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The map label for this gene is pgm [H]

Identifier: 28377622

GI number: 28377622

Start: 697830

End: 699557

Strand: Direct

Name: pgm [H]

Synonym: lp_0764

Alternate gene names: 28377622

Gene position: 697830-699557 (Clockwise)

Preceding gene: 28377619

Following gene: 28377624

Centisome position: 21.09

GC content: 44.33

Gene sequence:

>1728_bases
GTGAGTTGGCAGGATACTTATAATACCTGGAAAAACCAAGCGACACTTGAAACTAGTTTAAAACAAGAATTGACGGGCAT
GGCTGGCGATGACGCCGCCTTAGAAGACGCCTTTTATGAACCAATGGAATTCGGAACCGCGGGGATGCGGGGGGTACTTG
GACCTGGTATCAACCGGATGAATATTTATACGGTTCGTCAAGCAACGGAAGGGTTAGCACGCTTCATGGATACCTTGCCT
GCTGAGGTTAAGGAACGCGGGGTAGCAATCAGTTTTGATTCCCGCCATCATTCAGAAGATTTTGCGCATGAATCTGCGCG
AGTATTGGGCCAACATGGTATCAAGTCATACGTTTTTGAAAGCTTGCGGCCAACCCCAGAACTTTCATTTACCGTTCGGC
ATCTGCATACTTACGCAGGGATCATGATTACGGCGAGCCATAATCCGAAGCAATATAATGGCTACAAGATTTATGGCGAA
GATGGTGGTCAAATGCCACCTAAGGAATCTGATCTTATCACATCATATATTCGTAAAGTTGACGATGTCTTTGCGATTGC
CGTTGCTGATGAACAACAATTATTAGCTGATAAGACGGAAACCATTATTGGGGATGATGTCGATCAGGACTACTTAGCTA
AGGTCAAAGAAGTGACGATCAATCAAAAACTAGTGGATGAAGTCGGTAAGGACATGAAGTTAGTCTTCACACCATTACAT
GGGACTGGCCGGATGCTTGGCGAAAAGGCTTTGAAGAATGCCGGGTTTAAAAACTTCAGTGTTGTTAAGGAACAAGCTGT
GGCTGACCCTGAATTCTCGACGGTTAAATTCCCTAATCCTGAATTTCCTGAAGCCTTTAAGATGGCCATTGATTTGGGTA
AAAAAGAAGGTGCGGATGTCTTGATTGCGGTTGATCCTGATGCTGACCGGTTAGGGACAGCTGTTCGTCAACCTAATGGT
GAGTATGTTCTGTTGACGGGTAATCAAATTGCCGCTGTCTTGTTACACTACATCTTGCAAGCAAACAAGGATGCCGGGAC
GTTACCGACCAATGCGGCCGCAGTTAAGTCAATTGTTTCAAGTGAATTTGCTACTAAAGTAGCGGCTTCATATGGTGTCA
CGATGATCAATGTCTTGACCGGTTTCAAGTATATTGCTGAACAAATCGAACATTTTGAAGCCACTGGCGAACATACCTAT
ATGTTTGGTTTTGAAGAAAGTTACGGTTACTTAATCAAACCATTTGTTCATGACAAGGATGCGATTCAAACCACAGTGCT
TTTAGCCGAAGTAGCGGCTTATTATAAGCAACAAGGTAAGAACCTTTATGATGGATTACAAGACTTGTTTAAGGAATACG
GTTACTTCCGCGAGCAAACCACGTCCGAAGAATTTGATGGCGTTGGCGGCAGCGATAAGATTGCGGCTCTGATGACTAAG
TTCCGAAGCGAAGCACCAACTGCCTTTGCCGGCTACGATGTCACTGGGACTGAAGACTTCCAGAGTCAAACGGAAAGCTT
TGCTGATGGCCACACGGCACCAATTGCTTTGCCAAAGGCGAATGTCTTGAAGTATCATTTAAATGATGGCACTTGGATCG
CCATTCGGCCATCTGGTACGGAACCAAAGATCAAGTTCTACATTGGAACGCTAGGTAGTACGTTAGAAGAAGCTAATGAT
AAGTTAGCGAAATTTGAAGATGCCATTCAAGCGTTTATTAAAGAATAA

