Click here to switch to the map view.

The map label for this gene is dppB [C]

Identifier: 29141604

GI number: 29141604

Start: 1207921

End: 1208898

Strand: Direct

Name: dppB [C]

Synonym: t1135

Alternate gene names: 29141604

Gene position: 1207921-1208898 (Clockwise)

Preceding gene: 29141603

Following gene: 29141605

Centisome position: 25.21

GC content: 53.27

Gene sequence:

>978_bases
GTGATGAAATTGTTCTTCAGTCATTTTTTGCGGCTGATTATTCTGTTGGTGCTGGTGGCTGCCGGCACCTTCATTTTGCT
TAGCTTTTCGCCCGTTGATCCTATCCGTGCTTATATTGGCAACGATCTGCTCCATGTTCCGCCAGAACAATATGCGCGGA
TTGCGGCGCGCTGGGGGCTTGACCAGCCGCTGTGGGAGCGTTTCGGTCACTGGTTTTGGCGTCTGCTCCAGGGCGACATG
GGGTATTCCATGCTGTTCAACATGCCTGTCGCCAGCGTGATCCGGGAACGTTTTGCGACGTCATTCGCGCTGCTGGCAGG
CGCCTGGCTATTGTCTGGTGTGCTGGGCGTAACATTGGGTTTTCTGGCCGGACGTTTTCTCCACCGTTGGCCGGATAAGA
TGATTTGCCGTATCAGCTACTTATTGTCATCGTTGCCCACTTTCTGGATAGCAATGCTGTTGCTGGCGCTGTTTGCCGTC
CGCTGGCCGGTATTACCTGTTTGTTGCGCCTGGGACCCCGGAAATAATGCAGGAACAGCTCTTTTATCGGAACGTTTACG
CCATCTTGTGTTGCCGGTATGTGCGTTAAGTCTGTTGGGCATGGGGCAAATTGCGCTGCATACGCGAGAAAAAATAGCCA
GCGTAATGAAGAGCGAATTTATTCGTTTTGCGCGCGCTCAGGGGGATAAAGGATGGTCGCTGTTACGTCACCAGGTGTTA
CGTCATGCGATTACCCCAGCGCTCTGCTTACAGTTTGCTTCTCTGGGTGAACTGATGGGGGGAGCGTTACTGGCAGAAAA
AGTCTTTGCGTATCCGGGGCTGGGACAGGCCACTATCGATGCCGGCCTGCGTGGCGATGTCCCGCTACTCATGGGGATCG
TTTTATTCTGTACGCTATTAGTGTTTGCCGGAAATACGATTTCAGCCTGGCTTGTGGTGGTGCTTAATCGATCGCTGGAG
CGTCCCGATGCTCTATAA

Upstream 100 bases:

>100_bases
ATCTGGCCAACCCCTGTATTGATCTGGGAAAAGGCTCGCCAGAAATCCACGGTAGCTGGTCGGTGTTAAACAATCTTGAT
GACTGGACCTGGACCTGTCG

Downstream 100 bases:

>100_bases
TCCTGCCCCGACGTTGTTTCGTCTGCTCCTCTCCGTTACCTGTCTGCTGTTTATTGCCGGATACGGTTATGCCACGTTGA
GCCAGCCGCCAGAGGTTAAT

Product: inner membrane transport protein

Products: ADP; phosphate; dipeptides [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 325; Mature: 325

Protein sequence:

>325_residues
MMKLFFSHFLRLIILLVLVAAGTFILLSFSPVDPIRAYIGNDLLHVPPEQYARIAARWGLDQPLWERFGHWFWRLLQGDM
GYSMLFNMPVASVIRERFATSFALLAGAWLLSGVLGVTLGFLAGRFLHRWPDKMICRISYLLSSLPTFWIAMLLLALFAV
RWPVLPVCCAWDPGNNAGTALLSERLRHLVLPVCALSLLGMGQIALHTREKIASVMKSEFIRFARAQGDKGWSLLRHQVL
RHAITPALCLQFASLGELMGGALLAEKVFAYPGLGQATIDAGLRGDVPLLMGIVLFCTLLVFAGNTISAWLVVVLNRSLE
RPDAL

Sequences:

>Translated_325_residues
MMKLFFSHFLRLIILLVLVAAGTFILLSFSPVDPIRAYIGNDLLHVPPEQYARIAARWGLDQPLWERFGHWFWRLLQGDM
GYSMLFNMPVASVIRERFATSFALLAGAWLLSGVLGVTLGFLAGRFLHRWPDKMICRISYLLSSLPTFWIAMLLLALFAV
RWPVLPVCCAWDPGNNAGTALLSERLRHLVLPVCALSLLGMGQIALHTREKIASVMKSEFIRFARAQGDKGWSLLRHQVL
RHAITPALCLQFASLGELMGGALLAEKVFAYPGLGQATIDAGLRGDVPLLMGIVLFCTLLVFAGNTISAWLVVVLNRSLE
RPDAL
>Mature_325_residues
MMKLFFSHFLRLIILLVLVAAGTFILLSFSPVDPIRAYIGNDLLHVPPEQYARIAARWGLDQPLWERFGHWFWRLLQGDM
GYSMLFNMPVASVIRERFATSFALLAGAWLLSGVLGVTLGFLAGRFLHRWPDKMICRISYLLSSLPTFWIAMLLLALFAV
RWPVLPVCCAWDPGNNAGTALLSERLRHLVLPVCALSLLGMGQIALHTREKIASVMKSEFIRFARAQGDKGWSLLRHQVL
RHAITPALCLQFASLGELMGGALLAEKVFAYPGLGQATIDAGLRGDVPLLMGIVLFCTLLVFAGNTISAWLVVVLNRSLE
RPDAL

Specific function: Probably part of an ABC transporter complex that could be involved in peptide import. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG0601

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1789965, Length=312, Percent_Identity=29.1666666666667, Blast_Score=135, Evalue=4e-33,
Organism=Escherichia coli, GI1787053, Length=325, Percent_Identity=29.2307692307692, Blast_Score=134, Evalue=6e-33,
Organism=Escherichia coli, GI1789888, Length=323, Percent_Identity=27.2445820433437, Blast_Score=124, Evalue=1e-29,
Organism=Escherichia coli, GI1787761, Length=308, Percent_Identity=31.4935064935065, Blast_Score=119, Evalue=4e-28,
Organism=Escherichia coli, GI1787497, Length=327, Percent_Identity=27.82874617737, Blast_Score=114, Evalue=8e-27,
Organism=Escherichia coli, GI1787550, Length=266, Percent_Identity=28.5714285714286, Blast_Score=105, Evalue=4e-24,
Organism=Escherichia coli, GI1788504, Length=276, Percent_Identity=26.4492753623188, Blast_Score=80, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 36140; Mature: 36140

Theoretical pI: Translated: 9.82; Mature: 9.82

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMKLFFSHFLRLIILLVLVAAGTFILLSFSPVDPIRAYIGNDLLHVPPEQYARIAARWGL
CHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCHHHHHHHCCCCEECCHHHHHHHHHHCCC
DQPLWERFGHWFWRLLQGDMGYSMLFNMPVASVIRERFATSFALLAGAWLLSGVLGVTLG
CHHHHHHHHHHHHHHHHCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FLAGRFLHRWPDKMICRISYLLSSLPTFWIAMLLLALFAVRWPVLPVCCAWDPGNNAGTA
HHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHEEECCCCCCCHHHH
LLSERLRHLVLPVCALSLLGMGQIALHTREKIASVMKSEFIRFARAQGDKGWSLLRHQVL
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
RHAITPALCLQFASLGELMGGALLAEKVFAYPGLGQATIDAGLRGDVPLLMGIVLFCTLL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCCCCHHHHHHHHHHHHHH
VFAGNTISAWLVVVLNRSLERPDAL
HHHCCHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MMKLFFSHFLRLIILLVLVAAGTFILLSFSPVDPIRAYIGNDLLHVPPEQYARIAARWGL
CHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCHHHHHHHCCCCEECCHHHHHHHHHHCCC
DQPLWERFGHWFWRLLQGDMGYSMLFNMPVASVIRERFATSFALLAGAWLLSGVLGVTLG
CHHHHHHHHHHHHHHHHCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FLAGRFLHRWPDKMICRISYLLSSLPTFWIAMLLLALFAVRWPVLPVCCAWDPGNNAGTA
HHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHEEECCCCCCCHHHH
LLSERLRHLVLPVCALSLLGMGQIALHTREKIASVMKSEFIRFARAQGDKGWSLLRHQVL
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
RHAITPALCLQFASLGELMGGALLAEKVFAYPGLGQATIDAGLRGDVPLLMGIVLFCTLL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCCCCHHHHHHHHHHHHHH
VFAGNTISAWLVVVLNRSLERPDAL
HHHCCHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; dipeptides [Periplasm]; H2O [C]

Specific reaction: ATP + dipeptides [Periplasm] + H2O = ADP + phosphate + dipeptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11756688 [H]