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The map label for this gene is tctE [H]

Identifier: 29143046

GI number: 29143046

Start: 2771279

End: 2772694

Strand: Reverse

Name: tctE [H]

Synonym: t2678

Alternate gene names: 29143046

Gene position: 2772694-2771279 (Counterclockwise)

Preceding gene: 29143047

Following gene: 29143043

Centisome position: 57.86

GC content: 56.14

Gene sequence:

>1416_bases
ATGAAGTGGGTTAAGCCGCAATCGTTGTACCTGCAACTCTTACTGTTCCTGGGGTTGCCGCTGATTCTGCTATGGGGGCT
GTCGGCGTTTAACAGTTATGTCAATGCGCTACAGGCCGCCACTCAGGCTTATGATCGTACGTTGCTCTCCTCGGCGCGAA
CGGTATCGGAACGGCTGGTGGTGCGCAATAACCATCTGGAAGTTAACGTGCCCTGGGTGGTGCTGGATAGCTTCGAGCTT
AATATGAATGATCGACTCTATTACAAAGTCGTCGACCCTTCCGGGAAGGTCATTTCCGGTTATGACGATCTGCCTGCCAT
GCCGCCCGCTACGCCCCGTACCCGGCTTTATCCGGCGCTGGCGTGGTTCTATCATACCGAGTATCGCGGCGAGGCGATCC
GCGTAGCGCGTTTGCTACAGCCGGTCAACGAAGGCGGCATTATCGGCATGGCGGAGGTTTATGTCGCAGAAACGCTGCAG
TCCCGTCGTTATCTGGCGGGCCAACTGCTGTTCTCTTCCTGGATCTCACAGGGGCTGCTGGTGTTGCTGACCCTGGTGCT
GGTTGGCTGGTTATTACGCCGGATCCTGCGCCCTATGCGTCAACTTTCGTCATTAATGGTACGCCGCGAACCGGGTCTGT
TAACGCCGCTGCCGGAACTGCTGCCGTGGTCGGAAACACGCTTGTTAATCGTGGCGTTTAATCGCTACATTGACAGGCTC
CGCGGCATCCTTTCCCGGCAGGAACGCTTTAGCGCCGATGCTTCTCACCAGTTAAAAACGCCGCTGGCGGTGTTAAAAAC
GCAGGCGGCGGTGGCGTTAGCCAGCCAGCACCCTCATCACTGGTACGAAAGTCTGCAGGCGATGAGCGTAACGCTGGATA
GCACCATTCAGCTCACGGAAAGATTGTTGCAACTTTCTGCGGTAAAGCATAAAGAGCAGGGCGAGAGGCGTTTTTCCCCG
GTGAATCTGTACGATATCGTACAGAGCGGCTGCTTTACCCGCCTGGCGCAGGCGCGCAGTAAACATATCGACCTGGGCTA
CGAAGGCGAACAGGAAGCGATGTGGATCGAGGGGGATGAGGTACTGCTTAGCGAGCTGTGCGGAAACTTGCTGGATAATG
CGCTGAAATACACGCCTGAGCAAGGCATTGTCACCGCGCGGCTTGAACGGGATGGCGATGCCGTGACGCTGGTTGTCGAA
GATAGCGGCCCCGGCATTGATAATGAACACATCCATCTGGCGCTACAGCCGTTCCACCGGCTCGATAACGTAGGAAATGT
GGCCGGGGCGGGCATTGGTCTGGCTTTGGTCAATGATATCGCACGCTTGCACCGTACTCATCCCCATTTTTCCCGTAGCG
AAGCGTTGGGAGGGTTATACGTTCGGATACGCTTTTTAAGCCTTGTCCCGCAGTAA

Upstream 100 bases:

>100_bases
AGCATCGAACTTTATATTCATCGACTGCGTAAAAAACTTCAGGGAAGCGATGTACGAATTACGACGCTGCGCGGCCTGGG
TTATGTGCTGGAGCGCGGCG

Downstream 100 bases:

>100_bases
TGCGCACAAATGTGTCAGCGGTAAAGCACGTTTACAAAAAGTCGCATCTTGAGGTGTGACGTTTTAATCAAATGATCATA
CATTCCCCCTACAAACCGTA

Product: two-component system sensor kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 471; Mature: 471

Protein sequence:

>471_residues
MKWVKPQSLYLQLLLFLGLPLILLWGLSAFNSYVNALQAATQAYDRTLLSSARTVSERLVVRNNHLEVNVPWVVLDSFEL
NMNDRLYYKVVDPSGKVISGYDDLPAMPPATPRTRLYPALAWFYHTEYRGEAIRVARLLQPVNEGGIIGMAEVYVAETLQ
SRRYLAGQLLFSSWISQGLLVLLTLVLVGWLLRRILRPMRQLSSLMVRREPGLLTPLPELLPWSETRLLIVAFNRYIDRL
RGILSRQERFSADASHQLKTPLAVLKTQAAVALASQHPHHWYESLQAMSVTLDSTIQLTERLLQLSAVKHKEQGERRFSP
VNLYDIVQSGCFTRLAQARSKHIDLGYEGEQEAMWIEGDEVLLSELCGNLLDNALKYTPEQGIVTARLERDGDAVTLVVE
DSGPGIDNEHIHLALQPFHRLDNVGNVAGAGIGLALVNDIARLHRTHPHFSRSEALGGLYVRIRFLSLVPQ

Sequences:

>Translated_471_residues
MKWVKPQSLYLQLLLFLGLPLILLWGLSAFNSYVNALQAATQAYDRTLLSSARTVSERLVVRNNHLEVNVPWVVLDSFEL
NMNDRLYYKVVDPSGKVISGYDDLPAMPPATPRTRLYPALAWFYHTEYRGEAIRVARLLQPVNEGGIIGMAEVYVAETLQ
SRRYLAGQLLFSSWISQGLLVLLTLVLVGWLLRRILRPMRQLSSLMVRREPGLLTPLPELLPWSETRLLIVAFNRYIDRL
RGILSRQERFSADASHQLKTPLAVLKTQAAVALASQHPHHWYESLQAMSVTLDSTIQLTERLLQLSAVKHKEQGERRFSP
VNLYDIVQSGCFTRLAQARSKHIDLGYEGEQEAMWIEGDEVLLSELCGNLLDNALKYTPEQGIVTARLERDGDAVTLVVE
DSGPGIDNEHIHLALQPFHRLDNVGNVAGAGIGLALVNDIARLHRTHPHFSRSEALGGLYVRIRFLSLVPQ
>Mature_471_residues
MKWVKPQSLYLQLLLFLGLPLILLWGLSAFNSYVNALQAATQAYDRTLLSSARTVSERLVVRNNHLEVNVPWVVLDSFEL
NMNDRLYYKVVDPSGKVISGYDDLPAMPPATPRTRLYPALAWFYHTEYRGEAIRVARLLQPVNEGGIIGMAEVYVAETLQ
SRRYLAGQLLFSSWISQGLLVLLTLVLVGWLLRRILRPMRQLSSLMVRREPGLLTPLPELLPWSETRLLIVAFNRYIDRL
RGILSRQERFSADASHQLKTPLAVLKTQAAVALASQHPHHWYESLQAMSVTLDSTIQLTERLLQLSAVKHKEQGERRFSP
VNLYDIVQSGCFTRLAQARSKHIDLGYEGEQEAMWIEGDEVLLSELCGNLLDNALKYTPEQGIVTARLERDGDAVTLVVE
DSGPGIDNEHIHLALQPFHRLDNVGNVAGAGIGLALVNDIARLHRTHPHFSRSEALGGLYVRIRFLSLVPQ

