Click here to switch to the map view.

The map label for this gene is actP [H]

Identifier: 28199180

GI number: 28199180

Start: 1513581

End: 1515305

Strand: Reverse

Name: actP [H]

Synonym: PD1294

Alternate gene names: 28199180

Gene position: 1515305-1513581 (Counterclockwise)

Preceding gene: 28199181

Following gene: 28199179

Centisome position: 60.14

GC content: 50.78

Gene sequence:

>1725_bases
ATGAACATAGGCAGGCATCTTTTGTTGGTGTTGTTTGGGTGGTTGCCGGTGAGATTGGGGTTTGCTGCAGATGCGATAAG
TGTTGTCGATAAGCAGCCGGTAAATTGGGTGGCGATCACCATGTTCGCTGTTTTTGTGCTGATTACGTTATGGATCACTC
AGTGGGCCGCGAAGAAGACGCGATCATCTGCGGACTTTTATACGGCTGGGGGGACAGTCACCGGTTTCCAAAATGGTTTA
GCGATTGCCGGTGACTACGTGTCCGCTGCTTCGTTTCTTGGTATTACTTCGGCAGTGATGGCCAATGGCTATGATGGAAT
GCTCTATGCAATTGGCTTTTTAGTTGGTTGGCCGATTCTGACTTTTTTGATTGCTGAGCGGCTGCGCAATCTTGGCAAAT
ATACTTTTGCTGATGTGGTGGCTTACCGTTTTGCGGCGACGTCAGTTCGGTTGTTTGCTTCCGTTAGTACGTTGGTGGTG
GTGTTGTGTTATCTGATTGCACAGATGGTTGGGGCCGGTGCGCTGATTAGGTTGTTGTTTGGTTTAGATTATTGGGTTGC
AATGGTGCTGGTTGGCGGACTGATGATGGTGTACGTGTTGTTTGGTGGGATGGCTGCAACCACCTGGGTACAGATTATTA
AGGCGGTGCTGTTGCTGATTGGTGCGACTTTCATGGCAGTCATGATCATGCGCAGGTTCGGTTTTAATTTTGAGGGGTTG
TTTGCGAGTGCGGTGGAGGTCAAGACTCAAATTGCGATGGCGGGCGGTAAATCTGGGGAGGAGGCTAAAGCGTTAGGGCT
ATCGATCATGGCGCCGGGTAGTTTTATCAAGGATCCAATTTCGGCGATTTCATTAGGCATCGCATTGGTATTCGGTACTG
CGGGGTTACCACATATTTTAATGCGCTTCTTCACCGTGCCTGACGCCAGACAGGCGCGTCATTCGGTGTTGTGGGCGATT
ACCTGGATCGGTTATTGCTACATCTTGATGTTTATCATTGGATTCGGTGCGATTGTGCTTGTGTTAGCGAATCCGCAGTA
TGCCGATATCGCTTCTGGCACCATCCGCGGTGGTCAGGGTGCAGCCAATATGGCTGCGGTGCTTGTCGCCAAAGTAGTCG
GGGGTAATGTGTTCATGGGGTTTGTCTCTGCTGTGGCATTTGCGACGATTCTGGCGGTGGTAGCAGGGTTGGCGTTGTCT
GGTGCATCGGCGGTGTCACATGATGTGTATGCGATGGTGATTAAGCAGGGTAAGCCATCTTCGGATACTGAGTTGTTGGT
CTCGCGTGTGACCACGGCAGTATTAGGTGTGGTTGCGGTGTTGCTGGGGATCGTGTTTCAGAAGCAGAATGTTGCGTTCA
TGGTGTCATTAGCATTTGCGATTGCAGCGTCGGCTAATTTCCCTGTACTGGTTCTGTCGCTGTTTTGGAAGAATTGTACG
ACGAGGGGTGCGGTAATCGGTGGTTTTCTCGGTTTGATTTCTTCGTTGGTGTTGACGGTGTTATCACCTTCGGTGTGGGT
CGATACGTTGGGTCATTCGGTGGATTCGGTGCGATTCCCTTACACGTCGCCGGCATTGTTTTCCATGACCATAGGGTTTG
TCGGTATTTGGTTGTTTTCGGTGCTGGATCGTAGTGGCCGGGCGGCGAAGGAGCGCGTTGCGTTTAAGGCGCAGCAGGTA
CGTGCTGAAACTGGATTAGGTGCTTCCAAAATGTCACCCAATTGA

Upstream 100 bases:

>100_bases
GGGTGATGCTGTTCGCCATTATTGTTACTGCGGTTTATGTTTTTTTTTCCAACATTGTCTACGACAAATTAAGTCGTAAC
ATTCTTGAGGATGCCTGTAA

Downstream 100 bases:

>100_bases
TTCGCTTAGCATTAAAAGATGTACGGCGTTGGAGTGTCTGCGACCTTGTGTACGGATTGTTTGGGTTAGGAGTTGGTGTC
GATTGATGCGAGTCGTTGGC

Product: acetate permease

Products: NA

Alternate protein names: Acetate permease; Acetate transporter ActP [H]

Number of amino acids: Translated: 574; Mature: 574

Protein sequence:

>574_residues
MNIGRHLLLVLFGWLPVRLGFAADAISVVDKQPVNWVAITMFAVFVLITLWITQWAAKKTRSSADFYTAGGTVTGFQNGL
AIAGDYVSAASFLGITSAVMANGYDGMLYAIGFLVGWPILTFLIAERLRNLGKYTFADVVAYRFAATSVRLFASVSTLVV
VLCYLIAQMVGAGALIRLLFGLDYWVAMVLVGGLMMVYVLFGGMAATTWVQIIKAVLLLIGATFMAVMIMRRFGFNFEGL
FASAVEVKTQIAMAGGKSGEEAKALGLSIMAPGSFIKDPISAISLGIALVFGTAGLPHILMRFFTVPDARQARHSVLWAI
TWIGYCYILMFIIGFGAIVLVLANPQYADIASGTIRGGQGAANMAAVLVAKVVGGNVFMGFVSAVAFATILAVVAGLALS
GASAVSHDVYAMVIKQGKPSSDTELLVSRVTTAVLGVVAVLLGIVFQKQNVAFMVSLAFAIAASANFPVLVLSLFWKNCT
TRGAVIGGFLGLISSLVLTVLSPSVWVDTLGHSVDSVRFPYTSPALFSMTIGFVGIWLFSVLDRSGRAAKERVAFKAQQV
RAETGLGASKMSPN

Sequences:

>Translated_574_residues
MNIGRHLLLVLFGWLPVRLGFAADAISVVDKQPVNWVAITMFAVFVLITLWITQWAAKKTRSSADFYTAGGTVTGFQNGL
AIAGDYVSAASFLGITSAVMANGYDGMLYAIGFLVGWPILTFLIAERLRNLGKYTFADVVAYRFAATSVRLFASVSTLVV
VLCYLIAQMVGAGALIRLLFGLDYWVAMVLVGGLMMVYVLFGGMAATTWVQIIKAVLLLIGATFMAVMIMRRFGFNFEGL
FASAVEVKTQIAMAGGKSGEEAKALGLSIMAPGSFIKDPISAISLGIALVFGTAGLPHILMRFFTVPDARQARHSVLWAI
TWIGYCYILMFIIGFGAIVLVLANPQYADIASGTIRGGQGAANMAAVLVAKVVGGNVFMGFVSAVAFATILAVVAGLALS
GASAVSHDVYAMVIKQGKPSSDTELLVSRVTTAVLGVVAVLLGIVFQKQNVAFMVSLAFAIAASANFPVLVLSLFWKNCT
TRGAVIGGFLGLISSLVLTVLSPSVWVDTLGHSVDSVRFPYTSPALFSMTIGFVGIWLFSVLDRSGRAAKERVAFKAQQV
RAETGLGASKMSPN
>Mature_574_residues
MNIGRHLLLVLFGWLPVRLGFAADAISVVDKQPVNWVAITMFAVFVLITLWITQWAAKKTRSSADFYTAGGTVTGFQNGL
AIAGDYVSAASFLGITSAVMANGYDGMLYAIGFLVGWPILTFLIAERLRNLGKYTFADVVAYRFAATSVRLFASVSTLVV
VLCYLIAQMVGAGALIRLLFGLDYWVAMVLVGGLMMVYVLFGGMAATTWVQIIKAVLLLIGATFMAVMIMRRFGFNFEGL
FASAVEVKTQIAMAGGKSGEEAKALGLSIMAPGSFIKDPISAISLGIALVFGTAGLPHILMRFFTVPDARQARHSVLWAI
TWIGYCYILMFIIGFGAIVLVLANPQYADIASGTIRGGQGAANMAAVLVAKVVGGNVFMGFVSAVAFATILAVVAGLALS
GASAVSHDVYAMVIKQGKPSSDTELLVSRVTTAVLGVVAVLLGIVFQKQNVAFMVSLAFAIAASANFPVLVLSLFWKNCT
TRGAVIGGFLGLISSLVLTVLSPSVWVDTLGHSVDSVRFPYTSPALFSMTIGFVGIWLFSVLDRSGRAAKERVAFKAQQV
RAETGLGASKMSPN

Specific function: Transports acetate [H]

COG id: COG4147

COG function: function code R; Predicted symporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family [H]

Homologues:

Organism=Homo sapiens, GI310128183, Length=485, Percent_Identity=23.7113402061856, Blast_Score=92, Evalue=1e-18,
Organism=Escherichia coli, GI1790503, Length=550, Percent_Identity=61.0909090909091, Blast_Score=667, Evalue=0.0,
Organism=Escherichia coli, GI1787251, Length=469, Percent_Identity=24.9466950959488, Blast_Score=83, Evalue=4e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014083
- InterPro:   IPR001734
- InterPro:   IPR018212
- InterPro:   IPR019900 [H]

Pfam domain/function: PF00474 SSF [H]

EC number: NA

Molecular weight: Translated: 60836; Mature: 60836

Theoretical pI: Translated: 10.18; Mature: 10.18

Prosite motif: PS00456 NA_SOLUT_SYMP_1 ; PS50283 NA_SOLUT_SYMP_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure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HHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA