Click here to switch to the map view.

The map label for this gene is iolF [H]

Identifier: 23097949

GI number: 23097949

Start: 524398

End: 525699

Strand: Direct

Name: iolF [H]

Synonym: OB0494

Alternate gene names: 23097949

Gene position: 524398-525699 (Clockwise)

Preceding gene: 23097948

Following gene: 23097950

Centisome position: 14.44

GC content: 39.02

Gene sequence:

>1302_bases
ATGAGCAAGCAAAGATTTGCAGCTAAAAATGTAACTGGCTGGAAAGCGACTATTGCAATTGCGATGGCGAATTATATTGA
AGCCGGGTCAATTATTGCTGCAGCTAGTAGTCTTACATTATGGCAAGCCTATCTTGGGTTTGATAGTTTAGGTGTTGGGT
TGCTTAGTGCGTTAAGTGCGAATGCTTTAGGTGCGGCGATTGGTGCGCTTATTGGTGGACCATTAACAGATAAATATGGA
AGAAAGATAATTTTTAGTTATGATTTATTAGTGTATATGATTGGTGTTGCTTTGATTGCGGCATCTGTAAACTTCCCTAT
GTTGTTAATTGGTACGATTATTACTGGTATCGCGGTAGGGGCAGGAGTGCCGGTATCTTGGACTTATATTGCAGAAGAAT
CACCAAAGAAAAAAAGAGCCGCGCATGTTGGTGCAGCTCAATTAGCCTGGTCGATCGGACCGATGATTACATTTGCTTTA
GCAGTACTTGTAGCACCATTAGAGTTATTAGGATCGAGATTAATCTTTATCCACTTATTTATCGTTGCTGGTTTAGCTTT
ATATATTCGTAGAGGTCTTCCGGAATCCAAGATTTGGGAAGAGCAAAAAGCAAGAGACGATGCGGATAAAGCAAAAGGTA
TTGTTAAAAAAGGTACATTGAAAGAATTATTTACACTGAAACCAAACAGAGAAGCATTATTCTTACTACTTGGTATTTAC
TTATTCTGGAACTTAACAGCGGGAGCAATGGGATACTTTATGCCATACATATACGAAAATGTAGGTGGCTTAAGTAATAT
GGAAGCAAACTTATTACAGTCGTTCCTATGGATGTTCACCGTGTTAACCACCTTCTTTATCTTCATGAAATTAGGGGATA
AAATAAGCCGTAAAACACTGTTTACGATAGGTGCACTTATGGGTGTAGCTGCCTGGATAATCTTAACGTTTATGCCGATG
ACTTGGCCGACATTGATTGCCTTTGTTATTTTGTGGGGATCTGCAGCTGGTATTGGTGCTCAAGCGTTTTACGCATTATG
GACGAGTGAATTATTCCCAACAAGATATCGTGCTACCGCGCAAGGATTTATGTACTTTATTGTACGAACAGGAATTGCAC
TTTGGTCAGTAGTATTACCAGTAATTATGGACACACTAGGTTTTGTGGTTGCGGGCATTGTGATGATTATATTCCTTGTT
ATTCATTTAGTTATCGGAGTTGTTCTAGCTCCTGATACGAGAGGTAAAACATTAACAGAAATTGAAGAAGAGCGTTATGG
TAAAGAACGAATAGCGAATTAA

Upstream 100 bases:

>100_bases
AAGTTTATGAAGCCCGTTATGAAAACGAATTCAGATGATAGCCCTGTATCAACGGATTTAACAGAAGTGTTCCATATGGA
TTAAGAGGAGGGAATAAAAA

Downstream 100 bases:

>100_bases
TAGTATACAACAAAAAAAGGTAACGGAAAATTCGTTGCCTTTTTGTTTTTTTTTTATTCTTTTTACTAACTAAAAAACAA
AACATCTTTGTTTATTTTGG

Product: inositol transport protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 433; Mature: 432

Protein sequence:

>433_residues
MSKQRFAAKNVTGWKATIAIAMANYIEAGSIIAAASSLTLWQAYLGFDSLGVGLLSALSANALGAAIGALIGGPLTDKYG
RKIIFSYDLLVYMIGVALIAASVNFPMLLIGTIITGIAVGAGVPVSWTYIAEESPKKKRAAHVGAAQLAWSIGPMITFAL
AVLVAPLELLGSRLIFIHLFIVAGLALYIRRGLPESKIWEEQKARDDADKAKGIVKKGTLKELFTLKPNREALFLLLGIY
LFWNLTAGAMGYFMPYIYENVGGLSNMEANLLQSFLWMFTVLTTFFIFMKLGDKISRKTLFTIGALMGVAAWIILTFMPM
TWPTLIAFVILWGSAAGIGAQAFYALWTSELFPTRYRATAQGFMYFIVRTGIALWSVVLPVIMDTLGFVVAGIVMIIFLV
IHLVIGVVLAPDTRGKTLTEIEEERYGKERIAN

Sequences:

>Translated_433_residues
MSKQRFAAKNVTGWKATIAIAMANYIEAGSIIAAASSLTLWQAYLGFDSLGVGLLSALSANALGAAIGALIGGPLTDKYG
RKIIFSYDLLVYMIGVALIAASVNFPMLLIGTIITGIAVGAGVPVSWTYIAEESPKKKRAAHVGAAQLAWSIGPMITFAL
AVLVAPLELLGSRLIFIHLFIVAGLALYIRRGLPESKIWEEQKARDDADKAKGIVKKGTLKELFTLKPNREALFLLLGIY
LFWNLTAGAMGYFMPYIYENVGGLSNMEANLLQSFLWMFTVLTTFFIFMKLGDKISRKTLFTIGALMGVAAWIILTFMPM
TWPTLIAFVILWGSAAGIGAQAFYALWTSELFPTRYRATAQGFMYFIVRTGIALWSVVLPVIMDTLGFVVAGIVMIIFLV
IHLVIGVVLAPDTRGKTLTEIEEERYGKERIAN
>Mature_432_residues
SKQRFAAKNVTGWKATIAIAMANYIEAGSIIAAASSLTLWQAYLGFDSLGVGLLSALSANALGAAIGALIGGPLTDKYGR
KIIFSYDLLVYMIGVALIAASVNFPMLLIGTIITGIAVGAGVPVSWTYIAEESPKKKRAAHVGAAQLAWSIGPMITFALA
VLVAPLELLGSRLIFIHLFIVAGLALYIRRGLPESKIWEEQKARDDADKAKGIVKKGTLKELFTLKPNREALFLLLGIYL
FWNLTAGAMGYFMPYIYENVGGLSNMEANLLQSFLWMFTVLTTFFIFMKLGDKISRKTLFTIGALMGVAAWIILTFMPMT
WPTLIAFVILWGSAAGIGAQAFYALWTSELFPTRYRATAQGFMYFIVRTGIALWSVVLPVIMDTLGFVVAGIVMIIFLVI
HLVIGVVLAPDTRGKTLTEIEEERYGKERIAN

Specific function: Minor myo-inositol uptake transporter [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family [H]

Homologues:

Organism=Escherichia coli, GI87082404, Length=306, Percent_Identity=24.8366013071895, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1786229, Length=416, Percent_Identity=24.5192307692308, Blast_Score=68, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI212645980, Length=399, Percent_Identity=26.0651629072682, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI17737451, Length=407, Percent_Identity=25.0614250614251, Blast_Score=71, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24652312, Length=407, Percent_Identity=25.0614250614251, Blast_Score=71, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR005829 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 47195; Mature: 47064

Theoretical pI: Translated: 9.96; Mature: 9.96

Prosite motif: PS50850 MFS ; PS00217 SUGAR_TRANSPORT_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKQRFAAKNVTGWKATIAIAMANYIEAGSIIAAASSLTLWQAYLGFDSLGVGLLSALSA
CCCCHHHHCCCCCHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHH
NALGAAIGALIGGPLTDKYGRKIIFSYDLLVYMIGVALIAASVNFPMLLIGTIITGIAVG
HHHHHHHHHHHCCCCCHHHCCEEEEHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHC
AGVPVSWTYIAEESPKKKRAAHVGAAQLAWSIGPMITFALAVLVAPLELLGSRLIFIHLF
CCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IVAGLALYIRRGLPESKIWEEQKARDDADKAKGIVKKGTLKELFTLKPNREALFLLLGIY
HHHHHHHHHHCCCCHHHHHHHHHHCCCHHHHHHHHHCCHHHHHHHCCCCHHHHHHHHHHH
LFWNLTAGAMGYFMPYIYENVGGLSNMEANLLQSFLWMFTVLTTFFIFMKLGDKISRKTL
HHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FTIGALMGVAAWIILTFMPMTWPTLIAFVILWGSAAGIGAQAFYALWTSELFPTRYRATA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCHHHHHHH
QGFMYFIVRTGIALWSVVLPVIMDTLGFVVAGIVMIIFLVIHLVIGVVLAPDTRGKTLTE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCHHHH
IEEERYGKERIAN
HHHHHCCHHHCCC
>Mature Secondary Structure 
SKQRFAAKNVTGWKATIAIAMANYIEAGSIIAAASSLTLWQAYLGFDSLGVGLLSALSA
CCCHHHHCCCCCHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHH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HHHHHCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7952181; 9384377; 1761221; 11807058 [H]