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The map label for this gene is trxB1 [H]

Identifier: 28377619

GI number: 28377619

Start: 695482

End: 696420

Strand: Direct

Name: trxB1 [H]

Synonym: lp_0761

Alternate gene names: 28377619

Gene position: 695482-696420 (Clockwise)

Preceding gene: 28377618

Following gene: 28377622

Centisome position: 21.02

GC content: 46.54

Gene sequence:

>939_bases
ATGGCAAAGAGTTACGACGTGATTATTATTGGTGCGGGGCCTGCCGGCATGACAGCCGCCCTCTATGCTTCACGAGCCAA
TCTATCAGTGCTACTATTAGATCGCGGAATCTATGGTGGGCAAATGAATAATACCGCCGCAATTGAAAATTATCCGGGCT
TCAAATCTGTTTTGGGGCCGGATTTGGCTAAAGACATGTATGAATCAGCGACCCAGTTTGGTGCTGAATACGCGTATGGT
AGCGTCGAATCCGTTGAAGATCGCGGCGATGTTAAAATCGTGACGACGGATAGCGATACGTTTGAGACTAAGGCCCTTGT
CATTGGGACTGGTTCTGAATATCGTAAGCTGGGTGTTACTGGCGAGGATACGTATGGTGGCCGCGGTGTCTCATACTGCG
CAGTTTGTGATGGAGCGTTTTTCCGTAACAAGCATGTAGTTGTCGTTGGTGGCGGTGACTCAGCGATTGAGGAAGGCACT
TACCTGACACAGCTTGCTGATAAGGTGACGGTTATTCATCGTCGTGACCAATTGCGGGCACAACAAATCTTACAAGATCG
GGCTTTTGCTAATCCAAAGATGGAATTTGTTTGGAATAGCAACGTGACGGAAATCATCGGTGATGATAAGAAGGTCACGG
GAGTTAAGGTTAATAATAATAAGACTGGTGAAGACAGTGAGATTGCGGTCGATGGTGTCTTTATCTATGTTGGTATTAAC
CCAATTACGAAGCCATTCAGTAATCTTGGGATTACTGACGAAAACGGCTGGATCGAAACTAATGACCACATGGAAACCAA
GGTCCCTGGTATTTTTGCAGTCGGTGATGTTCGTAAGAAAGATTTACGCCAAGTTGCGACGGCGGTTGGTGAAGGCGGAA
CTGCCGGTCAAGGCGTTTACACTTATATCACTGCTTTAGGCGACAAAGTTAACAATTAA

Upstream 100 bases:

>100_bases
ATAATTGACTTCAGTTGTGTACAAACAAGATAGTCGACAAATGTAAATTTTGGGGGTATATTAAGCGTCATAGGAATTTA
AGTGGAAGGGGTCTTTAGAA

Downstream 100 bases:

>100_bases
ATAAAATTAAAAAATGCGTAGCTGATTTAATTGAGATCAGCCACGCATTTTTTATTGGTAAATATAGCGTTAGTCATTGT
TTGACGATGACCAAAGGTTC

Product: thioredoxin reductase (NADPH)

Products: NA

Alternate protein names: TRXR [H]

Number of amino acids: Translated: 312; Mature: 311

Protein sequence:

>312_residues
MAKSYDVIIIGAGPAGMTAALYASRANLSVLLLDRGIYGGQMNNTAAIENYPGFKSVLGPDLAKDMYESATQFGAEYAYG
SVESVEDRGDVKIVTTDSDTFETKALVIGTGSEYRKLGVTGEDTYGGRGVSYCAVCDGAFFRNKHVVVVGGGDSAIEEGT
YLTQLADKVTVIHRRDQLRAQQILQDRAFANPKMEFVWNSNVTEIIGDDKKVTGVKVNNNKTGEDSEIAVDGVFIYVGIN
PITKPFSNLGITDENGWIETNDHMETKVPGIFAVGDVRKKDLRQVATAVGEGGTAGQGVYTYITALGDKVNN

Sequences:

>Translated_312_residues
MAKSYDVIIIGAGPAGMTAALYASRANLSVLLLDRGIYGGQMNNTAAIENYPGFKSVLGPDLAKDMYESATQFGAEYAYG
SVESVEDRGDVKIVTTDSDTFETKALVIGTGSEYRKLGVTGEDTYGGRGVSYCAVCDGAFFRNKHVVVVGGGDSAIEEGT
YLTQLADKVTVIHRRDQLRAQQILQDRAFANPKMEFVWNSNVTEIIGDDKKVTGVKVNNNKTGEDSEIAVDGVFIYVGIN
PITKPFSNLGITDENGWIETNDHMETKVPGIFAVGDVRKKDLRQVATAVGEGGTAGQGVYTYITALGDKVNN
>Mature_311_residues
AKSYDVIIIGAGPAGMTAALYASRANLSVLLLDRGIYGGQMNNTAAIENYPGFKSVLGPDLAKDMYESATQFGAEYAYGS
VESVEDRGDVKIVTTDSDTFETKALVIGTGSEYRKLGVTGEDTYGGRGVSYCAVCDGAFFRNKHVVVVGGGDSAIEEGTY
LTQLADKVTVIHRRDQLRAQQILQDRAFANPKMEFVWNSNVTEIIGDDKKVTGVKVNNNKTGEDSEIAVDGVFIYVGINP
ITKPFSNLGITDENGWIETNDHMETKVPGIFAVGDVRKKDLRQVATAVGEGGTAGQGVYTYITALGDKVNN

