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The map label for this gene is nikC [C]

Identifier: 29141605

GI number: 29141605

Start: 1208888

End: 1209700

Strand: Direct

Name: nikC [C]

Synonym: t1134

Alternate gene names: 29141605

Gene position: 1208888-1209700 (Clockwise)

Preceding gene: 29141604

Following gene: 29141606

Centisome position: 25.23

GC content: 56.58

Gene sequence:

>813_bases
ATGCTCTATAATCCTGCCCCGACGTTGTTTCGTCTGCTCCTCTCCGTTACCTGTCTGCTGTTTATTGCCGGATACGGTTA
TGCCACGTTGAGCCAGCCGCCAGAGGTTAATCTGCTTGCCCGGCATCTGTCGCCTGATATCCAGCACTGGTTTGGCACCG
ATAATCTGGGGCGCGATGTATGGCTTCGTTGCTTTCAGGGGGCCTTCACCAGTTTACAAATTGGCGTTGGCGCCGCGCTG
TGCAGCGGCGTTATCGCGTTAGTGATGGCGGCAGTGGCGCGCATTCATCCCCGGCTGGACCTCCTGGTGCGGCTGATAAC
CGATGCTATGCTCGCCATGCCGCATTTACTTTTGCTGATCCTTATCTGTTTTACGCTCGGCGGCGGTAAAAGCGGCGTCA
TTGCGGCCGTGGCGTTAACGCACTGGCCCCGTCTGGCGCTGATTCTGCGCGCCGACGCGGAGCGGGTAGCGCAGAGTGAC
TACCTGACATTGACCTATCGTCTGGGGCATGGACACCTTTATTGCTGGCGATATCACTATTTTCCGGCGCTATTGCCGCA
ATGGTTGACGGGAACGTTATTGATGTTTCCTCATGCGGTATTGCACAGCGCGGCGTTAAGTTTTCTGGGGTTTGGGCTGG
CGCCGCATGAGCCTTCGCTGGGGCTGTTGCTGGCGGATGCGTTACGGTTTATTAGCCATGGAAACTGGTGGCTGGTGCTA
TTTCCCGGCCTAATGTTATTCACGCTGGTGATGCTCTTCGATCAGTTTGCGCGCGCCATTCAGCGGCTGTGGCTAAGGAG
TGACGTATGCTGA

Upstream 100 bases:

>100_bases
CTCATGGGGATCGTTTTATTCTGTACGCTATTAGTGTTTGCCGGAAATACGATTTCAGCCTGGCTTGTGGTGGTGCTTAA
TCGATCGCTGGAGCGTCCCG

Downstream 100 bases:

>100_bases
GTTTACAACGGGTTACGCTGGAAAGCGCGCGTTATCGCTGGTATGGCGCGAGACGCTGGTCGCCGTTATTACAGAATGTC
TCTTTTGATATCGCGCCCGG

Product: inner membrane transport protein

Products: Ni2; [Cytoplasm]; ADP; phosphate [C]

Alternate protein names: NA

Number of amino acids: Translated: 270; Mature: 270

Protein sequence:

>270_residues
MLYNPAPTLFRLLLSVTCLLFIAGYGYATLSQPPEVNLLARHLSPDIQHWFGTDNLGRDVWLRCFQGAFTSLQIGVGAAL
CSGVIALVMAAVARIHPRLDLLVRLITDAMLAMPHLLLLILICFTLGGGKSGVIAAVALTHWPRLALILRADAERVAQSD
YLTLTYRLGHGHLYCWRYHYFPALLPQWLTGTLLMFPHAVLHSAALSFLGFGLAPHEPSLGLLLADALRFISHGNWWLVL
FPGLMLFTLVMLFDQFARAIQRLWLRSDVC

Sequences:

>Translated_270_residues
MLYNPAPTLFRLLLSVTCLLFIAGYGYATLSQPPEVNLLARHLSPDIQHWFGTDNLGRDVWLRCFQGAFTSLQIGVGAAL
CSGVIALVMAAVARIHPRLDLLVRLITDAMLAMPHLLLLILICFTLGGGKSGVIAAVALTHWPRLALILRADAERVAQSD
YLTLTYRLGHGHLYCWRYHYFPALLPQWLTGTLLMFPHAVLHSAALSFLGFGLAPHEPSLGLLLADALRFISHGNWWLVL
FPGLMLFTLVMLFDQFARAIQRLWLRSDVC
>Mature_270_residues
MLYNPAPTLFRLLLSVTCLLFIAGYGYATLSQPPEVNLLARHLSPDIQHWFGTDNLGRDVWLRCFQGAFTSLQIGVGAAL
CSGVIALVMAAVARIHPRLDLLVRLITDAMLAMPHLLLLILICFTLGGGKSGVIAAVALTHWPRLALILRADAERVAQSD
YLTLTYRLGHGHLYCWRYHYFPALLPQWLTGTLLMFPHAVLHSAALSFLGFGLAPHEPSLGLLLADALRFISHGNWWLVL
FPGLMLFTLVMLFDQFARAIQRLWLRSDVC

Specific function: Probably part of an ABC transporter complex that could be involved in peptide import. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG1173

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1789889, Length=235, Percent_Identity=30.2127659574468, Blast_Score=102, Evalue=3e-23,
Organism=Escherichia coli, GI1787054, Length=214, Percent_Identity=29.9065420560748, Blast_Score=96, Evalue=4e-21,
Organism=Escherichia coli, GI1787760, Length=233, Percent_Identity=27.0386266094421, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1789964, Length=210, Percent_Identity=33.8095238095238, Blast_Score=77, Evalue=9e-16,
Organism=Escherichia coli, GI1788505, Length=185, Percent_Identity=30.8108108108108, Blast_Score=68, Evalue=7e-13,
Organism=Escherichia coli, GI1787549, Length=218, Percent_Identity=27.0642201834862, Blast_Score=67, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 30067; Mature: 30067

Theoretical pI: Translated: 8.60; Mature: 8.60

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLYNPAPTLFRLLLSVTCLLFIAGYGYATLSQPPEVNLLARHLSPDIQHWFGTDNLGRDV
CCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHCCHHHHHHCCCCCCCHHH
WLRCFQGAFTSLQIGVGAALCSGVIALVMAAVARIHPRLDLLVRLITDAMLAMPHLLLLI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHH
LICFTLGGGKSGVIAAVALTHWPRLALILRADAERVAQSDYLTLTYRLGHGHLYCWRYHY
HHHHHCCCCCCHHHHHHHHHHCHHHHHHHHHHHHHHHCCCEEEEEEEECCCEEEEEEHHH
FPALLPQWLTGTLLMFPHAVLHSAALSFLGFGLAPHEPSLGLLLADALRFISHGNWWLVL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCEEEHH
FPGLMLFTLVMLFDQFARAIQRLWLRSDVC
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MLYNPAPTLFRLLLSVTCLLFIAGYGYATLSQPPEVNLLARHLSPDIQHWFGTDNLGRDV
CCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHCCHHHHHHCCCCCCCHHH
WLRCFQGAFTSLQIGVGAALCSGVIALVMAAVARIHPRLDLLVRLITDAMLAMPHLLLLI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHH
LICFTLGGGKSGVIAAVALTHWPRLALILRADAERVAQSDYLTLTYRLGHGHLYCWRYHY
HHHHHCCCCCCHHHHHHHHHHCHHHHHHHHHHHHHHHCCCEEEEEEEECCCEEEEEEHHH
FPALLPQWLTGTLLMFPHAVLHSAALSFLGFGLAPHEPSLGLLLADALRFISHGNWWLVL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCEEEHH
FPGLMLFTLVMLFDQFARAIQRLWLRSDVC
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Ni2; [Periplasm]; ATP; H2O [C]

Specific reaction: Ni2+ [Periplasm] + ATP + H2O = Ni2+ [Cytoplasm] + ADP + phosphate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA