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The map label for this gene is dtd [H]

Identifier: 22127671

GI number: 22127671

Start: 4219550

End: 4219987

Strand: Reverse

Name: dtd [H]

Synonym: y3800

Alternate gene names: 22127671

Gene position: 4219987-4219550 (Counterclockwise)

Preceding gene: 22127672

Following gene: 22127668

Centisome position: 91.72

GC content: 48.86

Gene sequence:

>438_bases
ATGATTGCGTTGATTCAACGGGCGCTTAGCGCCAGTGTCGTGGTCGAAGGGAATATCGTGGGTGAAATTGGCCCTGGCCT
ACTGGTATTACTCGGCGTTGAGCAAGGAGATACTGAGCAAAAAGCACAGCGTTTATGTGAGCGGGTACTGGGGTATCGGA
TTTTTAGCGATGAGAATGACAAAATGAATCTCAACGTCCAGCAAGCTGGGGGCAGTGTGCTGGTGGTTTCGCAATTTACC
TTGGTTGCTGATACTCAAAAGGGCATGAGACCCAGTTTTTCTCGTGGTGCGATCCCGCAAGAAGCTGACCGGCTTTATCA
GTATTTTGTTGCTCAGTGCCGTGAGCGTGGTGTAAAAACGGAAACAGGGCTTTTTGCAGCAGATATGAAAGTTAGCTTGG
TAAACGATGGTCCGGTAACTTTCTGGTTGCAAGTCTAG

Upstream 100 bases:

>100_bases
GTTATTAGGTGCGGAAATCACCGTGACATTGGGTGAATACCGCGCCGAGCGCCATCACGCGAAGAGCGTCACCACCCAGA
GTCCGGAGATGTAAGGCATT

Downstream 100 bases:

>100_bases
AGATGAATGTCAACGACGGATGAAAAGTGATCCACTTATATCTCCACCAACGGCCCAATATTGATCCACCGTTTTACTCA
GGATTAGCTTCTGCTATAAC

Product: D-tyrosyl-tRNA(Tyr) deacylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 145; Mature: 145

Protein sequence:

>145_residues
MIALIQRALSASVVVEGNIVGEIGPGLLVLLGVEQGDTEQKAQRLCERVLGYRIFSDENDKMNLNVQQAGGSVLVVSQFT
LVADTQKGMRPSFSRGAIPQEADRLYQYFVAQCRERGVKTETGLFAADMKVSLVNDGPVTFWLQV

Sequences:

>Translated_145_residues
MIALIQRALSASVVVEGNIVGEIGPGLLVLLGVEQGDTEQKAQRLCERVLGYRIFSDENDKMNLNVQQAGGSVLVVSQFT
LVADTQKGMRPSFSRGAIPQEADRLYQYFVAQCRERGVKTETGLFAADMKVSLVNDGPVTFWLQV
>Mature_145_residues
MIALIQRALSASVVVEGNIVGEIGPGLLVLLGVEQGDTEQKAQRLCERVLGYRIFSDENDKMNLNVQQAGGSVLVVSQFT
LVADTQKGMRPSFSRGAIPQEADRLYQYFVAQCRERGVKTETGLFAADMKVSLVNDGPVTFWLQV

Specific function: Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine [H]

COG id: COG1490

COG function: function code J; D-Tyr-tRNAtyr deacylase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DTD family [H]

Homologues:

Organism=Homo sapiens, GI30795227, Length=147, Percent_Identity=36.734693877551, Blast_Score=86, Evalue=1e-17,
Organism=Escherichia coli, GI1790320, Length=145, Percent_Identity=75.8620689655172, Blast_Score=226, Evalue=4e-61,
Organism=Caenorhabditis elegans, GI115533292, Length=143, Percent_Identity=37.7622377622378, Blast_Score=87, Evalue=2e-18,
Organism=Saccharomyces cerevisiae, GI6319982, Length=146, Percent_Identity=36.986301369863, Blast_Score=97, Evalue=1e-21,
Organism=Drosophila melanogaster, GI281361569, Length=146, Percent_Identity=36.986301369863, Blast_Score=89, Evalue=7e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003732 [H]

Pfam domain/function: PF02580 Tyr_Deacylase [H]

EC number: NA

Molecular weight: Translated: 15863; Mature: 15863

Theoretical pI: Translated: 4.88; Mature: 4.88

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIALIQRALSASVVVEGNIVGEIGPGLLVLLGVEQGDTEQKAQRLCERVLGYRIFSDEND
CHHHHHHHHCCEEEEECCEEECCCCCEEEEEECCCCCHHHHHHHHHHHHHCEEEECCCCC
KMNLNVQQAGGSVLVVSQFTLVADTQKGMRPSFSRGAIPQEADRLYQYFVAQCRERGVKT
EEEEEEECCCCCEEEEEEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCC
ETGLFAADMKVSLVNDGPVTFWLQV
CCCEEEECEEEEEECCCCEEEEEEC
>Mature Secondary Structure
MIALIQRALSASVVVEGNIVGEIGPGLLVLLGVEQGDTEQKAQRLCERVLGYRIFSDEND
CHHHHHHHHCCEEEEECCEEECCCCCEEEEEECCCCCHHHHHHHHHHHHHCEEEECCCCC
KMNLNVQQAGGSVLVVSQFTLVADTQKGMRPSFSRGAIPQEADRLYQYFVAQCRERGVKT
EEEEEEECCCCCEEEEEEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCC
ETGLFAADMKVSLVNDGPVTFWLQV
CCCEEEECEEEEEECCCCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA