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The map label for this gene is tctD [H]

Identifier: 29143047

GI number: 29143047

Start: 2772681

End: 2773355

Strand: Reverse

Name: tctD [H]

Synonym: t2679

Alternate gene names: 29143047

Gene position: 2773355-2772681 (Counterclockwise)

Preceding gene: 29143057

Following gene: 29143046

Centisome position: 57.88

GC content: 54.81

Gene sequence:

>675_bases
ATGCGTCTCTTATTGGCGGAAGATAACCGTGAGCTGGCTCACTGGCTGGAGAAAGCGCTGGTGCAAAACGGCTTTGCCGT
GGACTGCGTATTTGACGGCCTGGCGGCTGACCATCTTCTGCACAGTGAAATGTATGCGCTGATGGTGCTGGATATCAATA
TGCCGGGAATGGATGGACTGGAGGTGGTGCAACGGCTGCGTAAACGCGGTCAGACCTTGCCCGTTTTGCTGCTCACGGCG
CGAAGCGCGGTGGCGGATCGCGTAAAAGGTCTCAACGTCGGCGCGGATGACTATCTGCCGAAACCCTTTGAACTGGAAGA
GCTGGATGCCCGTTTACGGGCCTTGCTCCGACGCAGCGCTGGGCTGGTTCATGAAGTTCAGCAACTGGGTGAATTGATCT
TTCATGATGAAGGGTATTTTCTGTTACAGGGACAGCCGTTAGCGCTGACGCCGCGTGAGCAGGCGCTCTTAACCGTATTG
ATGTACCGACGAACGCGGCCTGTCTCGCGTCAGCAGCTTTTTGAACAGGTGTTCAGCCTGAACGATGAGGTAAGCCCTGA
AAGCATCGAACTTTATATTCATCGACTGCGTAAAAAACTTCAGGGAAGCGATGTACGAATTACGACGCTGCGCGGCCTGG
GTTATGTGCTGGAGCGCGGCGATGAAGTGGGTTAA

Upstream 100 bases:

>100_bases
TGATTATGTGAGCCGACATGTAGCAGTTCGGTTGCGTGATTGTTAAAACAATAACCTTTCAATTCCCTTTCAATGCGGCA
GAAACTTTACAGGATGTGAT

Downstream 100 bases:

>100_bases
GCCGCAATCGTTGTACCTGCAACTCTTACTGTTCCTGGGGTTGCCGCTGATTCTGCTATGGGGGCTGTCGGCGTTTAACA
GTTATGTCAATGCGCTACAG

Product: transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 224; Mature: 224

Protein sequence:

>224_residues
MRLLLAEDNRELAHWLEKALVQNGFAVDCVFDGLAADHLLHSEMYALMVLDINMPGMDGLEVVQRLRKRGQTLPVLLLTA
RSAVADRVKGLNVGADDYLPKPFELEELDARLRALLRRSAGLVHEVQQLGELIFHDEGYFLLQGQPLALTPREQALLTVL
MYRRTRPVSRQQLFEQVFSLNDEVSPESIELYIHRLRKKLQGSDVRITTLRGLGYVLERGDEVG

Sequences:

>Translated_224_residues
MRLLLAEDNRELAHWLEKALVQNGFAVDCVFDGLAADHLLHSEMYALMVLDINMPGMDGLEVVQRLRKRGQTLPVLLLTA
RSAVADRVKGLNVGADDYLPKPFELEELDARLRALLRRSAGLVHEVQQLGELIFHDEGYFLLQGQPLALTPREQALLTVL
MYRRTRPVSRQQLFEQVFSLNDEVSPESIELYIHRLRKKLQGSDVRITTLRGLGYVLERGDEVG
>Mature_224_residues
MRLLLAEDNRELAHWLEKALVQNGFAVDCVFDGLAADHLLHSEMYALMVLDINMPGMDGLEVVQRLRKRGQTLPVLLLTA
RSAVADRVKGLNVGADDYLPKPFELEELDARLRALLRRSAGLVHEVQQLGELIFHDEGYFLLQGQPLALTPREQALLTVL
MYRRTRPVSRQQLFEQVFSLNDEVSPESIELYIHRLRKKLQGSDVRITTLRGLGYVLERGDEVG

Specific function: Transcriptional activator of the tctI tricarboxylate transport system operon [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789402, Length=219, Percent_Identity=42.4657534246575, Blast_Score=164, Evalue=3e-42,
Organism=Escherichia coli, GI1790552, Length=228, Percent_Identity=41.6666666666667, Blast_Score=162, Evalue=2e-41,
Organism=Escherichia coli, GI1786784, Length=226, Percent_Identity=37.6106194690265, Blast_Score=140, Evalue=9e-35,
Organism=Escherichia coli, GI87082012, Length=217, Percent_Identity=36.8663594470046, Blast_Score=137, Evalue=8e-34,
Organism=Escherichia coli, GI1789809, Length=227, Percent_Identity=35.2422907488987, Blast_Score=127, Evalue=6e-31,
Organism=Escherichia coli, GI1787375, Length=229, Percent_Identity=34.9344978165939, Blast_Score=126, Evalue=1e-30,
Organism=Escherichia coli, GI1786599, Length=220, Percent_Identity=36.3636363636364, Blast_Score=122, Evalue=2e-29,
Organism=Escherichia coli, GI1790860, Length=224, Percent_Identity=35.7142857142857, Blast_Score=110, Evalue=7e-26,
Organism=Escherichia coli, GI2367329, Length=234, Percent_Identity=38.034188034188, Blast_Score=102, Evalue=2e-23,
Organism=Escherichia coli, GI1788394, Length=223, Percent_Identity=32.2869955156951, Blast_Score=97, Evalue=6e-22,
Organism=Escherichia coli, GI1786911, Length=222, Percent_Identity=31.0810810810811, Blast_Score=92, Evalue=3e-20,
Organism=Escherichia coli, GI1787229, Length=226, Percent_Identity=30.5309734513274, Blast_Score=87, Evalue=7e-19,
Organism=Escherichia coli, GI1788550, Length=108, Percent_Identity=35.1851851851852, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI1788713, Length=115, Percent_Identity=35.6521739130435, Blast_Score=73, Evalue=1e-14,
Organism=Escherichia coli, GI1790863, Length=226, Percent_Identity=26.5486725663717, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI1790299, Length=126, Percent_Identity=33.3333333333333, Blast_Score=72, Evalue=4e-14,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 25453; Mature: 25453

Theoretical pI: Translated: 5.97; Mature: 5.97

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00217 SUGAR_TRANSPORT_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLLLAEDNRELAHWLEKALVQNGFAVDCVFDGLAADHLLHSEMYALMVLDINMPGMDGL
CEEEEECCCHHHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHHEEEEEEECCCCCCHH
EVVQRLRKRGQTLPVLLLTARSAVADRVKGLNVGADDYLPKPFELEELDARLRALLRRSA
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHC
GLVHEVQQLGELIFHDEGYFLLQGQPLALTPREQALLTVLMYRRTRPVSRQQLFEQVFSL
HHHHHHHHHHHHHCCCCCEEEECCCCEEECCHHHHHHHHHHHHHCCCCHHHHHHHHHHCC
NDEVSPESIELYIHRLRKKLQGSDVRITTLRGLGYVLERGDEVG
CCCCCHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHCCCCCC
>Mature Secondary Structure
MRLLLAEDNRELAHWLEKALVQNGFAVDCVFDGLAADHLLHSEMYALMVLDINMPGMDGL
CEEEEECCCHHHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHHEEEEEEECCCCCCHH
EVVQRLRKRGQTLPVLLLTARSAVADRVKGLNVGADDYLPKPFELEELDARLRALLRRSA
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHC
GLVHEVQQLGELIFHDEGYFLLQGQPLALTPREQALLTVLMYRRTRPVSRQQLFEQVFSL
HHHHHHHHHHHHHCCCCCEEEECCCCEEECCHHHHHHHHHHHHHCCCCHHHHHHHHHHCC
NDEVSPESIELYIHRLRKKLQGSDVRITTLRGLGYVLERGDEVG
CCCCCHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2666399; 11083839; 11677609 [H]