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The map label for this gene is yflS [H]

Identifier: 62185196

GI number: 62185196

Start: 657686

End: 659098

Strand: Direct

Name: yflS [H]

Synonym: CAB580

Alternate gene names: 62185196

Gene position: 657686-659098 (Clockwise)

Preceding gene: 62185195

Following gene: 62185197

Centisome position: 57.47

GC content: 43.45

Gene sequence:

>1413_bases
GTGAAAAAACAAAAACGATTCCTGTCTCTTTTATTTCTCACATTTGTACTCTTAGGCATATGGTTTTGTCCTCATCCCGA
AGCAATCAATCCTAACGCTTGGCATCTATTCGCTGTATTCACAACGACAATTTTAGGTATTATCCTGCAGCCCGTGCCTA
TGGGAGCCATAGTCATTATCGGGATTTCTACACTGCTACTTACGCAAACACTAACCCTAGAACAGGGTCTATCGGGATTT
CATGATCCTATAGCTTGGTTGGTCTTTCTATCCTTTTCCATAGCCAAAGGCATTATTAAAACCGGTCTCGGAGAACGCGT
GGCTTACTTTTTTGTAAGTATCTTAGGGAAAAATCCTCTGGGCTTAAGCTATGGGTTGGTCATTACAGATTTTCTATTAG
CGCCTGCGATTCCTAGTGTTACAGCACGATCCGGGGGGATTCTCTATCCCGTAGTGATGGGGCTATCAGAATCTTTCGGA
AGCTCCGCAGAAAAAGGAACAGAAAGCCTGATCGGCTCCTTCCTAATCAAAGTTGCTTATCAAAGTTCTGTAATTACCAG
TGCCATGTTTCTAACTGCTATGGCCGGTAACCCTTTATTAGCCGCTTTAGCAAGCAATGCAGGCATAGCACTGACTTGGG
CAACATGGGCAAAGGCAGCCGTATTCCCCGGATTATTGAGTTTAGTGCTGATGCCTATCGTCCTTTATAAGCTCTACCCA
CCGACAATTACCTCTTGTGAGGAAGCCATTCGCACAGCAAAATTACGTCTTAAAGAAATGGGCCCTTTGAAAAAAGGAGA
AAAGATCATCTTGATGATTTTTACTTTGCTTGTTGTTCTATGGACATTCGGAGACCTACTAAGAATATCAGCGACTACAG
CAGCATTAATTGGCCTATCACTGCTCATCCTGACAAATATTTTAGATTGGCATAAAGATGTCATGGCCAATACCACTGCC
TGGGAAACATTTATTTGGTTCGGGGCTCTGATTATGATGGCATCGTTCCTCAATCAATTGGGTTTCATTCCCCTCATTGG
AGATAGCGTAGCCGCAGGAGTTGCAGGACTATCTTGGAAAATTGGCTTCCCTATTCTATTCTTGATGTACTTTTACTCAC
ATTACCTATTTGCAAGTAACACAGCGCACATCGGCGCCATGTTTCCTGTATTTCTCGCTGTTTCCATCGCTTTAGGGACC
AACCCCATTTTCGCCTGTTTAGTACTCGCTTTTTCCAGTAACCTGTTTGGAGGACTCACTCACTATGGTTCGGGACCGGC
ACCCCTATACTTTGGATCACAACTCGTTTCTATTAAGGATTGGTGGCAATCTGGTTTTATTCTCAGTATTGTCAATATTG
CCATTTGGGTAGGTATCGGCAGCCTGTGGTGGAAAATTCTTGGTCTTATCTAA

Upstream 100 bases:

>100_bases
GACACCCTAGAAGAAATGGAAAAATGGCTCGAAGATTTTCCTATAGAGCCTTAAACCCTCTCGGGATTTTCCAACAGACT
ATAACGCAAAGAGGTCCCAA

Downstream 100 bases:

>100_bases
GAAATATTCCTCAAACAGCGAGAAAGAAAACCTTCTAACCAGAAGGTTTTCTTTTATTCGATAAAGAAAAACACAGCGAA
TTTACGAAAATACTGTATCC

Product: putative sodium:sulfate symporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 470; Mature: 470

Protein sequence:

>470_residues
MKKQKRFLSLLFLTFVLLGIWFCPHPEAINPNAWHLFAVFTTTILGIILQPVPMGAIVIIGISTLLLTQTLTLEQGLSGF
HDPIAWLVFLSFSIAKGIIKTGLGERVAYFFVSILGKNPLGLSYGLVITDFLLAPAIPSVTARSGGILYPVVMGLSESFG
SSAEKGTESLIGSFLIKVAYQSSVITSAMFLTAMAGNPLLAALASNAGIALTWATWAKAAVFPGLLSLVLMPIVLYKLYP
PTITSCEEAIRTAKLRLKEMGPLKKGEKIILMIFTLLVVLWTFGDLLRISATTAALIGLSLLILTNILDWHKDVMANTTA
WETFIWFGALIMMASFLNQLGFIPLIGDSVAAGVAGLSWKIGFPILFLMYFYSHYLFASNTAHIGAMFPVFLAVSIALGT
NPIFACLVLAFSSNLFGGLTHYGSGPAPLYFGSQLVSIKDWWQSGFILSIVNIAIWVGIGSLWWKILGLI

Sequences:

>Translated_470_residues
MKKQKRFLSLLFLTFVLLGIWFCPHPEAINPNAWHLFAVFTTTILGIILQPVPMGAIVIIGISTLLLTQTLTLEQGLSGF
HDPIAWLVFLSFSIAKGIIKTGLGERVAYFFVSILGKNPLGLSYGLVITDFLLAPAIPSVTARSGGILYPVVMGLSESFG
SSAEKGTESLIGSFLIKVAYQSSVITSAMFLTAMAGNPLLAALASNAGIALTWATWAKAAVFPGLLSLVLMPIVLYKLYP
PTITSCEEAIRTAKLRLKEMGPLKKGEKIILMIFTLLVVLWTFGDLLRISATTAALIGLSLLILTNILDWHKDVMANTTA
WETFIWFGALIMMASFLNQLGFIPLIGDSVAAGVAGLSWKIGFPILFLMYFYSHYLFASNTAHIGAMFPVFLAVSIALGT
NPIFACLVLAFSSNLFGGLTHYGSGPAPLYFGSQLVSIKDWWQSGFILSIVNIAIWVGIGSLWWKILGLI
>Mature_470_residues
MKKQKRFLSLLFLTFVLLGIWFCPHPEAINPNAWHLFAVFTTTILGIILQPVPMGAIVIIGISTLLLTQTLTLEQGLSGF
HDPIAWLVFLSFSIAKGIIKTGLGERVAYFFVSILGKNPLGLSYGLVITDFLLAPAIPSVTARSGGILYPVVMGLSESFG
SSAEKGTESLIGSFLIKVAYQSSVITSAMFLTAMAGNPLLAALASNAGIALTWATWAKAAVFPGLLSLVLMPIVLYKLYP
PTITSCEEAIRTAKLRLKEMGPLKKGEKIILMIFTLLVVLWTFGDLLRISATTAALIGLSLLILTNILDWHKDVMANTTA
WETFIWFGALIMMASFLNQLGFIPLIGDSVAAGVAGLSWKIGFPILFLMYFYSHYLFASNTAHIGAMFPVFLAVSIALGT
NPIFACLVLAFSSNLFGGLTHYGSGPAPLYFGSQLVSIKDWWQSGFILSIVNIAIWVGIGSLWWKILGLI

Specific function: Might be a malate transporter [H]

COG id: COG0471

COG function: function code P; Di- and tricarboxylate transporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the SLC13A transporter (TC 2.A.47) family [H]

Homologues:

Organism=Escherichia coli, GI1786986, Length=474, Percent_Identity=32.4894514767932, Blast_Score=260, Evalue=1e-70,
Organism=Escherichia coli, GI1786829, Length=490, Percent_Identity=34.2857142857143, Blast_Score=252, Evalue=3e-68,
Organism=Escherichia coli, GI1789444, Length=463, Percent_Identity=34.1252699784017, Blast_Score=238, Evalue=7e-64,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001898 [H]

Pfam domain/function: PF00939 Na_sulph_symp [H]

EC number: NA

Molecular weight: Translated: 50899; Mature: 50899

Theoretical pI: Translated: 9.54; Mature: 9.54

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKQKRFLSLLFLTFVLLGIWFCPHPEAINPNAWHLFAVFTTTILGIILQPVPMGAIVII
CCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHH
GISTLLLTQTLTLEQGLSGFHDPIAWLVFLSFSIAKGIIKTGLGERVAYFFVSILGKNPL
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCC
GLSYGLVITDFLLAPAIPSVTARSGGILYPVVMGLSESFGSSAEKGTESLIGSFLIKVAY
CCHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
QSSVITSAMFLTAMAGNPLLAALASNAGIALTWATWAKAAVFPGLLSLVLMPIVLYKLYP
HHHHHHHHHHHHHHCCCHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCC
PTITSCEEAIRTAKLRLKEMGPLKKGEKIILMIFTLLVVLWTFGDLLRISATTAALIGLS
CCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLILTNILDWHKDVMANTTAWETFIWFGALIMMASFLNQLGFIPLIGDSVAAGVAGLSWK
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEECCHHHHHHCCCCEE
IGFPILFLMYFYSHYLFASNTAHIGAMFPVFLAVSIALGTNPIFACLVLAFSSNLFGGLT
HHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCHH
HYGSGPAPLYFGSQLVSIKDWWQSGFILSIVNIAIWVGIGSLWWKILGLI
HCCCCCCCCHHCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKKQKRFLSLLFLTFVLLGIWFCPHPEAINPNAWHLFAVFTTTILGIILQPVPMGAIVII
CCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHH
GISTLLLTQTLTLEQGLSGFHDPIAWLVFLSFSIAKGIIKTGLGERVAYFFVSILGKNPL
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCC
GLSYGLVITDFLLAPAIPSVTARSGGILYPVVMGLSESFGSSAEKGTESLIGSFLIKVAY
CCHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
QSSVITSAMFLTAMAGNPLLAALASNAGIALTWATWAKAAVFPGLLSLVLMPIVLYKLYP
HHHHHHHHHHHHHHCCCHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCC
PTITSCEEAIRTAKLRLKEMGPLKKGEKIILMIFTLLVVLWTFGDLLRISATTAALIGLS
CCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLILTNILDWHKDVMANTTAWETFIWFGALIMMASFLNQLGFIPLIGDSVAAGVAGLSWK
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEECCHHHHHHCCCCEE
IGFPILFLMYFYSHYLFASNTAHIGAMFPVFLAVSIALGTNPIFACLVLAFSSNLFGGLT
HHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCHH
HYGSGPAPLYFGSQLVSIKDWWQSGFILSIVNIAIWVGIGSLWWKILGLI
HCCCCCCCCHHCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9272861; 9384377; 12949159 [H]