Click here to switch to the map view.

The map label for this gene is pipB2 [H]

Identifier: 29143043

GI number: 29143043

Start: 2765723

End: 2766775

Strand: Reverse

Name: pipB2 [H]

Synonym: t2674

Alternate gene names: 29143043

Gene position: 2766775-2765723 (Counterclockwise)

Preceding gene: 29143046

Following gene: 229220624

Centisome position: 57.74

GC content: 43.97

Gene sequence:

>1053_bases
ATGCAGCGTTCACTCGATAGTCTGGCTGGTATGGCTACATCTGCTTTTGGCGCGGGGACTTCTGCTGCTATGCGGCAAGC
TACCTCGCCCAAAACCATTCTGCAACATATCATTAACTTTTTTACCTGTGGTGGGATACGTCGGAGAAATGAAACACAAT
ATCAGGAATTGATAGAGACTATGGCTGAAACATTGAAAAGTTCAATGTCTGACAGAGGTGCTCCGTTGCCAGAAAACATC
ATCCTGGATGATGTGGATGGGTGTCGTGTCGAATTTAATCTTCCTGGTGAGAATAACGAAGCTGGACAAGTTATTGTACG
AGTCAGTAAAGGCGACAATTCTGAGACAAGAGAAATTCCGCTTGCCTCTTTTGAAAAAATATGTCGAGCTTTACTATTCA
GATGCGAATTTTCTCTTCCTCAGGATTCTGTAATATTAACTGCCCAGGGAGGCATGAATCTTAAAGGCGCTGTCCTTACC
GGAGCAAATCTGACGGCAGAAAATTTATGTGACGCAGACTTAAGCGGCGCAGATTTAGAGGGGGCAATACTGTTTATGGC
GGATTGTGACGGTGCAAATTTTAAGGGCGCAAATCTATCGGGAGCATCATTAGGCGACAGTAACTTAACGAACGCCTGTC
TGGAAGATAGTATTATGTGTGGCGCTACCCTCGATCGCGCTAATCTTACTGGCGCCAATTTACAACACACAAGTCTGTTA
GGCTGTAGCATGGTAGAATGTAATTGTTCCGGTGCGAATATGGATCACGCTAATGTTTCAGGCTCAACCCTTATACGTGC
CGATATGAGCGGTGCGACATTAAAGGGTGCTACTATAATGGCTGCTATTATGGAAGGCGCTGTCTTAACTCGGGCAAACC
TGCAAAAGGCTAGTTTTACTGCTACGAACCTGGACGGGGCTGATTTGTCTGAGGCTAATTTAAGAAATACCAGTTTTAAA
GATTGTACACTAACCGATTTGCGTACCGAAGACGCCACAATGTCTACAAGTACACAAACACTTTTTAACGTATTTTATAG
TGAAAATATTTAG

Upstream 100 bases:

>100_bases
TATGTAACCAGACGCAAAGGGGGTATTCACCTTATTTCTAAATGCAAATCTAATGATAAATTTTATCATGTACTGTGTTG
CTCTCTCTGGGAGAAAATAT

Downstream 100 bases:

>100_bases
CCCTATTTGACGTAAATCTGAAATAAAAGCAATGTAAGAATAACAATCTGCTACTGAATAGTAGCTGAGAGTTAATTATT
TACAGTATCTTTTATTATTA

Product: hypothetical protein

Products: NA

Alternate protein names: Type III effector pipB2 [H]

Number of amino acids: Translated: 350; Mature: 350

Protein sequence:

>350_residues
MQRSLDSLAGMATSAFGAGTSAAMRQATSPKTILQHIINFFTCGGIRRRNETQYQELIETMAETLKSSMSDRGAPLPENI
ILDDVDGCRVEFNLPGENNEAGQVIVRVSKGDNSETREIPLASFEKICRALLFRCEFSLPQDSVILTAQGGMNLKGAVLT
GANLTAENLCDADLSGADLEGAILFMADCDGANFKGANLSGASLGDSNLTNACLEDSIMCGATLDRANLTGANLQHTSLL
GCSMVECNCSGANMDHANVSGSTLIRADMSGATLKGATIMAAIMEGAVLTRANLQKASFTATNLDGADLSEANLRNTSFK
DCTLTDLRTEDATMSTSTQTLFNVFYSENI

Sequences:

>Translated_350_residues
MQRSLDSLAGMATSAFGAGTSAAMRQATSPKTILQHIINFFTCGGIRRRNETQYQELIETMAETLKSSMSDRGAPLPENI
ILDDVDGCRVEFNLPGENNEAGQVIVRVSKGDNSETREIPLASFEKICRALLFRCEFSLPQDSVILTAQGGMNLKGAVLT
GANLTAENLCDADLSGADLEGAILFMADCDGANFKGANLSGASLGDSNLTNACLEDSIMCGATLDRANLTGANLQHTSLL
GCSMVECNCSGANMDHANVSGSTLIRADMSGATLKGATIMAAIMEGAVLTRANLQKASFTATNLDGADLSEANLRNTSFK
DCTLTDLRTEDATMSTSTQTLFNVFYSENI
>Mature_350_residues
MQRSLDSLAGMATSAFGAGTSAAMRQATSPKTILQHIINFFTCGGIRRRNETQYQELIETMAETLKSSMSDRGAPLPENI
ILDDVDGCRVEFNLPGENNEAGQVIVRVSKGDNSETREIPLASFEKICRALLFRCEFSLPQDSVILTAQGGMNLKGAVLT
GANLTAENLCDADLSGADLEGAILFMADCDGANFKGANLSGASLGDSNLTNACLEDSIMCGATLDRANLTGANLQHTSLL
GCSMVECNCSGANMDHANVSGSTLIRADMSGATLKGATIMAAIMEGAVLTRANLQKASFTATNLDGADLSEANLRNTSFK
DCTLTDLRTEDATMSTSTQTLFNVFYSENI

Specific function: Effector proteins function to alter host cell physiology and promote bacterial survival in host tissues. Involved in the reorganization of late endosome/lysosome (LE/Lys) compartments in mammalian cells. Necessary and sufficient to link kinesin-1 onto the

COG id: COG1357

COG function: function code S; Uncharacterized low-complexity proteins

Gene ontology:

Cell location: Secreted. Host membrane (By similarity). Note=Secreted via the type III secretion system 2 (SPI-2 TTSS), and delivered into the host cell (By similarity) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 4 pentapeptide repeat domains [H]

Homologues:

Organism=Homo sapiens, GI39753959, Length=169, Percent_Identity=34.3195266272189, Blast_Score=76, Evalue=4e-14,
Organism=Drosophila melanogaster, GI221377802, Length=157, Percent_Identity=35.031847133758, Blast_Score=77, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001646 [H]

Pfam domain/function: PF00805 Pentapeptide [H]

EC number: NA

Molecular weight: Translated: 36997; Mature: 36997

Theoretical pI: Translated: 4.31; Mature: 4.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.4 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
7.4 %Cys+Met (Translated Protein)
3.4 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
7.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQRSLDSLAGMATSAFGAGTSAAMRQATSPKTILQHIINFFTCGGIRRRNETQYQELIET
CCCCHHHHHHHHHHHCCCCCHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHH
MAETLKSSMSDRGAPLPENIILDDVDGCRVEFNLPGENNEAGQVIVRVSKGDNSETREIP
HHHHHHHHHHHCCCCCCCCCEEECCCCCEEEEECCCCCCCCCEEEEEEECCCCCCCCCCC
LASFEKICRALLFRCEFSLPQDSVILTAQGGMNLKGAVLTGANLTAENLCDADLSGADLE
HHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCEEEEECCCCCHHHCCCCCCCCCCCC
GAILFMADCDGANFKGANLSGASLGDSNLTNACLEDSIMCGATLDRANLTGANLQHTSLL
CEEEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHCCEEECCEECCCCCCCCCCCHHHCC
GCSMVECNCSGANMDHANVSGSTLIRADMSGATLKGATIMAAIMEGAVLTRANLQKASFT
CCEEEEECCCCCCCCCCCCCCCEEEEECCCCCEECHHHHHHHHHHCHHEECCCCCCCEEE
ATNLDGADLSEANLRNTSFKDCTLTDLRTEDATMSTSTQTLFNVFYSENI
ECCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCHHHHHHHHHHHCCC
>Mature Secondary Structure
MQRSLDSLAGMATSAFGAGTSAAMRQATSPKTILQHIINFFTCGGIRRRNETQYQELIET
CCCCHHHHHHHHHHHCCCCCHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHH
MAETLKSSMSDRGAPLPENIILDDVDGCRVEFNLPGENNEAGQVIVRVSKGDNSETREIP
HHHHHHHHHHHCCCCCCCCCEEECCCCCEEEEECCCCCCCCCEEEEEEECCCCCCCCCCC
LASFEKICRALLFRCEFSLPQDSVILTAQGGMNLKGAVLTGANLTAENLCDADLSGADLE
HHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCEEEEECCCCCHHHCCCCCCCCCCCC
GAILFMADCDGANFKGANLSGASLGDSNLTNACLEDSIMCGATLDRANLTGANLQHTSLL
CEEEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHCCEEECCEECCCCCCCCCCCHHHCC
GCSMVECNCSGANMDHANVSGSTLIRADMSGATLKGATIMAAIMEGAVLTRANLQKASFT
CCEEEEECCCCCCCCCCCCCCCEEEEECCCCCEECHHHHHHHHHHCHHEECCCCCCCEEE
ATNLDGADLSEANLRNTSFKDCTLTDLRTEDATMSTSTQTLFNVFYSENI
ECCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA