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The map label for this gene is rhaB

Identifier: 23097950

GI number: 23097950

Start: 525928

End: 527340

Strand: Direct

Name: rhaB

Synonym: OB0495

Alternate gene names: 23097950

Gene position: 525928-527340 (Clockwise)

Preceding gene: 23097949

Following gene: 23097951

Centisome position: 14.49

GC content: 34.47

Gene sequence:

>1413_bases
ATGCAACAATGTAACTTAGCGGTAGATATAGGAGCTTCCAGTGGAAGAGTTATTGCAGGGTACTTACAAAATGGAAAATT
ACAATTAGAAGAAGTTCATCGTTTTGATAATAAATTAATCGATCTGAACAATTATTTTTGTTGGGATATCGATCGAATTT
ATCAAGAAATATTAATGGGTATTAAATCGGCAGTTGATAATGGATACCAGCCTATAAGTCTTGGAATTGATACGTGGGCG
GTTGATTTTGTTTTGTTAGATGAAAATGACATGCGATTAACAGATGCGGTTTCTTATCGAGACCCACGGACAGACGGAAT
GATGGAGGAAGTCTTCTCTCAAATAAGTAAAGAACGTCTCTATTTAGAGACAGGAATTCAGTTTCAAAAATTTAACACGA
TGTATCAATTACAAGCATTAAAGAATAGCAATCCTGATTTGATCGAGAAAGCAACGAGTTTTCTAATGATACCAGATTAC
TTAAATTTTTTACTTACTGGGAAAAAAGTTAACGAATATACCAATGCAACTACGACTCAATTAGTTAATGCATTTACGAA
AAAATGGGATATCGATTTAATTGAACAGTTAGGTTTTAATTCGAACATGTTCATGGATATTCAACCTCCTGAATCAGTAA
TTGGTAATCTTCGCCCAGAGCTTCAAGAAGAATTAGGTGTTGATTTTAATGTAATCTTACCCGCAACGCATGACACTGGT
TCAGCTGTTGTAGCTGTTCCTGAACAAGAAAATTCCATATATATTAGCTCAGGGACTTGGTCTTTGATCGGGGTGGAGAA
TCATTTTCCAATCTGTACAACCAAGGCACTAGATTATAATTTTACGAATGAAGGCGGAGCGGATTACCGCTATCGTTTTT
TGAAAAACATCATGGGATTATGGATGATTCAAGAAGTAAAGAGAAACTTTAATGATGAATTTGAATTTGCCGATTTTGCT
GCGATGGCAAAAGGAGAATCATTTAAATCGATTGTGGATGTAGATGATGATCGATTCTTAAAACCTGAAAATATGATTGA
GGAAATAAAAGCATATTGTAAGGAAACCAACCAAGCTATACCTCAATCGCCAAGTGAAGTGGCTAAATGTGTATTTAATA
GTTTAGCAGTTAGCTATCAACAAGCGATCTCTCAAATTGAAGAAATTTATGAAATCGACTTTCCGACCATTTATGTTATT
GGTGGCGGATCAAAGAATGAAATGTTAAATCAATTAATAGCAGATACAACAGGAAAAACAGTAATAGCTGGTTTGTCTGA
AGCTACAGCTATTGGGAACTTAATTGTACAAATGATGGCAATCGATCAAATAGATGATATGCAACAAGCTAGACAAATTA
TTAAACATTCATTTGATTTATATACCTATGCAAAAGTAACGATGGAGGGGTAA

Upstream 100 bases:

>100_bases
TTATCATAAACGTACAGAAGGCAACGAAAGATTACTTAACTTGACGATTTTATAGATAGACGGATAGAAGCATTCTATTG
ATTCAAGGAAGGTGAATTAC

Downstream 100 bases:

>100_bases
ATATGGACGTCAAACAAAATTATGAACAAGCGAAAAAACAATATGAAAAATGGGGAGTTAATGTTGAGGATGCGTTAGAG
AAGCTAAAACAAATTCCGAT

Product: rhamnulokinase

Products: NA

Alternate protein names: Rhamnulose kinase

Number of amino acids: Translated: 470; Mature: 470

Protein sequence:

>470_residues
MQQCNLAVDIGASSGRVIAGYLQNGKLQLEEVHRFDNKLIDLNNYFCWDIDRIYQEILMGIKSAVDNGYQPISLGIDTWA
VDFVLLDENDMRLTDAVSYRDPRTDGMMEEVFSQISKERLYLETGIQFQKFNTMYQLQALKNSNPDLIEKATSFLMIPDY
LNFLLTGKKVNEYTNATTTQLVNAFTKKWDIDLIEQLGFNSNMFMDIQPPESVIGNLRPELQEELGVDFNVILPATHDTG
SAVVAVPEQENSIYISSGTWSLIGVENHFPICTTKALDYNFTNEGGADYRYRFLKNIMGLWMIQEVKRNFNDEFEFADFA
AMAKGESFKSIVDVDDDRFLKPENMIEEIKAYCKETNQAIPQSPSEVAKCVFNSLAVSYQQAISQIEEIYEIDFPTIYVI
GGGSKNEMLNQLIADTTGKTVIAGLSEATAIGNLIVQMMAIDQIDDMQQARQIIKHSFDLYTYAKVTMEG

Sequences:

>Translated_470_residues
MQQCNLAVDIGASSGRVIAGYLQNGKLQLEEVHRFDNKLIDLNNYFCWDIDRIYQEILMGIKSAVDNGYQPISLGIDTWA
VDFVLLDENDMRLTDAVSYRDPRTDGMMEEVFSQISKERLYLETGIQFQKFNTMYQLQALKNSNPDLIEKATSFLMIPDY
LNFLLTGKKVNEYTNATTTQLVNAFTKKWDIDLIEQLGFNSNMFMDIQPPESVIGNLRPELQEELGVDFNVILPATHDTG
SAVVAVPEQENSIYISSGTWSLIGVENHFPICTTKALDYNFTNEGGADYRYRFLKNIMGLWMIQEVKRNFNDEFEFADFA
AMAKGESFKSIVDVDDDRFLKPENMIEEIKAYCKETNQAIPQSPSEVAKCVFNSLAVSYQQAISQIEEIYEIDFPTIYVI
GGGSKNEMLNQLIADTTGKTVIAGLSEATAIGNLIVQMMAIDQIDDMQQARQIIKHSFDLYTYAKVTMEG
>Mature_470_residues
MQQCNLAVDIGASSGRVIAGYLQNGKLQLEEVHRFDNKLIDLNNYFCWDIDRIYQEILMGIKSAVDNGYQPISLGIDTWA
VDFVLLDENDMRLTDAVSYRDPRTDGMMEEVFSQISKERLYLETGIQFQKFNTMYQLQALKNSNPDLIEKATSFLMIPDY
LNFLLTGKKVNEYTNATTTQLVNAFTKKWDIDLIEQLGFNSNMFMDIQPPESVIGNLRPELQEELGVDFNVILPATHDTG
SAVVAVPEQENSIYISSGTWSLIGVENHFPICTTKALDYNFTNEGGADYRYRFLKNIMGLWMIQEVKRNFNDEFEFADFA
AMAKGESFKSIVDVDDDRFLKPENMIEEIKAYCKETNQAIPQSPSEVAKCVFNSLAVSYQQAISQIEEIYEIDFPTIYVI
GGGSKNEMLNQLIADTTGKTVIAGLSEATAIGNLIVQMMAIDQIDDMQQARQIIKHSFDLYTYAKVTMEG

Specific function: Metabolism of L-rhamnose; second step. [C]

COG id: COG1070

COG function: function code G; Sugar (pentulose and hexulose) kinases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the rhamnulokinase family

Homologues:

Organism=Escherichia coli, GI1790338, Length=466, Percent_Identity=42.9184549356223, Blast_Score=386, Evalue=1e-108,
Organism=Escherichia coli, GI1789168, Length=472, Percent_Identity=22.0338983050847, Blast_Score=108, Evalue=7e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RHAB_OCEIH (Q8ESX1)

Other databases:

- EMBL:   BA000028
- RefSeq:   NP_691416.1
- ProteinModelPortal:   Q8ESX1
- SMR:   Q8ESX1
- GeneID:   1015764
- GenomeReviews:   BA000028_GR
- KEGG:   oih:OB0495
- NMPDR:   fig|221109.1.peg.499
- HOGENOM:   HBG313195
- OMA:   EEIHRFK
- ProtClustDB:   CLSK873056
- BioCyc:   OIHE221109:OB0495-MONOMER
- BRENDA:   2.7.1.5
- HAMAP:   MF_01535
- InterPro:   IPR000577
- InterPro:   IPR018485
- InterPro:   IPR018484
- InterPro:   IPR013449
- PANTHER:   PTHR10196
- TIGRFAMs:   TIGR02627

