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The map label for this gene is nikD [H]

Identifier: 29141606

GI number: 29141606

Start: 1209694

End: 1210491

Strand: Direct

Name: nikD [H]

Synonym: t1136

Alternate gene names: 29141606

Gene position: 1209694-1210491 (Clockwise)

Preceding gene: 29141605

Following gene: 29141607

Centisome position: 25.24

GC content: 55.01

Gene sequence:

>798_bases
ATGCTGAGTTTACAACGGGTTACGCTGGAAAGCGCGCGTTATCGCTGGTATGGCGCGAGACGCTGGTCGCCGTTATTACA
GAATGTCTCTTTTGATATCGCGCCCGGCGAAATGGTGGCATTGGTTGGCGGCAGCGGGGAGGGAAAAAGTCTGCTGCTGC
AATGCCTGCTCGATCTGCTGCCGGAAAACTTACGTTTTCGGGGTGAGATTACGCTTGATGGCAACCGGCTGGACAGACAT
ACCATCAGGCAGCTTAGGGGCAATACGTTTAGCTACGTGCCGCAGGGGGTACAGGCGCTTAATCCTATGCTGAATATCAG
AAAACATTTGAACAGAGCATGTCATCTGACCGGACGCGCCTGGGATGAGACGCAGATGGTACAGTTATTACAGCAAAGCG
ATCTTGCACCGACAGTCCTGGAACGCTTTCCCCGCCAGCTCTCCGGTGGGATGGCTAAACGAATTCTGGCGTGCCACGCC
TCGCTCAGCCAGGCACGTTATATCCTCGCGGATGAGATCACCGCCTGGCTTGATACGGCACTGGCAAACCAGTTGCTTGA
GCACTTGCGAGGTCTCTGCGAGCGGGGATGCGGCGTGCTGTGGGTGACTCATGACCTGCTGCTGGCGGCGCGGTATGCCG
ATCGCATTGTGGCGCTGCATCAGGGTTATATCACGGACAATATTCGCTGTGAACGATTACAGCCGGAAGAGATGAGTGAG
CCGTTAAAACGGCAATGGCAGGCATTGCCTGAACTAAACCCGTTATTTATGCCGACCGGAGAGGGAATAGAATGCTGA

Upstream 100 bases:

>100_bases
GGTGGCTGGTGCTATTTCCCGGCCTAATGTTATTCACGCTGGTGATGCTCTTCGATCAGTTTGCGCGCGCCATTCAGCGG
CTGTGGCTAAGGAGTGACGT

Downstream 100 bases:

>100_bases
GCTGCCGCGACCTCGTTATTCGTCAGGGCGGGAAAGTCTTATGGCAGAACCTGACGTTTACGATTTCTGCCGGTGAACGG
GTAGGAATTCATGCGCCAAG

Product: ABC transport ATP-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 265; Mature: 265

Protein sequence:

>265_residues
MLSLQRVTLESARYRWYGARRWSPLLQNVSFDIAPGEMVALVGGSGEGKSLLLQCLLDLLPENLRFRGEITLDGNRLDRH
TIRQLRGNTFSYVPQGVQALNPMLNIRKHLNRACHLTGRAWDETQMVQLLQQSDLAPTVLERFPRQLSGGMAKRILACHA
SLSQARYILADEITAWLDTALANQLLEHLRGLCERGCGVLWVTHDLLLAARYADRIVALHQGYITDNIRCERLQPEEMSE
PLKRQWQALPELNPLFMPTGEGIEC

Sequences:

>Translated_265_residues
MLSLQRVTLESARYRWYGARRWSPLLQNVSFDIAPGEMVALVGGSGEGKSLLLQCLLDLLPENLRFRGEITLDGNRLDRH
TIRQLRGNTFSYVPQGVQALNPMLNIRKHLNRACHLTGRAWDETQMVQLLQQSDLAPTVLERFPRQLSGGMAKRILACHA
SLSQARYILADEITAWLDTALANQLLEHLRGLCERGCGVLWVTHDLLLAARYADRIVALHQGYITDNIRCERLQPEEMSE
PLKRQWQALPELNPLFMPTGEGIEC
>Mature_265_residues
MLSLQRVTLESARYRWYGARRWSPLLQNVSFDIAPGEMVALVGGSGEGKSLLLQCLLDLLPENLRFRGEITLDGNRLDRH
TIRQLRGNTFSYVPQGVQALNPMLNIRKHLNRACHLTGRAWDETQMVQLLQQSDLAPTVLERFPRQLSGGMAKRILACHA
SLSQARYILADEITAWLDTALANQLLEHLRGLCERGCGVLWVTHDLLLAARYADRIVALHQGYITDNIRCERLQPEEMSE
PLKRQWQALPELNPLFMPTGEGIEC

Specific function: Part of the ABC transporter complex NikABCDE involved in nickel import. Responsible for energy coupling to the transport system [H]

COG id: COG1123

COG function: function code R; ATPase components of various ABC-type transport systems, contain duplicated ATPase