Specific function: Member of a two-component regulatory system qseB/qseC. May activate qseB by phosphorylation [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1789403, Length=301, Percent_Identity=30.8970099667774, Blast_Score=108, Evalue=9e-25,
Organism=Escherichia coli, GI1790551, Length=283, Percent_Identity=28.6219081272085, Blast_Score=96, Evalue=4e-21,
Organism=Escherichia coli, GI1786783, Length=292, Percent_Identity=27.7397260273973, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI1790861, Length=282, Percent_Identity=28.7234042553192, Blast_Score=89, Evalue=8e-19,
Organism=Escherichia coli, GI1786600, Length=261, Percent_Identity=27.2030651340996, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1788279, Length=300, Percent_Identity=27.6666666666667, Blast_Score=75, Evalue=9e-15,
Organism=Escherichia coli, GI1788393, Length=258, Percent_Identity=26.7441860465116, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1790346, Length=273, Percent_Identity=26.7399267399267, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1789808, Length=299, Percent_Identity=25.752508361204, Blast_Score=66, Evalue=4e-12,
Organism=Escherichia coli, GI1787894, Length=217, Percent_Identity=27.6497695852535, Blast_Score=65, Evalue=8e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 53114; Mature: 53114

Theoretical pI: Translated: 8.23; Mature: 8.23

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKWVKPQSLYLQLLLFLGLPLILLWGLSAFNSYVNALQAATQAYDRTLLSSARTVSERLV
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VRNNHLEVNVPWVVLDSFELNMNDRLYYKVVDPSGKVISGYDDLPAMPPATPRTRLYPAL
EECCEEEEEECEEEEEEEEECCCCEEEEEEECCCCCEEECCCCCCCCCCCCCCHHHHHHH
AWFYHTEYRGEAIRVARLLQPVNEGGIIGMAEVYVAETLQSRRYLAGQLLFSSWISQGLL
HHHHHHHHCCHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VLLTLVLVGWLLRRILRPMRQLSSLMVRREPGLLTPLPELLPWSETRLLIVAFNRYIDRL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHCCCCCCEEEEHHHHHHHHHH
RGILSRQERFSADASHQLKTPLAVLKTQAAVALASQHPHHWYESLQAMSVTLDSTIQLTE
HHHHHHHHHHCCCCCHHHHCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
RLLQLSAVKHKEQGERRFSPVNLYDIVQSGCFTRLAQARSKHIDLGYEGEQEAMWIEGDE
HHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEECCHH
VLLSELCGNLLDNALKYTPEQGIVTARLERDGDAVTLVVEDSGPGIDNEHIHLALQPFHR
HHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCEEEEEEECCCCCCCCCEEEEEEEHHHH
LDNVGNVAGAGIGLALVNDIARLHRTHPHFSRSEALGGLYVRIRFLSLVPQ
HCCCCCHHCCHHHHHHHHHHHHHHHCCCCCCHHHHCCHHHHHHHHHHHCCC
>Mature Secondary Structure
MKWVKPQSLYLQLLLFLGLPLILLWGLSAFNSYVNALQAATQAYDRTLLSSARTVSERLV
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VRNNHLEVNVPWVVLDSFELNMNDRLYYKVVDPSGKVISGYDDLPAMPPATPRTRLYPAL
EECCEEEEEECEEEEEEEEECCCCEEEEEEECCCCCEEECCCCCCCCCCCCCCHHHHHHH
AWFYHTEYRGEAIRVARLLQPVNEGGIIGMAEVYVAETLQSRRYLAGQLLFSSWISQGLL
HHHHHHHHCCHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VLLTLVLVGWLLRRILRPMRQLSSLMVRREPGLLTPLPELLPWSETRLLIVAFNRYIDRL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHCCCCCCEEEEHHHHHHHHHH
RGILSRQERFSADASHQLKTPLAVLKTQAAVALASQHPHHWYESLQAMSVTLDSTIQLTE
HHHHHHHHHHCCCCCHHHHCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
RLLQLSAVKHKEQGERRFSPVNLYDIVQSGCFTRLAQARSKHIDLGYEGEQEAMWIEGDE
HHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEECCHH
VLLSELCGNLLDNALKYTPEQGIVTARLERDGDAVTLVVEDSGPGIDNEHIHLALQPFHR
HHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCEEEEEEECCCCCCCCCEEEEEEEHHHH
LDNVGNVAGAGIGLALVNDIARLHRTHPHFSRSEALGGLYVRIRFLSLVPQ
HCCCCCHHCCHHHHHHHHHHHHHHHCCCCCCHHHHCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800; 10675023 [H]