Specific function: Unknown

COG id: COG0492

COG function: function code O; Thioredoxin reductase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family [H]

Homologues:

Organism=Homo sapiens, GI21389617, Length=325, Percent_Identity=24.9230769230769, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI65787454, Length=325, Percent_Identity=24.9230769230769, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI226437568, Length=325, Percent_Identity=24.9230769230769, Blast_Score=73, Evalue=4e-13,
Organism=Escherichia coli, GI1787114, Length=316, Percent_Identity=37.6582278481013, Blast_Score=208, Evalue=5e-55,
Organism=Escherichia coli, GI87081763, Length=305, Percent_Identity=30.4918032786885, Blast_Score=150, Evalue=1e-37,
Organism=Saccharomyces cerevisiae, GI6320560, Length=313, Percent_Identity=39.9361022364217, Blast_Score=213, Evalue=2e-56,
Organism=Saccharomyces cerevisiae, GI6321898, Length=314, Percent_Identity=36.3057324840764, Blast_Score=192, Evalue=7e-50,

Paralogues:

None

Copy number: 808 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR008255
- InterPro:   IPR001327
- InterPro:   IPR000103
- InterPro:   IPR005982 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2 [H]

EC number: =1.8.1.9 [H]

Molecular weight: Translated: 33456; Mature: 33325

Theoretical pI: Translated: 4.61; Mature: 4.61

Prosite motif: PS00573 PYRIDINE_REDOX_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKSYDVIIIGAGPAGMTAALYASRANLSVLLLDRGIYGGQMNNTAAIENYPGFKSVLGP
CCCCEEEEEEECCCCCCCCEEEECCCCEEEEEEECCCCCCCCCCCEEECCCCCHHHHHCH
DLAKDMYESATQFGAEYAYGSVESVEDRGDVKIVTTDSDTFETKALVIGTGSEYRKLGVT
HHHHHHHHHHHHHCHHHCCCCHHCCCCCCCEEEEECCCCCCEEEEEEEECCCCCEEECCC
GEDTYGGRGVSYCAVCDGAFFRNKHVVVVGGGDSAIEEGTYLTQLADKVTVIHRRDQLRA
CCCCCCCCCEEEEEEECCCEECCCEEEEEECCCCHHHCCHHHHHHHHHHHEEHHHHHHHH
QQILQDRAFANPKMEFVWNSNVTEIIGDDKKVTGVKVNNNKTGEDSEIAVDGVFIYVGIN
HHHHHHHHCCCCCEEEEECCCCHHCCCCCCEEEEEEECCCCCCCCCEEEEEEEEEEEECC
PITKPFSNLGITDENGWIETNDHMETKVPGIFAVGDVRKKDLRQVATAVGEGGTAGQGVY
HHHCCHHHCCCCCCCCEEECCCCCCCCCCCEEEECCCCHHHHHHHHHHHCCCCCCCCCHH
TYITALGDKVNN
HHHHHHHHCCCC
>Mature Secondary Structure 
AKSYDVIIIGAGPAGMTAALYASRANLSVLLLDRGIYGGQMNNTAAIENYPGFKSVLGP
CCCEEEEEEECCCCCCCCEEEECCCCEEEEEEECCCCCCCCCCCEEECCCCCHHHHHCH
DLAKDMYESATQFGAEYAYGSVESVEDRGDVKIVTTDSDTFETKALVIGTGSEYRKLGVT
HHHHHHHHHHHHHCHHHCCCCHHCCCCCCCEEEEECCCCCCEEEEEEEECCCCCEEECCC
GEDTYGGRGVSYCAVCDGAFFRNKHVVVVGGGDSAIEEGTYLTQLADKVTVIHRRDQLRA
CCCCCCCCCEEEEEEECCCEECCCEEEEEECCCCHHHCCHHHHHHHHHHHEEHHHHHHHH
QQILQDRAFANPKMEFVWNSNVTEIIGDDKKVTGVKVNNNKTGEDSEIAVDGVFIYVGIN
HHHHHHHHCCCCCEEEEECCCCHHCCCCCCEEEEEEECCCCCCCCCEEEEEEEEEEEECC
PITKPFSNLGITDENGWIETNDHMETKVPGIFAVGDVRKKDLRQVATAVGEGGTAGQGVY
HHHCCHHHCCCCCCCCEEECCCCCCCCCCCEEEECCCCHHHHHHHHHHHCCCCCCCCCHH
TYITALGDKVNN
HHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11679669 [H]