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The map label for this gene is phoP [H]

Identifier: 23099620

GI number: 23099620

Start: 2199003

End: 2199698

Strand: Reverse

Name: phoP [H]

Synonym: OB2165

Alternate gene names: 23099620

Gene position: 2199698-2199003 (Counterclockwise)

Preceding gene: 23099621

Following gene: 23099619

Centisome position: 60.59

GC content: 32.61

Gene sequence:

>696_bases
ATGAGTAAAAGAATATTAATCGTAGATGATGAAAAGTCTATTGTAACATTACTAAAATATAATATGGAAAATTCAGGTTT
TGAAACGGATGTTGCTTATAATGGACAAGAAGCGATTAATAAAGCAGAGGCAAGCATGTATGATTTAATTGTATTGGATT
TAATGCTTCCTGAAGTCGATGGGATGGAGGTATGCCGTACATTAAGAATGAATCAAGTAAATACACCAATTCTTATGTTA
ACTGCAAAAGATGAGGAATTTGATAAGGTACTTGGTTTAGAAATGGGGGCAGATGATTATTTAACGAAACCATTTAGCCC
AAAGGAAGTTATTGCAAGAGTAAAAGCAATTTTACGACGATCCCAATTATCTAATAACCATGGGTTTCACGTATTAAAAA
TAGGGGAATTAAGTATATATCCTGAAAGATATGAAGCAGAAATGAGTAATAATATCATTACTTTCACTCGAAAGGAATTT
GAATTATTGTATCATCTTGCAAAACATAAAGGGAAAGTAATATCACGGGATCAGTTATTGAGTAGTGTATGGGATTATGA
CTTTATTGGAGATACTCGAATTGTAGATGTTCATATTAGTCATCTTCGAGATAAAATAGAACCTAATTCTAAAAAGCCTG
TATATATCAAGACAGTACGCGGCTTGGGCTATAAAATGGAGGAGCCTGTTTCATGA

Upstream 100 bases:

>100_bases
TTAACATTTTGTGATTCGTTATACGTAGCTGGATAATAATGATAATATAAGAGTATAGAGTTGGTAATAATTTGGTAAGG
AAATGCTAGGGGGAGTACTA

Downstream 100 bases:

>100_bases
AAGTAATCTTTTCTAGAACTTTACTTCCAAGTATGATTATTACTATATTGAGCTTATTATTGACTGGTTGGCTGATCGTT
CAAGCTGAGTCTAATTGGAT

Product: two-component response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 231; Mature: 230

Protein sequence:

>231_residues
MSKRILIVDDEKSIVTLLKYNMENSGFETDVAYNGQEAINKAEASMYDLIVLDLMLPEVDGMEVCRTLRMNQVNTPILML
TAKDEEFDKVLGLEMGADDYLTKPFSPKEVIARVKAILRRSQLSNNHGFHVLKIGELSIYPERYEAEMSNNIITFTRKEF
ELLYHLAKHKGKVISRDQLLSSVWDYDFIGDTRIVDVHISHLRDKIEPNSKKPVYIKTVRGLGYKMEEPVS

Sequences:

>Translated_231_residues
MSKRILIVDDEKSIVTLLKYNMENSGFETDVAYNGQEAINKAEASMYDLIVLDLMLPEVDGMEVCRTLRMNQVNTPILML
TAKDEEFDKVLGLEMGADDYLTKPFSPKEVIARVKAILRRSQLSNNHGFHVLKIGELSIYPERYEAEMSNNIITFTRKEF
ELLYHLAKHKGKVISRDQLLSSVWDYDFIGDTRIVDVHISHLRDKIEPNSKKPVYIKTVRGLGYKMEEPVS
>Mature_230_residues
SKRILIVDDEKSIVTLLKYNMENSGFETDVAYNGQEAINKAEASMYDLIVLDLMLPEVDGMEVCRTLRMNQVNTPILMLT
AKDEEFDKVLGLEMGADDYLTKPFSPKEVIARVKAILRRSQLSNNHGFHVLKIGELSIYPERYEAEMSNNIITFTRKEFE
LLYHLAKHKGKVISRDQLLSSVWDYDFIGDTRIVDVHISHLRDKIEPNSKKPVYIKTVRGLGYKMEEPVS

Specific function: Member of the two-component regulatory system phoP/phoR involved in the regulation of alkaline phosphatase genes phoA and phoB and of phosphodiesterase [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI2367329, Length=228, Percent_Identity=40.3508771929825, Blast_Score=165, Evalue=2e-42,
Organism=Escherichia coli, GI1786784, Length=227, Percent_Identity=41.4096916299559, Blast_Score=163, Evalue=1e-41,
Organism=Escherichia coli, GI1786599, Length=227, Percent_Identity=39.2070484581498, Blast_Score=162, Evalue=2e-41,
Organism=Escherichia coli, GI1790860, Length=222, Percent_Identity=38.7387387387387, Blast_Score=160, Evalue=8e-41,
Organism=Escherichia coli, GI1788394, Length=231, Percent_Identity=40.2597402597403, Blast_Score=159, Evalue=1e-40,
Organism=Escherichia coli, GI1789809, Length=225, Percent_Identity=36.4444444444444, Blast_Score=153, Evalue=1e-38,
Organism=Escherichia coli, GI87082012, Length=224, Percent_Identity=37.9464285714286, Blast_Score=149, Evalue=1e-37,
Organism=Escherichia coli, GI1790552, Length=223, Percent_Identity=36.322869955157, Blast_Score=141, Evalue=3e-35,
Organism=Escherichia coli, GI1789402, Length=225, Percent_Identity=34.2222222222222, Blast_Score=137, Evalue=4e-34,
Organism=Escherichia coli, GI1787375, Length=226, Percent_Identity=34.5132743362832, Blast_Score=129, Evalue=2e-31,
Organism=Escherichia coli, GI1786911, Length=222, Percent_Identity=33.3333333333333, Blast_Score=128, Evalue=4e-31,
Organism=Escherichia coli, GI145693140, Length=229, Percent_Identity=34.4978165938865, Blast_Score=122, Evalue=2e-29,
Organism=Escherichia coli, GI1790863, Length=235, Percent_Identity=33.1914893617021, Blast_Score=114, Evalue=7e-27,
Organism=Escherichia coli, GI1787229, Length=236, Percent_Identity=30.0847457627119, Blast_Score=102, Evalue=2e-23,
Organism=Escherichia coli, GI1788550, Length=107, Percent_Identity=36.4485981308411, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1790437, Length=101, Percent_Identity=30.6930693069307, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1788713, Length=102, Percent_Identity=35.2941176470588, Blast_Score=61, Evalue=5e-11,
Organism=Escherichia coli, GI1788191, Length=120, Percent_Identity=26.6666666666667, Blast_Score=61, Evalue=5e-11,
Organism=Escherichia coli, GI1790299, Length=111, Percent_Identity=27.027027027027, Blast_Score=61, Evalue=7e-11,
Organism=Escherichia coli, GI1790576, Length=101, Percent_Identity=33.6633663366337, Blast_Score=60, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 26575; Mature: 26444

Theoretical pI: Translated: 5.98; Mature: 5.98

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKRILIVDDEKSIVTLLKYNMENSGFETDVAYNGQEAINKAEASMYDLIVLDLMLPEVD
CCCEEEEEECCCCEEEHHHHCCCCCCCCCCEEECCHHHHHHHHHHHHHHHHHHHHCCCCC
GMEVCRTLRMNQVNTPILMLTAKDEEFDKVLGLEMGADDYLTKPFSPKEVIARVKAILRR
HHHHHHHHHCCCCCCCEEEEEECCHHHHHHHCCCCCCCHHCCCCCCHHHHHHHHHHHHHH
SQLSNNHGFHVLKIGELSIYPERYEAEMSNNIITFTRKEFELLYHLAKHKGKVISRDQLL
HHCCCCCCEEEEEECCEEECCHHHHHHHCCCEEEEEHHHHHHHHHHHHHCCCEECHHHHH
SSVWDYDFIGDTRIVDVHISHLRDKIEPNSKKPVYIKTVRGLGYKMEEPVS
HHHCCCCCCCCCEEEEEEHHHHHHHCCCCCCCCEEEEEECCCCCCCCCCCC
>Mature Secondary Structure 
SKRILIVDDEKSIVTLLKYNMENSGFETDVAYNGQEAINKAEASMYDLIVLDLMLPEVD
CCEEEEEECCCCEEEHHHHCCCCCCCCCCEEECCHHHHHHHHHHHHHHHHHHHHCCCCC
GMEVCRTLRMNQVNTPILMLTAKDEEFDKVLGLEMGADDYLTKPFSPKEVIARVKAILRR
HHHHHHHHHCCCCCCCEEEEEECCHHHHHHHCCCCCCCHHCCCCCCHHHHHHHHHHHHHH
SQLSNNHGFHVLKIGELSIYPERYEAEMSNNIITFTRKEFELLYHLAKHKGKVISRDQLL
HHCCCCCCEEEEEECCEEECCHHHHHHHCCCEEEEEHHHHHHHHHHHHHCCCEECHHHHH
SSVWDYDFIGDTRIVDVHISHLRDKIEPNSKKPVYIKTVRGLGYKMEEPVS
HHHCCCCCCCCCEEEEEEHHHHHHHCCCCCCCCEEEEEECCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1454550; 3036763; 9387221; 9384377; 8045898; 3142862 [H]