Pfam domain/function: PF02782 FGGY_C; PF00370 FGGY_N

EC number: =2.7.1.5

Molecular weight: Translated: 53268; Mature: 53268

Theoretical pI: Translated: 4.19; Mature: 4.19

Prosite motif: NA

Important sites: BINDING 13-13 BINDING 259-259 BINDING 296-296 BINDING 304-304

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQQCNLAVDIGASSGRVIAGYLQNGKLQLEEVHRFDNKLIDLNNYFCWDIDRIYQEILMG
CCCCCEEEEECCCCCCEEEEEECCCCEEHHHHHHHCCCEEECCCEEEECHHHHHHHHHHH
IKSAVDNGYQPISLGIDTWAVDFVLLDENDMRLTDAVSYRDPRTDGMMEEVFSQISKERL
HHHHHCCCCCEEEECCCEEEEEEEEECCCCCEEEHHHCCCCCCCCCHHHHHHHHHHHHHE
YLETGIQFQKFNTMYQLQALKNSNPDLIEKATSFLMIPDYLNFLLTGKKVNEYTNATTTQ
EHHCCCEEHHHHHHHHHHHHCCCCHHHHHHHHHEEECHHHHHHHHCCCHHHHHCCHHHHH
LVNAFTKKWDIDLIEQLGFNSNMFMDIQPPESVIGNLRPELQEELGVDFNVILPATHDTG
HHHHHHHHCCHHHHHHCCCCCCEEEEECCHHHHHCCCCHHHHHHHCCCEEEEEECCCCCC
SAVVAVPEQENSIYISSGTWSLIGVENHFPICTTKALDYNFTNEGGADYRYRFLKNIMGL
CEEEEEECCCCEEEEECCCEEEEEECCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHH
WMIQEVKRNFNDEFEFADFAAMAKGESFKSIVDVDDDRFLKPENMIEEIKAYCKETNQAI
HHHHHHHHCCCCCCCHHHHHHHHCCCCHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCC
PQSPSEVAKCVFNSLAVSYQQAISQIEEIYEIDFPTIYVIGGGSKNEMLNQLIADTTGKT
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHCCCCCE
VIAGLSEATAIGNLIVQMMAIDQIDDMQQARQIIKHSFDLYTYAKVTMEG
EEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEECC
>Mature Secondary Structure
MQQCNLAVDIGASSGRVIAGYLQNGKLQLEEVHRFDNKLIDLNNYFCWDIDRIYQEILMG
CCCCCEEEEECCCCCCEEEEEECCCCEEHHHHHHHCCCEEECCCEEEECHHHHHHHHHHH
IKSAVDNGYQPISLGIDTWAVDFVLLDENDMRLTDAVSYRDPRTDGMMEEVFSQISKERL
HHHHHCCCCCEEEECCCEEEEEEEEECCCCCEEEHHHCCCCCCCCCHHHHHHHHHHHHHE
YLETGIQFQKFNTMYQLQALKNSNPDLIEKATSFLMIPDYLNFLLTGKKVNEYTNATTTQ
EHHCCCEEHHHHHHHHHHHHCCCCHHHHHHHHHEEECHHHHHHHHCCCHHHHHCCHHHHH
LVNAFTKKWDIDLIEQLGFNSNMFMDIQPPESVIGNLRPELQEELGVDFNVILPATHDTG
HHHHHHHHCCHHHHHHCCCCCCEEEEECCHHHHHCCCCHHHHHHHCCCEEEEEECCCCCC
SAVVAVPEQENSIYISSGTWSLIGVENHFPICTTKALDYNFTNEGGADYRYRFLKNIMGL
CEEEEEECCCCEEEEECCCEEEEEECCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHH
WMIQEVKRNFNDEFEFADFAAMAKGESFKSIVDVDDDRFLKPENMIEEIKAYCKETNQAI
HHHHHHHHCCCCCCCHHHHHHHHCCCCHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCC
PQSPSEVAKCVFNSLAVSYQQAISQIEEIYEIDFPTIYVIGGGSKNEMLNQLIADTTGKT
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHCCCCCE
VIAGLSEATAIGNLIVQMMAIDQIDDMQQARQIIKHSFDLYTYAKVTMEG
EEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12235376