Upstream 100 bases:

>100_bases
ATTAATGGATTTTCTTAGTAAATTTTACTTTGTAAAGTGTGTCAATGTTGTATACTATTTTTGTAAGCACTAACAAATAT
CGGAATTGGAGATGGTTTTT

Downstream 100 bases:

>100_bases
ATTGGTTATTTAGTCAGAAGTTGTACGGCCCAGCTGACTAGCCATGCTAAGTGATAAATAACGCCTTACGAAATTTCAAG
TTAATTTCGTAAGGCGTTAT

Product: phosphoglucomutase

Products: NA

Alternate protein names: PGM; Alpha-phosphoglucomutase; Glucose phosphomutase [H]

Number of amino acids: Translated: 575; Mature: 574

Protein sequence:

>575_residues
MSWQDTYNTWKNQATLETSLKQELTGMAGDDAALEDAFYEPMEFGTAGMRGVLGPGINRMNIYTVRQATEGLARFMDTLP
AEVKERGVAISFDSRHHSEDFAHESARVLGQHGIKSYVFESLRPTPELSFTVRHLHTYAGIMITASHNPKQYNGYKIYGE
DGGQMPPKESDLITSYIRKVDDVFAIAVADEQQLLADKTETIIGDDVDQDYLAKVKEVTINQKLVDEVGKDMKLVFTPLH
GTGRMLGEKALKNAGFKNFSVVKEQAVADPEFSTVKFPNPEFPEAFKMAIDLGKKEGADVLIAVDPDADRLGTAVRQPNG
EYVLLTGNQIAAVLLHYILQANKDAGTLPTNAAAVKSIVSSEFATKVAASYGVTMINVLTGFKYIAEQIEHFEATGEHTY
MFGFEESYGYLIKPFVHDKDAIQTTVLLAEVAAYYKQQGKNLYDGLQDLFKEYGYFREQTTSEEFDGVGGSDKIAALMTK
FRSEAPTAFAGYDVTGTEDFQSQTESFADGHTAPIALPKANVLKYHLNDGTWIAIRPSGTEPKIKFYIGTLGSTLEEAND
KLAKFEDAIQAFIKE

Sequences:

>Translated_575_residues
MSWQDTYNTWKNQATLETSLKQELTGMAGDDAALEDAFYEPMEFGTAGMRGVLGPGINRMNIYTVRQATEGLARFMDTLP
AEVKERGVAISFDSRHHSEDFAHESARVLGQHGIKSYVFESLRPTPELSFTVRHLHTYAGIMITASHNPKQYNGYKIYGE
DGGQMPPKESDLITSYIRKVDDVFAIAVADEQQLLADKTETIIGDDVDQDYLAKVKEVTINQKLVDEVGKDMKLVFTPLH
GTGRMLGEKALKNAGFKNFSVVKEQAVADPEFSTVKFPNPEFPEAFKMAIDLGKKEGADVLIAVDPDADRLGTAVRQPNG
EYVLLTGNQIAAVLLHYILQANKDAGTLPTNAAAVKSIVSSEFATKVAASYGVTMINVLTGFKYIAEQIEHFEATGEHTY
MFGFEESYGYLIKPFVHDKDAIQTTVLLAEVAAYYKQQGKNLYDGLQDLFKEYGYFREQTTSEEFDGVGGSDKIAALMTK
FRSEAPTAFAGYDVTGTEDFQSQTESFADGHTAPIALPKANVLKYHLNDGTWIAIRPSGTEPKIKFYIGTLGSTLEEAND
KLAKFEDAIQAFIKE
>Mature_574_residues
SWQDTYNTWKNQATLETSLKQELTGMAGDDAALEDAFYEPMEFGTAGMRGVLGPGINRMNIYTVRQATEGLARFMDTLPA
EVKERGVAISFDSRHHSEDFAHESARVLGQHGIKSYVFESLRPTPELSFTVRHLHTYAGIMITASHNPKQYNGYKIYGED
GGQMPPKESDLITSYIRKVDDVFAIAVADEQQLLADKTETIIGDDVDQDYLAKVKEVTINQKLVDEVGKDMKLVFTPLHG
TGRMLGEKALKNAGFKNFSVVKEQAVADPEFSTVKFPNPEFPEAFKMAIDLGKKEGADVLIAVDPDADRLGTAVRQPNGE
YVLLTGNQIAAVLLHYILQANKDAGTLPTNAAAVKSIVSSEFATKVAASYGVTMINVLTGFKYIAEQIEHFEATGEHTYM
FGFEESYGYLIKPFVHDKDAIQTTVLLAEVAAYYKQQGKNLYDGLQDLFKEYGYFREQTTSEEFDGVGGSDKIAALMTKF
RSEAPTAFAGYDVTGTEDFQSQTESFADGHTAPIALPKANVLKYHLNDGTWIAIRPSGTEPKIKFYIGTLGSTLEEANDK
LAKFEDAIQAFIKE

Specific function: Catalyzes the interconversion between glucose-6- phosphate and alpha-glucose-1-phosphate. This is the first step in the biosynthesis of diglucosyl-diacylglycerol (Glc2-DAG), i.e. the predominant glycolipid found in B.subtilis membrane, which is also used

COG id: COG1109

COG function: function code G; Phosphomannomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphohexose mutase family [H]

Homologues:

Organism=Homo sapiens, GI63055049, Length=558, Percent_Identity=32.7956989247312, Blast_Score=283, Evalue=4e-76,
Organism=Homo sapiens, GI31377548, Length=545, Percent_Identity=30.4587155963303, Blast_Score=245, Evalue=8e-65,
Organism=Escherichia coli, GI1786904, Length=539, Percent_Identity=25.7884972170686, Blast_Score=84, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI71993870, Length=531, Percent_Identity=30.6967984934087, Blast_Score=220, Evalue=1e-57,
Organism=Caenorhabditis elegans, GI71993878, Length=281, Percent_Identity=33.8078291814947, Blast_Score=140, Evalue=2e-33,
Organism=Saccharomyces cerevisiae, GI6323934, Length=611, Percent_Identity=30.6055646481178, Blast_Score=206, Evalue=6e-54,
Organism=Drosophila melanogaster, GI20129809, Length=567, Percent_Identity=27.689594356261, Blast_Score=227, Evalue=2e-59,
Organism=Drosophila melanogaster, GI24651977, Length=436, Percent_Identity=30.045871559633, Blast_Score=210, Evalue=2e-54,
Organism=Drosophila melanogaster, GI24653722, Length=580, Percent_Identity=28.1034482758621, Blast_Score=210, Evalue=3e-54,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005844
- InterPro:   IPR016055
- InterPro:   IPR005845
- InterPro:   IPR005846
- InterPro:   IPR005843
- InterPro:   IPR016066
- InterPro:   IPR005841 [H]

Pfam domain/function: PF02878 PGM_PMM_I; PF02879 PGM_PMM_II; PF02880 PGM_PMM_III; PF00408 PGM_PMM_IV [H]

EC number: =5.4.2.2 [H]

