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The map label for this gene is ucpA [H]

Identifier: 28199191

GI number: 28199191

Start: 1532117

End: 1532884

Strand: Reverse

Name: ucpA [H]

Synonym: PD1305

Alternate gene names: 28199191

Gene position: 1532884-1532117 (Counterclockwise)

Preceding gene: 77747687

Following gene: 28199187

Centisome position: 60.83

GC content: 55.34

Gene sequence:

>768_bases
ATGAATTTGCACAACAAAACGGTGCTCATTACTGGCGTGGCGTCTGGTATTGGTTCGGAGGTAGCACGGTTGGCACGTTT
TCACGGTGCCACGGTGATCGGTATCGATTGTCGACCAGTCACCATGACGTTGCATGGATTTTTCCATGCTGATCTTGGTG
ATCCTGCCTCCATTGATGCGTTAATCGCGCAGTTGCCCGAACGTATTGATGTGCTGGCTAATATTGCCGGTGTGCCGGGT
ACGGTGGCGGCTGACCTCGTTGCTAAGGTTAATTACTTGGGGTTGCGTCATTTGACTCAAGCCTTGCTGCCGCGCCTCGC
GCCGGGAGGCAATGTCATCAACATGACTTCGCTTTTGGGTGCCGAATGGCCGCAACGCTTGGAGTTGCACAAACAATTAG
CTGCCACCCCGGATTTCGCTGCGGGGCTGGATTGGTTGGTGGCGCATCCGGTGCCGGCTTCCATCTGCTATCAGTACTTT
AAGGAAGCACTGATCGTCTGGACCATGCTGCGGTCGCGTGATTGGTTTGCTGGGCATGGAGTGCGAGTGAATAGTGTGGC
ACCTGGGCCGGTCTTTACTCCGATTTTGGGTGACTTTGTCAGCATGTTGGGTCCGGATCGGGTACAGGCTGATGCGAGCA
AGATGAAGCGGCCTGCTTATGCGGATGAGGTTGCTGAGGCGGTGATCTTCCTGGCCTGTGATGCGGCCCGCTGGATCAAC
GGTGTCAATTTGCCGGTTGATGGTGGCTTGGCTGCCACGACGATTTGA

Upstream 100 bases:

>100_bases
GTTTTGGGATGGTTACGAAGTGAGAGTGTTGTCTCTAATAAAATCTTCACATCCACGTATGCTCGCTGCCACTGTGATTT
TTAGGTGGAGTTGTTGTTAC

Downstream 100 bases:

>100_bases
ATGTGTTGTCGATGATCCCTCTGGGCAGCGGTTATCTTGGGATACTGTGTTTCCCCCTTGGCCTTGCTTGGTCATGGACG
TGATGTTTATGTTGCGGTGA

Product: 3-alpha-hydroxysteroid dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 255; Mature: 255

Protein sequence:

>255_residues
MNLHNKTVLITGVASGIGSEVARLARFHGATVIGIDCRPVTMTLHGFFHADLGDPASIDALIAQLPERIDVLANIAGVPG
TVAADLVAKVNYLGLRHLTQALLPRLAPGGNVINMTSLLGAEWPQRLELHKQLAATPDFAAGLDWLVAHPVPASICYQYF
KEALIVWTMLRSRDWFAGHGVRVNSVAPGPVFTPILGDFVSMLGPDRVQADASKMKRPAYADEVAEAVIFLACDAARWIN
GVNLPVDGGLAATTI

Sequences:

>Translated_255_residues
MNLHNKTVLITGVASGIGSEVARLARFHGATVIGIDCRPVTMTLHGFFHADLGDPASIDALIAQLPERIDVLANIAGVPG
TVAADLVAKVNYLGLRHLTQALLPRLAPGGNVINMTSLLGAEWPQRLELHKQLAATPDFAAGLDWLVAHPVPASICYQYF
KEALIVWTMLRSRDWFAGHGVRVNSVAPGPVFTPILGDFVSMLGPDRVQADASKMKRPAYADEVAEAVIFLACDAARWIN
GVNLPVDGGLAATTI
>Mature_255_residues
MNLHNKTVLITGVASGIGSEVARLARFHGATVIGIDCRPVTMTLHGFFHADLGDPASIDALIAQLPERIDVLANIAGVPG
TVAADLVAKVNYLGLRHLTQALLPRLAPGGNVINMTSLLGAEWPQRLELHKQLAATPDFAAGLDWLVAHPVPASICYQYF
KEALIVWTMLRSRDWFAGHGVRVNSVAPGPVFTPILGDFVSMLGPDRVQADASKMKRPAYADEVAEAVIFLACDAARWIN
GVNLPVDGGLAATTI

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Escherichia coli, GI87082100, Length=277, Percent_Identity=29.9638989169675, Blast_Score=83, Evalue=2e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 27170; Mature: 27170

Theoretical pI: Translated: 6.72; Mature: 6.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLHNKTVLITGVASGIGSEVARLARFHGATVIGIDCRPVTMTLHGFFHADLGDPASIDA
CCCCCCEEEEEECHHHHHHHHHHHHHHCCCEEEEECCCEEEEEEEHEEECCCCCCHHHHH
LIAQLPERIDVLANIAGVPGTVAADLVAKVNYLGLRHLTQALLPRLAPGGNVINMTSLLG
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEHHHHHC
AEWPQRLELHKQLAATPDFAAGLDWLVAHPVPASICYQYFKEALIVWTMLRSRDWFAGHG
CCCHHHHHHHHHHHCCCCHHHCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCC
VRVNSVAPGPVFTPILGDFVSMLGPDRVQADASKMKRPAYADEVAEAVIFLACDAARWIN
EEECCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHC
GVNLPVDGGLAATTI
CCCCCCCCCEEECCC
>Mature Secondary Structure
MNLHNKTVLITGVASGIGSEVARLARFHGATVIGIDCRPVTMTLHGFFHADLGDPASIDA
CCCCCCEEEEEECHHHHHHHHHHHHHHCCCEEEEECCCEEEEEEEHEEECCCCCCHHHHH
LIAQLPERIDVLANIAGVPGTVAADLVAKVNYLGLRHLTQALLPRLAPGGNVINMTSLLG
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEHHHHHC
AEWPQRLELHKQLAATPDFAAGLDWLVAHPVPASICYQYFKEALIVWTMLRSRDWFAGHG
CCCHHHHHHHHHHHCCCCHHHCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCC
VRVNSVAPGPVFTPILGDFVSMLGPDRVQADASKMKRPAYADEVAEAVIFLACDAARWIN
EEECCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHC
GVNLPVDGGLAATTI
CCCCCCCCCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]