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The map label for this gene is cbiT

Identifier: 29141340

GI number: 29141340

Start: 938105

End: 938683

Strand: Direct

Name: cbiT

Synonym: t0844

Alternate gene names: 29141340

Gene position: 938105-938683 (Clockwise)

Preceding gene: 29141339

Following gene: 29141341

Centisome position: 19.58

GC content: 56.13

Gene sequence:

>579_bases
ATGAAAGATGAGCTTTTTCTGCGCGGCGAGAACGTGCCAATGACCAAAGAGGCGGTACGGGCGCTGGCACTGTCGAAACT
TGAGCTCCACCGCGCCAGTCACCTGATTGACGTCGGGGCGGGAACGGGAAGCGTCTCAATTGAAGCGGCGCTGCAATTTC
CTTCGTTGCAGGTGACGGCTATTGAGCGTAATCCTGCCGCGCTACGGCTGCTTGATGAGAATCGTCAGCGCTTTGCCTGC
GGCAATATCGATATTCTCCCCGGCGAAGCGCCAATGACCATAACCGGGAAAGCCGATGCGGTGTTTATGGGCGGCAGCGG
CGGGCATCTGACGGCGCTGATTGACTGGGCGATGGGCCATCTGCATCCCGGTGGCCGTCTGGTGATGACCTTTATCTTGC
AGGAAAACCTCCATAGCGCGCTGGCGCATCTTGTGCACATCGGCGCATGCCGAATGGACTGTGTACAGCTTCAGCTTTCA
TCGTTAACGCCGCTGGGGGCGGGACACTATTTCAAACCGAACAACCCTGTTTTTGTTATAGCCTGTCAGAAGGAAGAAAA
CCATGTCAGAGACATTTGA

Upstream 100 bases:

>100_bases
GTGATTGGTGAAAATCTGGCGATGGAAAATGAGCGGATCCACTGGCTACCCGTCAGTGCGGTCAACGCCGACTATGAAAT
GAATGCAGTGGTGATCCTGG

Downstream 100 bases:

>100_bases
TCCACGCTGTGTATGGTTCGTCGGCGCCGGGCCGGGCGATCGCGAGCTGATCACGCTTAAAGGCTACCGCCTGCTGCAAC
AGGCGCAGGTAGTTATCTAT

Product: cobalt-precorrin-6Y C(15)-methyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 192; Mature: 192

Protein sequence:

>192_residues
MKDELFLRGENVPMTKEAVRALALSKLELHRASHLIDVGAGTGSVSIEAALQFPSLQVTAIERNPAALRLLDENRQRFAC
GNIDILPGEAPMTITGKADAVFMGGSGGHLTALIDWAMGHLHPGGRLVMTFILQENLHSALAHLVHIGACRMDCVQLQLS
SLTPLGAGHYFKPNNPVFVIACQKEENHVRDI

Sequences:

>Translated_192_residues
MKDELFLRGENVPMTKEAVRALALSKLELHRASHLIDVGAGTGSVSIEAALQFPSLQVTAIERNPAALRLLDENRQRFAC
GNIDILPGEAPMTITGKADAVFMGGSGGHLTALIDWAMGHLHPGGRLVMTFILQENLHSALAHLVHIGACRMDCVQLQLS
SLTPLGAGHYFKPNNPVFVIACQKEENHVRDI
>Mature_192_residues
MKDELFLRGENVPMTKEAVRALALSKLELHRASHLIDVGAGTGSVSIEAALQFPSLQVTAIERNPAALRLLDENRQRFAC
GNIDILPGEAPMTITGKADAVFMGGSGGHLTALIDWAMGHLHPGGRLVMTFILQENLHSALAHLVHIGACRMDCVQLQLS
SLTPLGAGHYFKPNNPVFVIACQKEENHVRDI

Specific function: Probably catalyzes the methylation of either C-15 or C-5 in cobalt-precorrin-6Y to form cobalt-precorrin-7W. Methylation of C-15 would probably be followed by a spontaneous decarboxylation of C-12

COG id: COG2242

COG function: function code H; Precorrin-6B methylase 2

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. Bacterial-type CbiT family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CBIT_SALTI (Q8Z5M9)

Other databases:

- EMBL:   AL627273
- EMBL:   AE014613
- RefSeq:   NP_456581.1
- RefSeq:   NP_804682.1
- ProteinModelPortal:   Q8Z5M9
- SMR:   Q8Z5M9
- GeneID:   1070123
- GeneID:   1248573
- GenomeReviews:   AE014613_GR
- GenomeReviews:   AL513382_GR
- KEGG:   stt:t0844
- KEGG:   sty:STY2235
- HOGENOM:   HBG553505
- OMA:   RNIEVVQ
- ProtClustDB:   PRK08287
- BioCyc:   SENT209261:T0844-MONOMER
- BioCyc:   SENT220341:STY2235-MONOMER
- InterPro:   IPR014008
- InterPro:   IPR007848
- TIGRFAMs:   TIGR02469

Pfam domain/function: PF05175 MTS

EC number: 1.-.-.-

Molecular weight: Translated: 20774; Mature: 20774

Theoretical pI: Translated: 6.85; Mature: 6.85

Prosite motif: NA

Important sites: BINDING 15-15 BINDING 62-62 BINDING 90-90

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKDELFLRGENVPMTKEAVRALALSKLELHRASHLIDVGAGTGSVSIEAALQFPSLQVTA
CCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHCEEEECCCCCCEEEEEEEECCCEEEEE
IERNPAALRLLDENRQRFACGNIDILPGEAPMTITGKADAVFMGGSGGHLTALIDWAMGH
EECCCEEEEEEECCCCEEECCCEEEECCCCCEEEECCCCEEEECCCCCEEEEEEEHHHHC
LHPGGRLVMTFILQENLHSALAHLVHIGACRMDCVQLQLSSLTPLGAGHYFKPNNPVFVI
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEE
ACQKEENHVRDI
EEECCCCCCCCC
>Mature Secondary Structure
MKDELFLRGENVPMTKEAVRALALSKLELHRASHLIDVGAGTGSVSIEAALQFPSLQVTA
CCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHCEEEECCCCCCEEEEEEEECCCEEEEE
IERNPAALRLLDENRQRFACGNIDILPGEAPMTITGKADAVFMGGSGGHLTALIDWAMGH
EECCCEEEEEEECCCCEEECCCEEEECCCCCEEEECCCCEEEECCCCCEEEEEEEHHHHC
LHPGGRLVMTFILQENLHSALAHLVHIGACRMDCVQLQLSSLTPLGAGHYFKPNNPVFVI
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEE
ACQKEENHVRDI
EEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11677608; 12644504