDLHAVK
HHHHHCCCCCCEEEEEEECCCCCCEEEEEEECCCCCCCCCCCCCCCCEEECCCHHHHHHH
AVMDDHTCAVVVEPIQGEGGVQAATPEFLKGLRDLCDKHQALLVFDEVQCGMGRTGDLFA
HHHCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHCCCCEEEEEEEHHCCCCCCCCEEE
YMHYGVTPDILTSAKALGGGFPVSAMLTTQEIASAFHVGSHGSTYGGNPLACAVAGAAFD
EEECCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEHHHHHC
IINTPEVLQGIHTKRQQFVQHLQAIDEQFDIFSDIRGMGLLIGAELKPKYKGRARDFLYA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCHHHEEE
GAEAGVMVLNAGADVMRFAPSLVVEEADINEGMQRFAQAVGKVVA
CCCCCEEEEECCCHHHHHCHHHEEECCHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
ATEQTAITRATFDEVILPVYAPADFIPVKGKGSRVWDQQGKEYIDFAGGIAVTALGHCH
CCCHHHHHHHHHHHHHEEEECCCCEEEECCCCCCCHHHCCCHHHHHCCCHHEEHHHCCC
PALVEALKSQGETLWHTSNVFTNEPALCLGRKLIDATFAERVLFMNSGTEANETAFKLAR
HHHHHHHHHCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHEEEECCCCCCHHHHHHHHH
HYACVRHSPFKTKIIAFQNAFHGRSLFTVSVGGQPKYSDGFGPKPADIIHVPFNDLHAVK
HHHHHCCCCCCEEEEEEECCCCCCEEEEEEECCCCCCCCCCCCCCCCEEECCCHHHHHHH
AVMDDHTCAVVVEPIQGEGGVQAATPEFLKGLRDLCDKHQALLVFDEVQCGMGRTGDLFA
HHHCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHCCCCEEEEEEEHHCCCCCCCCEEE
YMHYGVTPDILTSAKALGGGFPVSAMLTTQEIASAFHVGSHGSTYGGNPLACAVAGAAFD
EEECCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEHHHHHC
IINTPEVLQGIHTKRQQFVQHLQAIDEQFDIFSDIRGMGLLIGAELKPKYKGRARDFLYA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCHHHEEE
GAEAGVMVLNAGADVMRFAPSLVVEEADINEGMQRFAQAVGKVVA
CCCCCEEEEECCCHHHHHCHHHEEECCHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]