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Homo sapiens, GI90421313, Length=165, Percent_Identity=32.1212121212121, Blast_Score=68, Evalue=7e-12,
Organism=Homo sapiens, GI9955963, Length=241, Percent_Identity=28.2157676348548, Blast_Score=65, Evalue=6e-11,
Organism=Escherichia coli, GI1789890, Length=223, Percent_Identity=31.8385650224215, Blast_Score=111, Evalue=6e-26,
Organism=Escherichia coli, GI145693107, Length=225, Percent_Identity=29.7777777777778, Blast_Score=99, Evalue=2e-22,
Organism=Escherichia coli, GI1788506, Length=213, Percent_Identity=32.3943661971831, Blast_Score=92, Evalue=5e-20,
Organism=Escherichia coli, GI1787759, Length=218, Percent_Identity=30.7339449541284, Blast_Score=88, Evalue=7e-19,
Organism=Escherichia coli, GI1789672, Length=228, Percent_Identity=28.0701754385965, Blast_Score=87, Evalue=8e-19,
Organism=Escherichia coli, GI1789891, Length=219, Percent_Identity=30.5936073059361, Blast_Score=87, Evalue=8e-19,
Organism=Escherichia coli, GI1787105, Length=252, Percent_Identity=31.3492063492063, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI48994883, Length=209, Percent_Identity=28.2296650717703, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI1787029, Length=221, Percent_Identity=29.4117647058824, Blast_Score=84, Evalue=8e-18,
Organism=Escherichia coli, GI1787089, Length=220, Percent_Identity=31.3636363636364, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1789963, Length=232, Percent_Identity=28.8793103448276, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1788225, Length=232, Percent_Identity=30.1724137931034, Blast_Score=79, Evalue=2e-16,
Organism=Escherichia coli, GI48994997, Length=219, Percent_Identity=27.3972602739726, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1790544, Length=214, Percent_Identity=31.7757009345794, Blast_Score=74, Evalue=9e-15,
Organism=Escherichia coli, GI1786872, Length=235, Percent_Identity=28.5106382978723, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1788761, Length=210, Percent_Identity=30.4761904761905, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1789991, Length=239, Percent_Identity=22.1757322175732, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI1787370, Length=197, Percent_Identity=29.9492385786802, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI1786703, Length=208, Percent_Identity=33.1730769230769, Blast_Score=71, Evalue=7e-14,
Organism=Escherichia coli, GI1787547, Length=225, Percent_Identity=24.8888888888889, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1790467, Length=208, Percent_Identity=30.2884615384615, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI1787548, Length=249, Percent_Identity=24.4979919678715, Blast_Score=68, Evalue=6e-13,
Organism=Escherichia coli, GI1787792, Length=218, Percent_Identity=28.4403669724771, Blast_Score=65, Evalue=3e-12,
Organism=Escherichia coli, GI48995001, Length=240, Percent_Identity=28.3333333333333, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI1787758, Length=232, Percent_Identity=25.8620689655172, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI1790739, Length=254, Percent_Identity=27.9527559055118, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI87081709, Length=203, Percent_Identity=27.0935960591133, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1787500, Length=225, Percent_Identity=23.1111111111111, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1789962, Length=250, Percent_Identity=24.8, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1786345, Length=223, Percent_Identity=30.0448430493274, Blast_Score=62, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI71992285, Length=209, Percent_Identity=30.622009569378, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI212646699, Length=220, Percent_Identity=28.1818181818182, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17552010, Length=199, Percent_Identity=30.1507537688442, Blast_Score=65, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6323959, Length=235, Percent_Identity=27.6595744680851, Blast_Score=72, Evalue=1e-13,
Organism=Drosophila melanogaster, GI17647219, Length=176, Percent_Identity=28.9772727272727, Blast_Score=65, Evalue=3e-11,
Organism=Drosophila melanogaster, GI45552805, Length=194, Percent_Identity=27.8350515463918, Blast_Score=65, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR015857
- InterPro:   IPR003593
- InterPro:   IPR014138 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: =3.6.3.24 [H]

Molecular weight: Translated: 30076; Mature: 30076

Theoretical pI: Translated: 7.80; Mature: 7.80

Prosite motif: PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSLQRVTLESARYRWYGARRWSPLLQNVSFDIAPGEMVALVGGSGEGKSLLLQCLLDLL
CCCCHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHC
PENLRFRGEITLDGNRLDRHTIRQLRGNTFSYVPQGVQALNPMLNIRKHLNRACHLTGRA
CCCCEEEEEEEECCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
WDETQMVQLLQQSDLAPTVLERFPRQLSGGMAKRILACHASLSQARYILADEITAWLDTA
CCHHHHHHHHHHCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LANQLLEHLRGLCERGCGVLWVTHDLLLAARYADRIVALHQGYITDNIRCERLQPEEMSE
HHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHCCCCCCCCEECCCCHHHHHH
PLKRQWQALPELNPLFMPTGEGIEC
HHHHHHHHCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MLSLQRVTLESARYRWYGARRWSPLLQNVSFDIAPGEMVALVGGSGEGKSLLLQCLLDLL
CCCCHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHC
PENLRFRGEITLDGNRLDRHTIRQLRGNTFSYVPQGVQALNPMLNIRKHLNRACHLTGRA
CCCCEEEEEEEECCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
WDETQMVQLLQQSDLAPTVLERFPRQLSGGMAKRILACHASLSQARYILADEITAWLDTA
CCHHHHHHHHHHCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LANQLLEHLRGLCERGCGVLWVTHDLLLAARYADRIVALHQGYITDNIRCERLQPEEMSE
HHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHCCCCCCCCEECCCCHHHHHH
PLKRQWQALPELNPLFMPTGEGIEC
HHHHHHHHCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]