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The map label for this gene is ftsW [H]

Identifier: 28572927

GI number: 28572927

Start: 889664

End: 891010

Strand: Direct

Name: ftsW [H]

Synonym: TW786

Alternate gene names: 28572927

Gene position: 889664-891010 (Clockwise)

Preceding gene: 28572926

Following gene: 28572928

Centisome position: 96.08

GC content: 45.14

Gene sequence:

>1347_bases
ATGTATAGGCTTTATTTGGGTATGTCAAAACTAATACGTCAAAGACGAAATATCGAGCTGGCCCTGATAATAATCGTCAT
TCTCATCGGTAATGCATGTCTGGTACTGGTTGAGCTTGGGGTGTCGGAAAGCCTGCACGCTAATGTGTTTATCTTCGCGG
GGATTTTTTACTGCGCAGCCATAATCATGCACACCGTGATCCGATTCTACGCCGCAAATGCAGAACCTTTTATCTTTCCA
ATCGCATTGTTGCTAAACAGCCTCGGAATCGCAGAGATATACCGAATTGATATTGAGAATAAAACCTCTTACGGCACTAA
GCAAATTATCTGGTCAATACTTAGTCTCCTGGTCGCATCGGTGGTTATTGTTACCATACGGAATTATCGAGTTCTGCAGC
GCTATACATATTTACTGGGGCTTGTGTCATGCGCATTGCTTTTGCTGCCAATCCTGCCGGGGATTGGCGAATCTGTCAGC
GGTGCAAGAATATGGATAAAGCTTGGCGGTCTTTCGTTCCAGCCGGGCGAATTGGTAAAGATCACTTTGGCAATCTTTTT
TGCAAGCTATCTGTATTCACATCGCGAGACTTTGATTGCAAAACAATCAGCCAAAATCTTTCTGTCCAAAATACGCAATT
TTGCGCCAATTTTTTCCGTATGGATTCTGTGTGTTCTGATTATCGCAGTCCAGCGAGACCTTGGGACGGGGGTCCTTTAC
TTCGCATTGTTTATTATCCTGACATATCTGGCCCTTTCCAGGATGCGGCTATTAATCATTGGCGGCGTAATGTTGCTTGC
TGGAACATTTTTTGCGGCGAGAATTATGACCTATGTTGGATATCGCATTGATGTTTGGCTCAATGCGTTTGATCAGTCTG
TATTCGAACGCGCCTTTGGTGGAAGCTACCAGCTCGTACAAGGAATATTCGGGATGGCTTTCGGTGGATTACTTGGCACA
GGTCTCGGGCGAGGCTATCCAAGCATAACCCCGTTACCACAAAGCGACTACATATTGGCTAGCCTGGGTGAGGAGCTTGG
ATTAGCCGGTTTTAGCCTAATAATGATTATGTATATGACAATTTTTTTTCAAGCTATAAAAGTAGCTCTGGAGGCAAATG
ATGAATTTGCAAAGCTCCTCACCGCGGGTTTAGGGTGCATCATAGCTGTACAAGTGTTTATAGTCGCCGGCGGAATAACA
CGCGTTATTCCGCTTACGGGACTTACCGCGCCATTCTTAGCATCGGGAGGGTCAAGCTTATTCGTGAACTGGATAATTGT
TAGCCTGATTATCCGTATATCCGATAACCTGCGCAACTCTCCCGCGTTGAATGAATGGAAGACATGA

Upstream 100 bases:

>100_bases
TGAAACAAGATTTTACGCGCCTATTCTCACCCAATGGAGTCCGCATTCGGGGCATTGATTCGTGTGGAATTTCAAGCTCG
CATAGAGCACTCAACAGAGT

Downstream 100 bases:

>100_bases
AGGTCCAGATACAACAACCCTGGCGGCATAGGTAGTAACAATATGTCCAACATGCTATCGGTCAAACATGTAGACAAAAA
AAACCGTGACGGGCGCGCAA

Product: FtsW/RodA/SpoVE family cell cycle protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 448; Mature: 448

Protein sequence:

>448_residues
MYRLYLGMSKLIRQRRNIELALIIIVILIGNACLVLVELGVSESLHANVFIFAGIFYCAAIIMHTVIRFYAANAEPFIFP
IALLLNSLGIAEIYRIDIENKTSYGTKQIIWSILSLLVASVVIVTIRNYRVLQRYTYLLGLVSCALLLLPILPGIGESVS
GARIWIKLGGLSFQPGELVKITLAIFFASYLYSHRETLIAKQSAKIFLSKIRNFAPIFSVWILCVLIIAVQRDLGTGVLY
FALFIILTYLALSRMRLLIIGGVMLLAGTFFAARIMTYVGYRIDVWLNAFDQSVFERAFGGSYQLVQGIFGMAFGGLLGT
GLGRGYPSITPLPQSDYILASLGEELGLAGFSLIMIMYMTIFFQAIKVALEANDEFAKLLTAGLGCIIAVQVFIVAGGIT
RVIPLTGLTAPFLASGGSSLFVNWIIVSLIIRISDNLRNSPALNEWKT

Sequences:

>Translated_448_residues
MYRLYLGMSKLIRQRRNIELALIIIVILIGNACLVLVELGVSESLHANVFIFAGIFYCAAIIMHTVIRFYAANAEPFIFP
IALLLNSLGIAEIYRIDIENKTSYGTKQIIWSILSLLVASVVIVTIRNYRVLQRYTYLLGLVSCALLLLPILPGIGESVS
GARIWIKLGGLSFQPGELVKITLAIFFASYLYSHRETLIAKQSAKIFLSKIRNFAPIFSVWILCVLIIAVQRDLGTGVLY
FALFIILTYLALSRMRLLIIGGVMLLAGTFFAARIMTYVGYRIDVWLNAFDQSVFERAFGGSYQLVQGIFGMAFGGLLGT
GLGRGYPSITPLPQSDYILASLGEELGLAGFSLIMIMYMTIFFQAIKVALEANDEFAKLLTAGLGCIIAVQVFIVAGGIT
RVIPLTGLTAPFLASGGSSLFVNWIIVSLIIRISDNLRNSPALNEWKT
>Mature_448_residues
MYRLYLGMSKLIRQRRNIELALIIIVILIGNACLVLVELGVSESLHANVFIFAGIFYCAAIIMHTVIRFYAANAEPFIFP
IALLLNSLGIAEIYRIDIENKTSYGTKQIIWSILSLLVASVVIVTIRNYRVLQRYTYLLGLVSCALLLLPILPGIGESVS
GARIWIKLGGLSFQPGELVKITLAIFFASYLYSHRETLIAKQSAKIFLSKIRNFAPIFSVWILCVLIIAVQRDLGTGVLY
FALFIILTYLALSRMRLLIIGGVMLLAGTFFAARIMTYVGYRIDVWLNAFDQSVFERAFGGSYQLVQGIFGMAFGGLLGT
GLGRGYPSITPLPQSDYILASLGEELGLAGFSLIMIMYMTIFFQAIKVALEANDEFAKLLTAGLGCIIAVQVFIVAGGIT
RVIPLTGLTAPFLASGGSSLFVNWIIVSLIIRISDNLRNSPALNEWKT

Specific function: This is a septum-peptidoglycan biosynthetic protein, involved in cell wall formation. Plays a role in the stabilization of the ftsZ ring during cell division [H]

COG id: COG0772

COG function: function code D; Bacterial cell division membrane protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsW/rodA/spoVE family [H]

Homologues:

Organism=Escherichia coli, GI1786277, Length=345, Percent_Identity=28.695652173913, Blast_Score=115, Evalue=5e-27,
Organism=Escherichia coli, GI1786853, Length=317, Percent_Identity=26.813880126183, Blast_Score=77, Evalue=3e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001182
- InterPro:   IPR018365 [H]

Pfam domain/function: PF01098 FTSW_RODA_SPOVE [H]

EC number: NA

Molecular weight: Translated: 49319; Mature: 49319

Theoretical pI: Translated: 9.62; Mature: 9.62

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYRLYLGMSKLIRQRRNIELALIIIVILIGNACLVLVELGVSESLHANVFIFAGIFYCAA
CEEHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHH
IIMHTVIRFYAANAEPFIFPIALLLNSLGIAEIYRIDIENKTSYGTKQIIWSILSLLVAS
HHHHHHHHHHHCCCCCHHHHHHHHHCCCCHHHEEEEECCCCCCCCHHHHHHHHHHHHHHH
VVIVTIRNYRVLQRYTYLLGLVSCALLLLPILPGIGESVSGARIWIKLGGLSFQPGELVK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCCCCHHHH
ITLAIFFASYLYSHRETLIAKQSAKIFLSKIRNFAPIFSVWILCVLIIAVQRDLGTGVLY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
FALFIILTYLALSRMRLLIIGGVMLLAGTFFAARIMTYVGYRIDVWLNAFDQSVFERAFG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHCC
GSYQLVQGIFGMAFGGLLGTGLGRGYPSITPLPQSDYILASLGEELGLAGFSLIMIMYMT
CCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHCHHHHHHHHHHHHH
IFFQAIKVALEANDEFAKLLTAGLGCIIAVQVFIVAGGITRVIPLTGLTAPFLASGGSSL
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCHHHHHCCCCHH
FVNWIIVSLIIRISDNLRNSPALNEWKT
HHHHHHHHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure
MYRLYLGMSKLIRQRRNIELALIIIVILIGNACLVLVELGVSESLHANVFIFAGIFYCAA
CEEHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHH
IIMHTVIRFYAANAEPFIFPIALLLNSLGIAEIYRIDIENKTSYGTKQIIWSILSLLVAS
HHHHHHHHHHHCCCCCHHHHHHHHHCCCCHHHEEEEECCCCCCCCHHHHHHHHHHHHHHH
VVIVTIRNYRVLQRYTYLLGLVSCALLLLPILPGIGESVSGARIWIKLGGLSFQPGELVK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCCCCHHHH
ITLAIFFASYLYSHRETLIAKQSAKIFLSKIRNFAPIFSVWILCVLIIAVQRDLGTGVLY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
FALFIILTYLALSRMRLLIIGGVMLLAGTFFAARIMTYVGYRIDVWLNAFDQSVFERAFG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHCC
GSYQLVQGIFGMAFGGLLGTGLGRGYPSITPLPQSDYILASLGEELGLAGFSLIMIMYMT
CCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHCHHHHHHHHHHHHH
IFFQAIKVALEANDEFAKLLTAGLGCIIAVQVFIVAGGITRVIPLTGLTAPFLASGGSSL
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCHHHHHCCCCHH
FVNWIIVSLIIRISDNLRNSPALNEWKT
HHHHHHHHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]