Molecular weight: Translated: 63537; Mature: 63406

Theoretical pI: Translated: 4.74; Mature: 4.74

Prosite motif: PS00710 PGM_PMM

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSWQDTYNTWKNQATLETSLKQELTGMAGDDAALEDAFYEPMEFGTAGMRGVLGPGINRM
CCCCHHHHHHCCCHHHHHHHHHHHCCCCCCCHHHHHHHHCCHHHCCCCCCCCCCCCCCCE
NIYTVRQATEGLARFMDTLPAEVKERGVAISFDSRHHSEDFAHESARVLGQHGIKSYVFE
EEEEHHHHHHHHHHHHHHCCHHHHHCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHH
SLRPTPELSFTVRHLHTYAGIMITASHNPKQYNGYKIYGEDGGQMPPKESDLITSYIRKV
HCCCCCCHHHHHHHHHHHCCEEEEECCCCCCCCCEEEECCCCCCCCCCHHHHHHHHHHHH
DDVFAIAVADEQQLLADKTETIIGDDVDQDYLAKVKEVTINQKLVDEVGKDMKLVFTPLH
HHHEEEEECCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECC
GTGRMLGEKALKNAGFKNFSVVKEQAVADPEFSTVKFPNPEFPEAFKMAIDLGKKEGADV
CCHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCEEECCCCCCHHHHHHHHHCCCCCCCEE
LIAVDPDADRLGTAVRQPNGEYVLLTGNQIAAVLLHYILQANKDAGTLPTNAAAVKSIVS
EEEECCCHHHHHHHHCCCCCCEEEEECCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHH
SEFATKVAASYGVTMINVLTGFKYIAEQIEHFEATGEHTYMFGFEESYGYLIKPFVHDKD
HHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCEEECCCCCHH
AIQTTVLLAEVAAYYKQQGKNLYDGLQDLFKEYGYFREQTTSEEFDGVGGSDKIAALMTK
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCHHHHCCCCHHHCCCCCCHHHHHHHHH
FRSEAPTAFAGYDVTGTEDFQSQTESFADGHTAPIALPKANVLKYHLNDGTWIAIRPSGT
HHHCCCCEEECCCCCCCHHHHHHHHHHCCCCCCCEECCCCCEEEEEECCCEEEEEECCCC
EPKIKFYIGTLGSTLEEANDKLAKFEDAIQAFIKE
CCEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SWQDTYNTWKNQATLETSLKQELTGMAGDDAALEDAFYEPMEFGTAGMRGVLGPGINRM
CCCHHHHHHCCCHHHHHHHHHHHCCCCCCCHHHHHHHHCCHHHCCCCCCCCCCCCCCCE
NIYTVRQATEGLARFMDTLPAEVKERGVAISFDSRHHSEDFAHESARVLGQHGIKSYVFE
EEEEHHHHHHHHHHHHHHCCHHHHHCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHH
SLRPTPELSFTVRHLHTYAGIMITASHNPKQYNGYKIYGEDGGQMPPKESDLITSYIRKV
HCCCCCCHHHHHHHHHHHCCEEEEECCCCCCCCCEEEECCCCCCCCCCHHHHHHHHHHHH
DDVFAIAVADEQQLLADKTETIIGDDVDQDYLAKVKEVTINQKLVDEVGKDMKLVFTPLH
HHHEEEEECCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECC
GTGRMLGEKALKNAGFKNFSVVKEQAVADPEFSTVKFPNPEFPEAFKMAIDLGKKEGADV
CCHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCEEECCCCCCHHHHHHHHHCCCCCCCEE
LIAVDPDADRLGTAVRQPNGEYVLLTGNQIAAVLLHYILQANKDAGTLPTNAAAVKSIVS
EEEECCCHHHHHHHHCCCCCCEEEEECCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHH
SEFATKVAASYGVTMINVLTGFKYIAEQIEHFEATGEHTYMFGFEESYGYLIKPFVHDKD
HHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCEEECCCCCHH
AIQTTVLLAEVAAYYKQQGKNLYDGLQDLFKEYGYFREQTTSEEFDGVGGSDKIAALMTK
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCHHHHCCCCHHHCCCCCCHHHHHHHHH
FRSEAPTAFAGYDVTGTEDFQSQTESFADGHTAPIALPKANVLKYHLNDGTWIAIRPSGT
HHHCCCCEEECCCCCCCHHHHHHHHHHCCCCCCCEECCCCCEEEEEECCCEEEEEECCCC
EPKIKFYIGTLGSTLEEANDKLAKFEDAIQAFIKE
CCEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377; 2127799 [H]